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Topic:Disease

The study of diseases in horses encompasses a wide range of conditions affecting equine health, including infectious diseases, metabolic disorders, and genetic abnormalities. These diseases can impact various systems within the horse, such as respiratory, gastrointestinal, and musculoskeletal systems, and can lead to significant health challenges. Research in this area focuses on understanding the pathophysiology, diagnosis, prevention, and treatment of equine diseases. Common diseases studied include equine influenza, equine herpesvirus, and laminitis. This page provides access to peer-reviewed research studies and scholarly articles that explore the etiology, clinical presentation, and management strategies of diseases in horses, contributing to the advancement of equine veterinary medicine.
Persistent dorsal displacement of the soft palate attributable to a frenulum of the epiglottis in a racing Thoroughbred.
Journal of the American Veterinary Medical Association    September 4, 2007   Volume 231, Issue 5 751-754 doi: 10.2460/javma.231.5.751
Moorman VJ, Marshall JF, Jann HW.A 7-year-old sexually intact male Thoroughbred racehorse was evaluated because of exercise intolerance, respiratory tract noise, and coughing when eating. Results: A persistent dorsal displacement of the soft palate was identified during endoscopic examination of the upper portions of the respiratory tract. Radiography of the pharyngeal and laryngeal regions revealed a hypoplastic epiglottis that was ventral to, and not in contact with, the soft palate. The horse was anesthetized, and an oral endoscopic examination revealed a subepiglottic frenulum that had resulted in the dorsal displacement ...
Exercise-induced pulmonary haemorrhage (EIPH): mechanistic bases and therapeutic interventions.
Equine veterinary journal    August 29, 2007   Volume 39, Issue 4 292-293 doi: 10.2746/042516407x204078
Poole DC, Epp TS, Erickson HH.No abstract available
Acute in vivo interactions of Helicobacter equorum with its equine host.
Equine veterinary journal    August 29, 2007   Volume 39, Issue 4 370-372 doi: 10.2746/042516407x206391
Moyaert H, Decostere A, Pasmans F, Baele M, Ceelen L, Smits K, Ducatelle R, Haesebrouck F.A novel urease-negative Helicobacter species has been isolated from faecal samples of clinically healthy horses, but no information is available about the main sites of colonisation in the equine gastrointestinal tract nor is the pathogenic potential of this microorganism known. An experimental infection in horses was therefore carried out. Methods: Four horses were infected with H. equorum strain CCUG 52199T and subjected to euthanasia at 10 (n = 2) and 30 days (n = 2) post inoculation. A fifth animal was inoculated with phosphate buffered saline and used as control. Gastrointestinal samples ...
Diagnostic evaluation of real-time PCR in the detection of Rhodococcus equi in faeces and nasopharyngeal swabs from foals with pneumonia.
The Veterinary record    August 28, 2007   Volume 161, Issue 8 272-275 doi: 10.1136/vr.161.8.272
Pusterla N, Wilson WD, Mapes S, Leutenegger CM.No abstract available
Culicoides species attracted to horses with and without insect hypersensitivity.
Veterinary journal (London, England : 1997)    August 28, 2007   Volume 178, Issue 1 91-97 doi: 10.1016/j.tvjl.2007.07.005
van der Rijt R, van den Boom R, Jongema Y, van Oldruitenborgh-Oosterbaan MM.The aims of this study were to determine (1) which species of Culicoides is most commonly attracted to horses, (2) whether horses suffering insect hypersensitivity attract more Culicoides spp. than unaffected horses, and (3) the times when Culicoides spp. are most active. Horses affected by insect hypersensitivity and unaffected horses were placed inside mosquito netting tents for 30 min at different times of the day. All Culicoides spp. trapped inside the tents were collected and identified. C. obsoletus was the most common species found, followed by C. pulicaris. Healthy horses attracted sli...
Phylogeny of trichostome ciliates (Ciliophora, Litostomatea) endosymbiotic in the Yakut horse (Equus caballus).
European journal of protistology    August 27, 2007   Volume 43, Issue 4 319-328 doi: 10.1016/j.ejop.2007.06.005
Strüder-Kypke MC, Kornilova OA, Lynn DH.Ciliates of the subclass Trichostomatia inhabit the fermentative regions of the digestive tract of herbivores. Most available small subunit ribosomal RNA (SSrRNA) gene sequences of trichostomes are from species isolated from the rumen of cattle or sheep and from marsupials. No ciliate species endosymbiotic in horses has yet been analyzed. We have sequenced the SSrRNA genes of five ciliate species, isolated from the cecum and colon of four Yakut horses: Cycloposthium edentatum, Cycloposthium ishikawai, Tripalmaria dogieli, Cochliatoxum periachtum, and Paraisotricha colpoidea. Based on their mor...
Occurrence of anthelmintic resistant equine cyathostome populations in central and southern Italy.
Preventive veterinary medicine    August 24, 2007   Volume 82, Issue 3-4 314-320 doi: 10.1016/j.prevetmed.2007.07.006
Traversa D, Klei TR, Iorio R, Paoletti B, Lia RP, Otranto D, Sparagano OA, Giangaspero A.In the present survey, 276 horses bred on 16 farms located in central and southern Italy were investigated for the presence of drug resistant cyathostomes by a Fecal Egg Count Reduction Test (FECRT). Sixteen to 20 animals were selected on each farm and randomly assigned to one of four equally sized treatment groups. Groups were treated with fenbendazole, pyrantel pamoate, ivermectin or moxidectin. Resistance to fenbendazole was declared on six farms (37.5%) and suspected in two farms (12.5%), with FECR values ranging from 41% to 88.3%. Resistance to pyrantel was found in two farms (12.5%) and ...
Plasma adrenocorticotropin, cortisol, and adrenocorticotropin/cortisol ratios in septic and normal-term foals.
Journal of veterinary internal medicine    August 22, 2007   Volume 21, Issue 4 791-796 doi: 10.1892/0891-6640(2007)21[791:pacacr]2.0.co;2
Gold JR, Divers TJ, Barton MH, Lamb SV, Place NJ, Mohammed HO, Bain FT.Little information exists on the hypothalamic-pituitary-adrenal axis in septic foals. Objective: The plasma concentrations of adrenocorticotropin (ACTH) and cortisol are expected to be higher in septic foals as compared to normal foals. The concentrations of hormones in septic foals also are expected to differ further depending upon survival. Methods: Twenty-eight control foals and 46 septic foals 11 or a positive blood culture. The control foals were age matched to the septic foals in the study. ACTH and cortisol concentrations were measured by a chemiluminescent immunoassay system. Results: ...
Use of Fourier-transform infrared spectroscopy for the diagnosis of failure of transfer of passive immunity and measurement of immunoglobulin concentrations in horses.
Journal of veterinary internal medicine    August 22, 2007   Volume 21, Issue 4 828-834 doi: 10.1892/0891-6640(2007)21[828:uofisf]2.0.co;2
Riley CB, McClure JT, Low-Ying S, Shaw RA.The economic, accurate, and rapid screening of foals for failure of transfer of passive immunity (FPT) is essential to ensure timely intervention. Objective: Infrared (IR) spectroscopy of foal sera and pattern recognition may be used to diagnose FPT and quantify serum IgG. Methods: Sera from 194 foals (24-72 hours) with serum immunoglobulin G (IgG) concentrations determined previously by radial immunodiffusion assay (RID) were used. Methods: IR spectra were recorded for the serum samples, and the data were randomly divided into training and independent test sets, each containing both FPT-posit...
Equine disease surveillance, January to March 2007.
The Veterinary record    August 19, 2007   Volume 161, Issue 3 79-82 doi: 10.1136/vr.161.3.79
No abstract available
Treatment in the field of 27 horses with epiglottic entrapment.
The Veterinary record    August 19, 2007   Volume 161, Issue 6 187-189 doi: 10.1136/vr.161.6.187
Russell T, Wainscott M.Twenty-seven horses were treated for epiglottic entrapment by using an oral, hand-assisted bistoury knife technique, under general anaesthesia; 26 of them returned successfully to racing, but one developed a permanently displaced soft palate. After the surgery 13 of the horses had an increased handicap rating and 13 had a decreased rating.
Serosurvey of West Nile virus in equids and bovids in Spain.
The Veterinary record    August 19, 2007   Volume 161, Issue 6 212 doi: 10.1136/vr.161.6.212
Jiménez-Clavero MA, Tejedor CG, Rojo G, Soriguer R, Figuerola J.No abstract available
Theriogenology question of the month. Bilateral testicular neoplasia.
Journal of the American Veterinary Medical Association    August 19, 2007   Volume 231, Issue 4 531-534 doi: 10.2460/javma.231.4.531
No abstract available
Non-specific haemolytic alloantibody causing equine neonatal isoerythrolysis.
The Veterinary record    August 19, 2007   Volume 161, Issue 6 202-204 doi: 10.1136/vr.161.6.202
de Graaf-Roelfsema E, van der Kolk JH, Boerma S, van Haeringen H.No abstract available
Prevalence of equine herpesvirus-1 infection among Thoroughbreds residing on a farm on which the virus was endemic.
Journal of the American Veterinary Medical Association    August 19, 2007   Volume 231, Issue 4 577-580 doi: 10.2460/javma.231.4.577
Brown JA, Mapes S, Ball BA, Hodder AD, Liu IK, Pusterla N.To determine the incidence of equine herpesvirus-1 (EHV-1) infection among Thoroughbreds residing on a farm on which the virus was known to be endemic. Methods: Prospective cohort study. Methods: 10 nonpregnant mares, 8 stallions, 16 weanlings, 11 racehorses, and 30 pregnant mares and their foals born during the 2006 foaling season. Methods: Blood and nasopharygeal swab samples were collected every 3 to 5 weeks for 9 months, and placenta and colostrum samples were collected at foaling. All samples were submitted for testing for EHV-1 DNA with a PCR assay. A type-specific EHV-1 ELISA was used t...
Cell phenotypic variation in normal and damaged tendons.
International journal of experimental pathology    August 19, 2007   Volume 88, Issue 4 227-235 doi: 10.1111/j.1365-2613.2007.00549.x
Clegg PD, Strassburg S, Smith RK.Injuries to tendons are common in both human athletes as well as in animals, such as the horse, which are used for competitive purposes. Furthermore, such injuries are also increasing in prevalence in the ageing, sedentary population. Tendon diseases often respond poorly to treatment and require lengthy periods of rehabilitation. The tendon has a unique extracellular matrix, which has developed to withstand the mechanical demands of such tensile-load bearing structures. Following injury, any repair process is inadequate and results in tissue that is distinct from original tendon tissue. There ...
The diversity of coliphages and coliforms in horse feces reveals a complex pattern of ecological interactions.
Applied and environmental microbiology    August 17, 2007   Volume 73, Issue 19 5975-5981 doi: 10.1128/AEM.01145-07
Golomidova A, Kulikov E, Isaeva A, Manykin A, Letarov A.The diversity of coliphages and indigenous coliform strains (ICSs) simultaneously present in horse feces was investigated by culture-based and molecular methods. The richness of coliforms (as estimated by the Chao1 method) is about 1,000 individual ICSs distinguishable by genomic fingerprinting present in a single sample of feces. This unexpectedly high value indicates that some factor limits the competition of coliform bacteria in the horse gut microbial system. In contrast, the diversity of phages active against any selected ICS is generally limited to one to three viral genotypes present in...
Pro-inflammatory and antiviral cytokine expression in vaccinated and unvaccinated horses exposed to equine influenza virus.
Vaccine    August 17, 2007   Volume 25, Issue 41 7056-7064 doi: 10.1016/j.vaccine.2007.07.059
Quinlivan M, Nelly M, Prendergast M, Breathnach C, Horohov D, Arkins S, Chiang YW, Chu HJ, Ng T, Cullinane A.Most studies of the cytokine response to influenza virus infection have been carried out in human, porcine and murine models, however the data available on equine cytokines is limited. An experimental challenge study was undertaken in unvaccinated naïve horses and horses vaccinated with a commercial inactivated influenza vaccine. The humoral antibody response to vaccination and virus challenge was measured by single radial haemolysis (SRH) assay and clinical signs of influenza and viral shedding were monitored post-challenge. Levels of three equine pro-inflammatory cytokines interleukin (IL)-...
Repair of sinocutaneous fistulae in two horses.
Australian veterinary journal    August 10, 2007   Volume 85, Issue 8 341-344 doi: 10.1111/j.1751-0813.2007.00150.x
Charman RE, Vasey JR.Chronic facial defects extending into the sinuses of two mares were repaired using periosteal flaps. Partial osseous bridging was established over the defects following repair. Previous attempts to close the defects with skin alone had failed. A periosteal flap is a simple surgical technique that provides the foundations for successful repair, despite the chronicity of some fistulae.
Left- and right-sided laparoscopic-assisted nephrectomy in standing horses with unilateral renal disease.
Veterinary surgery : VS    August 10, 2007   Volume 36, Issue 6 568-572 doi: 10.1111/j.1532-950X.2007.00306.x
Röcken M, Mosel G, Stehle C, Rass J, Litzke LF.To describe a technique for, and outcome after, left- or right-sided laparoscopic-assisted nephrectomy in standing horses with unilateral renal disease. Methods: Clinical report. Methods: Horses (n=3) with unilateral renal disease. Methods: Horses were sedated with detomidine (0.01 mg/kg intravenously [IV]) and levomethadone (0.05 mg/kg IV). Paravertebral anesthesia and infiltration-anesthesia with 2% lidocaine were used to create a surgical field incorporating the 17th intercostal space and paralumbar fossa. Two separate, ipsilateral portals and a mini-laparotomy were used. The perirenal peri...
Lentzea kentuckyensis sp. nov., of equine origin.
International journal of systematic and evolutionary microbiology    August 9, 2007   Volume 57, Issue Pt 8 1780-1783 doi: 10.1099/ijs.0.64245-0
Labeda DP, Donahue JM, Sells SF, Kroppenstedt RM.A novel actinomycete, designated strain LDDC 2876-05(T), was isolated from an equine placenta during the course of routine diagnostic tests for nocardioform placentitis. In a preliminary study, the strain was observed to be phylogenetically distinct from the genera Crossiella and Amycolatopsis and probably a member of the genus Lentzea. A polyphasic study of strain LDDC 2876-05(T) confirmed its identification as a member of Lentzea on the basis of its chemotaxonomic and morphological similarity to all of the known species of the genus. Moreover, the strain could be distinguished from other spe...
Papillary renal adenoma of distal nephron differentiation in a horse.
The Journal of veterinary medical science    August 7, 2007   Volume 69, Issue 7 763-765 doi: 10.1292/jvms.69.763
Matsuda K, Kousaka Y, Nagamine N, Tsunoda N, Taniyama H.A 20-year-old thoroughbred mare had a mass in the right kidney. The mass was encapsulated with fibrous capsule and composed of variably-sized papillary projections lined by a single layer of flattened to cuboidal neoplastic epithelial cells with no cytological and nuclear atypia. Immunohistochemically, the neoplastic cells were broadly positive for cytokeratin AE1/AE3 and granular staining for alpha-1-antitrypsin was focally detected; this immunohistochemical property was similar to that of the normal distal nephron. From these results, this case was diagnosed as papillary renal adenoma of dis...
Characterization and structure analysis of a novel bacteriocin, lacticin Z, produced by Lactococcus lactis QU 14.
Bioscience, biotechnology, and biochemistry    August 7, 2007   Volume 71, Issue 8 1984-1992 doi: 10.1271/bbb.70169
Iwatani S, Zendo T, Yoneyama F, Nakayama J, Sonomoto K.A novel bacteriocin, lacticin Z, produced by Lactococcus lactis QU 14 isolated from a horse's intestinal tract was identified. Lacticin Z was purified through a three step procedure comprised of hydrophobic-interaction, cation-exchange chromatography, and reverse-phase HPLC. ESI-TOF MS determined the molecular mass of lacticin Z to be 5,968.9 Da. The primary structure of lacticin Z was found to consist of 53 amino acid residues without any leader sequence or signal peptide. Lacticin Z showed homology to lacticin Q from L. lactis QU 5, aureocin A53 from Staphylococcus aureus A53, and mutacin BH...
Equine rescue and response activities in Louisiana in the aftermath of Hurricanes Katrina and Rita.
Journal of the American Veterinary Medical Association    August 3, 2007   Volume 231, Issue 3 384-392 doi: 10.2460/javma.231.3.384
McConnico RS, French DD, Clark B, Mortensen KE, Littlefield M, Moore RM.No abstract available
Congenital retrosternal (Morgagni) diaphragmatic hernias in three horses.
Journal of the American Veterinary Medical Association    August 3, 2007   Volume 231, Issue 3 427-432 doi: 10.2460/javma.231.3.427
Pauwels FF, Hawkins JF, MacHarg MA, Rothenbuhler RD, Baird DK, Moulton JS.3 Horses were examined and treated because of sudden onset of signs of abdominal pain. Results: All horses had a retrosternal (Morgagni) hernia involving the right side of the diaphragm. In each horse, the large colon was incarcerated in a right muscular defect in the diaphragm with a large hernial sac. Results: Definitive surgical repair of the hernia was not performed during the initial celiotomy. The hernia was repaired with mesh herniorrhaphy, but without resection of the hernia sac in 2 horses. For 1 horse, conservative management was applied. In the 2 horses treated with surgical correct...
An investigation of equine infectious anaemia infection in the central Anatolia region of Turkey.
Journal of the South African Veterinary Association    August 2, 2007   Volume 78, Issue 1 12-14 doi: 10.4102/jsava.v78i1.279
Yapklç O, Yavru S, Kale M, Bulut O, Simşek A, Sahna KC.In this study, 162 horses, 80 donkeys and 51 mule serum samples were collected in Konya city. Additionally, 64 horse serum samples from Ankara and 49 samples from Kayseri city were included in the study. A total of 406 serum samples were examined by agar gel immunodiffusion (AGID) and enzyme-linked immunosorbent assay (ELISA) for antibody to equine infectious anaemia virus (EIAV) and no positive result was detected.
Correlation between colic and antibody levels against Anoplocephala perfoliata in horses in The Netherlands.
Tijdschrift voor diergeneeskunde    July 26, 2007   Volume 132, Issue 13 508-512 
Boswinkel M, Sloet van Oldruitenborgh-Oosterbaan MM.The importance of Anoplocephala perfoliata in horses with colic was studied in 139 horses referred for colic and 139 control horses with no signs of colic for at least three years. The serodiagnostic method of Proudman and Trees, which measures the level of A. perfoliata antibody, was used to detect A. perfoliata infection. Thirty-two horses were examined at necropsy, to determine whether the presence of A. perfoliata in the ileocaecal region was associated with the A. perfoliata antibody level. The mean A. perfoliata antibody level was significantly higher in horses with colic than in horses ...
Theriogenology question of the month. Remnants of paramesonephric ducts.
Journal of the American Veterinary Medical Association    July 17, 2007   Volume 231, Issue 2 213-215 doi: 10.2460/javma.231.2.213
Kutzler MA, Hofmaster IL.No abstract available
Relationship between hair elements and severity of atrioventricular block in horses.
Biological trace element research    July 13, 2007   Volume 115, Issue 3 255-264 doi: 10.1007/BF02686000
Suzuki K, Yamaya Y, Asano K, Chiba M, Sera K, Matsumoto T, Sakai T, Asano R.The aim of this study was to investigate the relationships between the mean concentrations of trace elements and the severity of the second-degree atrioventricular (AV) block in the mane hair of horses. Electrocardiographs of horses were continually recorded for 6 h using a holter cardiac monitor to determine dropped ventricular beats (DVBs) which can be used as an indicator of the severity of the AV block. Mane hair Ca, Cu, Mg, and Zn concentrations were measured by the particle-induced X-ray emission method. The Zn/Cu ratio and Ca concentration in mane hair were significantly and positively ...
[Role of IgE-dependent reactions in atopic dermatitis].
Medycyna wieku rozwojowego    July 13, 2007   Volume 11, Issue 2 Pt 1 135-138 
Dynowski J, Wasowska-Królikowska K, Modzelewska-Hołyńska M, Tomaszewska M, Funkowicz M.Atopic dermatitis is a disease of multifactorial pathogenesis. Objective: of the study was to establish the most common allergens responsible for development of atopic symptoms in children with atopic dermatitis. Methods: the study complied 36 children aged 4 months - 3 years treated in the Department of Children Allergology, Gastroenterology and Nutrition because of atopic dermatitis. With each case the patient and family history of atopy was collected and basic laboratory tests were conducted (including total IgE and specific IgE using Polly Check system). Results: eosinophilia was found in ...