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Topic:Epidemiology

Epidemiology in horses involves the study of the distribution and determinants of health-related states and events in equine populations. It encompasses the investigation of patterns, causes, and effects of diseases and health conditions within horse populations. This field of study aims to identify risk factors for disease and targets for preventive healthcare. Key components of equine epidemiology include disease surveillance, outbreak investigation, and the study of disease dynamics within herds or regions. Research in this area often focuses on infectious diseases, zoonotic diseases, and the impact of environmental factors on equine health. This page compiles peer-reviewed research studies and scholarly articles that explore various aspects of epidemiology in horses, including disease prevalence, transmission pathways, and strategies for disease prevention and control.
Prepurchase evaluation of horses: 134 cases (1988-1990).
Journal of the American Veterinary Medical Association    October 1, 1992   Volume 201, Issue 7 1061-1067 
Dart AJ, Snyder JR, Pascoe JR, Meagher DM, Wilson WD.To quantify some components of prepurchase evaluations in horses, records from 134 evaluations performed during a 2-year period were reviewed and the outcome was determined via telephone follow-up interview. Sixty-two percent of the prepurchase evaluations had been performed at the clinic and 38% had been performed in the field by the ambulatory service. All evaluations included physical and lameness examinations, whereas radiography (49%), endoscopy (15%), nerve blocking (5%), transrectal palpation (3%), hematologic analysis (2%), electrocardiography (2%), drug testing for analgesic agents (2...
Daily variability of equine fecal strongyle egg counts.
The Cornell veterinarian    October 1, 1992   Volume 82, Issue 4 453-463 
Warnick LD.Fecal egg counts often are used for diagnosing equine strongyle infections and estimating the number of eggs shed in the feces. An individual egg count should be interpreted in view of the normal fluctuation of egg numbers in an individual horse. In this study, the daily variability of strongyle fecal egg counts from horses was investigated. The Cornell-McMaster egg-counting technique was used to estimate the eggs per gram of feces in repeated daily fecal samples from 39 horses. The variation of the daily egg counts across 4 days was greater than would be expected if a consistent number of egg...
Sarcocystis neurona-associated ataxia in horses in Brazil.
Veterinary parasitology    October 1, 1992   Volume 44, Issue 3-4 311-314 doi: 10.1016/0304-4017(92)90128-v
Masri MD, Alda JL, Dubey JP.Sarcocystis neurona-like schizonts were found in sections of brain and spinal cord of two ataxic horses from Brazil. The diagnosis was supported by staining with anti-Sarcocystis serum in an immunohistochemical test. One of the affected horses was born in Argentina and raised in Brazil, and the other horse was born and raised in Brazil.
Retrospective evaluation of factors associated with the risk of seropositivity to Ehrlichia risticii in horses in New York State.
American journal of veterinary research    October 1, 1992   Volume 53, Issue 10 1931-1934 
Atwill ER, Mohammed HO, Dubovi E, Lopez J.A retrospective study was designed to determine the distribution of equine monocytic ehrlichiosis among the equine population in New York state, and to identify factors associated with risk of disease. Serum samples submitted to the diagnostic laboratory of the university during the period from January 1985 through December 1986 were examined for antibodies to Ehrlichia risticii, using the indirect fluorescent antibody technique. Factors evaluated included geographic origin and date of submission of the sample, and age, breed, and sex of the horse. Logistic regression analysis was used to iden...
Serological evidence of equine herpesvirus type 1 (EHV-1) activity in polo horses in Nigeria.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B    October 1, 1992   Volume 39, Issue 8 628-630 doi: 10.1111/j.1439-0450.1992.tb01214.x
Adeyefa CA.Serological evidence of Equine Herpes virus type 1 (EHV-1) activity in Polo horses in Nigeria is reported for the first time. Eighty-two percent of horses tested with known antigen had precipitating antibodies to EHV-1 while 43% of sera tested against antigen prepared from nasal discharges were positive suggesting that the virus was being excreted in the nasal discharges and probably acting as a source of infection for incontact animals as occurs in on-going acute infections. The result of this study indicates a high prevalence of EHV-1 activity among Polo horses in Nigeria and demonstrates th...
Streptomycin-resistant Escherichia coli as a marker of vulvovestibular contamination of endometrial culture swabs in the mare.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire    October 1, 1992   Volume 56, Issue 4 308-312 
Waelchli RO, Corboz L, Doebeli M.To investigate the vulvovestibular contamination of endometrial culture swabs in the mare, a liquid culture of a streptomycin-resistant strain of Escherichia coli was applied to the vulvovestibular area of mares and used as a marker of contamination of endometrial culture swabs. Prior to taking endometrial swabs, the perineal area was washed with soap, rinsed with water, and dried. Endometrial culture swabs were taken from mares that were in anestrus or diestrus and from mares that were in estrus. When a manual transvaginal swabbing technique was used, 22 of 24 endometrial swab specimens from ...
[Legionella antibodies in domestic animals].
Ceskoslovenska epidemiologie, mikrobiologie, imunologie    October 1, 1992   Volume 41, Issue 5 268-273 
Bazovská S, Awad-Masalmeh M, Kmety E, Spaleková M.Serological examination of 420 domestic animals for the presence of antilegionella antibodies indicates their high exposure to legionellae. On examination by the microagglutination reaction with a serum dilution of 1:64 or more the highest positive values were recorded in horses which reacted with antigens of L. pneumophila 1-14 in 36.2% and with antigens of another 19 types of legionellae in 47.8%. In pigs positive values recorded in 16.2% and in 21.1%; in cattle in 3.8% and 29.5%, in sheep in 7.5% and 11.3% and laboratory rabbits were quite negative. The importance of these findings with reg...
Acholeplasma multilocale sp. nov., isolated from a horse and a rabbit.
International journal of systematic bacteriology    October 1, 1992   Volume 42, Issue 4 513-517 doi: 10.1099/00207713-42-4-513
Hill AC, Polak-Vogelzang AA, Angulo AF.Acholeplasma strains were isolated from the nasopharynx of a horse (strain PN525T [T = type strain]) and the feces of a rabbit (strain B1). One clone of strain PN525T and one clone of strain B1 were examined in detail. These clones were indistinguishable from each other and were serologically distinct from the previously described Acholeplasma and Mycoplasma spp. The strains had the following properties: guanine-plus-cytosine content of 31 mol%; sterol was not required for growth, which occurred under both aerobic and anaerobic conditions; glucose was metabolized; and arginine was hydrolyzed. ...
The development of naturally acquired cyathostome infection in ponies.
Veterinary parasitology    September 1, 1992   Volume 44, Issue 1-2 127-142 doi: 10.1016/0304-4017(92)90151-x
Love S, Duncan JL.Groups of animals of different ages and experience of previous parasite exposure were allowed to graze a single pasture for 5 weeks in autumn (7 October to 11 November). There was evidence that previous exposure modified cyathostome development, as acquired burdens in foals which had previously grazed were smaller and developed more slowly than those of helminth-naive animals of the same age. The burdens acquired by yearling and adult ponies were of a similar size to those of the previously grazed foals, but the incidence of arrested development was higher in the younger groups of foals and ye...
Rapid detection of equine herpesvirus type-1 antigens in nasal swab specimens using an antigen capture enzyme-linked immunosorbent assay.
Journal of virological methods    September 1, 1992   Volume 39, Issue 3 299-310 doi: 10.1016/0166-0934(92)90103-k
Sinclair R, Mumford JA.An antigen capture enzyme-linked immunosorbent assay (ELISA) was developed for the detection of equine herpesvirus type-1 (EHV-1) antigens in nasal swab specimens. The test was designed as a solid phase, amplified sandwich assay in which an EHV-1 specific monoclonal antibody was used to capture virus antigen and polyclonal antisera used to detect antigen bound to the test plates. Eight monoclonal antibodies were tested for their ability to capture virus antigen and one was selected for routine use. The sensitivity and specificity of the ELISA was compared with that of virus isolation using swa...
World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) methods for the detection of anthelmintic resistance in nematodes of veterinary importance.
Veterinary parasitology    September 1, 1992   Volume 44, Issue 1-2 35-44 doi: 10.1016/0304-4017(92)90141-u
Coles GC, Bauer C, Borgsteede FH, Geerts S, Klei TR, Taylor MA, Waller PJ.Methods have been described to assist in the detection of anthelmintic resistance in strongylid nematodes of ruminants, horses and pigs. Two tests are recommended, an in vivo test, the faecal egg count reduction test for use in infected animals, and an in vitro test, the egg hatch test for detection of benzimidazole resistance in nematodes that hatch shortly after embryonation. Anaerobic storage for submission of faecal samples from the field for use in the in vitro test is of value and the procedure is described. The tests should enable comparable data to be obtained in surveys in all parts o...
Genomic variability among globally distributed isolates of equine arteritis virus.
Veterinary microbiology    September 1, 1992   Volume 32, Issue 2 101-115 doi: 10.1016/0378-1135(92)90099-f
Murphy TW, McCollum WH, Timoney PJ, Klingeborn BW, Hyllseth B, Golnik W, Erasmus B.Equine arteritis virus (EAV), a non-arthropod borne togavirus, has been shown to have a global distribution. To date, no major antigenic variation has been demonstrated between EAV isolates from different geographic origins. In this study, the genomic RNA of EAV isolates obtained from horses of different breeds in various countries around the world was oligonucleotide fingerprinted. Comparisons of these fingerprints were used to determine the extent of genomic variation among such isolates. Comparisons among isolates from North American horses revealed, for the most part, oligonucleotide homol...
Serological survey of Rhodococcus equi infection in horses in Hokkaido.
The Journal of veterinary medical science    August 1, 1992   Volume 54, Issue 4 649-652 doi: 10.1292/jvms.54.649
Sanada Y, Noda H, Nagahata H.Serological survey of Rhodococcus equi infection in horses in Hokkaido was performed using ELISA. Of 2,879 horse sera, 318 (11.0%) gave antibody-positive (OD greater than or equal to 0.3) reactions. The antibody-positive rate of female was significantly higher (p less than 0.01) than that of male, and no statistical difference between Anglo-Arab and thoroughbred was detected in the antibody-positive rate. The maximum antibody-positive rate (27.1%) was shown at 14 years of age. The antibody-positive rates on the 160 farms were found to vary widely from 0 to 78.9%. A significant difference (p le...
Detection of African horsesickness virus in infected spleens by a sandwich ELISA using two monoclonal antibodies specific for VP7.
Journal of virological methods    August 1, 1992   Volume 38, Issue 2 229-242 doi: 10.1016/0166-0934(92)90113-r
Laviada MD, Babín M, Dominguez J, Sánchez-Vizcaíno JM.A sandwich enzyme-linked immunsorbent assay (ELISA) for rapid detection of African horsesickness virus (AHSV) in infected spleens or cell culture supernatant was developed. This method uses two monoclonal antibodies (MAbs) which recognize two non-overlapping epitopes of the major core protein (VP7) to coat the solid phase, and one labeled with biotin as second antibody. This ELISA was evaluated for its ability to detect AHSV in infected spleens resulting in a sensitivity of 97.4% and a specificity of 100% compared with virus isolation in cell culture, and can be used for the detection of the n...
Detection of group C rotavirus antigens and antibodies in animals and humans by enzyme-linked immunosorbent assays.
Journal of clinical microbiology    August 1, 1992   Volume 30, Issue 8 2129-2134 doi: 10.1128/jcm.30.8.2129-2134.1992
Tsunemitsu H, Jiang B, Saif LJ.Enzyme-linked immunosorbent assays (ELISAs) were developed to detect group (gp) C rotavirus antigens and antibodies. Both assays were confirmed to be specific for gp C rotavirus by using serogroup A, B, and C rotaviruses; hyperimmune antisera to these serogroups of rotaviruses; and paired serum specimens from animals infected with gp C rotaviruses. The ELISA for antigen detection reacted not only with porcine gp C rotaviruses but also with human and bovine gp C rotaviruses. Following experimental challenge of gnotobiotic pigs with porcine gp C rotavirus, the virus was found by ELISA in all dia...
Validation of a centrifugation/flotation technique for the diagnosis of equine cestodiasis.
The Veterinary record    July 25, 1992   Volume 131, Issue 4 71-72 doi: 10.1136/vr.131.4.71
Proudman CJ, Edwards GB.A centrifugation/flotation technique for the identification of equine tapeworm eggs is described. It was validated by using faeces samples from 80 horses of known tapeworm status, and had a sensitivity of 61 per cent and a specificity of 98 per cent. The exclusion of false negative results in animals with less than 20 tapeworms increased the sensitivity to 92 per cent. No significant correlation was found between the number of eggs observed and the number of tapeworms present in the horses.
Vectors of African horse sickness in the Cape Verde Islands.
The Veterinary record    July 18, 1992   Volume 131, Issue 3 56 doi: 10.1136/vr.131.3.56
Boorman J, van Harten A.No abstract available
Pneumocystis carinii infection in foals in the UK.
The Veterinary record    July 4, 1992   Volume 131, Issue 1 19 doi: 10.1136/vr.131.1.19-a
Whitwell K.No abstract available
Prevalence and serovars of leptospira involved in equine abortions in central Kentucky during the 1990 foaling season. Donahue JM, Smith BJ, Donahoe JK, Rigsby CL, Tramontin RR, Poonacha KB, Wilson MA.A study to determine the prevalence of leptospira-induced abortions in the central Kentucky equine population during the 1990 foaling season and to determine the leptospira serovars responsible was conducted. From July 1, 1989 through June 30, 1990, 32 (4.4%) of 726 submissions (fetuses, stillborn foals, and/or placentas) were diagnosed as leptospirosis by the fluorescent antibody test and/or microscopic agglutination test. Attempts were made to isolate leptospires from the fetal tissues and/or the dam's urine in 31 of these cases. Leptospira interrogans serovar kennewicki was isolated from 11...
The incidence of abnormal limb development in the Irish thoroughbred from birth to 18 months.
Equine veterinary journal    July 1, 1992   Volume 24, Issue 4 305-309 doi: 10.1111/j.2042-3306.1992.tb02841.x
O'Donohue DD, Smith FH, Strickland KL.A two part survey was carried out in Irish Thoroughbred horses in 1988 and 1989 to establish the incidence and prevalence of developmental skeletal problems, particularly possible manifestations of developmental orthopaedic disease (DOD). Survey One was a retrospective study based on a questionnaire involving the foal crops of 46 stud farms for 3 successive seasons; the 1711 animals initially documented represented 10.46% of Irish foal registrations. The second survey involved repeated monitoring of the 1988 foal crop from birth to 18 months of age on 17 stud farms. The 248 foals initially exa...
Use of bacitracin in the prevention and treatment of experimentally-induced idiopathic colitis in horses. Staempfli HR, Prescott JF, Carman RJ, McCutcheon LJ.Ten healthy ponies from a single herd were found by repeated fecal culture to be free of Salmonella species and Clostridium cadaveris. In a preliminary study, four ponies administered a single oral dose of 10 mg/kg lincomycin did not develop idiopathic colitis when the drug was administered alone. Four other ponies were administered 10 mg/kg lincomycin by stomach tube together with 0.45 L of colonic content from a horse with idiopathic colitis induced earlier by lincomycin alone. Two of the four ponies were treated with 25 g oral zinc bacitracin premix (110 g/kg active ingredient) 24 h later. ...
Haematology of experimental babesiosis and ehrlichiosis in steroid immunosuppressed horses.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B    July 1, 1992   Volume 39, Issue 5 345-352 doi: 10.1111/j.1439-0450.1992.tb01179.x
Oladosu LA, Olufemi BE.An investigation was carried out to study the haematology of steroid immunosuppressed horses experimentally infected with Babesia equi and Ehrlichia equi, separately or simultaneously. Horses infected with both pathogens showed less marked changes in their haematology than those inoculated with either pathogen separately. This appeared to result from early elimination of the more pathogenic Babesia as Ehrlichia spread through the granulocytes. The apparent suppression of Babesia by Ehrlichia is of field clinical importance and merits further investigation for its apparent useful potentials in ...
An association between complete and incomplete stress fractures of the humerus in racehorses.
Equine veterinary journal    July 1, 1992   Volume 24, Issue 4 260-263 doi: 10.1111/j.2042-3306.1992.tb02831.x
Stover SM, Johnson BJ, Daft BM, Read DH, Anderson M, Barr BC, Kinde H, Moore J, Stoltz J, Ardans AA.Twenty-one horses had a complete unilateral humeral fracture during race training or racing at a California racetrack during the period 24 February 1990 to 10 July 1991. Fractures occurred approximately equally in left and right limbs, and in males and females. Most fractures occurred during training, and in 2- and 3-year-old horses. Only 5 of 16 Thoroughbred horses with known racing records had previously raced more than once, and their mean time between races was less than the time between their last race and fracture (P = 0.07). Ten of 13 humeri studied further had gross evidence of periost...
The pathogenicity of Ab4p, the sequenced strain of equine herpesvirus-1, in specific pathogen-free foals.
Virology    July 1, 1992   Volume 189, Issue 1 317-319 doi: 10.1016/0042-6822(92)90707-v
Gibson JS, Slater JD, Field HJ.The sequencing of the genome of equine herpesvirus-1 (EHV-1) is reported in Elizabeth A. R. Telford, Moira S. Watson, Kathryn McBride, and Andrew J. Davison, 1992, Virology, 189, 304-316. The sequence was derived using a plaque-purified clone of EHV-1 strain Ab4 (designated Ab4p). To ensure that Ab4p shares the pathogenic characteristics of parental Ab4 (hereafter Ab4), both were inoculated intranasally into foals, specifically free from EHV-1 and EHV-4. Clinical signs, including rectal temperature, were similar for both viruses. In addition, nasal shedding of virus was observed over a 1- to 2...
Effects of alternation of drug classes on the development of oxibendazole resistance in a herd of horses.
Journal of the American Veterinary Medical Association    July 1, 1992   Volume 201, Issue 1 51-55 
Uhlinger C, Kristula M.Anthelmintic schedules that alternate between drug classes are widely used in horses. However, the results of investigations in which ovine nematode parasites were used have established that alternation of drug classes does not delay the development of drug resistance. This field study was designed to assess the effect of alternation of drug classes on the development of oxibendazole (OBZ) resistance in benzimidazole (BZD)-resistant equine small strongyles. A privately owned herd of horses was used for this study. These animals grazed the same pasture and had been treated with the same anthelm...
Lyme borreliosis in cattle and horses: a review of the literature.
The Cornell veterinarian    July 1, 1992   Volume 82, Issue 3 253-274 
Parker JL, White KK.A complete search of the literature concerning Lyme borreliosis as it relates to horses and cattle was done. The epidemiology, pathogenesis, immunological response to the disease, diagnosis and treatment are discussed. A review of clinical cases in horses and cattle is presented. Clinical signs of Lyme borreliosis in horses include: chronic weight loss, sporadic lameness, laminitis, low grade fever, swollen joints, muscle tenderness, and anterior uveitis. In addition to those clinical signs, neurological signs such as depression, behavioral changes, dysphagia, head tilt and encephalitis can be...
The risk of severity of limb injuries in racing thoroughbred horses.
The Cornell veterinarian    July 1, 1992   Volume 82, Issue 3 331-341 
Mohammed HO, Hill T, Lowe J.A retrospective study was carried out to identify factors which predisposed Thoroughbred horses to severe injuries, as compared to less severe injuries, while racing on New York Racing Association (NYRA) tracks during the period of January 1986 to June 1988. A severe injury was defined as an injury which led to humane destruction of the horse. A less severe injury was defined as a horse which didn't race within 6 months following a muscular, ligament, tendon, or skeletal injury on the racetrack. The data were obtained from the Horse Identification Department records kept by the Chief Examining...
A review of African horse sickness with emphasis on selected vaccines.
Annals of the New York Academy of Sciences    June 16, 1992   Volume 653 228-232 doi: 10.1111/j.1749-6632.1992.tb19651.x
House C, House JA, Mebus CA.No abstract available
Venezuelan equine encephalomyelitis and African horse sickness. Current status and review.
Annals of the New York Academy of Sciences    June 16, 1992   Volume 653 217-227 doi: 10.1111/j.1749-6632.1992.tb19650.x
Walton TE, Holbrook FR, Bolivar-Raya R, Ferrer-Romero J, Ortega MD.The arthropod-borne virus (arbovirus) diseases of livestock have worldwide impact. The prevention of an introduction of an exotic disease and the control of one subsequent to an introduction will require the attention, cooperation, and support of the livestock industry, regulatory agencies, and researchers. The most effective protection of our livestock industries is to prevent the introduction of an exotic disease agent. This implies complete restriction of animal imports and exports. However, "zero risk" is an unacceptable option in today's world of internationally integrated and interdepend...
Restriction enzyme maps for equine adenovirus 1 genome.
Veterinary microbiology    June 15, 1992   Volume 31, Issue 4 343-349 doi: 10.1016/0378-1135(92)90126-e
Sheppard M, Drysdale SM, Studdert MJ.Physical maps were constructed for the genome of equine adenovirus 1 (EAV1) using the restriction enzymes; DraI, EcoRV, NotI and SfiI. The total size of the EAV1 genome was 34.4 kb estimated by comparison with known DNA standards and the polarity of the fragment order, with respect to the left and right molecular ends, was determined by hybridization with known regions of the human adenovirus 2 (HAV2) genome.