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Topic:Infection

Infections in horses encompass a range of diseases caused by various pathogens, including bacteria, viruses, fungi, and parasites. These infections can affect different systems within the horse, such as the respiratory, gastrointestinal, and integumentary systems, leading to a variety of clinical signs depending on the pathogen and the severity of the infection. Common infectious diseases in horses include equine influenza, strangles, and equine herpesvirus. Diagnosis often involves clinical examination, laboratory testing, and sometimes imaging, to identify the causative agent and assess the extent of the disease. Treatment strategies may include antimicrobial therapy, supportive care, and preventive measures such as vaccination and biosecurity practices. This page aggregates peer-reviewed research studies and scholarly articles that explore the pathogenesis, diagnosis, treatment, and prevention of infectious diseases in equine populations.
Equine protozoal myeloencephalitis.
The Veterinary clinics of North America. Equine practice    August 1, 1987   Volume 3, Issue 2 397-403 doi: 10.1016/s0749-0739(17)30682-x
Madigan JE, Higgins RJ.Equine protozoal myeloencephalitis (EPM) is a disease that produces neurologic signs of brain or spinal cord dysfunction. The causative organism is believed to be a Sarcocystis species of protozoa. A definitive diagnosis can only be made on histopathology of affected spinal cord or brain. No preventive measures or documented treatment is available at this time for suspected cases of EPM.
A review of the pharmacology and clinical uses of ivermectin.
The Canadian veterinary journal = La revue veterinaire canadienne    August 1, 1987   Volume 28, Issue 8 512-517 
Barragry TB.The avermectins were introduced in 1981 and constitute a potent new class of anthelmintic agents. They are naturally-derived products of microbial action displaying an exceptionally wide range of antiparasitic efficacy against internal and external parasites of domestic animals. This paper reviews their isolation and chemistry, mechanism of action, chemical efficacy and safety in cattle, sheep, swine, horses and dogs.
The immunological response of foals to Rhodococcus equi: a review.
Veterinary microbiology    August 1, 1987   Volume 14, Issue 3 215-224 doi: 10.1016/0378-1135(87)90108-8
Woolcock JB, Mutimer MD, Bowles PM.Normal horses of all ages regularly show evidence of having responded immunologically to R. equi, thus adding serological support to epidemiological evidence that this organism is a normal intestinal inhabitant. More animals from "diseased" farms show a stronger antibody response when compared with foals from "healthy" farms. Various serological tests have been used to detect evidence of infection and to relate antibody level to severity of disease. Anti-R. equi IgG antibody levels, as measured by ELISA, are raised significantly during natural infection. Clinical severity of pneumonia can be c...
Interaction of Rhodococcus equi with phagocytic cells from R. equi-exposed and non-exposed foals.
Veterinary microbiology    August 1, 1987   Volume 14, Issue 3 307-320 doi: 10.1016/0378-1135(87)90118-0
Hietala SK, Ardans AA.The interaction of Rhodococcus equi with alveolar macrophages from adult horses, foals experimentally exposed to R. equi (sensitized foals) and non-exposed foals was studied using in vitro bactericidal assays, cytochemical staining and transmission electron microscopy. It was demonstrated that R. equi is a facultative intracellular parasite, able to survive and multiply within the alveolar macrophages of the host by interfering with phagosome-lysosome fusion. Opsonization of R. equi with antibody against capsular components was associated with increased phagosome-lysosome fusion and significan...
Humoral immune response of foals to experimental infection with Rhodococcus equi.
Veterinary microbiology    August 1, 1987   Volume 14, Issue 3 321-327 doi: 10.1016/0378-1135(87)90119-2
Takai S, Kawazu S, Tsubaki S.Humoral immune response to Rhodococcus equi in experimentally infected foals was studied with the enzyme-linked immunosorbent assay (ELISA) method. Class-specific antibodies were measured by ELISA in the sera of foals after intratracheal or oral inoculation with R. equi ATCC 6939 or T 48 and in the lung washings of a foal after intratracheal inoculation or of normal horses. After intratracheal or oral inoculation with R. equi, serum antibodies were first detected in immunoglobulin G (IgG) followed by IgM and IgA classes, but significant levels of IgM and IgA developed only in the foal infected...
Ovarian disorders in domestic animals.
Environmental health perspectives    August 1, 1987   Volume 73 27-33 doi: 10.1289/ehp.877327
MacLachlan NJ.The histologic appearance of the ovaries and persistence of corpora lutea vary considerably among domestic animals, particularly between spontaneous and induced ovulators. The seasonally polyestrous mare has a variety of unique characteristics in ovarian structure and general reproductive function. Among the anomalies of ovarian development is the bovine freemartin with gonads containing a mixture of male and female elements. A variety of ovarian cysts occur in domestic animals, and persistent corpora lutea with associated reproductive perturbations occur in several species. Ovarian tumors are...
Rhodococcus equi: equine neutrophil chemiluminescent and bactericidal responses to opsonizing antibody.
Veterinary microbiology    August 1, 1987   Volume 14, Issue 3 277-286 doi: 10.1016/0378-1135(87)90115-5
Martens RJ, Martens JG, Renshaw HW, Hietala SK.The opsonic capacity of serum containing R. equi-specific antibody was compared with antibody-deficient sera using luminol-dependent chemilumenscence (LDCL) and bactericidal assays. These assays incorporated peripheral blood polymorphonuclear neutrophilic leukocytes (PMNL) exposed to R. equi opsonized with neonatal equine pre-colostral serum (control) or serum from foals with R. equi infections (principal). All sera were complement inactivated at 56 degrees C for 30 min. Bacteria were obtained from the lung of a foal with R. equi pneumonia. Neutrophils were obtained from one adult horse for LD...
Epidemiology of Rhodococcus equi infection in horses.
Veterinary microbiology    August 1, 1987   Volume 14, Issue 3 211-214 doi: 10.1016/0378-1135(87)90107-6
Prescott JF.Current understanding of the epidemiology of Rhodococcus equi infection on horse farms is reviewed. Infection is widespread in herbivores and their environment, because herbivore manure supplies the simple organic acid substrates on which the organism thrives. There is a progressive development of infection in the soil on horse farms with prolonged use, because: (1) there is a continual supply of nutrients; (2) the organism multiplies progressively as temperatures rise; (3) the bacterium has a robust nature. While this aerobic organism fails to multiply in the largely anaerobic intestine of th...
Dynamics of equi-factor antibodies in sera of foals kept on farms with differing histories of Rhodococcus equi pneumonia.
Veterinary microbiology    August 1, 1987   Volume 14, Issue 3 269-276 doi: 10.1016/0378-1135(87)90114-3
Skalka B.The occurrence of equi-factor antibodies in sera of mares and their foals was studied on two horse breeding farms, one of which (Farm A) had a positive and the other (farm B) a negative history of R. equi infection of foals. The equi-factor neutralization (EFN) and the reverse Elek-Ouchterlony (REO) precipitation were used as assays. On Farm A, 25 mares positive in both tests (EFN+ REO+) and 25 mares negative in both tests (EFN- REO-) was chosen. On Farm B, a group of 25 EFN- REO+ mares and a group of 25 EFN- REO- mares were studied. The first serum samplings in mares were 1 week ante partum a...
Use of an external skeletal fixation device and bone graft for arthrodesis of the metacarpophalangeal joint in horses.
Journal of the American Veterinary Medical Association    August 1, 1987   Volume 191, Issue 3 316-321 
Richardson DW, Nunamaker DM, Sigafoos RD.Arthrodesis of the metacarpophalangeal joint was attempted in 9 adult horses, using a new external skeletal fixation device and autogenous cancellous bone graft. Four horses had excellent results, 2 horses had fair results, arthrodesis failed in 2 horses, and 1 horse fractured the third metacarpal bone. The advantages of the technique included minimal surgical trauma to the area of injury, immediate rigid fixation of the metacarpophalangeal joint, and access for treatment of soft-tissue lesions at the site of injury. Although pin loosening and pin-track infection were complications when the de...
Equine herpes myeloencephalopathy.
The Veterinary clinics of North America. Equine practice    August 1, 1987   Volume 3, Issue 2 405-419 doi: 10.1016/s0749-0739(17)30683-1
Kohn CW, Fenner WR.The neurologic form of EHV-1 infection appears to be the result of central nervous system infarction caused by vasculitis, which is initiated in endothelial cells of small blood vessels. The etiologic agent is equine herpesvirus-1, subtype 1. There is some evidence to suggest that the neurologic form of the disease actually results from reactivation of a previous infection. Whether the vasculitis that causes the central nervous system injury is the direct result of the infection or an immune response to the infection has not been determined. The clinical signs are rapid in onset, nonprogressiv...
Rhodococcus equi in fecal and environmental samples from Kansas horse farms.
Veterinary microbiology    August 1, 1987   Volume 14, Issue 3 251-257 doi: 10.1016/0378-1135(87)90112-x
Debey MC, Bailie WE.Horse farms in Kansas were surveyed for the incidence of Rhodococcus equi. Fecal specimens and soil or cobweb samples were collected from each farm and cultured on selective media. One control farm (with no history of R. equi infection), one farm which had an outbreak 3 and 4 years previously and 2 farms which had R. equi-infected foals that season were surveyed. In addition, fecal samples from 21 horses hospitalized in the Kansas State University Veterinary Hospital were cultured. There was no significant difference in the incidence of R. equi in fecal samples from the 2 farms with recent dis...
Ecology of Rhodococcus equi in horses and their environment on horse-breeding farms.
Veterinary microbiology    August 1, 1987   Volume 14, Issue 3 233-239 doi: 10.1016/0378-1135(87)90110-6
Takai S, Fujimori T, Katsuzaki K, Tsubaki S.Quantitative culture of R. equi in the feces of dams and foals, in the air of the stalls and in the soil of the paddocks was carried out on three horse-breeding farms during the foaling season. The isolation rates of R. equi from the feces of dams from the 3 farms suddenly increased to approximately 80% at the end of March, when the snow in the paddocks finished melting, and remained at that level during April and May. The mean number of R. equi and the isolation rate of R. equi from the feces of dams on the farms were investigated for 5 weeks before and 5 weeks after delivery. During the 10 w...
The pathogenesis of Rhodococcus equi pneumonia in foals.
Veterinary microbiology    August 1, 1987   Volume 14, Issue 3 225-232 doi: 10.1016/0378-1135(87)90109-x
Yager JA.The pathogenesis of Rhodococcus equi pneumonia in foals is reviewed. The main routes of infection are respiratory and alimentary. The latter is probably the chief route of exposure in all foals and probably leads to development of specific immunity. Susceptible foals, those whose maternal immunity wanes before generation of their own immune response, readily develop disease if exposed aerogenously to sufficient numbers of R. equi. Management and environmental circumstances have a major role to play in determining the magnitude of this challenge and, therefore, in the prevalence of the disease....
Balloon-tipped catheter arterial occlusion for prevention of hemorrhage caused by guttural pouch mycosis: 13 cases (1982-1985).
Journal of the American Veterinary Medical Association    August 1, 1987   Volume 191, Issue 3 345-349 
Caron JP, Fretz PB, Bailey JV, Barber SM, Hurtig MB.Epistaxis, caused by guttural pouch mycosis, was treated by balloon-tipped catheter and ligature occlusion of the involved arteries in 13 horses. In 7 horses, more than one artery was catheterized. Serious postoperative hemorrhage was prevented in all horses. Long-term endoscopic follow-up examination was possible in 8 horses, and all had complete regression of the fungal lesion as early as 5 weeks after surgery. Six of the 8 horses did not receive medical treatment. Problems related to the use of the balloon-tipped catheter technique were rare. There were incisional infections in 3 horses, ca...
Urethral pressure profilometry in mares.
Journal of the American Veterinary Medical Association    July 15, 1987   Volume 191, Issue 2 212-216 
Kay AD, Lavoie JP.A technique was developed for recording urethral pressure profiles (UPP) in mares. Profiles were obtained from 12 clinically normal mares and from 3 mares with urinary incontinence. Variables measured on the profile included intravesicular pressure and maximal urethral closure pressure. The mean maximal urethral closure pressure of the incontinent mares was significantly less (P less than or equal to 0.001) than that of the normal mares. The technique is simple and reliable for objectively evaluating urethral pressures in mares.
Marsupialization of an abdominal abscess caused by Serratia marcescens in a mare.
Journal of the American Veterinary Medical Association    July 15, 1987   Volume 191, Issue 2 222-224 
Rigg DL, Gatlin SJ, Reinertson EL.An intra-abdominal abscess was diagnosed in a 7-year-old mare by palpation per rectum and from abnormal clinicopathologic findings. Initial treatment with procaine penicillin for 21 days was unsuccessful in halting the deterioration of the physical condition of the mare. Surgical exploration of the abdomen revealed a mass in the wall of the left ventral colon. Drainage was achieved by marsupialization. Serratia marcescens was isolated from the abscess. Recovery appeared complete, and the mare has resumed broodmare capability.
The binding domain on horse cytochrome c and Rhodobacter sphaeroides cytochrome c2 for the Rhodobacter sphaeroides cytochrome bc1 complex.
Biochemistry    July 14, 1987   Volume 26, Issue 14 4501-4504 doi: 10.1021/bi00388a049
Hall J, Zha XH, Yu L, Yu CA, Millett F.The interaction of the Rhodobacter sphaeroides cytochrome bc1 complex with Rb. sphaeroides cytochrome c2 and horse cytochrome c was studied by using specific lysine modification and ionic strength dependence methods. The rate of the reactions with both cytochrome c and cytochrome c2 decreased rapidly with increasing ionic strength above 0.2 M NaCl. The ionic strength dependence suggested that electrostatic interactions were equally important to the reactions of the two cytochromes, even though they have opposite net charges at pH 7.0. In order to define the interaction domain on horse cytochro...
Laminitis and possible enterotoxaemia associated with carbohydrate overload in mares.
Equine veterinary journal    July 1, 1987   Volume 19, Issue 4 344-346 doi: 10.1111/j.2042-3306.1987.tb01430.x
Carroll CL, Hazard G, Coloe PJ, Hooper PT.No abstract available
Cutaneous leishmaniasis in a horse (Equus caballus) from endemic area in the state of Espirito Santo, Brazil.
Memorias do Instituto Oswaldo Cruz    July 1, 1987   Volume 82, Issue 3 443 doi: 10.1590/s0074-02761987000300020
Falqueto A, Varejão JB, Sessa PA.No abstract available
[Sarcocystis and chronic myopathies in horses].
Berliner und Munchener tierarztliche Wochenschrift    July 1, 1987   Volume 100, Issue 7 229-232 
Fransen JL, Degryse AD, Van Mol KA, Ooms LA.No abstract available
Anaerobic bacteria associated with dental abscesses in the horse and donkey.
Equine veterinary journal    July 1, 1987   Volume 19, Issue 4 360-362 doi: 10.1111/j.2042-3306.1987.tb01435.x
Mackintosh ME, Colles CM.No abstract available
Isolation of Clostridium difficile and detection of cytotoxin in the feces of diarrheic foals in the absence of antimicrobial treatment.
Journal of clinical microbiology    July 1, 1987   Volume 25, Issue 7 1225-1227 doi: 10.1128/jcm.25.7.1225-1227.1987
Jones RL, Adney WS, Shideler RK.Clostridium difficile was isolated from the feces of 27 of 43 diarrheic foals (63%), and cytotoxin was detected in feces from 28 diarrheic foals (65%). The foals had not received any antimicrobial treatment before the onset of diarrhea. C. difficile was not isolated from feces of 18 normal foals without diarrhea and 62 adult horses (P less than 0.005). This finding of C. difficile and its toxins in association with diarrhea in foals adds another possible cause to the list of infectious agents which may cause diarrhea in foals.
[Ecological characteristics of horse stomach botflies in Uzbekistan].
Parazitologiia    July 1, 1987   Volume 21, Issue 4 577-579 
Enileeva NKh.The paper describes the flight periods and dynamics of abundance of horse botflies, life span of females and males, effect of environmental factors on the activity of flies and their behaviour, potential fecundity of different species of botflies, duration of embryonal development, preservation of viability of larvae in egg membranes, localization of different stages of botflies in the host, and methods of their control.
Total parenteral nutritional therapy of a foal with diarrhoea from which parvovirus-like particles were identified.
Equine veterinary journal    July 1, 1987   Volume 19, Issue 4 342-344 doi: 10.1111/j.2042-3306.1987.tb01429.x
Baker JC, Ames TR.No abstract available
Klebsiella oxytoca Septicemia due to Intravenous Administration of a Contaminated Amino-acid Solution to Three Horses.
The Canadian veterinary journal = La revue veterinaire canadienne    July 1, 1987   Volume 28, Issue 7 422-424 
Hazlett MJ, Goodrow DC, Lynch JA, Kierstead MK.No abstract available
Names and codes of the diseases and clinical signs of dogs, cats, horses, cattle, sheep, goats and swine from the consultant diagnostic database.
The Cornell veterinarian    July 1, 1987   Volume 77, Issue 3 3-165 
White ME.A complete listing of the clinical signs and diseases of dogs, cats, horses, cattle, sheep, goats and swine in the CONSULTANT database for computer assisted diagnosis is presented, along with the codes used to record this data. This list may be useful to those teaching, researching or writing on the diseases of domestic animals, and is of particular use to those who need such a resource for developing diagnostic coding and computer-assisted information retrieval.
Serological Evidence of Coxiella burnetii Infection in Horses in Atlantic Canada.
The Canadian veterinary journal = La revue veterinaire canadienne    July 1, 1987   Volume 28, Issue 7 425-426 
George J, Marrie TJ.No abstract available
Actinobacillus suis-like organisms in horses.
American journal of veterinary research    July 1, 1987   Volume 48, Issue 7 1036-1038 
Jang SS, Biberstein EL, Hirsh DC.Actinobacillus suis-like organisms have been recognized in equine specimens at the University of California Veterinary Medical Teaching Hospital since 1975. The most common source (65%) of the organism was transtracheal washings. The organism was gram-negative, produced hemolysis on blood agar, and gave a positive reaction for oxidase, urease, o-nitrophenyl-beta-D-galactopyranoside, and esculin. Carbohydrate reactions were variable, consisting of 4 main patterns. Actinobacillus suis-like organisms were (90%) sensitive to therapeutic concentrations of amikacin, cephalothin, chloramphenicol, gen...
Equine linkage group II: phase conservation of To with AlB and GcS.
The Journal of heredity    July 1, 1987   Volume 78, Issue 4 248-250 doi: 10.1093/oxfordjournals.jhered.a110376
Bowling AT.Blood type analysis of 29 foals in a paternal half-sib family verified linkage of five LGII loci (Es, E, To, Gc, Al). Population and parentage data from other tobiano-spotted horses suggested conservation of a tightly linked (To:GcS:AlB) marker complex.