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Topic:Infectious Disease
Infectious diseases in horses encompass a range of illnesses caused by bacteria, viruses, fungi, or parasites. These diseases can affect various systems within the equine body, leading to symptoms that range from mild discomfort to severe systemic illness. Common infectious diseases in horses include equine influenza, strangles, equine herpesvirus, and West Nile virus. These diseases can be transmitted through direct contact with infected animals, contaminated surfaces, or vectors such as insects. Understanding the mechanisms of transmission, pathogenesis, and immune response is essential for effective prevention and control. This page compiles peer-reviewed research studies and scholarly articles that explore the epidemiology, diagnosis, treatment, and management of infectious diseases in horses.
Serological study of an outbreak of paresis due to equid herpesvirus 1 (EHV-1). Six cases of paresis occurred in a Swedish stud with 48 mares and a stallion. Complement-fixation tests revealed a recent infection with EHV-1 in most horses of the stud. Serumneutralisation tests showed rapid antibody-titre increases during the course of the disease. This type of antibody response was interpreted as induced by reinfection or, possibly, recurrent infection. Two diseased mares were sacrificed. No virus could be isolated from their central nervous system (CNS), liver or spleen, but there is a presumptive evidence for the presence of an antigen specific to EHV-1 in the CNS and li...
Search for persistent epizootic Venezuelan encephalitis virus in Guatemala, El Salvador and Nicaragua during 1970-1975. Evidence was sought during 1970-1975 of persistence of equine-virulent Venezuelan encephalitis (VE) virus in regions of Central America that were heavily involved in the epidemic-equine epizootic of 1969. (a) Four sentinel horses were exposed in an arid, upland region of the Atlantic drainage of Guatemala during August-October 1970, but no horse became infected. (b) The epicenter region of the 1969 outbreak, in southwestern Guatemala and southwestern El Salvador, was studied during July 1970-February 1974; no antibody developed in sentinel horses, sentinel hamsters did not die, mosquitoes yiel...
Four cases of Tyzzer’s disease in foals in England. A rodent pathogen, Bacillus piliformis, has been recognised as causing a rapidly fatal hepatitis in 4 foals in England. The disease in foals has been recognised in America since 1973. A clinico-pathological account of the 4 cases is given and the differential diagnosis discussed. The 4 foals' ages fell within a very narrow range (24-34 days). Some of the properties of this unusual intracellular pathogen are reviewed. For the first time in the equine the bacillus was seen in association with myocardial lesions. There are marked differences in the epidemiology of the disease in the mouse and in ...
Efficacy of Japanese encephalitis vaccine in horses. The efficacy of Japanese encephalitis vaccine in horses has been described from the effect of mass vaccination on the local prevalence of the disease in horses in each district of Hokkaido, Japan.
A practical health programme for prevention of parasitic and infectious diseases in horses and ponies. A scheme of combined anthelmintic treatment and vaccination is described. The seasonal veterinary activities are as follows: March (all horses); parasitological examination of faeces, anthelmintic treatment, immunization against influenza and tetanus (booster dose). June: parasitological faeces examination of foals, anthelmintic treatment of all horses, immunization of foals against tetanus (1st dose). August: anthelmintic treatment of all horses and immunization of foals against influenza (1st dose) and tetanus (2nd dose). October: parasitological faeces examination and anthelmintic treatment...
A comparison of horse, cow, and sheep blood in NYC medium: effect on recovery of N. gonorrhoeae and urogenital mycoplasmas. NYC medium supplemented with cow blood (NYC-C) and sheep blood (NYC-S) were tested for the growth of N. gonorrhoeae and urogenital mycoplasma in comparison with standard NYC medium which contains horse blood. In situations where horse blood is not available, cow blood could be substituted in NYC standard medium, whereas the use of sheep blood was found unsuitable.
Experience of the efficacy of equine influenza vaccinations. In 1974, a very extensive influenza/A/equi 2 epidemic broke out in the Finnish horse population. To study the efficacy of influenza vaccinations a questionnaire was sent after the epidemic to all Finnish veterinarians. The answer material was selected to contain only stables which had had clinically typical cases. The material consisted 234 unvaccinated and 629 vaccinated horses. In the latter group 466 horses were vaccinated adequately. The results of the study showed that of the unvaccinated horses 212 (91%) and of the adequately vaccinated horses only 42 (9.4%) contracted clinically typical...
[FAB immunoglobulin fragments. I. The comparative characteristics of the serological and virus-neutralizing properties of a gamma globulin against tick-borne encephalitis and of the FAB fragments isolated from it]. A comparative study was made of the serological properties and virus-neutralizing activity of antiencephalitis gamma-globulin and Fab-fragments isolated from it by gel-filtration. Horse immunoglobulins against the autumno-summer tick-borne encephalitis virus could be disintegrated with the aid of papaine to monovalent Fab-fragments which (according to the complement fixation reaction, the test of suppression of the complement fixation, and the HAIT) retained the serological activity whose level was compared with that of the serological activity of gamma-globulin. Fab-fragments possessed a mark...
Search for epizootic-like Venezuelan encephalitis virus at enzootic habitats in Guatemala during 1969-1971. Seventy-four strains of Venezuelan encephalitis (VE) virus recovered from sentinel hamsters or mosquitoes at enzootic habitats in Guatemala in the two years following the 1969 epidemic-equine epizootic were examined for ability to produce small plaques in Vero African green monkey kidney cell cultures, like isolates obtained during the epizootic. (a) One strain recovered from a sentinel hamster in late October 1969 at an enzootic habitat near the epicenter of the hemagglutination-inhibition (HI) and equine-virulence properties like epizootic virus; this strain retained its small plaque charact...
Serological studies and isolations of serotype hardjo and Leptospira biflexa strains from horses of Argentina. Three pathogenic leptosipras and 12 saprophytic Leptospira biflexa strains were isolated from 72 apparently normal horse kidneys collected at an abattoir in Argentina. Cross-agglutination reaction patterns of the pathogens showed that they were antigenically homologous with members of the Hebdomadis group. When one of the strains was compared to Hebdomadis serotypes in reciprocal agglutination-absorption tests, it was found to be serologically homologous to serotype hardjo. This is the first known report of an isolation of this serotype from horses. Serological tests were also carried out on r...
Observations on the transmission, immunology, clinical signs and chemotherapy of dourine (Trypanosoma equiperdum infection) in horses, with special reference to cerebro-spinal fluid. This paper is a record of observations on the transmission and clinical signs of dourine in naturally infected cases of known duration, and of temporal and quantitative aspects of the immune response in blood and cerebro-spinal fluid. Included in the record are observations on the presence of Trypanosoma equiperdum parasites in these body fluids and methods for their detection. There is evidence that the occurrence of nervous symptoms and lesions in infected horses is associated with the presence of Trypanosoma equiperdum parasites in cerebro-spinal fluid. The suitability of cerebro-spinal flu...
Arbovirus surveillance in six states during 1972. A virus surveillance project was established and maintained during 1972 along 10 major river drainages in six states. Mosquitoes, biting flies, and blood specimens from sentinel equines were collected during 83 field trip visits to 141 arthropod collecting sites and 22 sentinel locations from April into December 1972. There were 173,074 mosquitoes tested and 303 arboviruses isolated from 11 of 41 species. From 13,388 biting flies tested, 8 arbovirus isolations were obtained in 1 of 5 species. There was no isolation of Venezuelan equine encephalitis (VEE) virus. Western equine encephalitis (WEE...
An anaemic state in a horse associated with a cold-acting antibody. Auto-immune, haemolytic anacmias (AHA) of man (Dacie, Citation1963) and domestiicated animals (Schalm, Citation1965; Farrelly et al., Citation1966; Lapras and Oudar, Citation1971) are classified either as idiopathic or secondary to an underlying disease process (Pirofsky, Citation1969). In both categories antibodies active against the indivual's own erythrocytes are formed. These auto-antibodies are of two types being either warm or cold-acting. Warm-acting antibodies are most effective at 37°C, belong to the IgG class of immunoglobulins, and are incomplete in that, generally, they do not cau...
Equine herpesviruses. 6. Sequential infection of horses with types 2, 3 and 1. The immunological and virological status of 3 foals in respect of equine herpesviruses (EHV) was established and the foals were sequentially infected with EHV2, EHV3 and EHV1. Following experimental infection with EHV2, no clinical signs of disease were observed in any foal. The inoculation of EHV3 into the genital tract resulted in lesions of the mucous membrane and perineal skin that were considered typical of equine coital exanthema. Following intransal inoculation of EHV3 extensive ulceration and pustule formation on the nasal mucosa was observed by day 5 accompanied at day 7 by a profuse,...
Immunity to equine herpesvirus type 1 (rhinopneumonitis): in vitro lymphocyte response. Twenty-two ponies were examined for serum-neutralizing (SN) antibody to equine herpesvirus type 1 and for in vitro lymphocyte transformation in the presence of viral antigen. Six ponies had undetectable levels of neutralizing antibody (titer less than 1:2) and had lymphocytes which did not respond in culture with viral antigen (stimulation index less than 2.0). Four ponies which had SN antibody to equine herpesvirus type 1 did not manifest lymphocyte transformation in vitro. The 12 remaining seropositive ponies had lymphocyte transformation with viral antigen in vitro (stimulation indexes from...
