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Topic:Veterinary Research

Veterinary research in horses encompasses the study of diseases, health management, and medical treatments specific to equine species. This field investigates various aspects of horse health, including infectious diseases, metabolic disorders, and musculoskeletal conditions. Researchers focus on understanding the pathophysiology of equine ailments, developing diagnostic tools, and evaluating therapeutic interventions. The study of horse health also involves examining preventive measures such as vaccination protocols and nutritional management to promote overall well-being. This page collects peer-reviewed research studies and scholarly articles that explore the diverse areas of veterinary science related to horses, providing insights into disease mechanisms, treatment strategies, and advancements in equine healthcare.
Prevalence of Surra among camels and horses in Jordan.
Preventive veterinary medicine    March 19, 1999   Volume 38, Issue 4 289-293 doi: 10.1016/s0167-5877(98)00138-x
Abo-Shehada MN, Anshassi H, Mustafa G, Amr Z.The prevalence of Trypanosoma evansi infection among camels and horses in Jordan was studied using thick blood smears and inoculation techniques with mice and rats. A total of 437 camels and 83 horses from four climatic zones were surveyed. In addition, 40 donkeys, 32 cattle and 35 goats in contact with infected camels and horses were also tested in the same way. Clinical disease was evident in 8.2% of the camels (36 out of 437) and in 9.6% of the horses (8 out of 83). Infection was limited only to the Sweama area on the Dead Sea (within the warm desert-climatic zone), with prevalence of 30.5%...
The effect of motilin on the regulation mechanism of intestinal motility in conscious horses.
The Journal of veterinary medical science    March 19, 1999   Volume 61, Issue 2 167-170 doi: 10.1292/jvms.61.167
Sasaki N, Yoshihara T.Laparotomy was performed on seven thoroughbreds to attach a force transducer to the proximal jejunum, distal jejunum, and ileum, as well as to the serous membrane of the cecum. Following observation of intestinal motility in conscious horses, they were intravenously injected with motilin (0.6 microgram/kg) to examine its effect on intestinal motility. Strong contractions peculiar to horses were observed in small intestine. Further, motilin caused strong contractions in the proximal jejunum. The results suggested the involvement of motilin in the regulation mechanism of intestinal motility.
Magnetic resonance imaging and ultrasonography of the lumbricale muscles in the horse.
Australian veterinary journal    March 17, 1999   Volume 77, Issue 2 82-84 doi: 10.1111/j.1751-0813.1999.tb11671.x
Bindeus T, Rand T, Alton K, Imhof H, Stanek C.No abstract available
A longitudinal study of racing thoroughbreds: performance during the first years of racing.
Australian veterinary journal    March 17, 1999   Volume 77, Issue 2 105-112 doi: 10.1111/j.1751-0813.1999.tb11678.x
More SJ.To develop a profile of the racing careers of Thoroughbred horses in south-eastern Queensland, and to examine factors that affect racing during the first years of racing. Methods: A longitudinal study using the racing records of a defined cohort of Thoroughbred horses that were born on or within 12 months following 1 August 1991. Data collection commenced in 1996 and will continue until all horses cease racing. In this paper two measures of performance were examined: race earnings during the first year of racing and cumulative proportion of horses still racing up to 2 years after their first s...
[Effect of the administration of PGF2 alpha synchronously with insemination on the pregnancy rate in mares in an insemination program].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    March 17, 1999   Volume 27, Issue 1 54-60 
Bader H, Röhrsheim C, Koene M, Meinecke B.Investigations in different species including the horse have demonstrated that prostaglandin F2 alpha (PGF2 alpha) is involved in initiating uterine contractions occurring during mating and artificial insemination (A.I.). Uterine contractions play an important role with respect to the sperm transport within the female genital tract. The objective of the present investigation was to evaluate whether the administration of PGF2 alpha (Dinoprost) synchronously to A.I. could have a positive effect on the pregnancy rate in mares. A field study including 346 warmblood-mares (age two to 20 years) belo...
[Follicular dynamics after treatment with hCG for ovulation induction in mares].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    March 17, 1999   Volume 27, Issue 1 47-51 
Bollwein H, Braun J.In this study the use of hCG for induction of ovulation is described. Factors such as follicle diameter at the time of administration of hCG (3000 IE hCG i.v.), follicular growth after hCG and the rate of double ovulations were evaluated. A total of 168 mares presented for artificial insemination were used. In 249 estrous periods hCG was given to mares exhibiting standing estrous when a minimum follicle diameter of 30 mm and a well developed edema of the endometrium could be detected by ultrasonography. In nine estrous periods ovulation occurred within 24 hours after hCG. The majority of mares...
Arterially perfused eye model of uveitis.
Australian veterinary journal    March 17, 1999   Volume 77, Issue 2 100-104 doi: 10.1111/j.1751-0813.1999.tb11677.x
Shiels IA, Sanderson SD, Taylor SM.To develop an in vitro model of uveitis based on an ex situ perfused eye to evaluate the anti-inflammatory activity of new pharmacological products. Methods: Eyes were removed from more than 60 dogs and 9 horses immediately after euthanasia and perfused with nutrient medium through the lateral long ciliary artery. Perfused eyes produced aqueous humour, and perfusion pressure was adjusted to obtain an intraocular pressure in the physiological range. When the eyes were treated with histamine, a complement C5a analogue peptide and hydrogen peroxide, typical signs of uveitis were produced. These i...
Description and morphometric analysis of the eggs of Anopheles (Anopheles) vestitipennis (Diptera: Culcidae) from southern Mexico.
Journal of medical entomology    March 11, 1999   Volume 36, Issue 1 78-87 doi: 10.1093/jmedent/36.1.78
Rodriguez MH, Chavez B, Hernandez-Avila JE, Orozco A, Arredondo-Jimenez JI.Light and scanning electron microscopy were used to compare the eggs of Anopheles vestitipennis Dyar & Knab females collected from human and animal baits in 9 villages of southern Mexico. An. vestitipennis eggs are boat-shaped, with lateral floats extending the length of the egg. Both the deck and dorsal surface are covered with hexagonal and pentagonal chorionic cells that contain round tubercles in the cell field. Crowns that enclose 3-5 lobed tubercles are present at both egg poles. By light microscopy, the mean length/width ratio of eggs of females caught at human bait were statistical...
Occurrence of prostasome-like membrane vesicles in equine seminal plasma.
Journal of reproduction and fertility    March 10, 1999   Volume 114, Issue 2 237-243 doi: 10.1530/jrf.0.1140237
Minelli A, Moroni M, Martínez E, Mezzasoma I, Ronquist G.Equine seminal plasma was shown to contain membrane vesicles that are similar to the well characterized prostasomes in human seminal plasma. Determination of nucleoside and nucleotide concentrations of these particles have shown that ATP, ADP and adenosine are the main components of the nucleotidic pool. 5' nucleotidase, endopeptidase and dipeptidyl peptidase i.v. activities have been found on the surface of the particles. The interaction between these prostasome-like vesicles and spermatozoa was demonstrated by electron micrograph scans which revealed the steps of a fusion-like process leadin...
Postanaesthetic recumbency in a Belgian filly with polysaccharide storage myopathy.
The Veterinary record    March 10, 1999   Volume 144, Issue 3 73-75 doi: 10.1136/vr.144.3.73
Bloom BA, Valentine BA, Gleed RD, Cable CS.No abstract available
Diversity of isolates of Rhodococcus equi from Australian thoroughbred horse farms.
Antonie van Leeuwenhoek    March 9, 1999   Volume 74, Issue 1-3 21-25 doi: 10.1023/a:1001791509073
Morton AC, Baseggio N, Peters MA, Browning GF.Pulsed field gel electrophoresis of restriction endonuclease digested genomic DNA from a collection of clinical isolates of Rhodococcus equi was used to compare strain diversity on different Thoroughbred horse farms over time. Restricted diversity was found among the isolates tested, as the same strains were detected on multiple farms and in multiple years. Marked variation occurred in strain prevalence with some strains being represented by single isolates, and the most prevalent by 26 isolates. There were dominant strains on some farms and the prevalence of some strains differed between farm...
International Congress, anniversary meeting. 20 years Swiss Equine Veterinary Association. Luzern, 11-13 December 1998. Abstracts.
Schweizer Archiv fur Tierheilkunde    March 5, 1999   Volume 140, Issue 11 445-480 
No abstract available
Urethrorectal fistula in a horse.
The Canadian veterinary journal = La revue veterinaire canadienne    March 5, 1999   Volume 40, Issue 2 122-124 
Cruz AM, Barber SM, Kaestner SB, Townsend HG.Anomalies of the urethra are uncommon. Urethrorectal fistula in horses has only been reported in foals and only in conjunction with other congenital anomalies. This report describes the diagnosis, surgical management, and possible etiologies of a unique case of urethrorectal fistula in a mature gelding.
Genetic polymorphisms of equine microsatellite loci: TKY16, TKY19 and TKY21.
Animal genetics    March 2, 1999   Volume 30, Issue 1 68-69 doi: 10.1046/j.1365-2052.1999.00323-4.x
Kakoi H, Tozaki T, Hirota K, Mashima S.No abstract available
Close association between sequence polymorphism in the KIT gene and the roan coat color in horses.
Mammalian genome : official journal of the International Mammalian Genome Society    March 2, 1999   Volume 10, Issue 3 283-288 doi: 10.1007/s003359900987
Marklund S, Moller M, Sandberg K, Andersson L.The roan coat color in horses is controlled by a dominant allele that is lethal in the homozygous condition. Phenotypic similarities to some pigmentation disorders in human and mouse, combined with comparative mapping data, identified KIT, encoding the mast cell growth factor receptor, as a major candidate gene for the roan locus (Rn). Rn has previously been mapped to equine linkage group (LG) II. In this study, LGII was expanded with KIT and PDGFRA (platelet-derived growth factor receptor alpha) by use of RFLP and linkage analysis. Moreover, highly significant linkage disequilibrium between R...
A synteny map of the horse genome comprised of 240 microsatellite and RAPD markers.
Animal genetics    March 2, 1999   Volume 30, Issue 1 1-9 doi: 10.1046/j.1365-2052.1999.00377.x
Shiue YL, Bickel LA, Caetano AR, Millon LV, Clark RS, Eggleston ML, Michelmore R, Bailey E, Guérin G, Godard S, Mickelson JR, Valberg SJ, Murray JD....To generate a domestic horse genome map we integrated synteny information for markers screened on a somatic cell hybrid (SCH) panel with published information for markers physically assigned to chromosomes. The mouse-horse SCH panel was established by fusing pSV2neo transformed primary horse fibroblasts to either RAG or LMTk mouse cells, followed by G418 antibiotic selection. For each of the 108 cell lines of the panel, we defined the presence or absence of 240 genetic markers by PCR, including 58 random amplified polymorphic DNA (RAPD) markers and 182 microsatellites. Thirty-three syntenic gr...
Five equine dinucleotide microsatellite loci HTG17, HTG20, HTG21, HTG28 and HTG31.
Animal genetics    March 2, 1999   Volume 30, Issue 1 70-71 doi: 10.1046/j.1365-2052.1999.00323-6.x
Lindgren G, Persson H, Ellegren H.No abstract available
Twelve equine dinucleotide repeats at microsatellite loci UCDEQ304, UCDEQ380, UCDEQ387, UCDEQ411, UCDEQ439, UCDEQ440, UCDEQ455, UCDEQ457, UCDEQ464, UCDEQ465, UCDEQ482 and UCDEQ497.
Animal genetics    March 2, 1999   Volume 30, Issue 1 69-70 doi: 10.1046/j.1365-2052.1999.00323-5.x
Eggleston-Stott ML, DelValle A, Bautista M, Dileanis S, Wictum E.No abstract available
Comparative mapping of 18 equine type I genes assigned by somatic cell hybrid analysis.
Mammalian genome : official journal of the International Mammalian Genome Society    March 2, 1999   Volume 10, Issue 3 271-276 doi: 10.1007/s003359900985
Caetano AR, Pomp D, Murray JD, Bowling AT.Polymerase chain reaction primers designed from horse cDNA sequences and from consensus sequences highly conserved in mammalian species were used to amplify markers for synteny mapping 18 equine type I genes. These markers were used to screen a horse-mouse somatic cell hybrid panel (UCDavis SCH). Fourteen primer sets amplified horse-specific fragments, while restriction enzyme digests of PCR products were used to distinguish the fragments amplified from horse and mouse with four primer sets. Synteny assignments were made based on correlation values between each marker tested and other markers ...
Purification and biochemical characterization of pulmonary surfactant protein A of horses.
American journal of veterinary research    February 27, 1999   Volume 60, Issue 2 169-173 
Hobo S, Ogasawara Y, Kuroki Y, Akino T, Yoshihara T.To characterize surfactant protein isolated from bronchoalveolar lavage fluids of healthy horses. Methods: 10 Thoroughbreds (5 males, 5 females; 26 to 40 months old) that did not have a history or clinical signs of respiratory tract disease. Methods: Bronchoalveolar lavage fluid (BALF) was obtained and centrifuged at 33,000 X g. Lipid was removed from precipitated fractions by means of extraction with 1-butanol, and organic solvent-insoluble protein precipitates were dialyzed against Tris buffer. The suspension was centrifuged, and supernatant was placed in a mannose-Sepharose affinity column,...
In vitro response of large colon arterial and venous rings to vasodilating drugs in horses.
American journal of veterinary research    February 27, 1999   Volume 60, Issue 2 204-210 
Sedrish SA, Venugopalan CS, Holmes EP, Koch CE, Moore RM.To determine in vitro vasomotor response of equine large colon arterial and venous rings with and without endothelium to vasodilator drugs, including dopamine (DOP), dopexamine (DPX), acepromazine (ACE), isoxsuprine (ISX), and nifedipine (NFP). Methods: 7 adult horses. Methods: Relaxation of large colon arteries and veins in response to vasodilating drugs was determined by measuring the change in tension of vessel rings when exposed to a cumulative concentration range (10(-8) to 10(-4)M) of each drug. Vessel rings, with and without endothelium, were mounted in organ baths, attached to a transd...
Heritability of recurrent exertional rhabdomyolysis in Thoroughbred racehorses.
American journal of veterinary research    February 27, 1999   Volume 60, Issue 2 250-256 
MacLeay JM, Valberg SJ, Sorum SA, Sorum MD, Kassube T, Santschi EM, Mickelson JR, Geyer CJ.To determine the likely mode of inheritance and identify probable foundation horses for recurrent exertional rhabdomyolysis (RER) in Thoroughbred (TB) racehorses. Methods: 4 families of TB racehorses with a high prevalence of RER, consisting of 3 to 53 horses/family, were used to determine mode of inheritance. Sixty-two TB horses with RER and 34 control TB racehorses without RER were used to identify probable foundation horses for the RER trait. Methods: RER was diagnosed by a veterinarian and verified by detecting high serum creatine kinase activity. Pedigrees dating from 1930 for all horses ...
Methods, applications and limitations of gait analysis in horses.
Veterinary journal (London, England : 1997)    February 25, 1999   Volume 157, Issue 1 7-22 doi: 10.1053/tvjl.1998.0297
Barrey E.Over the last 30 years, the increase in interest in horses for racing and riding activities has stimulated scientific research in equine locomotion. This paper presents a review of the measurement methods and their applications used to assess equine locomotion. After describing gaits and velocity-related changes in stride variables, the current applications of gait analysis are presented. The economic consequences of lameness justifies the great effort now being put into lameness quantification and prevention. To improve breeding and reduce the costs of training, early performance evaluation t...
Histopathological findings in the medial palmar and dorsomedial intercarpal ligaments of the equine midcarpal joint.
Veterinary journal (London, England : 1997)    February 25, 1999   Volume 157, Issue 1 23-29 doi: 10.1053/tvjl.1998.0261
Whitton RC, Rose RJ.Medial palmar intercarpal ligaments (MPICL) and dorsomedial intercarpal ligaments (DMICL) from the midcarpal joints of 11 adult horses in training were examined histopathologically. These were compared with ligaments from seven horses less than 12 months of age, and 10 grossly enlarged DMICLs of adult horses. Tearing of the MPICL was observed in 15 of 22 joints from adult horses. Collagen fibre bundles of the MPICLs generally were disorganized and poorly aligned, and there were large areas of loose connective tissue. In young horses there was more parallel alignment of collagen bundles and les...
[Detection of equine arteritis virus (EAV) in stallions–a contribution to the improvement of EAV diagnosis].
Berliner und Munchener tierarztliche Wochenschrift    February 24, 1999   Volume 112, Issue 1 10-13 
Starick E.Serum samples from 72 stallions were examined for the occurrence of antibodies against equine arteritis virus, of which 41 animals (57%) were found to be positive. 32 of the seropositive stallions were then screened for persistent EAV infection, before and after the breeding season. Semen samples were investigated by RT-PCR followed by dot blot hybridization and nested PCR, and by virus isolation on cell cultures as well. The carrier state was virologically confirmed in 11 of 32 stallions (34%) during the first and in 9 of 20 (45%) during the second investigation. RT-PCR followed by confirmato...
Morphometric study of the equine navicular bone: variations with breeds and types of horse and influence of exercise.
Journal of anatomy    February 24, 1999   Volume 193 ( Pt 4), Issue Pt 4 535-549 doi: 10.1046/j.1469-7580.1998.19340535.x
Gabriel A, Jolly S, Detilleux J, Dessy-Doize C, Collin B, Reginster JY.Navicular bones from the 4 limbs of 95 horses, classified in 9 categories, were studied. The anatomical bases were established for the morphometry of the navicular bone and its variations according to the category of horse, after corrections were made for front or rear limb, sex, weight, size and age. In ponies, navicular bone measurements were smallest for light ponies and regularly increased with body size, but in horses, navicular bone dimensions were smallest for the athletic halfbred, intermediate for draft horse, thoroughbreds and sedentary halfbreds and largest for heavy halfbreds. The ...
Accuracy and precision of the portable StatPal II and the laboratory-based NOVA stat profile 1 for measurement of pH, P(CO2), and P(O2) in equine blood.
Veterinary surgery : VS    February 20, 1999   Volume 28, Issue 1 67-76 doi: 10.1053/jvet.1999.0067
Klein LV, Soma LR, Nann LE.To investigate the accuracy and precision of the portable, battery-powered StatPal II and the laboratory-based NOVA StatProfile 1 blood gas and pH analyzers for use in analysis of equine blood. Methods: Patient sample comparison and whole blood tonometry. Methods: Patient sample comparison: 125 arterial or venous blood samples from 49 healthy, awake, or anesthetized horses or ponies. Tonometry: venous blood samples from 11 healthy Thoroughbred horses. Methods: Arterial and venous blood taken from awake and anesthetized equine patients was placed in an ice-water bath, then analyzed within 30 mi...
Unique localization of protein gene product 9.5 in type B synoviocytes in the joints of the horse.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society    February 20, 1999   Volume 47, Issue 3 343-352 doi: 10.1177/002215549904700308
Kitamura HP, Yanase H, Kitamura H, Iwanaga T.Fibroblast-like (Type B) synoviocytes are cells in the synovial membrane that are responsible for production of both synovial fluid and the extracellular matrix in the synovial intima. Immunostaining of the horse synovial membrane for protein gene product (PGP) 9.5, which is a neuron-specific ubiquitin C-terminal hydrolase, demonstrated selective localization of the immunoreactivity in a synoviocyte population different from acid phosphatase-positive Type A synoviocytes. The immunoreactive cells were lined up in the synovial intima and extended dendritic processes towards the joint cavity to f...
Scrotal heat stress induces altered sperm chromatin structure associated with a decrease in protamine disulfide bonding in the stallion.
Biology of reproduction    February 20, 1999   Volume 60, Issue 3 615-620 doi: 10.1095/biolreprod60.3.615
Love CC, Kenney RM.A variety of testicular insults can induce changes in the structure of spermatozoal chromatin, resulting in spermatozoal DNA that is more susceptible to acid-induced denaturation. The degree of change in the DNA can be measured using the sperm chromatin structure assay (SCSA). The SCSA measures the relative amounts of single- and double-stranded DNA after staining with the metachromatic dye, acridine orange. Here we used a stallion model (n = 4) to study the effects of scrotal heat stress on spermatozoal DNA. This model was created by insulating stallion testes for 48 h and collecting sperm da...
Ovarian disorders causing colic in neonatal foals.
Journal of the American Veterinary Medical Association    February 19, 1999   Volume 214, Issue 3 329-330 
Fischer AT.No abstract available