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American journal of veterinary research2026; 87(6); ajvr.25.12.0441; doi: 10.2460/ajvr.25.12.0441

A pilot study to assess feasibility of a computer-assisted surgery system for navigation in the equine cervical spine.

Abstract: To validate the accuracy of the Synaptive Medical computer-assisted surgery (CAS) system for navigation in the equine cervical spine, focusing on anatomical targets that require precise localization. Unassigned: 3 equine cervical spine cadavers were used (C1-T1) for an experimental study design. A custom fiducial array was mounted into the dorsal spinous process of C2, with additional fiducial markers distributed for landmark registration. Four participants with varying surgical expertise used the Synaptive Medical CAS system to navigate 9 radiodense pins into 3 anatomical targets, including the intervertebral foramen, articular process joint, and intervertebral disc. Pre- and postprocedural CT scans were used to evaluate pin placement accuracy, defined as the Euclidean distance between planned and achieved points. The procedure duration was also recorded. Unassigned: The mean navigation error between the planned and reached target points was 11.33 ± 11.02 mm. Surgical experience influenced procedure duration; however, it did not significantly affect accuracy. Additionally, our results suggested that placement of a fiducial array into the dorsal spinous process of C2 allowed for successful registration. Unassigned: Use of the Synaptive Medical CAS system for navigation-assisted procedures in the equine cervical spine is feasible and may enhance surgical precision in veterinary applications. Unassigned: This study provides insight into the potential integration of CAS into the clinical application of equine cervical spine procedures. This validation supports that CAS can be an option for minimally invasive approaches aimed at reducing clinical complications when accessing the equine cervical spine.
Publication Date: 2026-02-18 PubMed ID: 41707326DOI: 10.2460/ajvr.25.12.0441Google Scholar: Lookup
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  • Journal Article

Summary

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Research Overview

  • This study evaluated the feasibility and accuracy of the Synaptive Medical computer-assisted surgery (CAS) system for guiding surgical navigation in the equine cervical spine using cadaver models.
  • The aim was to determine whether the system could accurately assist with targeting specific anatomical structures critical in spine surgery.

Introduction and Purpose

  • The cervical spine in horses is a complex area where precise surgical navigation is essential to avoid complications.
  • Computer-assisted surgery (CAS) systems are emerging technologies designed to improve surgical precision by providing real-time navigational guidance.
  • The Synaptive Medical CAS system was selected for evaluation to see if it could be effectively used for equine cervical spine surgery.
  • The primary goals were to test the accuracy of the system and assess whether surgical experience affected outcomes.

Materials and Methods

  • Three equine cervical spine cadavers (from vertebrae C1 to T1) were prepared for an experimental pilot study.
  • A custom fiducial array (a marker system used for tracking and registration) was mounted on the dorsal spinous process of the second cervical vertebra (C2), serving as a fixed reference point for navigation.
  • Additional fiducial markers were distributed around the area to enhance landmark registration for the navigation system.
  • Four participants with different levels of surgical experience were recruited to perform navigation tasks using the CAS system.
  • Each participant guided radiodense pins into three distinct anatomical targets within the cervical spine:
    • Intervertebral foramen – the opening where nerves exit the spine
    • Articular process joint – a joint in the spine critical for motion and stability
    • Intervertebral disc – the cushioning structure between vertebrae
  • Pre- and post-procedural computed tomography (CT) scans were used to measure the positions of planned target points and actual pin placements.
  • Accuracy was quantified by calculating the Euclidean distance between the planned and achieved target points.
  • Procedure duration was also recorded to measure how surgical experience may influence time taken for navigation-assisted pin placement.

Results

  • The average navigation error across all placements was 11.33 mm, with a high variability indicated by a standard deviation of 11.02 mm.
  • This shows that while some placements were very accurate, others had larger deviations from the planned target.
  • Fiducial array placement on the dorsal spinous process of C2 proved effective for registration during the navigation procedure, meaning the system could reliably use these markers for spatial orientation.
  • Surgical experience impacted the duration of the procedure, with more experienced surgeons typically completing the task faster.
  • However, experience did not have a statistically significant effect on the accuracy of pin placement, suggesting that the CAS system may help to level the playing field regarding precision.

Conclusions and Implications

  • The Synaptive Medical CAS system is feasible for use in equine cervical spine navigation-assisted surgery, showing promise for improving surgical precision in veterinary procedures.
  • This pilot validation supports the integration of CAS technology into minimally invasive approaches that seek to reduce complications by enhancing accurate targeting of critical anatomical structures.
  • The findings suggest CAS could serve as a valuable tool in clinical veterinary practice, potentially improving outcomes in complicated equine spine surgeries.
  • Further studies with larger sample sizes and live animal models would be necessary to confirm system performance and clinical benefits.

Cite This Article

APA
Masca SA, Easley JT, Koch DW, Aragon JM, Winston SE, Bonilla AF. (2026). A pilot study to assess feasibility of a computer-assisted surgery system for navigation in the equine cervical spine. Am J Vet Res, 87(6), ajvr.25.12.0441. https://doi.org/10.2460/ajvr.25.12.0441

Publication

ISSN: 1943-5681
NlmUniqueID: 0375011
Country: United States
Language: English
Volume: 87
Issue: 6
PII: ajvr.25.12.0441

Researcher Affiliations

Masca, Samantha A
  • Preclinical Surgical Research Laboratory, Department of Clinical Sciences, Colorado State University, Fort Collins, CO.
Easley, Jeremiah T
  • Preclinical Surgical Research Laboratory, Department of Clinical Sciences, Colorado State University, Fort Collins, CO.
Koch, Drew W
  • Preclinical Surgical Research Laboratory, Department of Clinical Sciences, Colorado State University, Fort Collins, CO.
Aragon, Juan M
  • Preclinical Surgical Research Laboratory, Department of Clinical Sciences, Colorado State University, Fort Collins, CO.
Winston, Sam E
  • Orthopaedic Bioengineering Research Laboratory, Colorado State University, Fort Collins, CO.
Bonilla, Andres F
  • Preclinical Surgical Research Laboratory, Department of Clinical Sciences, Colorado State University, Fort Collins, CO.

MeSH Terms

  • Animals
  • Horses / surgery
  • Cervical Vertebrae / surgery
  • Surgery, Computer-Assisted / veterinary
  • Surgery, Computer-Assisted / methods
  • Surgery, Computer-Assisted / instrumentation
  • Pilot Projects
  • Cadaver
  • Feasibility Studies
  • Tomography, X-Ray Computed / veterinary

Citations

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