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The Veterinary clinics of North America. Equine practice2007; 23(2); 317-328; doi: 10.1016/j.cveq.2007.03.009

An evidence-based approach to clinical questions in the practice of equine neurology.

Abstract: The practice of equine neurology has special challenges posed by the size of the animal being examined. Many diagnostic procedures routinely used in small animal practice are unsafe when applied to the equine patient or unavailable to the equine practitioner. Therefore, astute observation is the mainstay of making a neuroanatomic diagnosis, and detailed evidence on the deficits present may be difficult to obtain. Because clinical observation can sometimes be ambiguous and somewhat subjective, it is even more important to approach equine neurology from an evidence-based point of view. Here, such an approach is outlined for the diagnosis of cervical vertebral compressive myelopathy (CVCM), one of the most common noninfectious causes of equine neurologic disease. This article is an attempt to summarize all aspects of making a diagnosis of CVCM on the basis of signalment, clinical examination, ancillary diagnostic tests, and pathologic examination. Each of these considerations has inherent limitations regarding diagnostic accuracy, which are discussed.
Publication Date: 2007-07-10 PubMed ID: 17616316DOI: 10.1016/j.cveq.2007.03.009Google Scholar: Lookup
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Summary

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This research article discusses the unique challenges in diagnosing neurological conditions in horses, emphasizing the necessity of evidence-based procedures. The study specifically outlines an evidence-based approach for diagnosing cervical vertebral compressive myelopathy (CVCM), a common non-infectious neurological disease in horses.

Context and Challenges in Equine Neurology

  • The article begins by highlighting unique challenges inherent to the field of equine neurology due mostly to the size of the animals involved. The discourse acknowledges the fact that many diagnostic procedures that are standard in small animal medical practice are not safe or practical to use on horses, which complicates the process of diagnosis.
  • Given these limitations, detailed observations of the animal in question become pivotal in diagnosing neurological conditions in horses.
  • Yet, due to the subjective and sometimes ambiguous nature of these observations, the article underlines the importance of applying an evidence-based approach to this field in an effort to standardize and increase the accuracy in diagnosis.

Evidence-based Approach for CVCM

  • The focus of this research is on introducing an evidence-based approach for diagnosing Cervical Vertebral Compressive Myelopathy (CVCM), which is one of the most common non-infectious neurological diseases in horses.
  • The comprehensive guide presents an evidence-based procedure to diagnose CVCM that involves evaluation of the horse’s signalment (age, breed, sex, etc.), a clinical examination, conducting ancillary diagnostic tests, and a detailed pathologic examination.
  • However, each step of this proposed process has inherent limitations with respect to diagnostic accuracy, which the author discusses throughout the paper.

Relevance and Conclusion

  • The study underscores the necessity of evidence-based methods in equine neurology to circumvent the challenges associated with the size of the animals and the limitations of diagnostic methods that are applicable.
  • Introducing standardized evidence-based procedures can improve diagnostic accuracy, and ultimately, the quality of veterinary care provided to horses.

Cite This Article

APA
Van Biervliet J. (2007). An evidence-based approach to clinical questions in the practice of equine neurology. Vet Clin North Am Equine Pract, 23(2), 317-328. https://doi.org/10.1016/j.cveq.2007.03.009

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 23
Issue: 2
Pages: 317-328

Researcher Affiliations

Van Biervliet, Jérôme
  • Neuronal Cell Biology and Gene Transfer Laboratory, Department for Molecular and Developmental Genetics, VIB, Leuven, Belgium. jerome.vanbiervliet@med.kuleuven.be

MeSH Terms

  • Animals
  • Diagnosis, Differential
  • Evidence-Based Medicine
  • Horse Diseases / diagnosis
  • Horses
  • Neurologic Examination / veterinary
  • Neurology / methods
  • Spinal Cord Compression / diagnosis
  • Spinal Cord Compression / veterinary
  • Veterinary Medicine / methods
  • Veterinary Medicine / standards

Citations

This article has been cited 7 times.
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    doi: 10.1093/af/vfac036pubmed: 35711509google scholar: lookup
  2. Bergmann W, de Mik-van Mourik M, Veraa S, van den Broek J, Wijnberg ID, Back W, Gröne A. Cervical articular process joint osteochondrosis in Warmblood foals. Equine Vet J 2020 Sep;52(5):664-669.
    doi: 10.1111/evj.13245pubmed: 32009243google scholar: lookup
  3. Rijckaert J, Pardon B, Saey V, Raes E, Van Ham L, Ducatelle R, van Loon G, Deprez P. Determination of magnetic motor evoked potential latency time cutoff values for detection of spinal cord dysfunction in horses. J Vet Intern Med 2019 Sep;33(5):2312-2318.
    doi: 10.1111/jvim.15576pubmed: 31490026google scholar: lookup
  4. Aleman M, Dimock AN, Wisner ER, Prutton JW, Madigan JE. Atlanto-axial approach for cervical myelography in a Thoroughbred horse with complete fusion of the atlanto-occipital bones. Can Vet J 2014 Nov;55(11):1069-73.
    pubmed: 25392550
  5. Martin-Vaquero P, da Costa RC. Evaluation of traditional and novel radiographic vertebral ratios in Great Danes with versus without cervical spondylomyelopathy. Vet Radiol Ultrasound 2014 Sep-Oct;55(5):488-95.
    doi: 10.1111/vru.12159pubmed: 24698393google scholar: lookup
  6. Hellige M, Schröder C, Seehusen F, Cavalleri JM, Rohn K, Stadler P, Geburek F. Computed tomographic myelography of the cranial cervical spine in Warmblood horses with no spinal pathology-Inter- and intravertebral ratios and distribution of contrast columns in neutral and flexed cervical spine. Equine Vet J 2025 Sep;57(5):1375-1386.
    doi: 10.1111/evj.14552pubmed: 40551666google scholar: lookup
  7. Journée SL, Journée HL, Bergmann W, Chantziaras I, Vanderperren K, Raes E, Reed SM, de Bruijn CM, Berends HI, Delesalle CJG. Evaluation of the diagnostic value of transcranial electrical stimulation (TES) to assess neuronal functional integrity in horses. Front Neurosci 2024;18:1342803.
    doi: 10.3389/fnins.2024.1342803pubmed: 38665290google scholar: lookup