Antifungal Therapy in Equine Ocular Mycotic Infections.
Abstract: Fungi are clinically important causes of ocular infections in the horse. Keratomycosis is the most common; however, a diverse range of mycotic infections, affecting numerous ocular tissues, may be encountered. Many equine mycoses are diagnostic and therapeutic challenges. Prompt and appropriate treatment is essential to minimize morbidity and reduce the likelihood of vision loss. Knowledge of the characteristics and properties of equine ophthalmology antifungal medications is essential to selecting an optimal treatment strategy, including selection of appropriate medication and effective administration route. Newer delivery methods and devices are available and can contribute to an improved outcome in select situations.
Copyright © 2017 Elsevier Inc. All rights reserved.
Publication Date: 2017-09-27 PubMed ID: 28958862DOI: 10.1016/j.cveq.2017.08.001Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Review
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This research article discusses the treatment of fungal infections in the eyes of horses, with an emphasis on diagnosing different types of mycotic infections and selecting appropriate treatments to prevent vision loss and other complications.
Overview of Equine Ocular Mycotic Infections
- The study discusses several types of ocular mycoses (fungal infections) that infect equine (horse) species, with the most common being keratomycosis. These infections can affect various ocular tissues, resulting in different diagnostic and therapeutic challenges.
Importance of Immediate and Appropriate Treatment
- According to the research, prompt and efficient treatment is crucial to limit the morbidity rate and minimize the chances of vision loss in infected horses. Addressing ocular mycoses early contributes to better health and productivity of the horses.
Understanding Antifungal Medications Specific to Equine Ophthalmology
- This paper emphasizes the importance of understanding the properties and characteristics of antifungal medications used in equine ophthalmology, the study of horse’s eyes and their diseases. This understanding is key to selecting the best treatment strategy, which includes choosing the right drug and its effective administration route.
Innovation in Delivery Methods
- The authors also discuss newer methods of delivering medications and medical devices that can improve the outcomes of equine ocular mycosis treatments. Better delivery methods ensure that medication reaches the affected ocular tissue more effectively and efficiently, leading to improved treatments and faster recovery.
Cite This Article
APA
Ledbetter EC.
(2017).
Antifungal Therapy in Equine Ocular Mycotic Infections.
Vet Clin North Am Equine Pract, 33(3), 583-605.
https://doi.org/10.1016/j.cveq.2017.08.001 Publication
Researcher Affiliations
- Department of Clinical Sciences, Cornell University College of Veterinary Medicine, Cornell University Hospital for Animals, CVM Box 34, Ithaca, NY 14853, USA. Electronic address: ecl32@cornell.edu.
MeSH Terms
- Animals
- Antifungal Agents / therapeutic use
- Eye Infections, Fungal / drug therapy
- Eye Infections, Fungal / veterinary
- Horse Diseases / drug therapy
- Horses
Citations
This article has been cited 5 times.- Mora-Pereira M, Abarca EM, Duran S, Ravis W, McMullen RJ Jr, Fischer BM, Lee YP, Wooldridge AA. Sustained-release voriconazole-thermogel for subconjunctival injection in horses: ocular toxicity and in-vivo studies. BMC Vet Res 2020 Apr 16;16(1):115.
- Mustikka MP, Grönthal TSC, Pietilä EM. Equine infectious keratitis in Finland: Associated microbial isolates and susceptibility profiles. Vet Ophthalmol 2020 Jan;23(1):148-159.
- Cullen M, Jacob ME, Cornish V, VanderSchel IQ, Cotter HVT, Cubeta MA, Carbone I, Gilger BC. Multi-locus DNA sequence analysis, antifungal agent susceptibility, and fungal keratitis outcome in horses from Southeastern United States. PLoS One 2019;14(3):e0214214.
- Elad D. Therapy of Non-Dermatophytic Mycoses in Animals. J Fungi (Basel) 2018 Oct 30;4(4).
- Roberts D, Salmon J, Cubeta MA, Gilger BC. Phase-Dependent Differential In Vitro and Ex Vivo Susceptibility of Aspergillus flavus and Fusarium keratoplasticum to Azole Antifungals. J Fungi (Basel) 2023 Sep 26;9(10).
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists