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Home / Equine Research Bank / Animals (Basel) / Assessment of Age Effects on Ovarian Hemodynamics Using Dopp...
Animals : an open access journal from MDPI2021; 11(8); 2339; doi: 10.3390/ani11082339

Assessment of Age Effects on Ovarian Hemodynamics Using Doppler Ultrasound and Progesterone Concentrations in Cycling Spanish Purebred Mares.

Abstract: In equine reproduction, accurate and timely detection of the moment of ovulation is of great importance. Power Doppler ultrasound technology is a non-invasive method that enables to assess the morpho-echogenic features and blood flow changes during the estral cycle in mares. The objective of the present study was to evaluate the influence of age on ultrasonographic parameters (follicular diameter, follicular blood flow-FBF, corpus luteum (CL) area and corpus luteum blood flow-CLBF) and blood plasma progesterone concentrations in cycling Spanish Purebred mares (15 less than 8 years old and 15 equal o higher than 8 years old). The ultrasound images obtained were analyzed with the Image Colour Summarizer software, which allows the quantification of the pixels of each image. Young mares had significantly higher FBF, CLBF and plasma progesterone levels. Moreover, linear regression analysis showed that blood progesterone levels could be predicted in both groups from CLBF with moderate precision and accuracy. In conclusion, Power Doppler was useful to assess ovarian hemodynamics. Our results support that age is a factor that significantly influences FBF and CLBF as well as blood progesterone concentration in mares. More studies would be needed to develop high precision and accuracy predictive models of blood progesterone concentration from CLBF measured by Power Doppler.
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Publication Date: 2021-08-08 PubMed ID: 34438797PubMed Central: PMC8388672DOI: 10.3390/ani11082339Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research investigates the effect of age on ovarian blood flow and progesterone concentrations in Spanish Purebred mares using power Doppler ultrasound technology, indicating age significantly influences these parameters, and forecasting progesterone levels based on blood flow measurements is moderately accurate.

Objective and Methodology

  • The research aimed to analyze the impact of age on various ultrasonic parameters (like follicular diameter, corpus luteum area), ovarian blood flow, and blood progesterone concentrations in Spanish Purebred mares. It assessed two different age groups: mares younger than 8 years old and those that were equal to or older than 8.
  • Doppler ultrasound technology was employed for the study. This non-invasive technique is highly effective in determining alterations in blood flow and morpho-echogenic features during the estral (reproductive) cycle in mares.
  • The ultrasound images acquired were scrutinized with Image Colour Summarizer software. This analysis tool enables the quantification of the pixels of each image, providing detailed information about the observed parameters.

Findings

  • Young mares (less than 8 years old) exhibited higher follicular blood flow (FBF), corpus luteum blood flow (CLBF), and plasma progesterone levels when compared with their older counterparts.
  • Using linear regression analysis, the researchers inferred that blood progesterone levels could be forecasted from CLBF with a moderate degree of precision and accuracy in both age groups.

Conclusion

  • The study successfully established the efficiency of Power Doppler ultrasound in evaluating ovarian hemodynamics. It further established that age significantly impacts FBF, CLBF, and blood progesterone concentration in mares.
  • The researchers concluded that more studies are needed to develop predictive models with high accuracy and precision for determining blood progesterone concentrations from CLBF measurements made by Power Doppler ultrasound.

Cite This Article

APA
Requena F, Campos MJAPM, Martínez Marín AL, Camacho R, Giráldez-Pérez RM, Agüera EI. (2021). Assessment of Age Effects on Ovarian Hemodynamics Using Doppler Ultrasound and Progesterone Concentrations in Cycling Spanish Purebred Mares. Animals (Basel), 11(8), 2339. https://doi.org/10.3390/ani11082339

Publication

Animals : an open access journal from MDPI
ISSN: 2076-2615
NlmUniqueID: 101635614
Country: Switzerland
Language: English
Volume: 11
Issue: 8
PII: 2339

Researcher Affiliations

Requena, Francisco
  • Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Ctra. Madrid-Cádiz km 396, 14071 Córdoba, Spain.
Campos, María Joana A P M
  • Departamento de Producción Animal, Universidad de Córdoba, Ctra. Madrid-Cádiz km 396, 14071 Córdoba, Spain.
Martínez Marín, Andrés Luis
  • Departamento de Producción Animal, Universidad de Córdoba, Ctra. Madrid-Cádiz km 396, 14071 Córdoba, Spain.
Camacho, Rocío
  • Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Ctra. Madrid-Cádiz km 396, 14071 Córdoba, Spain.
Giráldez-Pérez, Rosa M
  • Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Ctra. Madrid-Cádiz km 396, 14071 Córdoba, Spain.
Agüera, Estrella I
  • Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Ctra. Madrid-Cádiz km 396, 14071 Córdoba, Spain.

Conflict of Interest Statement

The authors declare no conflict of interest.

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Citations

This article has been cited 1 times.
  1. Perea J, Arias R. Competitiveness of Spanish Local Breeds. Animals (Basel) 2022 Aug 12;12(16).
    doi: 10.3390/ani12162060pubmed: 36009650google scholar: lookup
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