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The Veterinary clinics of North America. Equine practice2002; 17(3); 579-588; doi: 10.1016/s0749-0739(17)30053-6

Botulism in the horse.

Abstract: Botulism should be considered in cases where weakness, paralysis, or intolerance to exercise might be seen in the horse. Dysphagia may also be present, although it is not a consistent finding. Potential sources include carrion in hay, moldy or otherwise rotted vegetation or forage, birds carrying material from animal burial or other similar sites, and contaminated carcasses on-site. Horses, especially foals, may also suffer from toxicoinfectious botulism, a condition where the C. botulinum might colonize and produce toxin within the gastrointestinal tract. Wounds also may harbor the organism and otherwise promote botulism. Diagnosis of botulism is often a clinical diagnosis backed up by elimination of other possible infectious, injurious, or toxic causes of weakness of the horse. Definitive diagnosis and type identification in the laboratory are difficult and usually require a suitable sample of the source material. Treatment often is unrewarding unless a case is identified early and the proper antitoxin is readily available. Prevention involves common sense approaches to feeding and care of the horse and, where possible, judicious use of vaccination in endemic areas.
Publication Date: 2002-01-10 PubMed ID: 11780288DOI: 10.1016/s0749-0739(17)30053-6Google Scholar: Lookup
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Summary

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The abstract discusses an investigation into botulism in horses, its potential sources, symptoms, diagnosis, treatment, and prevention methods.

Botulism in Horses

The paper explores botulism in horses, a potentially fatal disease that can cause weakness, paralysis, and exercise intolerance in afflicted animals. Indications might also include swallowing difficulties, although this isn’t always present.

  • The potential sources of the disease are identified as carrion (decaying animal remains) in hay, moldy or rotted vegetation, birds carrying potentially contaminated material from animal burial sites or similar areas, and contaminated carcasses on-site.

Causes and Diagnosis

The research further investigates the circumstances under which botulism might occur.

  • Particularly in foals, a condition called toxicoinfectious botulism, which is when the bacterium Clostridium botulinum colonizes and produces toxins within the GI tract, might occur.
  • Another way horses get infected is through their wounds, which might serve as a harbor for the causative organism.
  • Diagnosing botulism is often done clinically, primarily by ruling out other infectious, injurious, or toxic causes that could lead to a horse’s weakness.
  • Still, a definitive diagnosis and identification of the botulism type in a laboratory setting are challenging. It usually requires a suitable sample of the source material responsible for the disease.

Treatment and Prevention

The paper also discusses the complexity of treating botulism and suggests various prevention measures.

  • Treatment is often difficult unless the case is identified early and the correct antitoxin is readily accessible.
  • Prevention involves practical approaches to equine care and feeding, including, where possible, using vaccination judiciously in areas where botulism is prevalent.

Cite This Article

APA
Galey FD. (2002). Botulism in the horse. Vet Clin North Am Equine Pract, 17(3), 579-588. https://doi.org/10.1016/s0749-0739(17)30053-6

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 17
Issue: 3
Pages: 579-588

Researcher Affiliations

Galey, F D
  • Department of Veterinary Sciences and Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, Wyoming, USA. fgaley@uwyo.edu

MeSH Terms

  • Animals
  • Botulism / diagnosis
  • Botulism / physiopathology
  • Botulism / prevention & control
  • Botulism / veterinary
  • Clostridium botulinum / immunology
  • Horse Diseases / diagnosis
  • Horse Diseases / microbiology
  • Horse Diseases / physiopathology
  • Horse Diseases / prevention & control
  • Horses
  • Vaccination / veterinary

References

This article includes 33 references

Citations

This article has been cited 6 times.
  1. Souza LL, Lima AS, Martins AS, Silva TA, Borsanelli AC, Dutra IS, Pupin RC, Gomes DC, Lemos RA. Outbreak of equine botulism type C associated with consumption of baleage in Brazil. J Vet Diagn Invest 2026 Mar;38(2):302-304.
    doi: 10.1177/10406387251399152pubmed: 41504204google scholar: lookup
  2. Slavik K, Whitlock R, Johnson A. Equine botulism. Equine Vet J 2026 Mar;58(2):333-347.
    doi: 10.1111/evj.14542pubmed: 40518698google scholar: lookup
  3. Kabir A, Lamichhane B, Habib T, Adams A, El-Sheikh Ali H, Slovis NM, Troedsson MHT, Helmy YA. Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond-A Comprehensive Review. Antibiotics (Basel) 2024 Jul 29;13(8).
    doi: 10.3390/antibiotics13080713pubmed: 39200013google scholar: lookup
  4. Le Bouquin S, Lucas C, Souillard R, Le Maréchal C, Petit K, Kooh P, Jourdan-Da Silva N, Meurens F, Guillier L, Mazuet C. Human and animal botulism surveillance in France from 2008 to 2019. Front Public Health 2022;10:1003917.
    doi: 10.3389/fpubh.2022.1003917pubmed: 36504929google scholar: lookup
  5. Uzal FA, Navarro MA, Asin J, Henderson EE. Clostridial Diseases of Horses: A Review. Vaccines (Basel) 2022 Feb 17;10(2).
    doi: 10.3390/vaccines10020318pubmed: 35214776google scholar: lookup
  6. Pellett S, Yaksh TL, Ramachandran R. Current status and future directions of botulinum neurotoxins for targeting pain processing. Toxins (Basel) 2015 Nov 4;7(11):4519-63.
    doi: 10.3390/toxins7114519pubmed: 26556371google scholar: lookup