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Home / Equine Research Bank / Equine Vet J / Ceftiofur use and antimicrobial stewardship in the horse.
Equine veterinary journal2023; 55(6); 944-961; doi: 10.1111/evj.13930

Ceftiofur use and antimicrobial stewardship in the horse.

Abstract: Equine practitioners require recommendations that support antimicrobial stewardship and avoid generating resistance to medically important antibiotics. This review examines current inadequacies in antimicrobial stewardship standards within the veterinary community, related to antimicrobial categorisation and prescribing practices. Resistance to cephalosporin antibiotics in horses is also described. Properties of cephalosporin antibiotics are outlined and equine-specific studies of ceftiofur, a third-generation cephalosporin antibiotic with medical importance, are detailed. Readers are provided with recommendations that encourage appropriate use of ceftiofur, citing the evidence available in horses.
© 2023 The Authors. Equine Veterinary Journal published by John Wiley & Sons Ltd on behalf of EVJ Ltd.
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Publication Date: 2023-02-16 PubMed ID: 36733237DOI: 10.1111/evj.13930Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article discusses the need for better antimicrobial stewardship in equine healthcare, focusing on the use of Ceftiofur, a third-generation cephalosporin. It assesses current antimicrobial categorisation, prescribing practices, and resistance, providing guidelines for the appropriate application of Ceftiofur in horses.

Antimicrobial Stewardship in Equines

  • The paper first establishes the need for improved antimicrobial stewardship in equine practitioners. They need guidelines that help prevent antibiotic resistance, an important public health concern. An ineffective antimicrobial stewardship can lead to increased antimicrobial resistance, where bacteria evolve to resist the effects of antibiotics.
  • The existing antimicrobial stewardship standards in the veterinary community show certain shortcomings, especially regarding the categorisation and prescribing of antimicrobials. The study indicates a need for better understanding and practices in this area.

Resistance to Cephalosporin

  • The article delves into the occurrence of resistance to cephalosporin antibiotics in horses. Cephalosporin is a class of antibiotics widely used in human and veterinary medicine, so resistance to these antibiotics can have major implications for health treatment.

Ceftiofur Properties and Effects in Horses

  • Properties of cephalosporin antibiotics, especially Ceftiofur, a third-generation cephalosporin, are described in detail. Ceftiofur has significant medical importance as it is often used to treat respiratory diseases in horses.
  • The research article then turns its focus on equine-specific studies of Ceftiofur. By examining these studies, the article provides an in-depth understanding of how this particular antibiotic affects horses and how resistance to it may build up.

Recommendations for Ceftiofur Use

  • The findings serve as a basis for making recommendations about the appropriate use of Ceftiofur in horses. The guidelines aim to preserve the effectiveness of this essential antibiotic by preventing unnecessary overuse and managing resistance.

Cite This Article

APA
Ryan CA, McNeal CD, Credille BC. (2023). Ceftiofur use and antimicrobial stewardship in the horse. Equine Vet J, 55(6), 944-961. https://doi.org/10.1111/evj.13930

Publication

Equine veterinary journal
ISSN: 2042-3306
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 55
Issue: 6
Pages: 944-961

Researcher Affiliations

Ryan, Clare A
  • Department of Large Animal Medicine, University of Georgia, Athens, Georgia, USA.
McNeal, Christina D
  • Department of Large Animal Medicine, University of Georgia, Athens, Georgia, USA.
Credille, Brenton C
  • Department of Population Health, University of Georgia, Athens, Georgia, USA.

MeSH Terms

  • Horses
  • Animals
  • Antimicrobial Stewardship
  • Cephalosporins / therapeutic use
  • Anti-Bacterial Agents / therapeutic use

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