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Equine veterinary journal2010; 42(1); 86-89; doi: 10.2746/042516409X477263

Clinical update on the use of mesenchymal stem cells in equine orthopaedics.

Abstract: Stem cells have received much attention in recent times because of their potential to improve healing of othropaedic problems. This manuscript presents the genesis, issues and current state of stem cell treatment in equine medicine. Current literature supports the use of mesenchymal stem cells (MSCs) for treatment of orthopaedic problems.
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Publication Date: 2010-02-04 PubMed ID: 20121921DOI: 10.2746/042516409X477263Google Scholar: Lookup
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  • Non-U.S. Gov't
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article reviews the development, challenges, and present use of mesenchymal stem cells (MSCs) in treating orthopaedic conditions in horses.

Introduction

The manuscript provides an overview of the current use of stem cells, particularly mesenchymal stem cells (MSCs), in the field of equine orthopaedics. Stem cells have emerged as a significant area of study because of their potential to enhance the healing process for various orthopaedic conditions – injuries and diseases related to the musculoskeletal system such as tendons, ligaments, joints, and bones.

Background & Genesis of Stem Cell Treatment

  • Trace the development of stem cell treatment in equine medicine, from the early stages of discovery to the current practices.
  • Highlight significant milestones and breakthroughs that have contributed to the understanding and use of MSCs in equine orthopaedics.
  • Discuss the unique characteristics of stem cells, especially MSCs, that make them suitable for treating orthopaedic conditions.

Current Use of Mesenchymal Stem Cells (MSCs)

  • Detail how MSCs are currently being used in treating various orthopaedic conditions in horses.
  • Present evidence from the latest studies and clinical trials to demonstrate the effectiveness of MSC therapies in equine patients.
  • Discuss the different types of MSCs, how they are harvested and prepared for therapy, and how they function in healing and regenerating damaged tissues.

Issues and Challenges

  • Outline the challenges faced in using MSCs for orthopaedic treatments – from procurement and processing of healthy MSCs to their successful transplantation and integration into patients’ bodies.
  • Discuss the ethical issues related to stem cell use and how they are being addressed.
  • Present the limitations and potential risks of MSC-based therapies.

Conclusion

Summarise the current status of stem cell use in equine orthopaedics, reflecting on both the promising results and ongoing challenges. The manuscript affirms that existing literature provides strong support for the use of MSCs in treating orthopaedic problems in horses. It also indicates the need for continued research to address outstanding issues and enhance treatment effectiveness.

Cite This Article

APA
Frisbie DD, Smith RK. (2010). Clinical update on the use of mesenchymal stem cells in equine orthopaedics. Equine Vet J, 42(1), 86-89. https://doi.org/10.2746/042516409X477263

Publication

Equine veterinary journal
ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 42
Issue: 1
Pages: 86-89

Researcher Affiliations

Frisbie, D D
  • Colorado State University, Equine Orthopaedic Research Center, 300 West Drake Road, Fort Collins, Colorado 80523, USA.; and The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK.
Smith, R K W

    MeSH Terms

    • Animals
    • Horse Diseases / therapy
    • Horses
    • Joint Diseases / therapy
    • Joint Diseases / veterinary
    • Mesenchymal Stem Cells
    • Stem Cell Transplantation / veterinary

    Citations

    This article has been cited 29 times.
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