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Home / Equine Research Bank / J Vet Emerg Crit Care (San Antonio) / Comparative evaluation of clinical findings and prognostic o...
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)2021; 31(5); 619-628; doi: 10.1111/vec.13093

Comparative evaluation of clinical findings and prognostic outcome parameters in hospitalized, critically ill neonatal foals and crias.

Abstract: Species-related differences in the prevalence, manifestation, and outcome of neonatal illness may impact management practices of neonatal intensive care. The study aimed to elucidate similarities between disease manifestations and mortality risks of critically ill (CI) neonatal crias and foals admitted to the same referral center. Methods: A comparative, retrospective cohort evaluation of two species (camelid and equine). Methods: The study was conducted in a University hospital. Methods: Two hundred and forty-six CI neonatal crias (January 1999 to May 2016) and 356 neonatal foals (February 2001 to May 2016) under 4-week-old were admitted to a university hospital. Methods: All data are presented descriptively and compared between groups using univariate and multivariate analyses. Results: Female crias (142/246, 57.7%) were significantly overrepresented in comparison to fillies (132/352, 37.5%). Congenital defects and transfer failure of passive immunity were more often observed in neonatal crias, while colic, diarrhea, patent urachus, septic arthritis, and omphalitis were significantly more common in CI foals. Overall survival to discharge (excluding fatal congenital defects) was comparable between crias (174/224; 77.8%) and foals (287/347, 82.1%), while crias (26/48; 54.2%) were more likely than foals (21/60; 35%) to die naturally than undergo euthanasia. Lower respiratory disease and indications for oxygen or IV glucose support increased mortality in the multivariate outcome models of both species. Species-specific adaptations of pediatric diagnostic criteria for sepsis were significantly associated with mortality in the multivariate analysis of patients with complete hematological datasets. However, the diagnosis of systemic inflammatory response syndrome (SIRS) did not retain statistical significance as an independent outcome predictor. Conclusions: Lower respiratory disease and oxygen or glucose dysregulation increased mortality irrespective of species. However, despite species-specific differences in disease prevalence, the success of intensive care management was comparable.
© Veterinary Emergency and Critical Care Society 2021.
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Publication Date: 2021-07-29 PubMed ID: 34324773DOI: 10.1111/vec.13093Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research aimed to identify the differences in disease symptoms and mortality rates in critically ill newborn alpacas (crias) and horses (foals) under intensive care. It was found that while certain diseases were more prevalent depending on the species, the overall success of intensive care treatment was comparable regardless of these differences.

Research Methodology

  • The researchers conducted a comparative, retrospective evaluation of the clinical records of 246 critically ill crias and 356 neonatal foals, all under four weeks old, admitted to a University hospital from January 1999 to May 2016.
  • The data was presented descriptively and differences between groups were compared using univariate and multivariate analyses.

Results & Findings

  • There were significantly more female crias represented in the study than fillies (female foals).
  • Congenital defects and passive immunity transfer failure were more often observed in crias, while ailments like colic, diarrhea, patent urachus, septic arthritis, and omphalitis were significantly more common in foals.
  • Overall survival rates were comparable between crias and foals when excluding lethal congenital defects, with crias being more likely to die naturally than foals.
  • Lower respiratory diseases and need for oxygen or intravenous glucose support increased mortality in both species.
  • Species-specific adaptations of pediatric diagnostic criteria for sepsis were significantly associated with mortality in patients with complete hematological datasets.
  • However, the diagnosis of systemic inflammatory response syndrome (SIRS) did not retain statistical significance as an independent outcome predictor.

Conclusions

  • Lower respiratory disease and oxygen or glucose dysregulation increased the risk of mortality regardless of species.
  • Despite clear differences in disease prevalence between the species, the overall success rate of intensive care management between crias and foals was similar.

Cite This Article

APA
Bedenice D, Avila B, Paradis MR. (2021). Comparative evaluation of clinical findings and prognostic outcome parameters in hospitalized, critically ill neonatal foals and crias. J Vet Emerg Crit Care (San Antonio), 31(5), 619-628. https://doi.org/10.1111/vec.13093

Publication

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
ISSN: 1476-4431
NlmUniqueID: 101152804
Country: United States
Language: English
Volume: 31
Issue: 5
Pages: 619-628

Researcher Affiliations

Bedenice, Daniela
  • Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts.
Avila, Bailey
  • Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts.
Paradis, Mary Rose
  • Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts.

MeSH Terms

  • Animals
  • Animals, Newborn
  • Camelids, New World
  • Critical Illness
  • Female
  • Horse Diseases / epidemiology
  • Horses
  • Prognosis
  • Retrospective Studies
  • Sepsis / epidemiology
  • Sepsis / veterinary

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