Complications associated with administration of detomidine into the caudal epidural space in a horse.
Abstract: A 364-kg (800-lb) 15-month-old sexually intact cryptorchid male Quarter Horse was admitted to the veterinary teaching hospital for castration. The horse was placed in standing stocks, and a caudal epidural injection of 18 mg of detomidine hydrochloride (50 micrograms/kg [23 micrograms/lb] of body weight) was administered. Fifteen minutes after injection, the horse unexpectedly collapsed to the floor, first into sternal, and then into lateral, recumbency. Because the horse would not get up, the decision was made to perform the surgery with the horse under general anesthesia. The horse required little halothane to maintain a surgical plane of anesthesia for most of the duration of surgery. Recovery from anesthesia was prolonged. Care must be taken when anesthetizing horses that have received large doses of detomidine via caudal epidural injection.
Publication Date: 1998-08-26 PubMed ID: 9713535
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Summary
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The paper discusses a case where a quarter horse experienced complications after being injected with a large dose of the sedative detomidine in preparation for castration, resulting in the need for additional anaesthesia and extended recovery time.
Overview of the Case
- The subject of the paper is a 15-month-old male Quarter Horse that was admitted to the vet hospital for a castration procedure.
- To facilitate the surgery, the horse was given an epidural injection of detomidine hydrochloride, a sedative. The dosage was given based on the horse’s weight.
Complications Post-Injection
- 15 minutes after the detomidine injection, the horse unexpectedly collapsed, initially lying on its chest and then on its side.
- Due to the horse’s state of immobility, the veterinarians decided to move the surgery under general anesthesia.
- It was observed that the horse required a significantly smaller amount of halothane, a general anesthetic, to maintain the required level of unconsciousness for the surgery.
- The horse also experienced a prolonged recovery from the anesthesia.
Conclusion and Warning
- The paper concludes by advising caution when using large doses of detomidine via epidural injection in horses. The complications experienced by the horse in this case indicate that such a dosage may lead to unexpected effects like collapse and extended recovery times.
- This warning is of particular relevance to equine veterinarians and those managing anesthesia in large animals. It underscores the need for further research to understand the impact of detomidine hydrochloride dosage on different breeds and sizes of horses.
Cite This Article
APA
Wittern C, Hendrickson DA, Trumble T, Wagner A.
(1998).
Complications associated with administration of detomidine into the caudal epidural space in a horse.
J Am Vet Med Assoc, 213(4), 516-518.
Publication
Researcher Affiliations
- Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523, USA.
MeSH Terms
- Analgesics / administration & dosage
- Anesthesia, Epidural / veterinary
- Anesthetics, Inhalation / administration & dosage
- Animals
- Blood Pressure / drug effects
- Cryptorchidism / surgery
- Cryptorchidism / veterinary
- Dose-Response Relationship, Drug
- Halothane / administration & dosage
- Horse Diseases / surgery
- Horses / physiology
- Horses / surgery
- Hypnotics and Sedatives / administration & dosage
- Imidazoles / administration & dosage
- Injections, Epidural / veterinary
- Male
- Orchiectomy / veterinary
- Postoperative Period
- Time Factors
Citations
This article has been cited 1 times.- Hendrickson DA. A review of equine laparoscopy. ISRN Vet Sci 2012;2012:492650.
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