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Computed tomographic appearance of equine sinonasal neoplasia.

Abstract: The computed tomography (CT) features of tumors involving the nasal cavity and/or paranasal sinuses of 15 horses were reviewed. The 15 tumors included five neuroendocrine tumors/neuroblastomas, two undifferentiated carcinomas, two myxosarcomas, and one each of nasal adenocarcinoma, hemangiosarcoma, chondroblastic osteosarcoma, anaplastic sarcoma, myxoma, and ossifying fibroma. All tumors except the ossifying fibroma were iso- or hypoattenuating relative to masseter muscle. Thirteen of the fifteen tumors exhibited moderate or marked osteolysis of adjacent cortical bone and 14/15 were characterized by destructive changes of the nasal turbinates, nasal septum, and/or infraorbital canal. Ten horses had moderate or marked involvement of the cribriform plate and six had clear intracranial extension of the mass. CT features were compared to radiographic findings for 10 horses. A mass was observed in 10/10 radiographic studies and mass within the caudal maxillary sinus (7/8) and rostral maxillary sinus (6/7) was identified correctly in most horses. The radiographs were least sensitive for identifying masses within the sphenopalatine sinus (0/5), cranium (0/4), and retrobulbar space (1/7) compared to CT. The radiographs also underestimated potential features of malignancy, such as severity of osteolysis or osseous production. While radiographs are a useful screening tool for identification of sinonasal masses, CT provides greater information regarding mass extent, features of malignancy, and important prognostic indicators.
Publication Date: 2011-12-28 PubMed ID: 22211373DOI: 10.1111/j.1740-8261.2011.01913.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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This research investigates the key characteristics of tumors found in the nasal cavity or paranasal sinuses of horses using computed tomography (CT). The findings reveal that CT scans offer more comprehensive information on tumor extent, features of malignancy, and potential prognosis, proving to be more insightful than traditional radiography.

Methodology and Results

  • The study analyzed CT features of 15 tumors found in the nasal region of horses. These tumors comprised a variety of types, from neuroendocrine tumors to ossifying fibroma.
  • All tumors, apart from the ossifying fibroma, were iso- or hypoattenuating – meaning they either had equal or lower attenuation compared to the masseter muscle. Attenuation here refers to the reduction in intensity of the CT signal as it passes through the tumor.
  • The majority of tumors (13 out of 15) showcased moderate to severe osteolysis – the destruction or disappearance of bony tissue – of the surrounding cortical bone. Furthermore, fourteen out of the fifteen tumors resulted in significant damage to the nasal turbinates, nasal septum, and/or infraorbital canal.
  • Additional significant findings were that ten horses showed serious involvement of their cribriform plate – a sieve-like structure between the brain and the nasal cavity – and six showed clear evidence of the tumor extending into the cranial (brain) cavity.

Comparative Analysis: CT Scan Vs Radiographs

  • The CT features were compared with radiographic findings for ten horses. In all ten radiographic studies, a mass was observed. Moreover, mass within the caudal and rostral maxillary sinuses was correctly identified in most horses.
  • However, radiographs were not as successful in identifying masses within the sphenopalatine sinus, cranium, and retrobulbar space in comparison to CT scans. This suggests that CT scans might offer superior sensitivity in identifying such masses.
  • It was also noted that the radiographs generally underestimated the severity of osteolysis or osseous production, both of which are potential features of malignant tumors.

Conclusion

  • The study concludes that while radiographs can be useful in initial identification of sinonasal masses, CT scans provide a much higher level of detail regarding the extent of the mass, characteristics indicative of malignancy, and important prognostic indicators.
  • This indicates that CT scans can potentially play a more meaningful role in facilitating early and more accurate diagnosis leading to effective treatment strategies for horses suffering from sinonasal neoplasia – a condition where abnormal tissue growth occurs in the sinonasal tract.

Cite This Article

APA
Cissell DD, Wisner ER, Textor J, Mohr FC, Scrivani PV, Théon AP. (2011). Computed tomographic appearance of equine sinonasal neoplasia. Vet Radiol Ultrasound, 53(3), 245-251. https://doi.org/10.1111/j.1740-8261.2011.01913.x

Publication

ISSN: 1058-8183
NlmUniqueID: 9209635
Country: England
Language: English
Volume: 53
Issue: 3
Pages: 245-251

Researcher Affiliations

Cissell, Derek D
  • School of Veterinary Medicine, University of California, Davis, CA, USA. dcissell@vmth.ucdavis.edu
Wisner, Erik R
    Textor, Jamie
      Mohr, F Charles
        Scrivani, Peter V
          Théon, Alain P

            MeSH Terms

            • Animals
            • Horse Diseases / diagnostic imaging
            • Horses
            • Nose Neoplasms / diagnostic imaging
            • Nose Neoplasms / veterinary
            • Paranasal Sinus Neoplasms / diagnostic imaging
            • Paranasal Sinus Neoplasms / veterinary
            • Tomography, X-Ray Computed / veterinary

            Citations

            This article has been cited 11 times.
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