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Animals : an open access journal from MDPI2025; 15(9); 1245; doi: 10.3390/ani15091245

Could Mesquite (Prosopis juliflora) Help Control Gastrointestinal Parasites in Horses?

Abstract: Exploring new natural-origin antiparasitic alternatives is essential in addressing the resistance issues that have emerged due to the widespread use of chemical or synthetic antiparasitic compounds. This area remains relatively underexplored despite the increasing recognition of plants like (mesquite) for their antiparasitic properties and nutritional value as a high-protein animal feed. This review aims to investigate the antiparasitic potential of against gastrointestinal parasites in horses. The review incorporates sources from 2005 to 2024. It was found that various phytochemical compounds from , particularly alkaloids, have demonstrated significant antiparasitic activity. Alkaloids are the most studied group due to their antibacterial, antiparasitic, and cytotoxic properties. According to the literature, the phytochemicals produced by hold promise as a potential solution for combating gastrointestinal parasites in horses. However, while preliminary findings suggest promising results, in vivo studies are necessary to evaluate the precise antiparasitic efficacy of these compounds and to determine the appropriate IC50 doses of alkaloids in horses, as well as to assess potential toxicity and side effects associated with their use.
Publication Date: 2025-04-28 PubMed ID: 40362060DOI: 10.3390/ani15091245Google Scholar: Lookup
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Summary

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The article explores the potential of mesquite (Prosopis juliflora) in controlling gastrointestinal parasites in horses, highlighting its significant anti-parasitic activity.

Research Objective

  • The paper seeks to understand the anti-parasitic potential of mesquite (Prosopis juliflora) against gastrointestinal parasites in horses. The main focus is on the different phytochemicals available in mesquite, with a crucial emphasis on alkaloids, known for their antibacterial, anti-parasitic, and cytotoxic properties.

Research Methodology

  • Researchers carried out a comprehensive review of sources from 2005 to 2024. They focused on existing literature on mesquite and its antiparasitic properties.

Findings

  • The study uncovered that numerous phytochemical compounds from mesquite, especially alkaloids, have shown notable antiparasitic activity. Thus, the phytochemicals produced by mesquite could serve as a potential solution for treating gastrointestinal parasites in horses.

Future Research

  • Although the preliminary findings suggest promising results, the researchers stress the need for in vivo studies. These studies will evaluate the precise antiparasitic efficacy of these compounds, determine the appropriate IC50 doses of mesquite alkaloids in horses, and assess potential toxicity and side effects associated with their use. This highlights the preliminary nature of this research and the need for further exploration and validation of the findings.

Cite This Article

APA
Rodriguez Velazquez D, Forte L, Varela Guerrero JA, Díaz Alvarado T, Elghandour MMMY, Maggiolino A, De Palo P, Salem AZM. (2025). Could Mesquite (Prosopis juliflora) Help Control Gastrointestinal Parasites in Horses? Animals (Basel), 15(9), 1245. https://doi.org/10.3390/ani15091245

Publication

ISSN: 2076-2615
NlmUniqueID: 101635614
Country: Switzerland
Language: English
Volume: 15
Issue: 9
PII: 1245

Researcher Affiliations

Rodriguez Velazquez, Desiderio
  • Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca C.P. 50000, Estado de México, Mexico.
Forte, Lucrezia
  • Department of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.
Varela Guerrero, Jorge Antonio
  • Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca C.P. 50000, Estado de México, Mexico.
Díaz Alvarado, Tonantzin
  • Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca C.P. 50000, Estado de México, Mexico.
Elghandour, Mona M M Y
  • Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca C.P. 50000, Estado de México, Mexico.
Maggiolino, Aristide
  • Department of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.
De Palo, Pasquale
  • Department of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.
Salem, Abdelfattah Z M
  • Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca C.P. 50000, Estado de México, Mexico.
  • Dipartimento di Scienze del Suolo, della Pianta e degli Alimenti (Di.S.S.P.A.), Università degli Studi di Bari, Via Giovanni Amendola, 165/a, 70126 Bari, Italy.

Citations

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