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Home / Equine Research Bank / Animals (Basel) / Current Antimicrobial Use in Horses Undergoing Exploratory C...
Animals : an open access journal from MDPI2023; 13(9); 1433; doi: 10.3390/ani13091433

Current Antimicrobial Use in Horses Undergoing Exploratory Celiotomy: A Survey of Board-Certified Equine Specialists.

Abstract: In the past decade, there has been a considerable increase in the recognition of antimicrobial resistance in equine practice. The objective of this study was to survey the current clinical use of antimicrobials for a commonly performed surgical procedure (exploratory celiotomy) with the goal of understanding how recent literature and changes in microbial resistance patterns may have impacted antimicrobial selection practices. An electronic survey was distributed to veterinary professionals within the American College of Veterinary Internal Medicine (ACVIM) and the American College of Veterinary Surgery (ACVS). A total of 113 completed surveys were returned. Practitioners reported antimicrobials were most frequently given 30-60 min preoperatively (63.1%). Two antimicrobial classes were typically administered (95.5%), with gentamicin (98.2%) and potassium penicillin (74.3%) being the most common. Antimicrobials were typically not re-dosed intraoperatively (78.6%). Factors that affected overall treatment length postoperatively included resection (81.4%), bloodwork (75.2%), enterotomy (74.3%), fever (85.0%), incisional complications (76.1%), and thrombophlebitis (67.3%). The most common duration of antimicrobial use was 1-3 d for non-strangulating lesions (54.4% of cases) and inflammatory conditions such as enteritis or peritonitis (50.4%), and 3-5 d for strangulating lesions (63.7%). Peri-incisional and intra-abdominal antimicrobials were used by 24.8% and 11.5% of respondents, respectively. In summary, antimicrobial usage patterns were highly variable among practitioners and, at times, not concordant with current literature.
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Publication Date: 2023-04-22 PubMed ID: 37174470PubMed Central: PMC10177570DOI: 10.3390/ani13091433Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article investigates the current use of antimicrobials by board-certified equine specialists during a common surgical procedure on horses. The goal of this study is to understand how modern literature and changing antimicrobial resistance patterns might have influenced antimicrobial selection practices.

Objective and Methodology of the Study

  • The primary objective of the study was to analyze the clinical use of antimicrobials in a surgical procedure known as exploratory celiotomy. The researchers aimed to understand how advancements in the literature and changes in antimicrobial resistance patterns are influencing the choice of antimicrobials.
  • To gather the necessary data, the researchers distributed an electronic survey to veterinary professionals within the American College of Veterinary Internal Medicine (ACVIM) and the American College of Veterinary Surgery (ACVS).
  • The survey yielded a total of 113 completed responses from the practitioners.

Findings of the Study

  • The survey revealed that the veterinarians generally administer antimicrobials 30-60 min preoperatively (63.1% of the cases).
  • Two classes of antimicrobials, gentamicin (98.2%) and potassium penicillin (74.3%), were most commonly used.
  • The majority of the specialists did not re-dose the antimicrobials intraoperatively (78.6% of the cases).
  • Several factors influenced the total duration of treatment post-surgery, including resection (81.4%), bloodwork results (75.2%), enterotomy (74.3%), fever (85.0%), complications at the incision site (76.1%), and thrombophlebitis (67.3%).
  • The antimicrobials were typically used for 1-3 days for non-strangulating lesions (54.4% of cases) and inflammatory conditions (50.4%), and for 3-5 days for strangulating lesions (63.7%).
  • The use of peri-incisional and intra-abdominal antimicrobials was reported by 24.8% and 11.5% of the respondents, respectively.

Conclusion

  • The study concludes that antimicrobial usage patterns differ significantly among practitioners.
  • It was observed that in some cases, the usage was not consistent with current literature, indicating a potential gap in adopting new techniques and findings in the field.

Cite This Article

APA
Rockow M, Griffenhagen G, Landolt G, Hendrickson D, Pezzanite L. (2023). Current Antimicrobial Use in Horses Undergoing Exploratory Celiotomy: A Survey of Board-Certified Equine Specialists. Animals (Basel), 13(9), 1433. https://doi.org/10.3390/ani13091433

Publication

Animals : an open access journal from MDPI
ISSN: 2076-2615
NlmUniqueID: 101635614
Country: Switzerland
Language: English
Volume: 13
Issue: 9
PII: 1433

Researcher Affiliations

Rockow, Meagan
  • Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Griffenhagen, Gregg
  • Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Landolt, Gabriele
  • Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Hendrickson, Dean
  • Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Pezzanite, Lynn
  • Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.

Grant Funding

  • N/A / Colorado State University Young Investigator Grant in Companion Animal Studies

Conflict of Interest Statement

The authors declare no conflict of interest.

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Citations

This article has been cited 2 times.
  1. Crabtree NE, Capper AM, McKinnon LH, Epstein KL. Perioperative factors and outcomes associated with antimicrobial therapy duration in horses undergoing exploratory celiotomy. Can Vet J 2025 Jun;66(6):653-662.
    pubmed: 40510283
  2. Rockow M, Griffenhagen G, Landolt G, Hendrickson D, Pezzanite L. The Effects of Antimicrobial Protocols and Other Perioperative Factors on Postoperative Complications in Horses Undergoing Celiotomy: A Retrospective Analysis, 2008-2021. Animals (Basel) 2023 Nov 19;13(22).
    doi: 10.3390/ani13223573pubmed: 38003189google scholar: lookup
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