FREE SHIPPING over $40
OVER 9000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
Home / Equine Research Bank / Trends Parasitol / Drug resistance in nematodes of veterinary importance: a sta...
Trends in parasitology2004; 20(10); 477-481; doi: 10.1016/j.pt.2004.08.001

Drug resistance in nematodes of veterinary importance: a status report.

Abstract: Reports of drug resistance have been made in every livestock host and to every anthelmintic class. In some regions of world, the extremely high prevalence of multi-drug resistance (MDR) in nematodes of sheep and goats threatens the viability of small-ruminant industries. Resistance in nematodes of horses and cattle has not yet reached the levels seen in small ruminants, but evidence suggests that the problems of resistance, including MDR worms, are also increasing in these hosts. There is an urgent need to develop both novel non-chemical approaches for parasite control and molecular assays capable of detecting resistant worms.
Get Full Text
Publication Date: 2004-09-15 PubMed ID: 15363441DOI: 10.1016/j.pt.2004.08.001Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Journal Article
  • Review

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article centers on the problem of drug resistance in nematodes that affect livestock, specifically in Sheep, Goats, Horses, and Cattle. It discusses the prevalence of multi-drug resistance in regions worldwide that pose a threat to small-ruminant industries and the developing resistance in horse and cattle nematodes. The article calls for an urgent need to develop non-chemical approaches for parasite control and molecular assays that can detect drug-resistant worms.

Objective of the Research

  • The research aims to provide a status report on the resistance of nematodes to drugs utilized in veterinary settings. Nematodes, affecting every livestock host, have been reported to resist every class of anthelmintics – drugs that serve to treat infections caused by parasitic worms – which can have significant impacts on livestock management and production.

Drug Resistance in Various Species

  • The study underlines the severe problem of multi-drug resistance (MDR) in nematodes that affect sheep and goats, particularly in certain global regions. This level of resistance threatens the survival and the overall economic viability of small-ruminant industries, i.e., industries that primarily raise and manage sheep and goats.
  • Although drug resistance in nematodes affecting horses and cattle hasn’t reached the levels observed in sheep and goats, the article suggests that resistance is increasing in these livestock too – implying a potentially larger and more severe scope of the problem.

Need for Novel Approaches and Molecular Assays

  • The researchers stress upon the urgency to develop non-chemical means to control these parasites. This approach will aim to circumvent the current resistance demonstrated by the nematodes towards the generally employed drugs.
  • Another crucial aspect highlighted by the researchers is that of creating molecular assays or laboratory tests which can detect worms that are resistant to drugs. This would allow for more efficient management, treatment, and control of parasitic infections in livestock.

Cite This Article

APA
Kaplan RM. (2004). Drug resistance in nematodes of veterinary importance: a status report. Trends Parasitol, 20(10), 477-481. https://doi.org/10.1016/j.pt.2004.08.001

Publication

Trends in parasitology
ISSN: 1471-4922
NlmUniqueID: 100966034
Country: England
Language: English
Volume: 20
Issue: 10
Pages: 477-481

Researcher Affiliations

Kaplan, Ray M
  • Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA. rkaplan@vet.uga.edu

MeSH Terms

  • Animals
  • Animals, Domestic / parasitology
  • Antinematodal Agents / pharmacology
  • Antinematodal Agents / therapeutic use
  • Drug Resistance
  • Drug Resistance, Multiple
  • Humans
  • Nematoda / drug effects
  • Nematoda / genetics
  • Nematode Infections / drug therapy
  • Nematode Infections / veterinary
  • Parasitic Sensitivity Tests / veterinary

Citations

This article has been cited 295 times.
  1. Thorne JW, Redden R, Bowdridge SA, Becker GM, Stegemiller MR, Murdoch BM. Genome-Wide Analysis of Sheep Artificially or Naturally Infected with Gastrointestinal Nematodes.. Genes (Basel) 2023 Jun 26;14(7).
    doi: 10.3390/genes14071342pubmed: 37510248google scholar: lookup
  2. Wang T, Koukoulis TF, Vella LJ, Su H, Purnianto A, Nie S, Ang CS, Ma G, Korhonen PK, Taki AC, Williamson NA, Reid GE, Gasser RB. The Proteome and Lipidome of Extracellular Vesicles from Haemonchus contortus to Underpin Explorations of Host-Parasite Cross-Talk.. Int J Mol Sci 2023 Jun 30;24(13).
    doi: 10.3390/ijms241310955pubmed: 37446130google scholar: lookup
  3. Castilla Gómez de Agüero V, Valderas-García E, González Del Palacio L, Giráldez FJ, Balaña-Fouce R, Martínez-Valladares M. Secretory IgA as Biomarker for Gastrointestinal Nematodes Natural Infection in Different Breed Sheep.. Animals (Basel) 2023 Jul 4;13(13).
    doi: 10.3390/ani13132189pubmed: 37443987google scholar: lookup
  4. Wu F, Wei H, Chen X, Du Z, Huang Y, Shi H, Yang Y, Du A, Ma G. Fatty acid- and retinol-binding protein 6 does not control worm fatty acid content in Caenorhabditis elegans but might play a role in Haemonchus contortus parasitism.. Parasit Vectors 2023 Jul 10;16(1):230.
    doi: 10.1186/s13071-023-05836-8pubmed: 37430357google scholar: lookup
  5. Calvo-Urbano B, Léger E, Gabain I, De Dood CJ, Diouf ND, Borlase A, Rudge JW, Corstjens PLAM, Sène M, Van Dam GJ, Walker M, Webster JP. Sensitivity and specificity of human point-of-care circulating cathodic antigen (POC-CCA) test in African livestock for rapid diagnosis of schistosomiasis: A Bayesian latent class analysis.. PLoS Negl Trop Dis 2023 May;17(5):e0010739.
    doi: 10.1371/journal.pntd.0010739pubmed: 37216407google scholar: lookup
  6. Zhang X, Sicalo Gianechini L, Li K, Kaplan RM, Witola WH. Broad-Spectrum Inhibitors for Conserved Unique Phosphoethanolamine Methyltransferases in Parasitic Nematodes Possess Anthelmintic Efficacy.. Antimicrob Agents Chemother 2023 Jun 15;67(6):e0000823.
    doi: 10.1128/aac.00008-23pubmed: 37212658google scholar: lookup
  7. Rehborg EG, Wheeler NJ, Zamanian M. Mapping resistance-associated anthelmintic interactions in the model nematode Caenorhabditis elegans.. bioRxiv 2023 Apr 26;.
    doi: 10.1101/2023.04.26.538424pubmed: 37163071google scholar: lookup
  8. Miró MV, Costa-Júnior LM, Lloberas M, Cardozo P, Lanusse C, Virkel G, Lifschitz A. Phytochemicals in Gastrointestinal Nematode Control: Pharmacokinetic-Pharmacodynamic Evaluation of the Ivermectin plus Carvone Combination.. Animals (Basel) 2023 Apr 9;13(8).
    doi: 10.3390/ani13081287pubmed: 37106850google scholar: lookup
  9. Shaver AO, Wit J, Dilks CM, Crombie TA, Li H, Aroian RV, Andersen EC. Variation in anthelmintic responses are driven by genetic differences among diverse C. elegans wild strains.. PLoS Pathog 2023 Apr;19(4):e1011285.
    doi: 10.1371/journal.ppat.1011285pubmed: 37011090google scholar: lookup
  10. Leutenegger CM, Lozoya CE, Tereski J, Savard C, Ogeer J, Lallier R. Emergence of Ancylostoma caninum parasites with the benzimidazole resistance F167Y polymorphism in the US dog population.. Int J Parasitol Drugs Drug Resist 2023 Apr;21:131-140.
    doi: 10.1016/j.ijpddr.2023.01.001pubmed: 36958067google scholar: lookup
  11. Tchetan E, Azando EVB, Olounladé PA, Alowanou GG, Hounzangbé-Adoté SM. In vitro effects of tannin and extracts of Bridelia ferruginea and Mitragyna inermis on the exsheathment of infective larvae of Haemonchuscontortus.. Int J Vet Sci Med 2020;8(1):93-99.
    doi: 10.1080/23144599.2020.1837056pubmed: 36935902google scholar: lookup
  12. Liu Y, Wang X, Luo X, Wang R, Zhai B, Wang P, Li J, Yang X. Transcriptomics and Proteomics of Haemonchus contortus in Response to Ivermectin Treatment.. Animals (Basel) 2023 Mar 3;13(5).
    doi: 10.3390/ani13050919pubmed: 36899776google scholar: lookup
  13. Vande Velde F, Hektoen L, Phythian CJ, Rinaldi L, Bosco A, Hinney B, Gehringer M, Strube C, May K, Knubben-Schweizer G, Martins OMD, Mateus TL, Simion VE, Charlier J, Bartley DJ, Claerebout E. Understanding the uptake of diagnostics for sustainable gastrointestinal nematode control by European dairy cattle farmers: a multi-country cross-sectional study.. Parasite 2023;30:4.
    doi: 10.1051/parasite/2023002pubmed: 36762941google scholar: lookup
  14. Ahmed H, Kilinc SG, Celik F, Kesik HK, Simsek S, Ahmad KS, Afzal MS, Farrakh S, Safdar W, Pervaiz F, Liaqat S, Zhang J, Cao J. An Inventory of Anthelmintic Plants across the Globe.. Pathogens 2023 Jan 13;12(1).
    doi: 10.3390/pathogens12010131pubmed: 36678480google scholar: lookup
  15. Antunes MI, Lima MS, Stilwell G, Romeiras MI, Fragoso L, Madeira de Carvalho LM. Anthelmintic Efficacy in Sheep and Goats under Different Management and Deworming Systems in the Region of Lisbon and Tagus Valley, Portugal.. Pathogens 2022 Dec 1;11(12).
    doi: 10.3390/pathogens11121457pubmed: 36558791google scholar: lookup
  16. Bava R, Castagna F, Palma E, Musolino V, Carresi C, Cardamone A, Lupia C, Marrelli M, Conforti F, Roncada P, Musella V, Britti D. Phytochemical Profile of Foeniculum vulgare Subsp. piperitum Essential Oils and Evaluation of Acaricidal Efficacy against Varroa destructor in Apis mellifera by In Vitro and Semi-Field Fumigation Tests.. Vet Sci 2022 Dec 9;9(12).
    doi: 10.3390/vetsci9120684pubmed: 36548845google scholar: lookup
  17. Macdonald SL, Abbas G, Ghafar A, Gauci CG, Bauquier J, El-Hage C, Tennent-Brown B, Wilkes EJA, Beasley A, Jacobson C, Cudmore L, Carrigan P, Hurley J, Beveridge I, Hughes KJ, Nielsen MK, Jabbar A. Egg reappearance periods of anthelmintics against equine cyathostomins: The state of play revisited.. Int J Parasitol Drugs Drug Resist 2023 Apr;21:28-39.
    doi: 10.1016/j.ijpddr.2022.12.002pubmed: 36543048google scholar: lookup
  18. Osterman-Lind E, Hedberg Alm Y, Hassler H, Wilderoth H, Thorolfson H, Tydén E. Evaluation of Strategies to Reduce Equine Strongyle Infective Larvae on Pasture and Study of Larval Migration and Overwintering in a Nordic Climate.. Animals (Basel) 2022 Nov 10;12(22).
    doi: 10.3390/ani12223093pubmed: 36428321google scholar: lookup
  19. Dyer CEF, Clarke NE, Nguyen DN, Herath HMPD, Hii SF, Pickford R, Traub RJ, Vaz Nery S. Assessing the efficacy of albendazole against hookworm in Vietnam using quantitative PCR and sodium nitrate flotation.. PLoS Negl Trop Dis 2022 Oct;16(10):e0010767.
    doi: 10.1371/journal.pntd.0010767pubmed: 36315591google scholar: lookup
  20. Miró MV, Costa-Júnior LM, Alvarez LI, Lanusse C, Virkel G, Lifschitz A. Pharmacological characterization of geraniol in sheep and its potential use in the control of gastrointestinal nematodes.. Vet Anim Sci 2022 Dec;18:100269.
    doi: 10.1016/j.vas.2022.100269pubmed: 36147514google scholar: lookup
  21. Bedenice D, Resnick-Sousa J, Bookbinder L, Trautwein V, Creasey HN, Widmer G. The association between fecal microbiota, age and endoparasitism in adult alpacas.. PLoS One 2022;17(8):e0272556.
    doi: 10.1371/journal.pone.0272556pubmed: 36006927google scholar: lookup
  22. Baranova MV, Panova OA, Polukhina DN, Panova DS. Reduction of the nematode egg reappearance period in horses after anthelmintic therapy.. Vet World 2022 Jun;15(6):1530-1534.
    doi: 10.14202/vetworld.2022.1530-1534pubmed: 35993067google scholar: lookup
  23. Malsa J, Courtot É, Boisseau M, Dumont B, Gombault P, Kuzmina TA, Basiaga M, Lluch J, Annonay G, Dhorne-Pollet S, Mach N, Sutra JF, Wimel L, Dubois C, Guégnard F, Serreau D, Lespine A, Sallé G, Fleurance G. Effect of sainfoin (Onobrychis viciifolia) on cyathostomin eggs excretion, larval development, larval community structure and efficacy of ivermectin treatment in horses.. Parasitology 2022 Sep;149(11):1439-1449.
    doi: 10.1017/S0031182022000853pubmed: 35929352google scholar: lookup
  24. Mesmar J, Abdallah R, Badran A, Maresca M, Shaito A, Baydoun E. Ziziphus nummularia: A Comprehensive Review of Its Phytochemical Constituents and Pharmacological Properties.. Molecules 2022 Jun 30;27(13).
    doi: 10.3390/molecules27134240pubmed: 35807485google scholar: lookup
  25. Muchiut S, Fiel C, Lirón JP, Lloberas M, Ceriani C, Lorenzo R, Riva E, Bernat G, Cardozo P, Fernández S, Steffan P. Population replacement of benzimidazole-resistant Haemonchus contortus with susceptible strains: evidence of changes in the resistance status.. Parasitol Res 2022 Sep;121(9):2623-2632.
    doi: 10.1007/s00436-022-07582-9pubmed: 35779120google scholar: lookup
  26. Voigt K, Geiger M, Jäger MC, Knubben-Schweizer G, Strube C, Zablotski Y. Effectiveness of Anthelmintic Treatments in Small Ruminants in Germany.. Animals (Basel) 2022 Jun 9;12(12).
    doi: 10.3390/ani12121501pubmed: 35739838google scholar: lookup
  27. Laing R, Doyle SR, McIntyre J, Maitland K, Morrison A, Bartley DJ, Kaplan R, Chaudhry U, Sargison N, Tait A, Cotton JA, Britton C, Devaney E. Transcriptomic analyses implicate neuronal plasticity and chloride homeostasis in ivermectin resistance and response to treatment in a parasitic nematode.. PLoS Pathog 2022 Jun;18(6):e1010545.
    doi: 10.1371/journal.ppat.1010545pubmed: 35696434google scholar: lookup
  28. Thorne JW, Bowdridge SA, Murdoch BM, Redden RR. Response of Rambouillet Lambs to an Artificial Gastrointestinal Nematode Infection.. Animals (Basel) 2022 May 6;12(9).
    doi: 10.3390/ani12091199pubmed: 35565625google scholar: lookup
  29. Koltz AM, Civitello DJ, Becker DJ, Deem SL, Classen AT, Barton B, Brenn-White M, Johnson ZE, Kutz S, Malishev M, Preston DL, Vannatta JT, Penczykowski RM, Ezenwa VO. Sublethal effects of parasitism on ruminants can have cascading consequences for ecosystems.. Proc Natl Acad Sci U S A 2022 May 17;119(20):e2117381119.
    doi: 10.1073/pnas.2117381119pubmed: 35533278google scholar: lookup
  30. Attia MM, Soliman SM, Salaeh NMK, Salem HM, Alkafafy M, Saad AM, El-Saadony MT, El-Gameel SM. Evaluation of immune responses and oxidative stress in donkeys: Immunological studies provoked by Parascaris equorum infection.. Saudi J Biol Sci 2022 Apr;29(4):2173-2179.
    doi: 10.1016/j.sjbs.2021.11.044pubmed: 35531146google scholar: lookup
  31. Walker M, Freitas LT, Halder JB, Brack M, Keiser J, King CH, Levecke B, Ai-Lian Lim Y, Pieri O, Sow D, Stothard JR, Webster JP, Zhou XN, Terry RF, Guérin PJ, Basáñez MG. Improving anthelmintic treatment for schistosomiasis and soil-transmitted helminthiases through sharing and reuse of individual participant data.. Wellcome Open Res 2022;7:5.
    doi: 10.12688/wellcomeopenres.17468.1pubmed: 35493199google scholar: lookup
  32. Munguía B, Saldaña J, Nieves M, Melian ME, Ferrer M, Teixeira R, Porcal W, Manta E, Domínguez L. Sensitivity of Haemonchus contortus to anthelmintics using different in vitro screening assays: a comparative study.. Parasit Vectors 2022 Apr 12;15(1):129.
    doi: 10.1186/s13071-022-05253-3pubmed: 35413885google scholar: lookup
  33. Jamil M, Aleem MT, Shaukat A, Khan A, Mohsin M, Rehman TU, Abbas RZ, Saleemi MK, Khatoon A, Babar W, Yan R, Li K. Medicinal Plants as an Alternative to Control Poultry Parasitic Diseases.. Life (Basel) 2022 Mar 18;12(3).
    doi: 10.3390/life12030449pubmed: 35330200google scholar: lookup
  34. Wondimu A, Bayu Y. Anthelmintic Drug Resistance of Gastrointestinal Nematodes of Naturally Infected Goats in Haramaya, Ethiopia.. J Parasitol Res 2022;2022:4025902.
    doi: 10.1155/2022/4025902pubmed: 35083085google scholar: lookup
  35. Caudell M, Mangesho PE, Mwakapeje ER, Dorado-García A, Kabali E, Price C, OleNeselle M, Kimani T, Fasina FO. Narratives of veterinary drug use in northern Tanzania and consequences for drug stewardship strategies in low-income and middle-income countries.. BMJ Glob Health 2022 Jan;7(1).
    doi: 10.1136/bmjgh-2021-006958pubmed: 35058305google scholar: lookup
  36. Fissiha W, Kinde MZ. Anthelmintic Resistance and Its Mechanism: A Review.. Infect Drug Resist 2021;14:5403-5410.
    doi: 10.2147/IDR.S332378pubmed: 34938088google scholar: lookup
  37. Jayawardene KLTD, Palombo EA, Boag PR. Natural Products Are a Promising Source for Anthelmintic Drug Discovery.. Biomolecules 2021 Oct 4;11(10).
    doi: 10.3390/biom11101457pubmed: 34680090google scholar: lookup
  38. Potârniche AV, Mickiewicz M, Olah D, Cerbu C, Spînu M, Hari A, Györke A, Moroz A, Czopowicz M, Várady M, Kaba J. First Report of Anthelmintic Resistance in Gastrointestinal Nematodes in Goats in Romania.. Animals (Basel) 2021 Sep 22;11(10).
    doi: 10.3390/ani11102761pubmed: 34679782google scholar: lookup
  39. Lahat L, Ortiz JM, Tizzani P, Ibáñez B, Valera F, Moreno E, Espeso G, Ruiz de Ybáñez R. Are Anthelminthic Treatments of Captive Ruminants Necessary?. Vet Sci 2021 Oct 18;8(10).
    doi: 10.3390/vetsci8100240pubmed: 34679070google scholar: lookup
  40. Reslova N, Skorpikova L, Kyrianova IA, Vadlejch J, Höglund J, Skuce P, Kasny M. The identification and semi-quantitative assessment of gastrointestinal nematodes in faecal samples using multiplex real-time PCR assays.. Parasit Vectors 2021 Aug 9;14(1):391.
    doi: 10.1186/s13071-021-04882-4pubmed: 34372893google scholar: lookup
  41. Kļaviņa A, Keidāne D, Šukele R, Bandere D, Kovaļčuka L. Traditional Latvian herbal medicinal plants used to treat parasite infections of small ruminants: A review.. Vet World 2021 Jun;14(6):1548-1558.
    doi: 10.14202/vetworld.2021.1548-1558pubmed: 34316202google scholar: lookup
  42. Fakhrahmad F, Rakhshandehroo E, Ghaemi M. Molecular evidence on the emergence of benzimidazole resistance SNPs in field isolates of Marshallagia marshalli (Nematoda: Trichostrongylidae) in sheep.. J Parasit Dis 2021 Jun;45(2):435-440.
    doi: 10.1007/s12639-020-01319-0pubmed: 34295042google scholar: lookup
  43. Njom VS, Winks T, Diallo O, Lowe A, Behnke J, Dickman MJ, Duce I, Johnstone I, Buttle DJ. The effects of plant cysteine proteinases on the nematode cuticle.. Parasit Vectors 2021 Jun 5;14(1):302.
    doi: 10.1186/s13071-021-04800-8pubmed: 34090505google scholar: lookup
  44. Yan X, Liu M, He S, Tong T, Liu Y, Ding K, Deng H, Wang P. An epidemiological study of gastrointestinal nematode and Eimeria coccidia infections in different populations of Kazakh sheep.. PLoS One 2021;16(5):e0251307.
    doi: 10.1371/journal.pone.0251307pubmed: 34010315google scholar: lookup
  45. Rashidifard M, Ashrafi S, Claassens S, Thünen T, Fourie H. A Pilot Approach Investigating the Potential of Crop Rotation With Sainfoin to Reduce Meloidogyne enterolobii Infection of Maize Under Greenhouse Conditions.. Front Plant Sci 2021;12:659322.
    doi: 10.3389/fpls.2021.659322pubmed: 33936147google scholar: lookup
  46. Knox J, Joly N, Linossi EM, Carmona-Negrón JA, Jura N, Pintard L, Zuercher W, Roy PJ. A survey of the kinome pharmacopeia reveals multiple scaffolds and targets for the development of novel anthelmintics.. Sci Rep 2021 Apr 28;11(1):9161.
    doi: 10.1038/s41598-021-88150-6pubmed: 33911106google scholar: lookup
  47. Zanet S, Battisti E, Labate F, Oberto F, Ferroglio E. Reduced Efficacy of Fenbendazole and Pyrantel Pamoate Treatments against Intestinal Nematodes of Stud and Performance Horses.. Vet Sci 2021 Mar 5;8(3).
    doi: 10.3390/vetsci8030042pubmed: 33807857google scholar: lookup
  48. Rosa BA, Snowden C, Martin J, Fischer K, Kupritz J, Beshah E, Supali T, Gankpala L, Fischer PU, Urban JF Jr, Mitreva M. Whipworm-Associated Intestinal Microbiome Members Consistent Across Both Human and Mouse Hosts.. Front Cell Infect Microbiol 2021;11:637570.
    doi: 10.3389/fcimb.2021.637570pubmed: 33777847google scholar: lookup
  49. Elseadawy R, Abbas I, Al-Araby M, Abu-Elwafa S. Molecular identification of different Trichostrongylus species infecting sheep and goats from Dakahlia governorate, Egypt.. J Parasit Dis 2021 Mar;45(1):218-227.
    doi: 10.1007/s12639-020-01299-1pubmed: 33746407google scholar: lookup
  50. Motaher R, Grill E, McKean E, Kenney E, Eleftherianos I, Hawdon JM, O'Halloran DM. Chemogenomic approach to identifying nematode chemoreceptor drug targets in the entomopathogenic nematode Heterorhabditis bacteriophora.. Comput Biol Chem 2021 Jun;92:107464.
    doi: 10.1016/j.compbiolchem.2021.107464pubmed: 33667976google scholar: lookup
  51. Cheong MC, Wang Z, Jaleta TG, Li X, Lok JB, Kliewer SA, Mangelsdorf DJ. Identification of a nuclear receptor/coactivator developmental signaling pathway in the nematode parasite Strongyloides stercoralis.. Proc Natl Acad Sci U S A 2021 Feb 23;118(8).
    doi: 10.1073/pnas.2021864118pubmed: 33602820google scholar: lookup
  52. Miró MV, Luque S, Cardozo P, Lloberas M, Sousa DM, Soares AMS, Costa-Junior LM, Virkel GL, Lifschitz AL. Plant-Derived Compounds as a Tool for the Control of Gastrointestinal Nematodes: Modulation of Abamectin Pharmacological Action by Carvone.. Front Vet Sci 2020;7:601750.
    doi: 10.3389/fvets.2020.601750pubmed: 33392294google scholar: lookup
  53. Goel V, Kaur P, Singla LD, Choudhury D. Biomedical Evaluation of Lansium parasiticum Extract-Protected Silver Nanoparticles Against Haemonchus contortus, a Parasitic Worm.. Front Mol Biosci 2020;7:595646.
    doi: 10.3389/fmolb.2020.595646pubmed: 33392256google scholar: lookup
  54. Neff E, Evans CC, Jimenez Castro PD, Kaplan RM, Dharmarajan G. Drug Resistance in Filarial Parasites Does Not Affect Mosquito Vectorial Capacity.. Pathogens 2020 Dec 22;10(1).
    doi: 10.3390/pathogens10010002pubmed: 33375024google scholar: lookup
  55. Li H, Abraham A, Gazzola D, Hu Y, Beamer G, Flanagan K, Soto E, Rus F, Mirza Z, Draper A, Vakalapudi S, Stockman C, Bain P, Urban JF Jr, Ostroff GR, Aroian RV. Recombinant Paraprobiotics as a New Paradigm for Treating Gastrointestinal Nematode Parasites of Humans.. Antimicrob Agents Chemother 2021 Feb 17;65(3).
    doi: 10.1128/AAC.01469-20pubmed: 33318013google scholar: lookup
  56. Wit J, Dilks CM, Andersen EC. Complementary Approaches with Free-living and Parasitic Nematodes to Understanding Anthelmintic Resistance.. Trends Parasitol 2021 Mar;37(3):240-250.
    doi: 10.1016/j.pt.2020.11.008pubmed: 33317926google scholar: lookup
  57. Kotze AC, Gilleard JS, Doyle SR, Prichard RK. Challenges and opportunities for the adoption of molecular diagnostics for anthelmintic resistance.. Int J Parasitol Drugs Drug Resist 2020 Dec;14:264-273.
    doi: 10.1016/j.ijpddr.2020.11.005pubmed: 33307336google scholar: lookup
  58. Hahnel SR, Dilks CM, Heisler I, Andersen EC, Kulke D. Caenorhabditis elegans in anthelmintic research - Old model, new perspectives.. Int J Parasitol Drugs Drug Resist 2020 Dec;14:237-248.
    doi: 10.1016/j.ijpddr.2020.09.005pubmed: 33249235google scholar: lookup
  59. Sanders J, Xie Y, Gazzola D, Li H, Abraham A, Flanagan K, Rus F, Miller M, Hu Y, Guynn S, Draper A, Vakalapudi S, Petersson KH, Zarlenga D, Li RW, Urban JF Jr, Ostroff GR, Zajac A, Aroian RV. A new paraprobiotic-based treatment for control of Haemonchus contortus in sheep.. Int J Parasitol Drugs Drug Resist 2020 Dec;14:230-236.
    doi: 10.1016/j.ijpddr.2020.11.004pubmed: 33242790google scholar: lookup
  60. Palevich N, Maclean PH, Choi YJ, Mitreva M. Characterization of the Complete Mitochondrial Genomes of Two Sibling Species of Parasitic Roundworms, Haemonchus contortus and Teladorsagia circumcincta.. Front Genet 2020;11:573395.
    doi: 10.3389/fgene.2020.573395pubmed: 33133162google scholar: lookup
  61. Saleh S, Abbas I, Al-Araby M, Hildreth M, Abu-Elwafa S. Combined Molecular and Lectin Binding Assays to Identify Different Trichostrongyle Eggs in Feces of Sheep and Goats from Egypt.. Acta Parasitol 2021 Jun;66(2):384-396.
    doi: 10.1007/s11686-020-00287-ypubmed: 33034823google scholar: lookup
  62. Fesseha H, Mathewos M, Kidanemariam F. Anthelmintic Efficacy of Strongyle Nematodes to Ivermectin and Fenbendazole on Working Donkeys (Equus asinus) in and around Hosaena Town, Southern Ethiopia.. Vet Med Int 2020;2020:4868797.
    doi: 10.1155/2020/4868797pubmed: 33029340google scholar: lookup
  63. Schwarz K, Bapst B, Holinger M, Thüer S, Schleip I, Werne S. Potentials of using milk performance data and FAMACHA score as indicators for Targeted Selective Treatment in Lacaune dairy sheep in Switzerland.. Vet Parasitol X 2020 Dec;4:100030.
    doi: 10.1016/j.vpoa.2020.100030pubmed: 32984809google scholar: lookup
  64. Hu G, Do DN, Gray J, Miar Y. Selection for Favorable Health Traits: A Potential Approach to Cope with Diseases in Farm Animals.. Animals (Basel) 2020 Sep 22;10(9).
    doi: 10.3390/ani10091717pubmed: 32971980google scholar: lookup
  65. Ehsan M, Hu RS, Liang QL, Hou JL, Song X, Yan R, Zhu XQ, Li X. Advances in the Development of Anti-Haemonchus contortus Vaccines: Challenges, Opportunities, and Perspectives.. Vaccines (Basel) 2020 Sep 22;8(3).
    doi: 10.3390/vaccines8030555pubmed: 32971770google scholar: lookup
  66. Gerhard AP, Krücken J, Heitlinger E, Janssen IJI, Basiaga M, Kornaś S, Beier C, Nielsen MK, Davis RE, Wang J, von Samson-Himmelstjerna G. The P-glycoprotein repertoire of the equine parasitic nematode Parascaris univalens.. Sci Rep 2020 Aug 12;10(1):13586.
    doi: 10.1038/s41598-020-70529-6pubmed: 32788636google scholar: lookup
  67. Dusabimana A, Bhwana D, Raimon S, Mmbando BP, Hotterbeekx A, Tepage F, Mandro M, Siewe Fodjo JN, Abrams S, Colebunders R. Ivermectin Treatment Response in Onchocerca Volvulus Infected Persons with Epilepsy: A Three-Country Short Cohort Study.. Pathogens 2020 Jul 29;9(8).
    doi: 10.3390/pathogens9080617pubmed: 32751060google scholar: lookup
  68. Tyson F, Dalesman S, Brophy PM, Morphew RM. Novel Equine Faecal Egg Diagnostics: Validation of the FECPAK(G2).. Animals (Basel) 2020 Jul 23;10(8).
    doi: 10.3390/ani10081254pubmed: 32717982google scholar: lookup
  69. Kelleher AC, Good B, de Waal T, Keane OM. Anthelmintic resistance among gastrointestinal nematodes of cattle on dairy calf to beef farms in Ireland.. Ir Vet J 2020;73:12.
    doi: 10.1186/s13620-020-00167-xpubmed: 32637072google scholar: lookup
  70. Mirza Z, Soto ER, Hu Y, Nguyen TT, Koch D, Aroian RV, Ostroff GR. Anthelmintic Activity of Yeast Particle-Encapsulated Terpenes.. Molecules 2020 Jun 27;25(13).
    doi: 10.3390/molecules25132958pubmed: 32605043google scholar: lookup
  71. Elghryani N, Crispell J, Ebrahimi R, Krivoruchko M, Lobaskin V, McOwan T, O'Connor W, Power E, Voisin B, Scholz D, de Waal T. Preliminary evaluation of a novel, fully automated, Telenostic device for rapid field-diagnosis of cattle parasites.. Parasitology 2020 Sep;147(11):1249-1253.
    doi: 10.1017/S0031182020001031pubmed: 32576299google scholar: lookup
  72. Jimenez Castro PD, Mansour A, Charles S, Hostetler J, Settje T, Kulke D, Kaplan RM. Efficacy evaluation of anthelmintic products against an infection with the canine hookworm (Ancylostoma caninum) isolate Worthy 4.1F3P in dogs.. Int J Parasitol Drugs Drug Resist 2020 Aug;13:22-27.
    doi: 10.1016/j.ijpddr.2020.04.003pubmed: 32403053google scholar: lookup
  73. Arsenopoulos K, Minoudi S, Symeonidou I, Triantafyllidis A, Katsafadou AI, Lianou DT, Fthenakis GC, Papadopoulos E. Frequency of Resistance to Benzimidazoles of Haemonchus contortus Helminths from Dairy Sheep, Goats, Cattle and Buffaloes in Greece.. Pathogens 2020 May 3;9(5).
    doi: 10.3390/pathogens9050347pubmed: 32375252google scholar: lookup
  74. Vlaminck J, Cools P, Albonico M, Ame S, Chanthapaseuth T, Viengxay V, Do Trung D, Osei-Atweneboana MY, Asuming-Brempong E, Jahirul Karim M, Al Kawsar A, Keiser J, Khieu V, Faye B, Turate I, Mbonigaba JB, Ruijeni N, Shema E, Luciañez A, Santiago Nicholls R, Jamsheed M, Mikhailova A, Montresor A, Mupfasoni D, Yajima A, Ngina Mwinzi P, Gilleard J, Prichard RK, Verweij JJ, Vercruysse J, Levecke B. Piloting a surveillance system to monitor the global patterns of drug efficacy and the emergence of anthelmintic resistance in soil-transmitted helminth control programs: a Starworms study protocol.. Gates Open Res 2020;4:28.
    doi: 10.12688/gatesopenres.13115.1pubmed: 32266328google scholar: lookup
  75. Khan S, Nisar A, Yuan J, Luo X, Dou X, Liu F, Zhao X, Li J, Ahmad H, Mehmood SA, Feng X. A Whole Genome Re-Sequencing Based GWA Analysis Reveals Candidate Genes Associated with Ivermectin Resistance in Haemonchus contortus.. Genes (Basel) 2020 Mar 28;11(4).
    doi: 10.3390/genes11040367pubmed: 32231078google scholar: lookup
  76. Naqvi MA, Li H, Gao W, Naqvi SZ, Jamil T, Aimulajiang K, Xu L, Song X, Li X, Yan R. Haemonchus contortus: siRNA mediated knockdown of matrix metalloproteinase 12A (MMP-12) results in reduction of infectivity.. Parasit Vectors 2020 Mar 24;13(1):151.
    doi: 10.1186/s13071-020-04025-1pubmed: 32204731google scholar: lookup
  77. Scare JA, Dini P, Norris JK, Steuer AE, Scoggin K, Gravatte HS, Howe DK, Slusarewicz P, Nielsen MK. Ascarids exposed: a method for in vitro drug exposure and gene expression analysis of anthelmintic naïve Parascaris spp.. Parasitology 2020 May;147(6):659-666.
    doi: 10.1017/S0031182020000189pubmed: 32046800google scholar: lookup
  78. Hedtke SM, Kuesel AC, Crawford KE, Graves PM, Boussinesq M, Lau CL, Boakye DA, Grant WN. Genomic Epidemiology in Filarial Nematodes: Transforming the Basis for Elimination Program Decisions.. Front Genet 2019;10:1282.
    doi: 10.3389/fgene.2019.01282pubmed: 31998356google scholar: lookup
  79. Tinkler SH. Preventive chemotherapy and anthelmintic resistance of soil-transmitted helminths - Can we learn nothing from veterinary medicine?. One Health 2020 Jun;9:100106.
    doi: 10.1016/j.onehlt.2019.100106pubmed: 31956691google scholar: lookup
  80. Santos LL, Salgado JA, Drummond MG, Bastianetto E, Santos CP, Brasil BSAF, Taconeli CA, Oliveira DAA. Molecular method for the semiquantitative identification of gastrointestinal nematodes in domestic ruminants.. Parasitol Res 2020 Feb;119(2):529-543.
    doi: 10.1007/s00436-019-06569-3pubmed: 31834492google scholar: lookup
  81. Jimenez Castro PD, Howell SB, Schaefer JJ, Avramenko RW, Gilleard JS, Kaplan RM. Multiple drug resistance in the canine hookworm Ancylostoma caninum: an emerging threat?. Parasit Vectors 2019 Dec 9;12(1):576.
    doi: 10.1186/s13071-019-3828-6pubmed: 31818311google scholar: lookup
  82. Malekpour SH, Rakhshandehroo E, Yektaseresht A. Molecular characterization of β-tubulin gene associated with benzimidazole resistance in larvae of field isolates of Parascaris (Nematoda: Ascarididae).. J Parasit Dis 2019 Dec;43(4):672-678.
    doi: 10.1007/s12639-019-01146-ypubmed: 31749539google scholar: lookup
  83. Turnbull F, Devaney E, Morrison AA, Laing R, Bartley DJ. Genotypic characterisation of monepantel resistance in historical and newly derived field strains of Teladorsagia circumcincta.. Int J Parasitol Drugs Drug Resist 2019 Dec;11:59-69.
    doi: 10.1016/j.ijpddr.2019.10.002pubmed: 31622822google scholar: lookup
  84. Stasiuk SJ, MacNevin G, Workentine ML, Gray D, Redman E, Bartley D, Morrison A, Sharma N, Colwell D, Ro DK, Gilleard JS. Similarities and differences in the biotransformation and transcriptomic responses of Caenorhabditis elegans and Haemonchus contortus to five different benzimidazole drugs.. Int J Parasitol Drugs Drug Resist 2019 Dec;11:13-29.
    doi: 10.1016/j.ijpddr.2019.09.001pubmed: 31542693google scholar: lookup
  85. Estrada-Reyes ZM, Rae O, Postley C, Jiménez Medrano MB, Leal Gutiérrez JD, Mateescu RG. Association study reveals Th17, Treg, and Th2 loci related to resistance to Haemonchus contortus in Florida Native sheep1.. J Anim Sci 2019 Nov 4;97(11):4428-4444.
    doi: 10.1093/jas/skz299pubmed: 31541548google scholar: lookup
  86. Choudhary S, Tipton JG, Abongwa M, Brewer MT, Chelladurai JJ, Musselman N, Martin RJ, Robertson AP. Pharmacological characterization of a homomeric nicotinic acetylcholine receptor formed by Ancylostoma caninum ACR-16.. Invert Neurosci 2019 Sep 5;19(4):11.
    doi: 10.1007/s10158-019-0231-0pubmed: 31486912google scholar: lookup
  87. Elfawal MA, Savinov SN, Aroian RV. Drug Screening for Discovery of Broad-spectrum Agents for Soil-transmitted Nematodes.. Sci Rep 2019 Aug 26;9(1):12347.
    doi: 10.1038/s41598-019-48720-1pubmed: 31451730google scholar: lookup
  88. Sargison ND, MacLeay M, Morrison AA, Bartley DJ, Evans M, Chaudhry U. Development of amplicon sequencing for the analysis of benzimidazole resistance allele frequencies in field populations of gastrointestinal nematodes.. Int J Parasitol Drugs Drug Resist 2019 Aug;10:92-100.
    doi: 10.1016/j.ijpddr.2019.08.003pubmed: 31425900google scholar: lookup
  89. Jasmer DP, Rosa BA, Tyagi R, Mitreva M. Omics Driven Understanding of the Intestines of Parasitic Nematodes.. Front Genet 2019;10:652.
    doi: 10.3389/fgene.2019.00652pubmed: 31402928google scholar: lookup
  90. Makun HJ, Abdulganiyu KA, Shaibu S, Otaru SM, Okubanjo OO, Kudi CA, Notter DR. Phenotypic resistance of indigenous goat breeds to infection with Haemonchus contortus in northwestern Nigeria.. Trop Anim Health Prod 2020 Jan;52(1):79-87.
    doi: 10.1007/s11250-019-01987-ypubmed: 31317356google scholar: lookup
  91. Al Kalaldeh M, Gibson J, Lee SH, Gondro C, van der Werf JHJ. Detection of genomic regions underlying resistance to gastrointestinal parasites in Australian sheep.. Genet Sel Evol 2019 Jul 3;51(1):37.
    doi: 10.1186/s12711-019-0479-1pubmed: 31269896google scholar: lookup
  92. Hogan G, Walker S, Turnbull F, Curiao T, Morrison AA, Flores Y, Andrews L, Claesson MJ, Tangney M, Bartley DJ. Microbiome analysis as a platform R&D tool for parasitic nematode disease management.. ISME J 2019 Nov;13(11):2664-2680.
    doi: 10.1038/s41396-019-0462-4pubmed: 31239540google scholar: lookup
  93. Kumar R. Molecular markers and their application in the monitoring of acaricide resistance in Rhipicephalus microplus.. Exp Appl Acarol 2019 Jun;78(2):149-172.
    doi: 10.1007/s10493-019-00394-0pubmed: 31190248google scholar: lookup
  94. Wang S, Hu D, Wang C, Tang X, Du M, Gu X, Suo J, Hu M, Fang R, Zhu X, Zhang X, Du A, Suo X, Liu X. Transcriptional profiling of innate immune responses in sheep PBMCs induced by Haemonchus contortus soluble extracts.. Parasit Vectors 2019 Apr 25;12(1):182.
    doi: 10.1186/s13071-019-3441-8pubmed: 31023355google scholar: lookup
  95. Schuster KD, Mohammadi M, Cahill KB, Matte SL, Maillet AD, Vashisth H, Cote RH. Pharmacological and molecular dynamics analyses of differences in inhibitor binding to human and nematode PDE4: Implications for management of parasitic nematodes.. PLoS One 2019;14(3):e0214554.
    doi: 10.1371/journal.pone.0214554pubmed: 30917179google scholar: lookup
  96. Cupp EW, Mackenzie CD, Unnasch TR. Importance of ivermectin to human onchocerciasis: past, present, and the future.. Res Rep Trop Med 2011;2:81-92.
    doi: 10.2147/RRTM.S19477pubmed: 30881181google scholar: lookup
  97. Chen J, Ma F, Li X, Zhao R, Yang X. Effect of norepinephrine treatment on Haemonchus contortus and its excretory products.. Parasitol Res 2019 Apr;118(4):1239-1248.
    doi: 10.1007/s00436-019-06230-zpubmed: 30788574google scholar: lookup
  98. Idris OA, Wintola OA, Afolayan AJ. Helminthiases; prevalence, transmission, host-parasite interactions, resistance to common synthetic drugs and treatment.. Heliyon 2019 Jan;5(1):e01161.
    doi: 10.1016/j.heliyon.2019.e01161pubmed: 30775568google scholar: lookup
  99. Kitchen S, Ratnappan R, Han S, Leasure C, Grill E, Iqbal Z, Granger O, O'Halloran DM, Hawdon JM. Isolation and characterization of a naturally occurring multidrug-resistant strain of the canine hookworm, Ancylostoma caninum.. Int J Parasitol 2019 Apr;49(5):397-406.
    doi: 10.1016/j.ijpara.2018.12.004pubmed: 30771359google scholar: lookup
  100. Ménez C, Alberich M, Courtot E, Guegnard F, Blanchard A, Aguilaniu H, Lespine A. The transcription factor NHR-8: A new target to increase ivermectin efficacy in nematodes.. PLoS Pathog 2019 Feb;15(2):e1007598.
    doi: 10.1371/journal.ppat.1007598pubmed: 30759156google scholar: lookup
  101. Charvet CL, Guégnard F, Courtot E, Cortet J, Neveu C. Nicotine-sensitive acetylcholine receptors are relevant pharmacological targets for the control of multidrug resistant parasitic nematodes.. Int J Parasitol Drugs Drug Resist 2018 Dec;8(3):540-549.
    doi: 10.1016/j.ijpddr.2018.11.003pubmed: 30502120google scholar: lookup
  102. Vlaminck J, Cools P, Albonico M, Ame S, Ayana M, Bethony J, Cringoli G, Dana D, Keiser J, Maurelli MP, Montresor A, Mekonnen Z, Mirams G, Corrêa-Oliveira R, Prichard R, Rashwan N, Rinaldi L, Sayasone S, Thomas E, Verweij JJ, Vercruysse J, Levecke B. Comprehensive evaluation of stool-based diagnostic methods and benzimidazole resistance markers to assess drug efficacy and detect the emergence of anthelmintic resistance: A Starworms study protocol.. PLoS Negl Trop Dis 2018 Nov;12(11):e0006912.
    doi: 10.1371/journal.pntd.0006912pubmed: 30388108google scholar: lookup
  103. Vande Velde F, Charlier J, Claerebout E. Farmer Behavior and Gastrointestinal Nematodes in Ruminant Livestock-Uptake of Sustainable Control Approaches.. Front Vet Sci 2018;5:255.
    doi: 10.3389/fvets.2018.00255pubmed: 30386785google scholar: lookup
  104. Somarathne MBCL, Gunawardene YINS, Chandrasekharan NV, Ellepola ANB, Dassanayake RS. Functional analysis of a novel parasitic nematode-specific protein of Setaria digitata larvae in Culex quinquefasciatus by siRNA mediated RNA interference.. Parasit Vectors 2018 Oct 10;11(1):541.
    doi: 10.1186/s13071-018-3096-xpubmed: 30314510google scholar: lookup
  105. Peña-Espinoza M, Valente AH, Thamsborg SM, Simonsen HT, Boas U, Enemark HL, López-Muñoz R, Williams AR. Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review.. Parasit Vectors 2018 Aug 22;11(1):475.
    doi: 10.1186/s13071-018-3012-4pubmed: 30134991google scholar: lookup
  106. Caminade C, McIntyre KM, Jones AE. Impact of recent and future climate change on vector-borne diseases.. Ann N Y Acad Sci 2019 Jan;1436(1):157-173.
    doi: 10.1111/nyas.13950pubmed: 30120891google scholar: lookup
  107. Raza A, Rand J, Qamar AG, Jabbar A, Kopp S. Gastrointestinal Parasites in Shelter Dogs: Occurrence, Pathology, Treatment and Risk to Shelter Workers.. Animals (Basel) 2018 Jul 2;8(7).
    doi: 10.3390/ani8070108pubmed: 30004469google scholar: lookup
  108. Bekelaar K, Waghorn T, Tavendale M, McKenzie C, Leathwick D. Heat shock, but not temperature, is a biological trigger for the exsheathment of third-stage larvae of Haemonchus contortus.. Parasitol Res 2018 Aug;117(8):2395-2402.
    doi: 10.1007/s00436-018-5927-2pubmed: 29785617google scholar: lookup
  109. Hu Y, Miller M, Zhang B, Nguyen TT, Nielsen MK, Aroian RV. In vivo and in vitro studies of Cry5B and nicotinic acetylcholine receptor agonist anthelmintics reveal a powerful and unique combination therapy against intestinal nematode parasites.. PLoS Negl Trop Dis 2018 May;12(5):e0006506.
    doi: 10.1371/journal.pntd.0006506pubmed: 29775454google scholar: lookup
  110. Hu Y, Nguyen TT, Lee ACY, Urban JF Jr, Miller MM, Zhan B, Koch DJ, Noon JB, Abraham A, Fujiwara RT, Bowman DD, Ostroff GR, Aroian RV. Bacillus thuringiensis Cry5B protein as a new pan-hookworm cure.. Int J Parasitol Drugs Drug Resist 2018 Aug;8(2):287-294.
    doi: 10.1016/j.ijpddr.2018.05.001pubmed: 29772478google scholar: lookup
  111. Elmahalawy ST, Halvarsson P, Skarin M, Höglund J. Genetic variants in dyf-7 validated by droplet digital PCR are not drivers for ivermectin resistance in Haemonchus contortus.. Int J Parasitol Drugs Drug Resist 2018 Aug;8(2):278-286.
    doi: 10.1016/j.ijpddr.2018.04.005pubmed: 29758488google scholar: lookup
  112. Blanchard A, Guégnard F, Charvet CL, Crisford A, Courtot E, Sauvé C, Harmache A, Duguet T, O'Connor V, Castagnone-Sereno P, Reaves B, Wolstenholme AJ, Beech RN, Holden-Dye L, Neveu C. Deciphering the molecular determinants of cholinergic anthelmintic sensitivity in nematodes: When novel functional validation approaches highlight major differences between the model Caenorhabditis elegans and parasitic species.. PLoS Pathog 2018 May;14(5):e1006996.
    doi: 10.1371/journal.ppat.1006996pubmed: 29719008google scholar: lookup
  113. Borlase A, Webster JP, Rudge JW. Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa.. Evol Appl 2018 Apr;11(4):501-515.
    doi: 10.1111/eva.12529pubmed: 29636802google scholar: lookup
  114. Wang T, Xie Y, Zheng Y, Wang C, Li D, Koehler AV, Gasser RB. Parasites of the Giant Panda: A Risk Factor in the Conservation of a Species.. Adv Parasitol 2018;99:1-33.
    doi: 10.1016/bs.apar.2017.12.003pubmed: 29530307google scholar: lookup
  115. Vijaya, Yadav AK, Gogoi S. In vitro and in vivo anthelmintic efficacy of two pentacyclic triterpenoids, ursolic acid and betulinic acid against mice pinworm, Syphacia obvelata.. J Parasit Dis 2018 Mar;42(1):144-149.
    doi: 10.1007/s12639-017-0960-0pubmed: 29491574google scholar: lookup
  116. Rosa BA, Supali T, Gankpala L, Djuardi Y, Sartono E, Zhou Y, Fischer K, Martin J, Tyagi R, Bolay FK, Fischer PU, Yazdanbakhsh M, Mitreva M. Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia.. Microbiome 2018 Feb 28;6(1):33.
    doi: 10.1186/s40168-018-0416-5pubmed: 29486796google scholar: lookup
  117. Abongwa M, Martin RJ, Robertson AP. A BRIEF REVIEW ON THE MODE OF ACTION OF ANTINEMATODAL DRUGS.. Acta Vet (Beogr) 2017 Jun;67(2):137-152.
    doi: 10.1515/acve-2017-0013pubmed: 29416226google scholar: lookup
  118. Turnbull F, Jonsson NN, Kenyon F, Skuce PJ, Bisset SA. P-glycoprotein-9 and macrocyclic lactone resistance status in selected strains of the ovine gastrointestinal nematode, Teladorsagia circumcincta.. Int J Parasitol Drugs Drug Resist 2018 Apr;8(1):70-80.
    doi: 10.1016/j.ijpddr.2018.01.004pubmed: 29414109google scholar: lookup
  119. Shepherd C, Wangchuk P, Loukas A. Of dogs and hookworms: man's best friend and his parasites as a model for translational biomedical research.. Parasit Vectors 2018 Jan 25;11(1):59.
    doi: 10.1186/s13071-018-2621-2pubmed: 29370855google scholar: lookup
  120. George MM, Lopez-Soberal L, Storey BE, Howell SB, Kaplan RM. Motility in the L3 stage is a poor phenotype for detecting and measuring resistance to avermectin/milbemycin drugs in gastrointestinal nematodes of livestock.. Int J Parasitol Drugs Drug Resist 2018 Apr;8(1):22-30.
    doi: 10.1016/j.ijpddr.2017.12.002pubmed: 29274827google scholar: lookup
  121. Sundaraneedi M, Eichenberger RM, Al-Hallaf R, Yang D, Sotillo J, Rajan S, Wangchuk P, Giacomin PR, Keene FR, Loukas A, Collins JG, Pearson MS. Polypyridylruthenium(II) complexes exert in vitro and in vivo nematocidal activity and show significant inhibition of parasite acetylcholinesterases.. Int J Parasitol Drugs Drug Resist 2018 Apr;8(1):1-7.
    doi: 10.1016/j.ijpddr.2017.11.005pubmed: 29207309google scholar: lookup
  122. Jamous RM, Ali-Shtayeh MS, Abu-Zaitoun SY, Markovics A, Azaizeh H. Effects of selected Palestinian plants on the in vitro exsheathment of the third stage larvae of gastrointestinal nematodes.. BMC Vet Res 2017 Nov 3;13(1):308.
    doi: 10.1186/s12917-017-1237-7pubmed: 29100544google scholar: lookup
  123. Martis MM, Tarbiat B, Tydén E, Jansson DS, Höglund J. RNA-Seq de novo assembly and differential transcriptome analysis of the nematode Ascaridia galli in relation to in vivo exposure to flubendazole.. PLoS One 2017;12(11):e0185182.
    doi: 10.1371/journal.pone.0185182pubmed: 29099835google scholar: lookup
  124. Pyziel AM, Björck S, Wiklund R, Skarin M, Demiaszkiewicz AW, Höglund J. Gastrointestinal parasites of captive European bison Bison bonasus (L.) with a sign of reduced efficacy of Haemonchus contortus to fenbendazole.. Parasitol Res 2018 Jan;117(1):295-302.
    doi: 10.1007/s00436-017-5663-zpubmed: 29090320google scholar: lookup
  125. Atif M, Estrada-Mondragon A, Nguyen B, Lynch JW, Keramidas A. Effects of glutamate and ivermectin on single glutamate-gated chloride channels of the parasitic nematode H. contortus.. PLoS Pathog 2017 Oct;13(10):e1006663.
    doi: 10.1371/journal.ppat.1006663pubmed: 28968469google scholar: lookup
  126. Onzima RB, Mukiibi R, Ampaire A, Benda KK, Kanis E. Between-breed variations in resistance/resilience to gastrointestinal nematodes among indigenous goat breeds in Uganda.. Trop Anim Health Prod 2017 Dec;49(8):1763-1769.
    doi: 10.1007/s11250-017-1390-9pubmed: 28905295google scholar: lookup
  127. Wang C, Li F, Zhang Z, Yang X, Ahmad AA, Li X, Du A, Hu M. Recent Research Progress in China on Haemonchus contortus.. Front Microbiol 2017;8:1509.
    doi: 10.3389/fmicb.2017.01509pubmed: 28883809google scholar: lookup
  128. Winton VJ, Justen AM, Deng H, Kiessling LL. Deleterious Consequences of UDP-Galactopyranose Mutase Inhibition for Nematodes.. ACS Chem Biol 2017 Sep 15;12(9):2354-2361.
    doi: 10.1021/acschembio.7b00487pubmed: 28732158google scholar: lookup
  129. Romero JJ, Zarate MA, Ogunade IM, Arriola KG, Adesogan AT. Tropical plant supplementation effects on the performance and parasite burden of goats.. Asian-Australas J Anim Sci 2018 Feb;31(2):208-217.
    doi: 10.5713/ajas.17.0321pubmed: 28728358google scholar: lookup
  130. Lažetić V, Fay DS. Molting in C. elegans.. Worm 2017;6(1):e1330246.
    doi: 10.1080/21624054.2017.1330246pubmed: 28702275google scholar: lookup
  131. Krücken J, Fraundorfer K, Mugisha JC, Ramünke S, Sifft KC, Geus D, Habarugira F, Ndoli J, Sendegeya A, Mukampunga C, Bayingana C, Aebischer T, Demeler J, Gahutu JB, Mockenhaupt FP, von Samson-Himmelstjerna G. Reduced efficacy of albendazole against Ascaris lumbricoides in Rwandan schoolchildren.. Int J Parasitol Drugs Drug Resist 2017 Dec;7(3):262-271.
    doi: 10.1016/j.ijpddr.2017.06.001pubmed: 28697451google scholar: lookup
  132. Choi YJ, Bisset SA, Doyle SR, Hallsworth-Pepin K, Martin J, Grant WN, Mitreva M. Genomic introgression mapping of field-derived multiple-anthelmintic resistance in Teladorsagia circumcincta.. PLoS Genet 2017 Jun;13(6):e1006857.
    doi: 10.1371/journal.pgen.1006857pubmed: 28644839google scholar: lookup
  133. Seyoum Z, Demessie Y, Bogale B, Melaku A. Field evaluation of the efficacy of common anthelmintics used in the control of gastrointestinal nematodes of sheep in Dabat district, Northwest Ethiopia.. Ir Vet J 2017;70:18.
    doi: 10.1186/s13620-017-0097-6pubmed: 28596826google scholar: lookup
  134. Mohanraj K, Subhadra S, Kalyanasundaram A, Ilangopathy M, Raman M. Genotyping of benzimidazole resistant and susceptible isolates of Haemonchus contortus from sheep by allele specific PCR.. J Parasit Dis 2017 Mar;41(1):282-288.
    doi: 10.1007/s12639-016-0793-2pubmed: 28316426google scholar: lookup
  135. Seyoum Z, Zewdu A, Dagnachew S, Bogale B. Anthelmintic Resistance of Strongyle Nematodes to Ivermectin and Fenbendazole on Cart Horses in Gondar, Northwest Ethiopia.. Biomed Res Int 2017;2017:5163968.
    doi: 10.1155/2017/5163968pubmed: 28265572google scholar: lookup
  136. Love JW, Kelly LA, Lester HE, Nanjiani I, Taylor MA, Robertson C. Investigating anthelmintic efficacy against gastrointestinal nematodes in cattle by considering appropriate probability distributions for faecal egg count data.. Int J Parasitol Drugs Drug Resist 2017 Apr;7(1):71-82.
    doi: 10.1016/j.ijpddr.2017.01.002pubmed: 28161555google scholar: lookup
  137. Rashwan N, Scott M, Prichard R. Rapid Genotyping of β-tubulin Polymorphisms in Trichuris trichiura and Ascaris lumbricoides.. PLoS Negl Trop Dis 2017 Jan;11(1):e0005205.
    doi: 10.1371/journal.pntd.0005205pubmed: 28081124google scholar: lookup
  138. Kaspar A, Pfister K, Nielsen MK, Silaghi C, Fink H, Scheuerle MC. Detection of Strongylus vulgaris in equine faecal samples by real-time PCR and larval culture - method comparison and occurrence assessment.. BMC Vet Res 2017 Jan 11;13(1):19.
    doi: 10.1186/s12917-016-0918-ypubmed: 28077153google scholar: lookup
  139. Rashwan N, Bourguinat C, Keller K, Gunawardena NK, de Silva N, Prichard R. Isothermal Diagnostic Assays for Monitoring Single Nucleotide Polymorphisms in Necator americanus Associated with Benzimidazole Drug Resistance.. PLoS Negl Trop Dis 2016 Dec;10(12):e0005113.
    doi: 10.1371/journal.pntd.0005113pubmed: 27930648google scholar: lookup
  140. Berk Z, Laurenson YCSM, Forbes AB, Kyriazakis I. Modelling the consequences of targeted selective treatment strategies on performance and emergence of anthelmintic resistance amongst grazing calves.. Int J Parasitol Drugs Drug Resist 2016 Dec;6(3):258-271.
    doi: 10.1016/j.ijpddr.2016.11.002pubmed: 27915061google scholar: lookup
  141. Aggarwal R, Kaur K, Suri M, Bagai U. Anthelmintic potential of Calotropis procera, Azadirachta indica and Punica granatum against Gastrothylax indicus.. J Parasit Dis 2016 Dec;40(4):1230-1238.
    doi: 10.1007/s12639-015-0658-0pubmed: 27876922google scholar: lookup
  142. Ramünke S, Melville L, Rinaldi L, Hertzberg H, de Waal T, von Samson-Himmelstjerna G, Cringoli G, Mavrot F, Skuce P, Krücken J, Demeler J. Benzimidazole resistance survey for Haemonchus, Teladorsagia and Trichostrongylus in three European countries using pyrosequencing including the development of new assays for Trichostrongylus.. Int J Parasitol Drugs Drug Resist 2016 Dec;6(3):230-240.
    doi: 10.1016/j.ijpddr.2016.10.002pubmed: 27821282google scholar: lookup
  143. Zhang Z, Gasser RB, Yang X, Yin F, Zhao G, Bao M, Pan B, Huang W, Wang C, Zou F, Zhou Y, Zhao J, Fang R, Hu M. Two benzimidazole resistance-associated SNPs in the isotype-1 β-tubulin gene predominate in Haemonchus contortus populations from eight regions in China.. Int J Parasitol Drugs Drug Resist 2016 Dec;6(3):199-206.
    doi: 10.1016/j.ijpddr.2016.10.001pubmed: 27760394google scholar: lookup
  144. Weeks JC, Roberts WM, Robinson KJ, Keaney M, Vermeire JJ, Urban JF Jr, Lockery SR, Hawdon JM. Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research.. Int J Parasitol Drugs Drug Resist 2016 Dec;6(3):314-328.
    doi: 10.1016/j.ijpddr.2016.08.001pubmed: 27751868google scholar: lookup
  145. David MA, Orlowski S, Prichard RK, Hashem S, André F, Lespine A. In silico analysis of the binding of anthelmintics to Caenorhabditis elegansP-glycoprotein 1.. Int J Parasitol Drugs Drug Resist 2016 Dec;6(3):299-313.
    doi: 10.1016/j.ijpddr.2016.09.001pubmed: 27746191google scholar: lookup
  146. Beknazarova M, Whiley H, Ross K. Advocating for both Environmental and Clinical Approaches to Control Human Strongyloidiasis.. Pathogens 2016 Sep 30;5(4).
    doi: 10.3390/pathogens5040059pubmed: 27706031google scholar: lookup
  147. Grzybek M, Kukula-Koch W, Strachecka A, Jaworska A, Phiri AM, Paleolog J, Tomczuk K. Evaluation of Anthelmintic Activity and Composition of Pumpkin (Cucurbita pepo L.) Seed Extracts-In Vitro and in Vivo Studies.. Int J Mol Sci 2016 Sep 1;17(9).
    doi: 10.3390/ijms17091456pubmed: 27598135google scholar: lookup
  148. Boval M, Angeon V, Rudel T. Tropical grasslands: A pivotal place for a more multi-functional agriculture.. Ambio 2017 Feb;46(1):48-56.
    doi: 10.1007/s13280-016-0806-5pubmed: 27405654google scholar: lookup
  149. Novobilský A, Amaya Solis N, Skarin M, Höglund J. Assessment of flukicide efficacy against Fasciola hepatica in sheep in Sweden in the absence of a standardised test.. Int J Parasitol Drugs Drug Resist 2016 Dec;6(3):141-147.
    doi: 10.1016/j.ijpddr.2016.06.004pubmed: 27380550google scholar: lookup
  150. Zvinorova PI, Halimani TE, Muchadeyi FC, Matika O, Riggio V, Dzama K. Breeding for resistance to gastrointestinal nematodes - the potential in low-input/output small ruminant production systems.. Vet Parasitol 2016 Jul 30;225:19-28.
    doi: 10.1016/j.vetpar.2016.05.015pubmed: 27369571google scholar: lookup
  151. Chaudhry U, Redman EM, Ashraf K, Shabbir MZ, Rashid MI, Ashraf S, Gilleard JS. Microsatellite marker analysis of Haemonchus contortus populations from Pakistan suggests that frequent benzimidazole drug treatment does not result in a reduction of overall genetic diversity.. Parasit Vectors 2016 Jun 17;9(1):349.
    doi: 10.1186/s13071-016-1624-0pubmed: 27316714google scholar: lookup
  152. Preston S, Luo J, Zhang Y, Jabbar A, Crawford S, Baell J, Hofmann A, Hu M, Zhou HB, Gasser RB. Selenophene and thiophene-core estrogen receptor ligands that inhibit motility and development of parasitic stages of Haemonchus contortus.. Parasit Vectors 2016 Jun 16;9(1):346.
    doi: 10.1186/s13071-016-1612-4pubmed: 27306029google scholar: lookup
  153. Zamanian M, Andersen EC. Prospects and challenges of CRISPR/Cas genome editing for the study and control of neglected vector-borne nematode diseases.. FEBS J 2016 Sep;283(17):3204-21.
    doi: 10.1111/febs.13781pubmed: 27300487google scholar: lookup
  154. Reynolds A, Lindström J, Johnson PC, Mable BK. Evolution of drug-tolerant nematode populations in response to density reduction.. Evol Appl 2016 Jun;9(5):726-38.
    doi: 10.1111/eva.12376pubmed: 27247622google scholar: lookup
  155. Ménez C, Alberich M, Kansoh D, Blanchard A, Lespine A. Acquired Tolerance to Ivermectin and Moxidectin after Drug Selection Pressure in the Nematode Caenorhabditis elegans.. Antimicrob Agents Chemother 2016 Aug;60(8):4809-19.
    doi: 10.1128/AAC.00713-16pubmed: 27246778google scholar: lookup
  156. Beknazarova M, Whiley H, Ross K. Strongyloidiasis: A Disease of Socioeconomic Disadvantage.. Int J Environ Res Public Health 2016 May 20;13(5).
    doi: 10.3390/ijerph13050517pubmed: 27213420google scholar: lookup
  157. Raza A, Kopp SR, Bagnall NH, Jabbar A, Kotze AC. Effects of in vitro exposure to ivermectin and levamisole on the expression patterns of ABC transporters in Haemonchus contortus larvae.. Int J Parasitol Drugs Drug Resist 2016 Aug;6(2):103-15.
    doi: 10.1016/j.ijpddr.2016.03.001pubmed: 27164439google scholar: lookup
  158. Melville LA, McBean D, Fyfe A, Campbell SJ, Palarea-Albaladejo J, Kenyon F. Effect of anthelmintic treatment strategy on strongylid nematode species composition in grazing lambs in Scotland.. Parasit Vectors 2016 Apr 11;9:199.
    doi: 10.1186/s13071-016-1493-6pubmed: 27067011google scholar: lookup
  159. Witola WH, Matthews K, McHugh M. In vitro anthelmintic efficacy of inhibitors of phosphoethanolamine Methyltransferases in Haemonchus contortus.. Int J Parasitol Drugs Drug Resist 2016 Apr;6(1):44-53.
    doi: 10.1016/j.ijpddr.2016.01.002pubmed: 27054063google scholar: lookup
  160. Kumarasingha R, Preston S, Yeo TC, Lim DS, Tu CL, Palombo EA, Shaw JM, Gasser RB, Boag PR. Anthelmintic activity of selected ethno-medicinal plant extracts on parasitic stages of Haemonchus contortus.. Parasit Vectors 2016 Apr 1;9:187.
    doi: 10.1186/s13071-016-1458-9pubmed: 27036205google scholar: lookup
  161. Puspitasari S, Farajallah A, Sulistiawati E, Muladno. Effectiveness of Ivermectin and Albendazole against Haemonchus contortus in Sheep in West Java, Indonesia.. Trop Life Sci Res 2016 Feb;27(1):135-44.
    pubmed: 27019686
  162. Gamboa GV, Palma SD, Lifschitz A, Ballent M, Lanusse C, Passirani C, Benoit JP, Allemandi DA. Ivermectin-loaded lipid nanocapsules: toward the development of a new antiparasitic delivery system for veterinary applications.. Parasitol Res 2016 May;115(5):1945-53.
    doi: 10.1007/s00436-016-4937-1pubmed: 26852126google scholar: lookup
  163. Courtot E, Charvet CL, Beech RN, Harmache A, Wolstenholme AJ, Holden-Dye L, O'Connor V, Peineau N, Woods DJ, Neveu C. Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes.. PLoS Pathog 2015 Dec;11(12):e1005267.
    doi: 10.1371/journal.ppat.1005267pubmed: 26625142google scholar: lookup
  164. Pickering NK, Auvray B, Dodds KG, McEwan JC. Genomic prediction and genome-wide association study for dagginess and host internal parasite resistance in New Zealand sheep.. BMC Genomics 2015 Nov 17;16:958.
    doi: 10.1186/s12864-015-2148-2pubmed: 26576677google scholar: lookup
  165. Mavrot F, Hertzberg H, Torgerson P. Effect of gastro-intestinal nematode infection on sheep performance: a systematic review and meta-analysis.. Parasit Vectors 2015 Oct 24;8:557.
    doi: 10.1186/s13071-015-1164-zpubmed: 26496893google scholar: lookup
  166. Wever CM, Farrington D, Dent JA. The Validation of Nematode-Specific Acetylcholine-Gated Chloride Channels as Potential Anthelmintic Drug Targets.. PLoS One 2015;10(9):e0138804.
    doi: 10.1371/journal.pone.0138804pubmed: 26393923google scholar: lookup
  167. Li BW, Rush AC, Weil GJ. Expression of five acetylcholine receptor subunit genes in Brugia malayi adult worms.. Int J Parasitol Drugs Drug Resist 2015 Dec;5(3):100-9.
    doi: 10.1016/j.ijpddr.2015.04.003pubmed: 26199859google scholar: lookup
  168. McCoy CJ, Warnock ND, Atkinson LE, Atcheson E, Martin RJ, Robertson AP, Maule AG, Marks NJ, Mousley A. RNA interference in adult Ascaris suum--an opportunity for the development of a functional genomics platform that supports organism-, tissue- and cell-based biology in a nematode parasite.. Int J Parasitol 2015 Sep;45(11):673-8.
    doi: 10.1016/j.ijpara.2015.05.003pubmed: 26149642google scholar: lookup
  169. Debrah AY, Specht S, Klarmann-Schulz U, Batsa L, Mand S, Marfo-Debrekyei Y, Fimmers R, Dubben B, Kwarteng A, Osei-Atweneboana M, Boakye D, Ricchiuto A, Büttner M, Adjei O, Mackenzie CD, Hoerauf A. Doxycycline Leads to Sterility and Enhanced Killing of Female Onchocerca volvulus Worms in an Area With Persistent Microfilaridermia After Repeated Ivermectin Treatment: A Randomized, Placebo-Controlled, Double-Blind Trial.. Clin Infect Dis 2015 Aug 15;61(4):517-26.
    doi: 10.1093/cid/civ363pubmed: 25948064google scholar: lookup
  170. Leathwick DM, Ganesh S, Waghorn TS. Evidence for reversion towards anthelmintic susceptibility in Teladorsagia circumcincta in response to resistance management programmes.. Int J Parasitol Drugs Drug Resist 2015 Apr;5(1):9-15.
    doi: 10.1016/j.ijpddr.2015.01.001pubmed: 25941625google scholar: lookup
  171. Law W, Wuescher LM, Ortega A, Hapiak VM, Komuniecki PR, Komuniecki R. Heterologous Expression in Remodeled C. elegans: A Platform for Monoaminergic Agonist Identification and Anthelmintic Screening.. PLoS Pathog 2015 Apr;11(4):e1004794.
    doi: 10.1371/journal.ppat.1004794pubmed: 25928899google scholar: lookup
  172. Zarrin M, Rahdar M, Gholamian A. Biological Control of the Nematode Infective larvae of Trichostrongylidae Family With Filamentous Fungi.. Jundishapur J Microbiol 2015 Mar;8(3):e17614.
    doi: 10.5812/jjm.17614pubmed: 25893084google scholar: lookup
  173. Benavides MV, Sonstegard TS, Kemp S, Mugambi JM, Gibson JP, Baker RL, Hanotte O, Marshall K, Van Tassell C. Identification of novel loci associated with gastrointestinal parasite resistance in a Red Maasai x Dorper backcross population.. PLoS One 2015;10(4):e0122797.
    doi: 10.1371/journal.pone.0122797pubmed: 25867089google scholar: lookup
  174. Schwarz EM, Hu Y, Antoshechkin I, Miller MM, Sternberg PW, Aroian RV. The genome and transcriptome of the zoonotic hookworm Ancylostoma ceylanicum identify infection-specific gene families.. Nat Genet 2015 Apr;47(4):416-22.
    doi: 10.1038/ng.3237pubmed: 25730766google scholar: lookup
  175. Codd EE, Ng HH, McFarlane C, Riccio ES, Doppalapudi R, Mirsalis JC, Horton RJ, Gonzalez AE, Garcia HH, Gilman RH. Preclinical studies on the pharmacokinetics, safety, and toxicology of oxfendazole: toward first in human studies.. Int J Toxicol 2015 Mar-Apr;34(2):129-37.
    doi: 10.1177/1091581815569582pubmed: 25701764google scholar: lookup
  176. Kumar R, Ranjan S, Vishnu PG, Negi M, Senapati PK, Charita VG. Variability of resistance in Black Bengal goats naturally infected with Haemonchus contortus.. J Parasit Dis 2015 Mar;39(1):76-9.
    doi: 10.1007/s12639-013-0282-9pubmed: 25698865google scholar: lookup
  177. Sutherland BJ, Poley JD, Igboeli OO, Jantzen JR, Fast MD, Koop BF, Jones SR. Transcriptomic responses to emamectin benzoate in Pacific and Atlantic Canada salmon lice Lepeophtheirus salmonis with differing levels of drug resistance.. Evol Appl 2015 Feb;8(2):133-48.
    doi: 10.1111/eva.12237pubmed: 25685190google scholar: lookup
  178. Falzon LC, van Leeuwen J, Menzies PI, Jones-Bitton A, Sears W, Jansen JT, Peregrine AS. Comparison of calculation methods used for the determination of anthelmintic resistance in sheep in a temperate continental climate.. Parasitol Res 2015 Apr;114(4):1631-43.
    doi: 10.1007/s00436-014-4253-6pubmed: 25681141google scholar: lookup
  179. Laing R, Bartley DJ, Morrison AA, Rezansoff A, Martinelli A, Laing ST, Gilleard JS. The cytochrome P450 family in the parasitic nematode Haemonchus contortus.. Int J Parasitol 2015 Mar;45(4):243-51.
    doi: 10.1016/j.ijpara.2014.12.001pubmed: 25558056google scholar: lookup
  180. Matthews JB. Anthelmintic resistance in equine nematodes.. Int J Parasitol Drugs Drug Resist 2014 Dec;4(3):310-5.
    doi: 10.1016/j.ijpddr.2014.10.003pubmed: 25516842google scholar: lookup
  181. Buckingham SD, Partridge FA, Sattelle DB. Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: Applications in the search for new anthelmintics.. Int J Parasitol Drugs Drug Resist 2014 Dec;4(3):226-32.
    doi: 10.1016/j.ijpddr.2014.10.004pubmed: 25516833google scholar: lookup
  182. Kotze AC, Hunt PW, Skuce P, von Samson-Himmelstjerna G, Martin RJ, Sager H, Krücken J, Hodgkinson J, Lespine A, Jex AR, Gilleard JS, Beech RN, Wolstenholme AJ, Demeler J, Robertson AP, Charvet CL, Neveu C, Kaminsky R, Rufener L, Alberich M, Menez C, Prichard RK. Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions.. Int J Parasitol Drugs Drug Resist 2014 Dec;4(3):164-84.
    doi: 10.1016/j.ijpddr.2014.07.007pubmed: 25516826google scholar: lookup
  183. Luck AN, Evans CC, Riggs MD, Foster JM, Moorhead AR, Slatko BE, Michalski ML. Concurrent transcriptional profiling of Dirofilaria immitis and its Wolbachia endosymbiont throughout the nematode life cycle reveals coordinated gene expression.. BMC Genomics 2014 Nov 29;15(1):1041.
    doi: 10.1186/1471-2164-15-1041pubmed: 25433394google scholar: lookup
  184. Schneider S, Pfister K, Becher AM, Scheuerle MC. Strongyle infections and parasitic control strategies in German horses - a risk assessment.. BMC Vet Res 2014 Nov 12;10:262.
    doi: 10.1186/s12917-014-0262-zpubmed: 25387542google scholar: lookup
  185. McManus C, do Prado Paim T, de Melo CB, Brasil BS, Paiva SR. Selection methods for resistance to and tolerance of helminths in livestock.. Parasite 2014;21:56.
    doi: 10.1051/parasite/2014055pubmed: 25350972google scholar: lookup
  186. Ballestriero F, Daim M, Penesyan A, Nappi J, Schleheck D, Bazzicalupo P, Di Schiavi E, Egan S. Antinematode activity of Violacein and the role of the insulin/IGF-1 pathway in controlling violacein sensitivity in Caenorhabditis elegans.. PLoS One 2014;9(10):e109201.
    doi: 10.1371/journal.pone.0109201pubmed: 25295516google scholar: lookup
  187. Kotze AC, Ruffell AP, Ingham AB. Phenobarbital induction and chemical synergism demonstrate the role of UDP-glucuronosyltransferases in detoxification of naphthalophos by Haemonchus contortus larvae.. Antimicrob Agents Chemother 2014 Dec;58(12):7475-83.
    doi: 10.1128/AAC.03333-14pubmed: 25288079google scholar: lookup
  188. Dolinská M, Ivanišinová O, Königová A, Várady M. Anthelmintic resistance in sheep gastrointestinal nematodes in Slovakia detected by in-vitro methods.. BMC Vet Res 2014 Oct 1;10:233.
    doi: 10.1186/s12917-014-0233-4pubmed: 25270360google scholar: lookup
  189. Tydén E, Dahlberg J, Karlberg O, Höglund J. Deep amplicon sequencing of preselected isolates of Parascaris equorum in β-tubulin codons associated with benzimidazole resistance in other nematodes.. Parasit Vectors 2014 Aug 29;7:410.
    doi: 10.1186/1756-3305-7-410pubmed: 25175357google scholar: lookup
  190. Keane OM, Keegan JD, Good B, de Waal T, Fanning J, Gottstein M, Casey M, Hurley C, Sheehan M. High level of treatment failure with commonly used anthelmintics on Irish sheep farms.. Ir Vet J 2014;67(1):16.
    doi: 10.1186/2046-0481-67-16pubmed: 25140223google scholar: lookup
  191. Holm SA, Sörensen CR, Thamsborg SM, Enemark HL. Gastrointestinal nematodes and anthelmintic resistance in Danish goat herds.. Parasite 2014;21:37.
    doi: 10.1051/parasite/2014038pubmed: 25076056google scholar: lookup
  192. Martin RJ, Puttachary S, Buxton SK, Verma S, Robertson AP. The Conqueror Worm: recent advances with cholinergic anthelmintics and techniques excite research for better therapeutic drugs.. J Helminthol 2015 Jul;89(4):387-97.
    doi: 10.1017/S0022149X1400039Xpubmed: 24871674google scholar: lookup
  193. Falzon LC, van Leeuwen J, Menzies PI, Jones-Bitton A, Sears W, Jansen JT, Peregrine AS. Comparison of calculation methods used for the determination of anthelmintic resistance in sheep in a temperate continental climate.. Parasitol Res 2014 Jun;113(6):2311-22.
    doi: 10.1007/s00436-014-3886-9pubmed: 24728559google scholar: lookup
  194. Li F, Lok JB, Gasser RB, Korhonen PK, Sandeman MR, Shi D, Zhou R, Li X, Zhou Y, Zhao J, Hu M. Hc-daf-2 encodes an insulin-like receptor kinase in the barber's pole worm, Haemonchus contortus, and restores partial dauer regulation.. Int J Parasitol 2014 Jun;44(7):485-96.
    doi: 10.1016/j.ijpara.2014.03.005pubmed: 24727120google scholar: lookup
  195. Lee SG, Jez JM. Nematode phospholipid metabolism: an example of closing the genome-structure-function circle.. Trends Parasitol 2014 May;30(5):241-50.
    doi: 10.1016/j.pt.2014.03.001pubmed: 24685202google scholar: lookup
  196. Bengtsson B, Greko C. Antibiotic resistance--consequences for animal health, welfare, and food production.. Ups J Med Sci 2014 May;119(2):96-102.
    doi: 10.3109/03009734.2014.901445pubmed: 24678738google scholar: lookup
  197. Demeler J, Gill JH, von Samson-Himmelstjerna G, Sangster NC. The in vitro assay profile of macrocyclic lactone resistance in three species of sheep trichostrongyloids.. Int J Parasitol Drugs Drug Resist 2013 Dec;3:109-18.
    doi: 10.1016/j.ijpddr.2013.04.002pubmed: 24533300google scholar: lookup
  198. Evans CC, Moorhead AR, Storey BE, Wolstenholme AJ, Kaplan RM. Development of an in vitro bioassay for measuring susceptibility to macrocyclic lactone anthelmintics in Dirofilaria immitis.. Int J Parasitol Drugs Drug Resist 2013 Dec;3:102-8.
    doi: 10.1016/j.ijpddr.2013.05.001pubmed: 24533299google scholar: lookup
  199. Kenyon F, McBean D, Greer AW, Burgess CG, Morrison AA, Bartley DJ, Bartley Y, Devin L, Nath M, Jackson F. A comparative study of the effects of four treatment regimes on ivermectin efficacy, body weight and pasture contamination in lambs naturally infected with gastrointestinal nematodes in Scotland.. Int J Parasitol Drugs Drug Resist 2013 Dec;3:77-84.
    doi: 10.1016/j.ijpddr.2013.02.001pubmed: 24533296google scholar: lookup
  200. Sarai RS, Kopp SR, Coleman GT, Kotze AC. Acetylcholine receptor subunit and P-glycoprotein transcription patterns in levamisole-susceptible and -resistant Haemonchus contortus.. Int J Parasitol Drugs Drug Resist 2013 Dec;3:51-8.
    doi: 10.1016/j.ijpddr.2013.01.002pubmed: 24533293google scholar: lookup
  201. Lloberas M, Alvarez L, Entrocasso C, Virkel G, Ballent M, Mate L, Lanusse C, Lifschitz A. Comparative tissue pharmacokinetics and efficacy of moxidectin, abamectin and ivermectin in lambs infected with resistant nematodes: Impact of drug treatments on parasite P-glycoprotein expression.. Int J Parasitol Drugs Drug Resist 2013 Dec;3:20-7.
    doi: 10.1016/j.ijpddr.2012.11.001pubmed: 24533290google scholar: lookup
  202. Prichard R, Ménez C, Lespine A. Moxidectin and the avermectins: Consanguinity but not identity.. Int J Parasitol Drugs Drug Resist 2012 Dec;2:134-53.
    doi: 10.1016/j.ijpddr.2012.04.001pubmed: 24533275google scholar: lookup
  203. Kotze AC, Cowling K, Bagnall NH, Hines BM, Ruffell AP, Hunt PW, Coleman GT. Relative level of thiabendazole resistance associated with the E198A and F200Y SNPs in larvae of a multi-drug resistant isolate of Haemonchus contortus.. Int J Parasitol Drugs Drug Resist 2012 Dec;2:92-7.
    doi: 10.1016/j.ijpddr.2012.02.003pubmed: 24533269google scholar: lookup
  204. McVeigh P, Atkinson L, Marks NJ, Mousley A, Dalzell JJ, Sluder A, Hammerland L, Maule AG. Parasite neuropeptide biology: Seeding rational drug target selection?. Int J Parasitol Drugs Drug Resist 2012 Dec;2:76-91.
    doi: 10.1016/j.ijpddr.2011.10.004pubmed: 24533265google scholar: lookup
  205. Lespine A, Ménez C, Bourguinat C, Prichard RK. P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance.. Int J Parasitol Drugs Drug Resist 2012 Dec;2:58-75.
    doi: 10.1016/j.ijpddr.2011.10.001pubmed: 24533264google scholar: lookup
  206. Wolstenholme AJ. Ion channels and receptor as targets for the control of parasitic nematodes.. Int J Parasitol Drugs Drug Resist 2011 Dec;1(1):2-13.
    doi: 10.1016/j.ijpddr.2011.09.003pubmed: 24533259google scholar: lookup
  207. Romine NM, Martin RJ, Beetham JK. Transcriptomic evaluation of the nicotinic acetylcholine receptor pathway in levamisole-resistant and -sensitive Oesophagostomum dentatum.. Mol Biochem Parasitol 2014 Jan;193(1):66-70.
    doi: 10.1016/j.molbiopara.2014.02.002pubmed: 24530453google scholar: lookup
  208. Assenza F, Elsen JM, Legarra A, Carré C, Sallé G, Robert-Granié C, Moreno CR. Genetic parameters for growth and faecal worm egg count following Haemonchus contortus experimental infestations using pedigree and molecular information.. Genet Sel Evol 2014 Feb 14;46(1):13.
    doi: 10.1186/1297-9686-46-13pubmed: 24528625google scholar: lookup
  209. Treger RS, Otchere J, Keil MF, Quagraine JE, Rai G, Mott BT, Humphries DL, Wilson M, Cappello M, Vermeire JJ. In vitro screening of compounds against laboratory and field isolates of human hookworm reveals quantitative differences in anthelmintic susceptibility.. Am J Trop Med Hyg 2014 Jan;90(1):71-4.
    doi: 10.4269/ajtmh.12-0547pubmed: 24297811google scholar: lookup
  210. Roberts B, Antonopoulos A, Haslam SM, Dicker AJ, McNeilly TN, Johnston SL, Dell A, Knox DP, Britton C. Novel expression of Haemonchus contortus vaccine candidate aminopeptidase H11 using the free-living nematode Caenorhabditis elegans.. Vet Res 2013 Dec 1;44(1):111.
    doi: 10.1186/1297-9716-44-111pubmed: 24289031google scholar: lookup
  211. Laing R, Kikuchi T, Martinelli A, Tsai IJ, Beech RN, Redman E, Holroyd N, Bartley DJ, Beasley H, Britton C, Curran D, Devaney E, Gilabert A, Hunt M, Jackson F, Johnston SL, Kryukov I, Li K, Morrison AA, Reid AJ, Sargison N, Saunders GI, Wasmuth JD, Wolstenholme A, Berriman M, Gilleard JS, Cotton JA. The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery.. Genome Biol 2013 Aug 28;14(8):R88.
    doi: 10.1186/gb-2013-14-8-r88pubmed: 23985316google scholar: lookup
  212. Demeler J, Krüger N, Krücken J, von der Heyden VC, Ramünke S, Küttler U, Miltsch S, López Cepeda M, Knox M, Vercruysse J, Geldhof P, Harder A, von Samson-Himmelstjerna G. Phylogenetic characterization of β-tubulins and development of pyrosequencing assays for benzimidazole resistance in cattle nematodes.. PLoS One 2013;8(8):e70212.
    doi: 10.1371/journal.pone.0070212pubmed: 23950913google scholar: lookup
  213. Roeber F, Jex AR, Gasser RB. Next-generation molecular-diagnostic tools for gastrointestinal nematodes of livestock, with an emphasis on small ruminants: a turning point?. Adv Parasitol 2013;83:267-333.
    doi: 10.1016/B978-0-12-407705-8.00004-5pubmed: 23876874google scholar: lookup
  214. Ondrovics M, Silbermayr K, Mitreva M, Young ND, Razzazi-Fazeli E, Gasser RB, Joachim A. Proteomic analysis of Oesophagostomum dentatum (Nematoda) during larval transition, and the effects of hydrolase inhibitors on development.. PLoS One 2013;8(5):e63955.
    doi: 10.1371/journal.pone.0063955pubmed: 23717515google scholar: lookup
  215. Roeber F, Jex AR, Gasser RB. Impact of gastrointestinal parasitic nematodes of sheep, and the role of advanced molecular tools for exploring epidemiology and drug resistance - an Australian perspective.. Parasit Vectors 2013 May 27;6:153.
    doi: 10.1186/1756-3305-6-153pubmed: 23711194google scholar: lookup
  216. Wesener DA, May JF, Huffman EM, Kiessling LL. UDP-galactopyranose mutase in nematodes.. Biochemistry 2013 Jun 25;52(25):4391-8.
    doi: 10.1021/bi400264dpubmed: 23697711google scholar: lookup
  217. Shalaby HA. Anthelmintics Resistance; How to Overcome it?. Iran J Parasitol 2013 Jan;8(1):18-32.
    pubmed: 23682256
  218. Rizvi A, Khan R, Khan AU, Ghani Z, Ghani S, Saifullah MK, Saleemuddin M, Abidi SM. Observations on in vitro and in vivo antimicrofilarial effects of Bishop's weed (Trachispermum ammi).. J Parasit Dis 2012 Apr;36(1):125-8.
    doi: 10.1007/s12639-011-0075-ypubmed: 23543135google scholar: lookup
  219. Puttachary S, Trailovic SM, Robertson AP, Thompson DP, Woods DJ, Martin RJ. Derquantel and abamectin: effects and interactions on isolated tissues of Ascaris suum.. Mol Biochem Parasitol 2013 Apr;188(2):79-86.
    doi: 10.1016/j.molbiopara.2013.02.004pubmed: 23523993google scholar: lookup
  220. Atkinson LE, Stevenson M, McCoy CJ, Marks NJ, Fleming C, Zamanian M, Day TA, Kimber MJ, Maule AG, Mousley A. flp-32 Ligand/receptor silencing phenocopy faster plant pathogenic nematodes.. PLoS Pathog 2013 Feb;9(2):e1003169.
    doi: 10.1371/journal.ppat.1003169pubmed: 23468621google scholar: lookup
  221. Heizer E, Zarlenga DS, Rosa B, Gao X, Gasser RB, De Graef J, Geldhof P, Mitreva M. Transcriptome analyses reveal protein and domain families that delineate stage-related development in the economically important parasitic nematodes, Ostertagia ostertagi and Cooperia oncophora.. BMC Genomics 2013 Feb 22;14:118.
    doi: 10.1186/1471-2164-14-118pubmed: 23432754google scholar: lookup
  222. Suárez G, Alvarez L, Castells D, Correa O, Fagiolino P, Lanusse C. Relative bioavailability and comparative clinical efficacy of different ivermectin oral formulations in lambs.. BMC Vet Res 2013 Feb 11;9:27.
    doi: 10.1186/1746-6148-9-27pubmed: 23398629google scholar: lookup
  223. Ndjonka D, Rapado LN, Silber AM, Liebau E, Wrenger C. Natural products as a source for treating neglected parasitic diseases.. Int J Mol Sci 2013 Feb 6;14(2):3395-439.
    doi: 10.3390/ijms14023395pubmed: 23389040google scholar: lookup
  224. Roeber F, Jex AR, Gasser RB. Advances in the diagnosis of key gastrointestinal nematode infections of livestock, with an emphasis on small ruminants.. Biotechnol Adv 2013 Dec;31(8):1135-52.
    doi: 10.1016/j.biotechadv.2013.01.008pubmed: 23376340google scholar: lookup
  225. De Graef J, Demeler J, Skuce P, Mitreva M, Von Samson-Himmelstjerna G, Vercruysse J, Claerebout E, Geldhof P. Gene expression analysis of ABC transporters in a resistant Cooperia oncophora isolate following in vivo and in vitro exposure to macrocyclic lactones.. Parasitology 2013 Apr;140(4):499-508.
    doi: 10.1017/S0031182012001849pubmed: 23279803google scholar: lookup
  226. Good B, Hanrahan JP, de Waal DT, Patten T, Kinsella A, Lynch CO. Anthelmintic-resistant nematodes in Irish commercial sheep flocks- the state of play.. Ir Vet J 2012 Dec 22;65(1):21.
    doi: 10.1186/2046-0481-65-21pubmed: 23259836google scholar: lookup
  227. Hu Y, Zhan B, Keegan B, Yiu YY, Miller MM, Jones K, Aroian RV. Mechanistic and single-dose in vivo therapeutic studies of Cry5B anthelmintic action against hookworms.. PLoS Negl Trop Dis 2012;6(11):e1900.
    doi: 10.1371/journal.pntd.0001900pubmed: 23145203google scholar: lookup
  228. Buske R, Santurio JM, de Oliveira CV, Bianchini LA, da Silva JH, de la Rue ML. In vitro influence of temperature on the biological control activity of the fungus Duddingtonia flagrans against Haemonchus contortus in sheep.. Parasitol Res 2013 Feb;112(2):473-8.
    doi: 10.1007/s00436-012-3156-7pubmed: 23052786google scholar: lookup
  229. Al-Rofaai A, Rahman WA, Abdulghani M. Sensitivity of two in vitro assays for evaluating plant activity against the infective stage of Haemonchus contortus strains.. Parasitol Res 2013 Feb;112(2):893-8.
    doi: 10.1007/s00436-012-3113-5pubmed: 22961237google scholar: lookup
  230. Shao H, Li X, Nolan TJ, Massey HC Jr, Pearce EJ, Lok JB. Transposon-mediated chromosomal integration of transgenes in the parasitic nematode Strongyloides ratti and establishment of stable transgenic lines.. PLoS Pathog 2012;8(8):e1002871.
    doi: 10.1371/journal.ppat.1002871pubmed: 22912584google scholar: lookup
  231. Kuzmina TA, Lyons ET, Tolliver SC, Dzeverin II, Kharchenko VA. Fecundity of various species of strongylids (Nematoda: Strongylidae)--parasites of domestic horses.. Parasitol Res 2012 Dec;111(6):2265-71.
    doi: 10.1007/s00436-012-3077-5pubmed: 22903448google scholar: lookup
  232. Idika IK, Okonkwo EA, Onah DN, Ezeh IO, Iheagwam CN, Nwosu CO. Efficacy of levamisole and ivermectin in the control of bovine parasitic gastroenteritis in the sub-humid savanna zone of southeastern Nigeria.. Parasitol Res 2012 Oct;111(4):1683-7.
    doi: 10.1007/s00436-012-3007-6pubmed: 22760239google scholar: lookup
  233. Choe KP, Leung CK, Miyamoto MM. Unique structure and regulation of the nematode detoxification gene regulator, SKN-1: implications to understanding and controlling drug resistance.. Drug Metab Rev 2012 Aug;44(3):209-23.
    doi: 10.3109/03602532.2012.684799pubmed: 22656429google scholar: lookup
  234. Roeber F, Larsen JW, Anderson N, Campbell AJ, Anderson GA, Gasser RB, Jex AR. A molecular diagnostic tool to replace larval culture in conventional faecal egg count reduction testing in sheep.. PLoS One 2012;7(5):e37327.
    doi: 10.1371/journal.pone.0037327pubmed: 22629381google scholar: lookup
  235. Höglund J, Morrison DA, Engström A, Nejsum P, Jansson DS. Population genetic structure of Ascaridia galli re-emerging in non-caged laying hens.. Parasit Vectors 2012 May 20;5:97.
    doi: 10.1186/1756-3305-5-97pubmed: 22607623google scholar: lookup
  236. Charvet CL, Robertson AP, Cabaret J, Martin RJ, Neveu C. Selective effect of the anthelmintic bephenium on Haemonchus contortus levamisole-sensitive acetylcholine receptors.. Invert Neurosci 2012 Jun;12(1):43-51.
    doi: 10.1007/s10158-012-0130-0pubmed: 22526556google scholar: lookup
  237. Millares P, Lacourse EJ, Perally S, Ward DA, Prescott MC, Hodgkinson JE, Brophy PM, Rees HH. Proteomic profiling and protein identification by MALDI-TOF mass spectrometry in unsequenced parasitic nematodes.. PLoS One 2012;7(3):e33590.
    doi: 10.1371/journal.pone.0033590pubmed: 22479418google scholar: lookup
  238. Belew S, Hussien J, Regassa F, Belay K, Tolosa T. Susceptibility assay of Haemonchus contortus to commonly used anthelmintics in Jimma, southwest Ethiopia.. Trop Anim Health Prod 2012 Oct;44(7):1599-603.
    doi: 10.1007/s11250-012-0113-5pubmed: 22402797google scholar: lookup
  239. Redman E, Sargison N, Whitelaw F, Jackson F, Morrison A, Bartley DJ, Gilleard JS. Introgression of ivermectin resistance genes into a susceptible Haemonchus contortus strain by multiple backcrossing.. PLoS Pathog 2012 Feb;8(2):e1002534.
    doi: 10.1371/journal.ppat.1002534pubmed: 22359506google scholar: lookup
  240. Laing ST, Ivens A, Butler V, Ravikumar SP, Laing R, Woods DJ, Gilleard JS. The transcriptional response of Caenorhabditis elegans to Ivermectin exposure identifies novel genes involved in the response to reduced food intake.. PLoS One 2012;7(2):e31367.
    doi: 10.1371/journal.pone.0031367pubmed: 22348077google scholar: lookup
  241. Nabavi R, Shayan P, Shokrani H, Eslami A, Bokaie S. Evaluation of Benzimidazole Resistance in Haemonchus contortus Using Comparative PCR-RFLP Methods.. Iran J Parasitol 2011 Jun;6(2):45-53.
    pubmed: 22347287
  242. Viljoen GJ, Luckins AG. The role of nuclear technologies in the diagnosis and control of livestock diseases--a review.. Trop Anim Health Prod 2012 Oct;44(7):1341-66.
    doi: 10.1007/s11250-012-0077-5pubmed: 22286376google scholar: lookup
  243. Tritten L, Silbereisen A, Keiser J. In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections.. PLoS Negl Trop Dis 2011 Dec;5(12):e1457.
    doi: 10.1371/journal.pntd.0001457pubmed: 22216366google scholar: lookup
  244. Zhi X, Zhou XE, Melcher K, Motola DL, Gelmedin V, Hawdon J, Kliewer SA, Mangelsdorf DJ, Xu HE. Structural conservation of ligand binding reveals a bile acid-like signaling pathway in nematodes.. J Biol Chem 2012 Feb 10;287(7):4894-903.
    doi: 10.1074/jbc.M111.315242pubmed: 22170062google scholar: lookup
  245. Kuzmina TA. Contamination of the environment by strongylid (Nematoda: Strongylidae) infective larvae at horse farms of various types in Ukraine.. Parasitol Res 2012 May;110(5):1665-74.
    doi: 10.1007/s00436-011-2684-xpubmed: 22006190google scholar: lookup
  246. Roy B, Swargiary A, Syiem D, Tandon V. Potentilla fulgens (Family Rosaceae), a medicinal plant of north-east India: a natural anthelmintic?. J Parasit Dis 2010 Oct;34(2):83-8.
    doi: 10.1007/s12639-010-0018-zpubmed: 21966126google scholar: lookup
  247. Glendinning SK, Buckingham SD, Sattelle DB, Wonnacott S, Wolstenholme AJ. Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans.. PLoS One 2011;6(7):e22390.
    doi: 10.1371/journal.pone.0022390pubmed: 21818319google scholar: lookup
  248. Olliaro P, Seiler J, Kuesel A, Horton J, Clark JN, Don R, Keiser J. Potential drug development candidates for human soil-transmitted helminthiases.. PLoS Negl Trop Dis 2011 Jun;5(6):e1138.
    doi: 10.1371/journal.pntd.0001138pubmed: 21695247google scholar: lookup
  249. Carr JA, Parashar A, Gibson R, Robertson AP, Martin RJ, Pandey S. A microfluidic platform for high-sensitivity, real-time drug screening on C. elegans and parasitic nematodes.. Lab Chip 2011 Jul 21;11(14):2385-96.
    doi: 10.1039/c1lc20170kpubmed: 21647497google scholar: lookup
  250. Boulin T, Fauvin A, Charvet CL, Cortet J, Cabaret J, Bessereau JL, Neveu C. Functional reconstitution of Haemonchus contortus acetylcholine receptors in Xenopus oocytes provides mechanistic insights into levamisole resistance.. Br J Pharmacol 2011 Nov;164(5):1421-32.
    doi: 10.1111/j.1476-5381.2011.01420.xpubmed: 21486278google scholar: lookup
  251. Duan LP, Wen AD, Wu NB, Tao Y, Zhang HB. Synthesis and anti-intestinal nematode activity of variously substituted benzonaphthyridine derivatives.. Molecules 2011 Feb 14;16(2):1593-602.
    doi: 10.3390/molecules16021593pubmed: 21321530google scholar: lookup
  252. Crump A, Ōmura S. Ivermectin, 'wonder drug' from Japan: the human use perspective.. Proc Jpn Acad Ser B Phys Biol Sci 2011;87(2):13-28.
    doi: 10.2183/pjab.87.13pubmed: 21321478google scholar: lookup
  253. Crane MA, Khallaayoune K, Scantlebury C, Christley RM. A randomized triple blind trial to assess the effect of an anthelmintic programme for working equids in Morocco.. BMC Vet Res 2011 Jan 5;7:1.
    doi: 10.1186/1746-6148-7-1pubmed: 21208398google scholar: lookup
  254. Becher AM, Pfister K. [The efficacy of anthelmintic drugs against horse strongyles in the area of Salzburg and preliminary results of selective anthelmintic treatment].. Wien Klin Wochenschr 2010 Oct;122 Suppl 3:71-5.
    doi: 10.1007/s00508-010-1441-ypubmed: 20924696google scholar: lookup
  255. Cantacessi C, Mitreva M, Campbell BE, Hall RS, Young ND, Jex AR, Ranganathan S, Gasser RB. First transcriptomic analysis of the economically important parasitic nematode, Trichostrongylus colubriformis, using a next-generation sequencing approach.. Infect Genet Evol 2010 Dec;10(8):1199-207.
    doi: 10.1016/j.meegid.2010.07.024pubmed: 20692378google scholar: lookup
  256. Chen B, Deutmeyer A, Carr J, Robertson AP, Martin RJ, Pandey S. Microfluidic bioassay to characterize parasitic nematode phenotype and anthelmintic resistance.. Parasitology 2011 Jan;138(1):80-8.
    doi: 10.1017/S0031182010001010pubmed: 20663251google scholar: lookup
  257. Devaney E, Winter AD, Britton C. microRNAs: a role in drug resistance in parasitic nematodes?. Trends Parasitol 2010 Sep;26(9):428-33.
    doi: 10.1016/j.pt.2010.05.003pubmed: 20541972google scholar: lookup
  258. Little PR, Hodges A, Watson TG, Seed JA, Maeder SJ. Field efficacy and safety of an oral formulation of the novel combination anthelmintic, derquantel-abamectin, in sheep in New Zealand.. N Z Vet J 2010 Jun;58(3):121-9.
    doi: 10.1080/00480169.2010.67513pubmed: 20514085google scholar: lookup
  259. Mengome LE, Akue JP, Souza A, Feuya Tchoua GR, Nsi Emvo E. In vitro activities of plant extracts on human Loa loa isolates and cytotoxicity for eukaryotic cells.. Parasitol Res 2010 Aug;107(3):643-50.
    doi: 10.1007/s00436-010-1910-2pubmed: 20495930google scholar: lookup
  260. Zhou QJ, Zhang HL, Jiang XL, Du AF. The gene structure and promoter region of the vaccine target aminopeptidase H11 from the blood-sucking nematode parasite of ruminants, Haemonchus contortus.. Funct Integr Genomics 2010 Nov;10(4):589-601.
    doi: 10.1007/s10142-010-0172-5pubmed: 20437190google scholar: lookup
  261. Hu Y, Platzer EG, Bellier A, Aroian RV. Discovery of a highly synergistic anthelmintic combination that shows mutual hypersusceptibility.. Proc Natl Acad Sci U S A 2010 Mar 30;107(13):5955-60.
    doi: 10.1073/pnas.0912327107pubmed: 20231450google scholar: lookup
  262. Paraud C, Pors I, Rehby L, Chartier C. Absence of ivermectin resistance in a survey on dairy goat nematodes in France.. Parasitol Res 2010 May;106(6):1475-9.
    doi: 10.1007/s00436-010-1781-6pubmed: 20155368google scholar: lookup
  263. Huang YH, Colgrave ML, Clark RJ, Kotze AC, Craik DJ. Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activity.. J Biol Chem 2010 Apr 2;285(14):10797-805.
    doi: 10.1074/jbc.M109.089854pubmed: 20103593google scholar: lookup
  264. Puttachary S, Robertson AP, Clark CL, Martin RJ. Levamisole and ryanodine receptors. II: An electrophysiological study in Ascaris suum.. Mol Biochem Parasitol 2010 May;171(1):8-16.
    doi: 10.1016/j.molbiopara.2009.12.006pubmed: 20064567google scholar: lookup
  265. Churcher TS, Pion SD, Osei-Atweneboana MY, Prichard RK, Awadzi K, Boussinesq M, Collins RC, Whitworth JA, Basáñez MG. Identifying sub-optimal responses to ivermectin in the treatment of River Blindness.. Proc Natl Acad Sci U S A 2009 Sep 29;106(39):16716-21.
    doi: 10.1073/pnas.0906176106pubmed: 19805362google scholar: lookup
  266. Reinemeyer CR. Diagnosis and control of anthelmintic-resistant Parascaris equorum.. Parasit Vectors 2009 Sep 25;2 Suppl 2(Suppl 2):S8.
    doi: 10.1186/1756-3305-2-S2-S8pubmed: 19778469google scholar: lookup
  267. Nielsen MK. Restrictions of anthelmintic usage: perspectives and potential consequences.. Parasit Vectors 2009 Sep 25;2 Suppl 2(Suppl 2):S7.
    doi: 10.1186/1756-3305-2-S2-S7pubmed: 19778468google scholar: lookup
  268. von Samson-Himmelstjerna G, Traversa D, Demeler J, Rohn K, Milillo P, Schurmann S, Lia R, Perrucci S, di Regalbono AF, Beraldo P, Barnes H, Cobb R, Boeckh A. Effects of worm control practices examined by a combined faecal egg count and questionnaire survey on horse farms in Germany, Italy and the UK.. Parasit Vectors 2009 Sep 25;2 Suppl 2(Suppl 2):S3.
    doi: 10.1186/1756-3305-2-S2-S3pubmed: 19778464google scholar: lookup
  269. Traversa D, von Samson-Himmelstjerna G, Demeler J, Milillo P, Schürmann S, Barnes H, Otranto D, Perrucci S, di Regalbono AF, Beraldo P, Boeckh A, Cobb R. Anthelmintic resistance in cyathostomin populations from horse yards in Italy, United Kingdom and Germany.. Parasit Vectors 2009 Sep 25;2 Suppl 2(Suppl 2):S2.
    doi: 10.1186/1756-3305-2-S2-S2pubmed: 19778463google scholar: lookup
  270. Hu Y, Xiao SH, Aroian RV. The new anthelmintic tribendimidine is an L-type (levamisole and pyrantel) nicotinic acetylcholine receptor agonist.. PLoS Negl Trop Dis 2009 Aug 11;3(8):e499.
    doi: 10.1371/journal.pntd.0000499pubmed: 19668355google scholar: lookup
  271. Wang Z, Zhou XE, Motola DL, Gao X, Suino-Powell K, Conneely A, Ogata C, Sharma KK, Auchus RJ, Lok JB, Hawdon JM, Kliewer SA, Xu HE, Mangelsdorf DJ. Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.. Proc Natl Acad Sci U S A 2009 Jun 9;106(23):9138-43.
    doi: 10.1073/pnas.0904064106pubmed: 19497877google scholar: lookup
  272. von Samson-Himmelstjerna G, Coles GC, Jackson F, Bauer C, Borgsteede F, Cirak VY, Demeler J, Donnan A, Dorny P, Epe C, Harder A, Höglund J, Kaminsky R, Kerboeuf D, Küttler U, Papadopoulos E, Posedi J, Small J, Várady M, Vercruysse J, Wirtherle N. Standardization of the egg hatch test for the detection of benzimidazole resistance in parasitic nematodes.. Parasitol Res 2009 Sep;105(3):825-34.
    doi: 10.1007/s00436-009-1466-1pubmed: 19452165google scholar: lookup
  273. Rufener L, Mäser P, Roditi I, Kaminsky R. Haemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantel.. PLoS Pathog 2009 Apr;5(4):e1000380.
    doi: 10.1371/journal.ppat.1000380pubmed: 19360096google scholar: lookup
  274. Débarre F, Lenormand T, Gandon S. Evolutionary epidemiology of drug-resistance in space.. PLoS Comput Biol 2009 Apr;5(4):e1000337.
    doi: 10.1371/journal.pcbi.1000337pubmed: 19343211google scholar: lookup
  275. Choe KP, Przybysz AJ, Strange K. The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans.. Mol Cell Biol 2009 May;29(10):2704-15.
    doi: 10.1128/MCB.01811-08pubmed: 19273594google scholar: lookup
  276. Yazwinski TA, Tucker CA, Hornsby JA, Powell JG, Reynolds JL, Johnson ZB, Lindsey W, Silver TK. Effectiveness evaluation of several cattle anthelmintics via the fecal egg count reduction test.. Parasitol Res 2009 Jul;105(1):71-6.
    doi: 10.1007/s00436-009-1364-6pubmed: 19214571google scholar: lookup
  277. Robertson AP, Puttachary S, Buxton SK, Martin RJ. Electrophysiological recording from parasitic nematode muscle.. Invert Neurosci 2008 Dec;8(4):167-75.
    doi: 10.1007/s10158-008-0080-8pubmed: 19005711google scholar: lookup
  278. Kotze AC, Kopp SR. The potential impact of density dependent fecundity on the use of the faecal egg count reduction test for detecting drug resistance in human hookworms.. PLoS Negl Trop Dis 2008 Oct 1;2(10):e297.
    doi: 10.1371/journal.pntd.0000297pubmed: 18827883google scholar: lookup
  279. Alexandre G, Leimbacher F, Maurice O, Domarin D, Naves M, Mandonnet N. Goat farming systems in Martinique: management and breeding strategies.. Trop Anim Health Prod 2009 Apr;41(4):635-44.
    doi: 10.1007/s11250-008-9235-1pubmed: 18815894google scholar: lookup
  280. Behnke JM, Buttle DJ, Stepek G, Lowe A, Duce IR. Developing novel anthelmintics from plant cysteine proteinases.. Parasit Vectors 2008 Sep 1;1(1):29.
    doi: 10.1186/1756-3305-1-29pubmed: 18761736google scholar: lookup
  281. Verma S, Robertson AP, Martin RJ. Effects of SDPNFLRF-amide (PF1) on voltage-activated currents in Ascaris suum muscle.. Int J Parasitol 2009 Feb;39(3):315-26.
    doi: 10.1016/j.ijpara.2008.07.007pubmed: 18760280google scholar: lookup
  282. Lia RP, Traversa D, Iorio R, Otranto D, Klei TR, Ricci V, Giangaspero A. Preliminary molecular identification of drug resistant cyathostomes in Italy.. Vet Res Commun 2008 Sep;32 Suppl 1:S211-3.
    doi: 10.1007/s11259-008-9156-5pubmed: 18685966google scholar: lookup
  283. Kaminsky R, Gauvry N, Schorderet Weber S, Skripsky T, Bouvier J, Wenger A, Schroeder F, Desaules Y, Hotz R, Goebel T, Hosking BC, Pautrat F, Wieland-Berghausen S, Ducray P. Identification of the amino-acetonitrile derivative monepantel (AAD 1566) as a new anthelmintic drug development candidate.. Parasitol Res 2008 Sep;103(4):931-9.
    doi: 10.1007/s00436-008-1080-7pubmed: 18594861google scholar: lookup
  284. Jabbar A, Iqbal Z, Saddiqi HA, Babar W, Saeed M. Prevalence of multiple anthelmintic resistant gastrointestinal nematodes in dairy goats in a desolated tract (Pakistan).. Parasitol Res 2008 Jun;103(1):29-35.
    doi: 10.1007/s00436-008-0923-6pubmed: 18301923google scholar: lookup
  285. Robertson AP, Martin RJ. Ion-channels on parasite muscle: pharmacology and physiology.. Invert Neurosci 2007 Dec;7(4):209-17.
    doi: 10.1007/s10158-007-0059-xpubmed: 17999098google scholar: lookup
  286. Traversa D, Paoletti B, Otranto D, Miller J. First report of multiple drug resistance in trichostrongyles affecting sheep under field conditions in Italy.. Parasitol Res 2007 Nov;101(6):1713-6.
    doi: 10.1007/s00436-007-0707-4pubmed: 17712570google scholar: lookup
  287. Traversa D, Iorio R, Klei TR, Kharchenko VA, Gawor J, Otranto D, Sparagano OA. New method for simultaneous species-specific identification of equine strongyles (nematoda, strongylida) by reverse line blot hybridization.. J Clin Microbiol 2007 Sep;45(9):2937-42.
    doi: 10.1128/JCM.00714-07pubmed: 17626168google scholar: lookup
  288. Köse M, Kozan E, Sevimli FK, Eser M. The resistance of nematode parasites in sheep against anthelmintic drugs widely used in Western Turkey.. Parasitol Res 2007 Aug;101(3):563-7.
    doi: 10.1007/s00436-007-0514-ypubmed: 17372762google scholar: lookup
  289. Harmon AF, Williams ZB, Zarlenga DS, Hildreth MB. Real-time PCR for quantifying Haemonchus contortus eggs and potential limiting factors.. Parasitol Res 2007 Jun;101(1):71-6.
    doi: 10.1007/s00436-006-0428-0pubmed: 17206500google scholar: lookup
  290. Schwenkenbecher JM, Kaplan RM. Development and characterization of microsatellite markers for the canine hookworm, Ancylostoma caninum.. Parasitol Res 2007 Apr;100(5):1015-21.
    doi: 10.1007/s00436-006-0367-9pubmed: 17136387google scholar: lookup
  291. Crawford AM, Paterson KA, Dodds KG, Diez Tascon C, Williamson PA, Roberts Thomson M, Bisset SA, Beattie AE, Greer GJ, Green RS, Wheeler R, Shaw RJ, Knowler K, McEwan JC. Discovery of quantitative trait loci for resistance to parasitic nematode infection in sheep: I. Analysis of outcross pedigrees.. BMC Genomics 2006 Jul 18;7:178.
    doi: 10.1186/1471-2164-7-178pubmed: 16846521google scholar: lookup
  292. Blackhall WJ, Drogemuller M, Schnieder T, von Samson-Himmelstjerna G. Expression of recombinant beta-tubulin alleles from Cylicocyclus nassatus (Cyathostominae).. Parasitol Res 2006 Nov;99(6):687-93.
    doi: 10.1007/s00436-006-0213-0pubmed: 16738892google scholar: lookup
  293. Keane OM, Zadissa A, Wilson T, Hyndman DL, Greer GJ, Baird DB, McCulloch AF, Crawford AM, McEwan JC. Gene expression profiling of naïve sheep genetically resistant and susceptible to gastrointestinal nematodes.. BMC Genomics 2006 Mar 6;7:42.
    doi: 10.1186/1471-2164-7-42pubmed: 16515715google scholar: lookup
  294. Paraud C, Pors I, Chicard C, Chartier C. Comparative efficacy of the nematode-trapping fungus Duddingtonia flagrans against Haemonchus contortus, Teladorsagia circumcincta and Trichostrongylus colubriformis in goat faeces: influence of the duration and of the temperature of coproculture.. Parasitol Res 2006 Feb;98(3):207-13.
    doi: 10.1007/s00436-005-0028-4pubmed: 16328368google scholar: lookup
  295. Tinar R, Akyol CV, Cirak VY, Senlik B, Bauer C. Investigations on the seasonal patterns of strongyle infections in grazing lambs, and the occurrence of anthelmintic resistance on sheep and goat farms in western Anatolia, Turkey.. Parasitol Res 2005 Apr;96(1):18-23.
    doi: 10.1007/s00436-005-1312-zpubmed: 15765247google scholar: lookup
Subscribe to our newsletter
Join 99,344 horse owners like you who receive our email updates on horse health and nutrition.