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Home / Equine Research Bank / J Vet Intern Med / Effect of airway disease on blood gas exchange in racehorses...
Journal of veterinary internal medicine2005; 19(1); 87-92; doi: 10.1892/0891-6640(2005)19<87:eoadob>2.0.co;2

Effect of airway disease on blood gas exchange in racehorses.

Abstract: Inflammatory Airway Disease (IAD), exercise-induced pulmonary hemorrhage (EIPH), and upper airway obstruction (UAO) are common respiratory tract diseases that can decrease performance. The purpose of this retrospective study was to compare bronchoalveolar lavage fluid cytology and arterial blood gas analysis during a treadmill test by poorly performing racehorses presented to Purdue University. One hundred thirty-two horses with a history of poor performance were included in this study. Ten horses with no history or diagnosis of EIPH, IAD, or UAO served as controls. Horses were evaluated by rhinolaryngoscopy for upper airway abnormalities and underwent a standardized treadmill test, and samples were collected for blood gas analysis. Horses with IAD or EIPH had a more severe exercise-induced hypoxemia, (mean+/-SD; 84.8+/-1.5 and 86.0+/-1.7 mm Hg average Pao2, respectively), than horses in the control group (92.8+/-2.1 mm Hg). The average Pao2 of horses with only UAO (88.3+/-3.3 mm Hg) was not significantly different from control horses. Gas exchanges were the most severely impaired in horses affected with both EIPH and UAO because they exhibited the lowest Pao2 and highest Paco2 values (66.5+/-15.2 and 52.2+/-6.3 mm Hg, respectively).
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Publication Date: 2005-02-18 PubMed ID: 15715053DOI: 10.1892/0891-6640(2005)19<87:eoadob>2.0.co;2Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article presents a study on the impact of common respiratory diseases in racehorses on their blood gas exchange and overall performance.

Objective and Methodology:

  • The study aimed at comparing the results of bronchoalveolar lavage fluid cytology and arterial blood gas analysis under a treadmill test on racehorses that were underperforming due to inflammatory airway disease (IAD), exercise-induced pulmonary hemorrhage (EIPH), and upper airway obstruction (UAO).
  • 132 racehorses with a history of poor performance were included in the study, along with the control group of 10 horses without any history or diagnosis of IAD, EIPH, or UAO.
  • The horses were evaluated using rhinolaryngoscopy for potential upper airway abnormalities and were put through a standardized treadmill test while samples were collected for blood gas analysis.

Findings:

  • Horses suffering from IAD or EIPH showed more severe exercise-induced hypoxemia (lower oxygen levels in the blood during exercise) than the control group, with their average Pao2 — a measure of the oxygen level in arterial blood — significantly lower than that in control horses.
  • The average Pao2 of horses with only UAO was not considerably different from that of the control horses.
  • Contrastingly, horses with both EIPH and UAO showed the greatest impairment in gas exchanges. These horses displayed the lowest Pao2 and the highest Paco2 — a measure of the level of carbon dioxide in the blood — values thereby indicating severely impaired lung function and blood oxygenation.

Implication:

  • According to the research, the presence of respiratory diseases such as IAD and EIPH in racehorses can significantly impair their performance by causing exercise-induced hypoxemia or reduced oxygen supply to the muscles during exercise. Understanding these diseases and how they impact the blood gas exchange can help in the diagnosis, treatment, and management of underperforming racehorses.

Cite This Article

APA
Sánchez A, Couëtil LL, Ward MP, Clark SP. (2005). Effect of airway disease on blood gas exchange in racehorses. J Vet Intern Med, 19(1), 87-92. https://doi.org/10.1892/0891-6640(2005)19<87:eoadob>2.0.co;2

Publication

Journal of veterinary internal medicine
ISSN: 0891-6640
NlmUniqueID: 8708660
Country: United States
Language: English
Volume: 19
Issue: 1
Pages: 87-92

Researcher Affiliations

Sánchez, A
  • Department of Veterinary Clinical Sciences, Purdue University School of Veterinary Medicine, West Lafayette, IN 47907-1248, USA.
Couëtil, L L
    Ward, M P
      Clark, S P

        MeSH Terms

        • Animals
        • Blood Gas Analysis / veterinary
        • Bronchoalveolar Lavage Fluid / cytology
        • Exercise Test / veterinary
        • Horse Diseases / blood
        • Horses
        • Hypoxia / etiology
        • Hypoxia / veterinary
        • Lactic Acid / blood
        • Laryngoscopy / veterinary
        • Physical Conditioning, Animal
        • Pulmonary Gas Exchange
        • Respiratory Tract Diseases / blood
        • Respiratory Tract Diseases / veterinary
        • Retrospective Studies
        • Spectrophotometry / veterinary

        Citations

        This article has been cited 18 times.
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