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Home / Equine Research Bank / Bone / Effects of mineral content on the fracture properties of equ...
Bone2012; 50(6); 1275-1280; doi: 10.1016/j.bone.2012.02.018

Effects of mineral content on the fracture properties of equine cortical bone in double-notched beams.

Abstract: We recently developed a method to measure cortical bone fracture initiation toughness using a double-notched beam in four-point bending. This method was used to test the hypothesis that mineralization around the two notch roots is correlated with fracture toughness and crack extension (physical damage). Total energy absorbed to failure negatively correlated with average mineralization of the beam (r(2)=0.62), but not with notch root mineralization. Fracture initiation toughness was positively correlated to mineralization at the broken notch root (r(2)=0.34). Crack length extension at the unbroken notch was strongly negatively correlated with the average mineralization of the notch roots (r(2)=0.81) whereas crack length extension at the broken notch did not correlate with any of the mineralization measurements. Mineralization at the notch roots and the average mineralization contributed independently to the mechanical and damage properties. The data are consistent with a hypothesis that a) high notch root mineralization results in less stable crack length extension but high force to initiate unstable crack propagation while b) higher average mineralization leads to low post-yield (and total) energy absorption to failure.
Copyright © 2012 Elsevier Inc. All rights reserved.
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Publication Date: 2012-02-25 PubMed ID: 22394589PubMed Central: PMC4171132DOI: 10.1016/j.bone.2012.02.018Google Scholar: Lookup
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  • Journal Article
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  • N.I.H.
  • Extramural
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  • Non-U.S. Gov't

Summary

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The article presents research examining the effect of mineral content on the fracture properties of horse bone using a recently developed measurement method. The research suggests a relationship between mineralization around bone notches and fracture toughness and damage.

Research Methodology

  • The team used a new method developed for gauging the initiation toughness of cortical bone fractures. This method employs a double-notched beam in four-point bending.
  • The hypothesis under investigation was the correlation between the mineralization around the two notches of the bone and two aspects: fracture toughness and physical damage manifested as crack extension.

Findings

  • The total energy that was absorbed to cause failure was found to negatively correlate with the average mineralization of the beam, as shown by a correlation coefficient, r^2=0.62. However, this was not the case with the mineralization at the notch root.
  • There was a positive correlation between fracture initiation toughness and mineralization at the notch root where the break occurred, as evidenced by an r^2 value of 0.34.
  • A strong negative correlation was observed between the extension of the crack length at the unbroken notch and the average mineralization of the notch roots (r^2 score of 0.81).
  • The extension of the crack length at the broken notch did not have any correlation with the various mineralization measurements taken.

Conclusions

  • The average mineralization and the mineralization at the notch roots independently influenced the mechanical properties and the damage features of the equine bone.
  • The findings support a hypothesis that a) if the mineralization at the notch root is high, it lessens the stability of the crack length extension but requires more force to initiate unstable crack propagation, and b) higher average mineralization tends to reduce post-yield (and total) energy absorption to failure, effectively making the bone less resilient.

Cite This Article

APA
McCormack J, Stover SM, Gibeling JC, Fyhrie DP. (2012). Effects of mineral content on the fracture properties of equine cortical bone in double-notched beams. Bone, 50(6), 1275-1280. https://doi.org/10.1016/j.bone.2012.02.018

Publication

Bone
ISSN: 1873-2763
NlmUniqueID: 8504048
Country: United States
Language: English
Volume: 50
Issue: 6
Pages: 1275-1280

Researcher Affiliations

McCormack, Jordan
  • Department of Orthopaedic Surgery, University of California at Davis, Sacramento, CA, USA.
Stover, Susan M
    Gibeling, Jeffery C
      Fyhrie, David P

        MeSH Terms

        • Animals
        • Biomechanical Phenomena
        • Bone Density / physiology
        • Female
        • Fractures, Bone / pathology
        • Fractures, Bone / physiopathology
        • Fractures, Bone / veterinary
        • Horse Diseases / pathology
        • Horse Diseases / physiopathology
        • Horses
        • Microscopy, Electron, Scanning
        • Scattering, Radiation
        • Stress, Mechanical

        Grant Funding

        • R01 AR040776 / NIAMS NIH HHS
        • R01 AR040776-18 / NIAMS NIH HHS
        • AR040776 / NIAMS NIH HHS

        Conflict of Interest Statement

        None of the authors have any financial or personal relationships with other people or organizations that could inappropriately influence (bias) this work.

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        Citations

        This article has been cited 2 times.
        1. Bartlow CM, Mann KA, Damron TA, Oest ME. Limited field radiation therapy results in decreased bone fracture toughness in a murine model.. PLoS One 2018;13(10):e0204928.
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          doi: 10.1016/j.bone.2013.01.032pubmed: 23356988google scholar: lookup
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