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Home / Equine Research Bank / Front Microbiol / EHV-1: A Constant Threat to the Horse Industry.
Frontiers in microbiology2019; 10; 2668; doi: 10.3389/fmicb.2019.02668

EHV-1: A Constant Threat to the Horse Industry.

Abstract: Equine herpesvirus-1 (EHV-1) is one of the most important and prevalent viral pathogens of horses and a major threat to the equine industry throughout most of the world. EHV-1 primarily causes respiratory disease but viral spread to distant organs enables the development of more severe sequelae; abortion and neurologic disease. The virus can also undergo latency during which viral genes are minimally expressed, and reactivate to produce lytic infection at any time. Recently, there has been a trend of increasing numbers of outbreaks of a devastating form of EHV-1, equine herpesviral myeloencephalopathy. This review presents detailed information on EHV-1, from the discovery of the virus to latest developments on treatment and control of the diseases it causes. We also provide updates on recent EHV-1 research with particular emphasis on viral biology which enables pathogenesis in the natural host. The information presented herein will be useful in understanding EHV-1 and formulating policies that would help limit the spread of EHV-1 within horse populations.
Copyright © 2019 Oladunni, Horohov and Chambers.
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Publication Date: 2019-12-03 PubMed ID: 31849857PubMed Central: PMC6901505DOI: 10.3389/fmicb.2019.02668Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article focuses on Equine herpesvirus-1 (EHV-1), a harmful and prevalent virus in horses that causes respiratory issues along with potential abortions and neurologic ailments. The article reviews recent developments in controlling and treating diseases caused by EHV-1 and aims to aid in the formulation of policies to limit its spread.

Overview of EHV-1

  • The article begins with an overview of Equine herpesvirus-1 (EHV-1), stating its significant impact on the horse industry across the world. Describing it as one of the most prevalent viral pathogens of horses, it points out the primary symptom caused by the virus: respiratory disease. However, it also underscores the virus’s potential to lead to more severe conditions, such as abortion and neurological diseases in horses.

The Latency and Reactivation of EHV-1

  • The virus also exhibits a trait termed ‘latency’, in which the expression of viral genes is minimal. During this latency period, the virus remains dormant, but it can reactivate and reproduce lytic infection at any given time.

Increasing Outbreaks of Equine Herpesviral Myeloencephalopathy

  • The article draws attention to a worrying trend: an increase in outbreaks of a particularly destructive form of EHV-1, known as equine herpesviral myeloencephalopathy.

Developments in Treatment and Control of EHV-1

  • The review encapsulates detailed information on EHV-1, starting from its discovery up to the current advancements concerning the treatment and control of the diseases it inflicts.

Latest Research Updates on EHV-1

  • Special attention is brought to the recent research connected to EHV-1, more specifically the study of this virus’s biology that facilitates pathogenesis in the natural host.

Implication for Policy Formulation

  • The information presented in this research aims to feed into the understanding of EHV-1, contributing to the development of policies that can help limit and control the spread of EHV-1 among horse populations.

Cite This Article

APA
Oladunni FS, Horohov DW, Chambers TM. (2019). EHV-1: A Constant Threat to the Horse Industry. Front Microbiol, 10, 2668. https://doi.org/10.3389/fmicb.2019.02668

Publication

Frontiers in microbiology
ISSN: 1664-302X
NlmUniqueID: 101548977
Country: Switzerland
Language: English
Volume: 10
Pages: 2668
PII: 2668

Researcher Affiliations

Oladunni, Fatai S
  • Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, United States.
  • Department of Veterinary Microbiology, University of Ilorin, Ilorin, Nigeria.
Horohov, David W
  • Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, United States.
Chambers, Thomas M
  • Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, United States.

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