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The Veterinary clinics of North America. Equine practice2010; 26(2); 371-378; doi: 10.1016/j.cveq.2010.04.005

Endocrinopathic laminitis: reducing the risk through diet and exercise.

Abstract: Certain individual animals appear predisposed to recurrent pasture-associated laminitis, but the exact mechanisms underlying their predisposition remain a fundamental question in laminitis research. The risk of endocrinopathic laminitis can be reduced if steps are taken to improve insulin sensitivity and reduce inflammation using strategies based on exercise and diet. Exercise has been shown to reduce insulin resistance and suppress inflammation, and dietary manipulation can significantly affect insulin sensitivity.
Publication Date: 2010-06-09 PubMed ID: 20699181DOI: 10.1016/j.cveq.2010.04.005Google Scholar: Lookup
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Summary

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This research suggests that animals prone to repetitive laminitis, a painful and debilitating hoof disease, can have reduced risks of developing endocrinopathic laminitis if steps are taken to improve insulin sensitivity, reduce inflammation through appropriate diet and exercise.

Understanding Laminitis and Its Causes

  • This study focuses on endocrinopathic laminitis, a form of hoof disease common in horses. The precise mechanisms contributing to the susceptibility of certain animals to this disease is yet to be fully understood.

Improving Insulin Sensitivity

  • The ability of an animal’s body to use insulin effectively is a significant factor in the development of endocrinopathic laminitis. Hence, steps to improve insulin sensitivity can significantly reduce the risk of this disease.

The Role of Diet

  • The authors note that dietary manipulation has a substantial impact on insulin sensitivity. By adjusting an animal’s diet, the researchers suggest that insulin sensitivity might be significantly improved, thereby reducing the risk for laminitis.

Importance of Exercise

  • Exercise is another significant intervention suggested by the researchers. Exercise, in particular, has been demonstrated to lessen insulin resistance and mitigate inflammation, both of which are critical factors in the proliferation of endocrinopathic laminitis.

Implications of the Study

  • This research contributes to the existing knowledge on managing and reducing the risk of endocrinopathic laminitis among animals, especially those previously diagnosed with the condition. It provides feasible and easily implementable strategies such as diet modifications and regular exercise routines that could improve the overall wellbeing of such endangered animals.

Cite This Article

APA
Menzies-Gow NJ. (2010). Endocrinopathic laminitis: reducing the risk through diet and exercise. Vet Clin North Am Equine Pract, 26(2), 371-378. https://doi.org/10.1016/j.cveq.2010.04.005

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 26
Issue: 2
Pages: 371-378

Researcher Affiliations

Menzies-Gow, Nicola J
  • Department of Veterinary Clinical Science, Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire, UK. nmenziesgow@rvc.ac.uk

MeSH Terms

  • Animals
  • Diet / veterinary
  • Foot Diseases / prevention & control
  • Foot Diseases / veterinary
  • Hoof and Claw
  • Horse Diseases / prevention & control
  • Horses
  • Inflammation / prevention & control
  • Inflammation / veterinary
  • Physical Conditioning, Animal

Citations

This article has been cited 5 times.
  1. Kellon EM, Gustafson KM. Use of the SGLT2 inhibitor canagliflozin for control of refractory equine hyperinsulinemia and laminitis. Open Vet J 2022 Jul-Aug;12(4):511-518.
    doi: 10.5455/OVJ.2022.v12.i4.14pubmed: 36118716google scholar: lookup
  2. Norton E, Schultz N, Geor R, McFarlane D, Mickelson J, McCue M. Genome-Wide Association Analyses of Equine Metabolic Syndrome Phenotypes in Welsh Ponies and Morgan Horses. Genes (Basel) 2019 Nov 6;10(11).
    doi: 10.3390/genes10110893pubmed: 31698676google scholar: lookup
  3. Meier A, de Laat M, Reiche D, Fitzgerald D, Sillence M. The efficacy and safety of velagliflozin over 16 weeks as a treatment for insulin dysregulation in ponies. BMC Vet Res 2019 Feb 26;15(1):65.
    doi: 10.1186/s12917-019-1811-2pubmed: 30808423google scholar: lookup
  4. Bamford NJ, Potter SJ, Baskerville CL, Harris PA, Bailey SR. Influence of dietary restriction and low-intensity exercise on weight loss and insulin sensitivity in obese equids. J Vet Intern Med 2019 Jan;33(1):280-286.
    doi: 10.1111/jvim.15374pubmed: 30520164google scholar: lookup
  5. Meier A, Reiche D, de Laat M, Pollitt C, Walsh D, Sillence M. The sodium-glucose co-transporter 2 inhibitor velagliflozin reduces hyperinsulinemia and prevents laminitis in insulin-dysregulated ponies. PLoS One 2018;13(9):e0203655.
    doi: 10.1371/journal.pone.0203655pubmed: 30212530google scholar: lookup