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Veterinary journal (London, England : 1997)2024; 106249; doi: 10.1016/j.tvjl.2024.106249

Environmental Factors of Equine Osteochondrosis and Fetlock Osteochondral Fragments: A Scoping Review – Part 1.

Abstract: Various environmental and genetic risk factors are linked to the pathogenesis of equine osteochondrosis and osteochondral fragments in the fetlock joint. Therefore, a scoping review was conducted to describe current evidence linking genetic factors and environmental factors of these osteochondral disorders. This article constitutes the first part of this scoping review and focuses on environmental factors, with the second part addressing genetic factors. To identify potentially relevant papers online bibliographical databases PubMed and Web of Science were utilised, supplemented with articles listed on the OMIA website (OMIA:000750-9796). After entry collection, removing duplicates, screening titles, abstracts, and full-text documents for eligibility, and manually searching reference lists of the remaining articles, a total of 212 studies was identified for this scoping review. First, an overview of the current understanding of the etiopathogenesis of equine osteochondrosis and osteochondral fragments in the fetlock joint is given. Subsequently, the article delves into the environmental factors associated with the prevalence of these disorders, which are categorized into foetal programming, biomechanical trauma and exercise, growth, anatomic conformation, nutrition, weaning, hormonal factors, bacterial infection, sex, date of birth, and other environmental factors. In conclusion, future research should adopt a multidisciplinary approach, emphasizing longitudinal studies and precise phenotype definitions. This strategy will help elucidate the complex relationships between environmental factors and OC, DOF, and POF, considering the dynamic nature, varying phenotypes, and scarcity of research in some domains of these osteochondral disorders. This approach will be crucial in developing effective management strategies aimed at improving equine orthopaedic health.
Publication Date: 2024-09-27 PubMed ID: 39342984DOI: 10.1016/j.tvjl.2024.106249Google Scholar: Lookup
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Summary

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This research article is a comprehensive review of the environmental factors associated with osteochondral disorders in equines, specifically osteochondrosis and fetlock osteochondral fragments. It suggests that future research should consider a multidisciplinary approach to unravel the complex relationships between these disorders and environmental factors.

Introduction

  • The article is a scoping review that looks into the environmental and genetic factors related to equine osteochondrosis and osteochondral fragments in the fetlock joint.
  • The review uses various online databases such as PubMed, Web of Science, and articles from the OMIA website to gather relevant papers.
  • After a careful and rigorous process that involved removal of duplicates, screening titles, reviewing abstracts and full-text documents and manual search of reference lists, a total of 212 studies were identified for the review.

Etiopathogenesis of the Disorders

  • The research begins with an explanation of the current understanding of the cause and development of equine osteochondrosis and osteochondral fragments in the fetlock joint.
  • This aims to form a foundation for the subsequent discussion on the link between environmental factors and these disorders.

Environmental Factors

  • The study then deep-dives into the various environmental factors associated with these disorders, which include:
  • Foetal programming, biomechanical trauma and exercise, growth, anatomic conformation, nutrition, weaning, hormonal factors, bacterial infection, sex, date of birth, and other environmental factors.
  • Each of these factors is discussed in terms of how it affects the prevalence of the disorders.

Conclusions and Future Recommendations

  • The review concludes with a call for future research to take a multidisciplinary approach in investigating these disorders. It argues for the need for longitudinal studies and precise phenotype definitions to better understand the complex relationships between these factors and the disorders.
  • Furthermore, the authors argue that such an approach will be vital in developing effective management strategies that can enhance equine orthopaedic health.

Cite This Article

APA
Van Mol B, Oosterlinck M, Janssens S, Buys N, Pille F. (2024). Environmental Factors of Equine Osteochondrosis and Fetlock Osteochondral Fragments: A Scoping Review – Part 1. Vet J, 106249. https://doi.org/10.1016/j.tvjl.2024.106249

Publication

ISSN: 1532-2971
NlmUniqueID: 9706281
Country: England
Language: English
Pages: 106249
PII: S1090-0233(24)00188-6

Researcher Affiliations

Van Mol, B
  • Department of Large Animal Surgery, Anaesthesia and Orthopaedics, Faculty of Veterinary Medicine, Ghent University Salisburylaan 133, 9820 Merelbeke, Belgium; Center for Animal Breeding and Genetics, Department of Biosystems, KU Leuven, Kasteelpark Arenberg 30, 3001 Leuven, Belgium. Electronic address: bram.vanmol@ugent.be.
Oosterlinck, M
  • Department of Large Animal Surgery, Anaesthesia and Orthopaedics, Faculty of Veterinary Medicine, Ghent University Salisburylaan 133, 9820 Merelbeke, Belgium.
Janssens, S
  • Center for Animal Breeding and Genetics, Department of Biosystems, KU Leuven, Kasteelpark Arenberg 30, 3001 Leuven, Belgium.
Buys, N
  • Center for Animal Breeding and Genetics, Department of Biosystems, KU Leuven, Kasteelpark Arenberg 30, 3001 Leuven, Belgium.
Pille, F
  • Department of Large Animal Surgery, Anaesthesia and Orthopaedics, Faculty of Veterinary Medicine, Ghent University Salisburylaan 133, 9820 Merelbeke, Belgium.

Conflict of Interest Statement

Conflict of interest statement None of the authors of this paper has a financial or personal relationship with other people or organisations that could inappropriately influence or bias the content of the paper.

Citations

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