Equine Coronaviruses.
Abstract: Coronaviruses are a group of related RNA viruses that cause diseases in mammals and birds. In equids, equine coronavirus has been associated with diarrhea in foals and lethargy, fever, anorexia, and occasional gastrointestinal signs in adult horses. Although horses seem to be susceptible to the human severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) based on the high homology to the ACE-2 receptor, they seem to be incidental hosts because of occasional SARS-CoV-2 spillover from humans. However, until more clinical and seroepidemiological data are available, it remains important to monitor equids for possible transmission from humans with clinical or asymptomatic COVID-19.
Copyright © 2022 Elsevier Inc. All rights reserved.
Publication Date: 2022-11-21 PubMed ID: 36737293DOI: 10.1016/j.cveq.2022.11.008Google Scholar: Lookup
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Summary
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This research paper investigates the role of coronaviruses in horses, focusing particularly on potential susceptibility to SARS-CoV-2 (the virus that causes COVID-19 in humans) because of biological similarities. Evidence indicates that while horses could potentially be affected by the virus, they are likely incidental hosts, meaning that they do not typically spread the virus or become seriously ill.
Understanding Equine Coronaviruses
- The study explores coronaviruses, a class of RNA viruses, and their impact on horses.
- These viruses often result in ailments such as diarrhoea in young horses, while adult horses display different symptoms, including a lack of energy, fever, a loss of appetite, and various signs of gastrointestinal distress.
- The paper further identifies a particular type of coronavirus known as equine coronavirus, which mainly affects equids, a group of mammals consisting of horses and related animals.
Potential Susceptibility to SARS-CoV-2
- The research points out that horses may be susceptible to SARS-CoV-2, the virus responsible for COVID-19 in humans.
- This theory is based on the physiological similarities between the receptors in humans and horses that the virus docks onto.
- However, despite this potential vulnerability, the findings indicate that horses may not be a primary host for the virus.
Role of Horses in the Spread of the Virus
- The authors suggest that horses could be “incidental hosts” – creatures that can temporarily harbour a disease but do not continue its transmission.
- This is supported by the observation that horses appear to contract SARS-CoV-2 from humans in exceptional circumstances, rather than commonly spreading or falling severely ill from the virus.
- Despite these findings, the authors caution that more evidence is needed before definitive conclusions can be drawn.
- They stress the importance of continued observation of horses for potential transmission from humans who have either symptomatic or asymptomatic COVID-19.
Cite This Article
APA
Pusterla N.
(2022).
Equine Coronaviruses.
Vet Clin North Am Equine Pract, 39(1), 55-71.
https://doi.org/10.1016/j.cveq.2022.11.008 Publication
Researcher Affiliations
- Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA. Electronic address: npusterla@ucdavis.edu.
MeSH Terms
- Horses
- Animals
- Humans
- Betacoronavirus 1
- COVID-19 / veterinary
- SARS-CoV-2
- Horse Diseases
- Mammals
Citations
This article has been cited 6 times.- Stummer M, Frisch V, Glitz F, Hinney B, Spergser J, Krücken J, Diekmann I, Dimmel K, Riedel C, Cavalleri JV, Rümenapf T, Joachim A, Lyrakis M, Auer A. Presence of Equine and Bovine Coronaviruses, Endoparasites, and Bacteria in Fecal Samples of Horses with Colic. Pathogens 2023 Aug 15;12(8).
- Ricci I, Rosone F, Pacchiarotti G, Manna G, Cersini A, Carvelli A, La Rocca D, Cammalleri E, Giordani R, Tofani S, Conti R, Rombolà P, Nardini R, Minniti CA, Caforio R, Linardi B, Scicluna MT. Pegiviruses and Coronavirus: Biomolecular Prevalence and Phylogenetic Analysis of Strains Detected in Italian Horse Populations. Viruses 2025 Aug 2;17(8).
- Fukumoto N, Bannai H, Kawanishi N, Shibata M, Kishi D, Kambayashi Y, Tsujimura K, Nemoto M. The first outbreak of equine coronavirus infection in 13 years among draft horses at Obihiro Racecourse in Japan in 2025. J Vet Med Sci 2025 Oct 1;87(10):1158-1163.
- Pinn-Woodcock TL, Aprea MS, Lejeune M, Tomlinson JE. Molecular detection of pathogens in an equine fever diagnostic panel: 2019-2023. Equine Vet J 2026 Mar;58(2):486-496.
- Haywood LMB, Sheahan BJ. A Review of Epithelial Ion Transporters and Their Roles in Equine Infectious Colitis. Vet Sci 2024 Oct 7;11(10).
- Tyrnenopoulou P, Tsilipounidaki K, Florou Z, Gkountinoudis CG, Tyropoli K, Starras A, Peleki C, Marneris D, Arseniou N, Lianou DT, Katsarou EI, Petinaki E, Fthenakis GC. Detection of Gastrointestinal Pathogens with Zoonotic Potential in Horses Used in Free-Riding Activities during a Countrywide Study in Greece. Animals (Basel) 2024 Sep 3;14(17).
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