Omneity® Pellets
All-In-One Vitamin & Mineral Pellet
Equine Genotyping Arrays.
Abstract: High-quality genomic tools have been integral in understanding genomic architecture and function in the modern-day horse. The equine genetics community has a long tradition of pooling resources to develop genomic tools. Since the equine genome was sequenced in 2006, several iterations of high throughput genotyping arrays have been developed and released, enabling rapid and cost-effective genotyping. This review highlights the design considerations of each iteration, focusing on data available during development and outlining considerations in selecting the genetic variants included on each array. Additionally, we outline recent applications of equine genotyping arrays as well as future prospects and applications.
Copyright © 2020 Elsevier Inc. All rights reserved.
Publication Date: 2020-06-10 PubMed ID: 32534852DOI: 10.1016/j.cveq.2020.03.001Google Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Review
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This research article focuses on the development and use of genotyping arrays in equine genetics, highlighting different design considerations and future applications of these genomic tools.
Understanding Equine Genotyping Arrays
Genotyping arrays are tools used to detect variations in the genome of organisms. In the case of horses, these tools have been essential in understanding their genomic structure and function. These arrays have been developed and refined continuously since the sequencing of the equine genome in 2006.
- Genotyping arrays enable rapid and cost-effective genotyping, pivotal in progressing horse genomic studies.
- The equine genetics community has a collective approach to develop these genomic tools, in turn, driving significant advancements in this field.
Design Considerations
The design of each genotyping array iteration relies heavily on data available during development. These arrays need to be meticulously designed to include specific genetic variants to provide accurate and useful results.
- Early arrays may have been restricted to variants that were known at the time.
- As more data become available, new iterations of these arrays can include more variants and provide more comprehensive details about equine genomics.
The Use and Application of Genotyping Arrays
Equine genotyping arrays have been used in a wealth of genomic studies and have various applications.
- They have been utilized to improve our understanding of evolutionary pressures and adaptations of horses, as well as assisting in elucidating factors that contribute to genetic diseases and traits in different horse breeds.
Future Prospects and Applications
The possibilities for the future use and development of equine genotyping arrays are abundant.
- With the increasing refinement of these tools and accumulation of more data, researchers will be able to achieve even more detailed and nuanced understanding of equine genomics.
- This advancement in tools will likely assist in areas such as breeding strategies, disease prevention, and understanding the effects of genetic variation on horse health and performance.
Cite This Article
APA
Schaefer RJ, McCue ME.
(2020).
Equine Genotyping Arrays.
Vet Clin North Am Equine Pract, 36(2), 183-193.
https://doi.org/10.1016/j.cveq.2020.03.001 Publication
Researcher Affiliations
- Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, 1365 Gortner Avenue, St Paul, MN 55108, USA. Electronic address: schae234@umn.edu.
- Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, 1365 Gortner Avenue, St Paul, MN 55108, USA. Electronic address: https://twitter.com/Molly_McCue_DVM.
MeSH Terms
- Animals
- Genomics
- Genotype
- Genotyping Techniques / veterinary
- Horse Diseases / genetics
- Horses / genetics
- Polymorphism, Single Nucleotide
Conflict of Interest Statement
Disclosure This work was supported by USDA NIFA project 2012-67015-19432, Minnesota Agricultural Experiment Station Multi-state project MIN-62-090 and the National Animal Genome Project (NRSP8) through the equine genome coordinator: USDA-NRSP8 (2013-2018) horse-technical-committee coordinator funds. The funders had no role in the preparation of this manuscript.
Citations
This article has been cited 7 times.- Demyda-Peyrás S, Laseca N, Anaya G, Kij-Mitka B, Molina A, Karlau A, Valera M. Prevalence of Sex-Related Chromosomal Abnormalities in a Large Cohort of Spanish Purebred Horses. Animals (Basel) 2023 Feb 3;13(3).
- Reich P, Falker-Gieske C, Pook T, Tetens J. Development and validation of a horse reference panel for genotype imputation. Genet Sel Evol 2022 Jul 4;54(1):49.
- Wallis N, Raffan E. The Genetic Basis of Obesity and Related Metabolic Diseases in Humans and Companion Animals. Genes (Basel) 2020 Nov 20;11(11).
- Sharma M, Singh A, Kumar V, Olla N, Arora R, Sharma R, Mohan NH, Ahlawat S. Advances in Equine Genomics: Decoding the Genetic Architecture of Morphology, Performance, Behavior, and Adaptation. Mol Biotechnol 2025 Dec 19;.
- Ahlawat S, Niranjan SK, Arora R, Vijh RK, Kumar A, Sharma U, Raheja M, Popli K, Yadav S, Mehta SC. Advancing equine genomics: the development of a high density Axiom_Ashwa SNP chip for Indian horses and ponies. Funct Integr Genomics 2024 Oct 23;24(6):195.
- Lovász L, Sommer-Trembo C, Barth JMI, Scasta JD, Grancharova-Hill R, Lemoine RT, Kerekes V, Merckling L, Bouskila A, Svenning JC, Fages A. Rewilded horses in European nature conservation - a genetics, ethics, and welfare perspective. Biol Rev Camb Philos Soc 2025 Feb;100(1):407-427.
- De Coster T, Zhao Y, Tšuiko O, Demyda-Peyrás S, Van Soom A, Vermeesch JR, Smits K. Genome-wide equine preimplantation genetic testing enabled by simultaneous haplotyping and copy number detection. Sci Rep 2024 Jan 23;14(1):2003.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists
