Equine Squamous Gastric Disease: Prevalence, Impact and Management.
Abstract: This narrative review explores the etiopathogenesis, clinical signs, diagnosis and treatment of ESGD (equine squamous gastric disease) and discusses the impact of this commonly encountered condition on the equine industry. ESGD refers specifically to peptic injury of the squamous mucosa of the stomach. Prevalence is highest in performance horses, but the disease has been documented across many breeds and ages, including in feral horses and foals. The pathogenesis of ESGD is well understood. Intensive management and exercise are important factors that contribute to a disruption of the normal stratification of gastric pH. This results in exposure of the vulnerable squamous mucosa to acid, leading to ulceration. Clinical signs are variable and there is little evidence to support a direct association between reported signs and the presence or absence of lesions seen on gastroscopy. Management is aimed at acid suppression and mitigation of known risk factors.
© 2021 Hewetson and Tallon.
Publication Date: 2021-12-31 PubMed ID: 35004264PubMed Central: PMC8725839DOI: 10.2147/VMRR.S235258Google Scholar: Lookup
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Summary
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The research article explores the prevalence, impact, and management of Equine Squamous Gastric Disease (ESGD), a common health issue in horses associated with peptic injury of the stomach’s squamous mucosa.
Etio-pathogenesis of ESGD
- The study delves into the causes and progression of ESGD, a disease that largely affects performance horses, but is not limited to this group, as it is also found in various other breeds, ages, and even in feral horses and foals.
- The pathogenesis, or the biological mechanism that leads to the disease, is quite well understood. It is often linked to intensive horse management and training processes that disrupt the normal gastric pH stratification. This disruption results in the exposure of the squamous mucosa (a delicate lining in the stomach) to acid, which in turn prompts ulceration.
Clinical Signs and Diagnosis
- Identifying clear clinical signs of ESGD proves challenging as symptoms are variable, and there is currently insubstantial evidence to draw a direct correlation between reported signs and the presence or absence of lesions observable through a gastroscopy (medical examination of the stomach).
Management and Treatment
- The research emphasizes the importance of managing known risk factors and suppressing acid levels as a means of handling ESGD. Specific treatment methodologies or strategies are not expanded on in the abstract, but we can infer that they would entail changes in horse care routines and may likely involve therapeutic interventions focused on pH levels.
Impact on the Equine Industry
- The condition, given its relatively high prevalence, especially among performance horses, has a significant impact on the equine industry. The study aims to explore this impact further, although details are not provided in the abstract.
Cite This Article
APA
Hewetson M, Tallon R.
(2021).
Equine Squamous Gastric Disease: Prevalence, Impact and Management.
Vet Med (Auckl), 12, 381-399.
https://doi.org/10.2147/VMRR.S235258 Publication
Researcher Affiliations
- Department of Clinical Science and Services, The Royal Veterinary College, North Mymms, Hertfordshire, UK.
- Department of Clinical Science and Services, The Royal Veterinary College, North Mymms, Hertfordshire, UK.
Conflict of Interest Statement
The authors report no conflicts of interest in this work.
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