Evaluation of equine breeding farm management and preventative health practices as risk factors for development of Rhodococcus equi pneumonia in foals.
Abstract: To determine whether foal management practices, environmental management, and preventative health practices are risk factors for development of Rhodococcus equi pneumonia in foals. Methods: Prospective matched case-control study. Methods: 2,764 foals on 64 equine breeding farms with 9,991 horses. Methods: During 1997, participating veterinarians completed paired data collection forms for comparison; 1 for an affected farm (containing > or = 1 foal with pneumonia caused by R equi) and 1 for a control farm. Information collected pertained to stabling facilities, environmental management, foal husbandry, and preventative equine health practices. Results: Matched farm data compared by use of conditional logistic regression indicated that personnel on affected farms were more likely to attend foal births, test foals for adequacy of passive immunity, administer plasma or other treatments to foals to supplement serum immunoglobulin concentrations, administer hyperimmune plasma prophylactically to foals, vaccinate mares and foals against Streptococcus equi infection, and use multiple anthelmintics in deworming programs. Affected farms were also more likely to have foals that developed other respiratory tract disorders and were approximately 4 times as likely to have dirt floors in stalls used for housing foals as were control farms. Conclusions: Rhodococcus equi pneumonia does not appear to be associated with poor farm management or a lack of attention to preventative health practices. Housing foals in stalls with dirt floors may increase the risk for development of R equi pneumonia.
Publication Date: 2003-02-25 PubMed ID: 12597421DOI: 10.2460/javma.2003.222.476Google Scholar: Lookup
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- Evaluation Study
- Journal Article
- Research Support
- Non-U.S. Gov't
- Research Support
- U.S. Gov't
- Non-P.H.S.
Summary
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This study investigates the relationship between the management of equine breeding farms and the preventative health practices with the occurrence of Rhodococcus equi pneumonia in foals. The research suggests that this type of pneumonia is not necessarily linked to poor farm management or insightfulness in health practices, but the use of dirt floors in foal stalls could potentially elevate the risk of developing this illness.
Research Methodology
- With the ambition of discovering whether foal rearing practices, environmental management, and preventative health care are risk factors for Rhodococcus equi pneumonia, researchers initiated a prospective matched case-control study.
- The study encompassed 2,764 foals on 64 equine breeding farms housing a total of 9,991 horses.
- The research was conducted over the course of 1997, during which veterinarians completed data collection forms on both affected farms (those having one or more foals diagnosed with Rhodococcus equi pneumonia) and control farms.
- Data collected pertained to elements including stabling facilities, environmental management, foal husbandry, and preventative equine health practices.
Research Findings
- Through conditional logistic regression comparison of matched farm data, it was revealed that personnel on affected farms were more inclined to be present at foal births, test foals for adequacy of passive immunity, administer plasma or other treatments to boost serum immunoglobulin concentrations, and provide vaccinations against Streptococcus equi infection for mares and foals.
- Furthermore, farms where the pneumonia condition occurred were more likely to apply multiple anthelmintics in their deworming programs and record other respiratory tract disorders among the foals.
- One of the standout findings was that foals in affected farms were roughly four times as likely to be housed in stalls with dirt floors compared to control farms.
Conclusion
- The report concludes that development of Rhodococcus equi pneumonia in foals does not necessarily correlate with poor farm management or negligence in preventative health measures.
- The single environmental factor that appeared to have a significant connection to the disease was the use of dirt floors in foal housing stalls, as this was found to potentially increase the likelihood of the pneumonia occurring.
Cite This Article
APA
Chaffin MK, Cohen ND, Martens RJ.
(2003).
Evaluation of equine breeding farm management and preventative health practices as risk factors for development of Rhodococcus equi pneumonia in foals.
J Am Vet Med Assoc, 222(4), 476-485.
https://doi.org/10.2460/javma.2003.222.476 Publication
Researcher Affiliations
- Department of Large Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843-4475, USA.
MeSH Terms
- Actinomycetales Infections / epidemiology
- Actinomycetales Infections / etiology
- Actinomycetales Infections / prevention & control
- Actinomycetales Infections / veterinary
- Animal Husbandry / methods
- Animals
- Animals, Newborn
- Breeding
- Case-Control Studies
- Female
- Horse Diseases / epidemiology
- Horse Diseases / etiology
- Horse Diseases / prevention & control
- Horses
- Housing, Animal / standards
- Male
- Pneumonia, Bacterial / epidemiology
- Pneumonia, Bacterial / etiology
- Pneumonia, Bacterial / prevention & control
- Pneumonia, Bacterial / veterinary
- Prospective Studies
- Respiratory Tract Infections / epidemiology
- Respiratory Tract Infections / etiology
- Respiratory Tract Infections / prevention & control
- Respiratory Tract Infections / veterinary
- Rhodococcus equi
- Risk Factors
Citations
This article has been cited 7 times.- Rakowska A, Czopowicz M, Bereznowski A, Witkowski L. Investigation of the relationship between pulmonary lesions based on lung ultrasound and respiratory clinical signs in foals with suspected pulmonary rhodococcosis. Sci Rep 2023 Nov 8;13(1):19401.
- Cohen ND, Kahn SK, Bordin AI, Gonzales GM, da Silveira BP, Bray JM, Legere RM, Ramirez-Cortez SC. Association of pneumonia with concentrations of virulent Rhodococcus equi in fecal swabs of foals before and after intrabronchial infection with virulent R. equi. J Vet Intern Med 2022 May;36(3):1139-1145.
- Cohen ND, Kahn SK, Cywes-Bentley C, Ramirez-Cortez S, Schuckert AE, Vinacur M, Bordin AI, Pier GB. Serum Antibody Activity against Poly-N-Acetyl Glucosamine (PNAG), but Not PNAG Vaccination Status, Is Associated with Protecting Newborn Foals against Intrabronchial Infection with Rhodococcus equi. Microbiol Spectr 2021 Sep 3;9(1):e0063821.
- Rakowska A, Cywinska A, Witkowski L. Current Trends in Understanding and Managing Equine Rhodococcosis. Animals (Basel) 2020 Oct 18;10(10).
- Aslam MW, Lau SF, Chin CSL, Ahmad NI, Rahman NA, Kuppusamy K, Omar S, Radzi R. Clinicopathological and radiographic features in 40 cats diagnosed with pulmonary and cutaneous Rhodococcus equi infection (2012-2018). J Feline Med Surg 2020 Aug;22(8):774-790.
- Flaminio MJ, Nydam DV, Marquis H, Matychak MB, Giguère S. Foal monocyte-derived dendritic cells become activated upon Rhodococcus equi infection. Clin Vaccine Immunol 2009 Feb;16(2):176-83.
- Cohen ND, Harrington J, Gros P, Del Castro L, Meyer D, Martens RJ. Nramp1 deletion does not confer susceptibility to Rhodococcus equi infection in mice. Immunogenetics 2004 Apr;56(1):65-7.
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