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The Canadian veterinary journal = La revue veterinaire canadienne2021; 62(7); 729-735;

Evaluation of platelet-rich plasma applied in the coronary band of healthy equine hooves.

Abstract: Platelet-rich plasma (PRP) is a widely used hemocomponent that holds great promise in equine medicine due to its feasible production and regenerative therapy potential. Its use has been considered as a treatment for chronic laminitis, mainly in terms of its analgesic properties and because it can induce growth in affected hooves. The aim of this study was to evaluate the effect on hoof growth attributable to PRP applied in the coronary band of clinically healthy horses by comparing the responses to PRP, saline, and trimming alone. After randomization, the forelimbs of 9 horses received specific treatment at intervals of 33 days and were trimmed, measured, and radiographed at the same time. Neither hoof growth nor hoof angles were different between the treatment groups at any time point. The application of PRP in the coronary band of horses may be a safe procedure; however, it had no effect on the growth or conformation of hooves in clinically healthy horses. Évaluation du plasma riche en plaquettes appliqué dans la bande coronaire de sabots équins sains. Le plasma riche en plaquettes (PRP) est un hémo-composant largement utilisé qui est très prometteur en médecine équine en raison de sa production réalisable et de son potentiel de thérapie régénérative. Son utilisation a été considérée comme un traitement de la fourbure chronique, principalement en termes de ses propriétés analgésiques et parce qu’elle peut induire la croissance des sabots atteints. Le but de cette étude était d’évaluer l’effet sur la croissance des sabots attribuable au PRP appliqué dans la bande coronaire de chevaux cliniquement sains en comparant les réponses au PRP, à la solution saline et à la taille seule. Après randomisation, les membres antérieurs de neuf chevaux ont reçu un traitement spécifique à des intervalles de 33 jours et ont été taillés, mesurés et radiographiés au même moment. Ni la croissance ni les angles des sabots n’étaient différents entre les groupes de traitement à aucun moment. L’application de PRP dans la bande coronaire des chevaux peut être une procédure sûre; cependant, il n’a eu aucun effet sur la croissance ou la conformation des sabots chez les chevaux cliniquement sains.(Traduit par Dr Serge Messier).
Copyright and/or publishing rights held by the Canadian Veterinary Medical Association.
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Publication Date: 2021-07-06 PubMed ID: 34219782PubMed Central: PMC8218955
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article examines the impact of platelet-rich plasma (PRP) application on the hoof growth of healthy horses, comparing the effects to saline treatment and trimming alone. The study concludes that while PRP application is safe, it does not influence hoof growth or shape.

Background & Aim

  • The researchers focus on studying the impact of the use of platelet-rich plasma (PRP) in equine medicine, as it’s a readily produced hemocomponent with potential for regenerative therapy.
  • PRP has been seen as a possible treatment for chronic laminitis in horses, credited for its analgesic properties and its perceived ability to induce growth in affected hooves.
  • The aim of the study is to assess the effect of PRP on hoof growth when applied to the coronary band of healthy horses and compare this with the response to saline application and trimming alone.

Methodology

  • The forelimbs of 9 randomly chosen healthy horses were the focus of the experiment.
  • These horses underwent specific treatments (PRP, saline, or trimming alone) every 33 days, and at the same time their hooves were measured, trimmed, and radiographed.

Findings

  • No difference was noted in either hoof growth or hoof angles among the different treatment groups at any point during the trial.

Conclusions

  • While the researchers concluded that applying PRP to the coronary band of horses is a safe procedure, they found that it did not have an impact either on the growth or the conformation of hooves in healthy horses.
  • Thus, while PRP might have promise for certain aspects of equine medicine, it does not seem to deliver benefits in terms of promoting hoof growth or changing hoof shape.

Cite This Article

APA
Seidel SRT, de Souza AF, Fülber J, Bogossian PM, Rodrigues NNP, Baccarin RYA. (2021). Evaluation of platelet-rich plasma applied in the coronary band of healthy equine hooves. Can Vet J, 62(7), 729-735.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 62
Issue: 7
Pages: 729-735

Researcher Affiliations

Seidel, Sarah Raphaela Torquato
  • Departamento de Clínica Veterinária (Seidel, Bogossian, Rodrigues, Baccarin), Departamento de Cirurgia Veterinária (de Souza, Fülber) Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 05508-270, Brazil.
de Souza, Anderson Fernando
  • Departamento de Clínica Veterinária (Seidel, Bogossian, Rodrigues, Baccarin), Departamento de Cirurgia Veterinária (de Souza, Fülber) Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 05508-270, Brazil.
Fülber, Joice
  • Departamento de Clínica Veterinária (Seidel, Bogossian, Rodrigues, Baccarin), Departamento de Cirurgia Veterinária (de Souza, Fülber) Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 05508-270, Brazil.
Bogossian, Paulo Moreira
  • Departamento de Clínica Veterinária (Seidel, Bogossian, Rodrigues, Baccarin), Departamento de Cirurgia Veterinária (de Souza, Fülber) Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 05508-270, Brazil.
Rodrigues, Nubia Nayara Pereira
  • Departamento de Clínica Veterinária (Seidel, Bogossian, Rodrigues, Baccarin), Departamento de Cirurgia Veterinária (de Souza, Fülber) Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 05508-270, Brazil.
Baccarin, Raquel Yvonne Arantes
  • Departamento de Clínica Veterinária (Seidel, Bogossian, Rodrigues, Baccarin), Departamento de Cirurgia Veterinária (de Souza, Fülber) Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 05508-270, Brazil.

MeSH Terms

  • Animals
  • Forelimb
  • Hoof and Claw
  • Horse Diseases / diagnostic imaging
  • Horses
  • Platelet-Rich Plasma
  • Radiography

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Citations

This article has been cited 1 times.
  1. Bernardini C, Romagnoli N, Casalini I, Turba ME, Spadari A, Forni M, Gentilini F. Freeze-drying protocols and methods of maintaining the in-vitro biological activity of horse platelet lysate. Int J Vet Sci Med 2024;12(1):71-80.
    doi: 10.1080/23144599.2024.2380586pubmed: 39119550google scholar: lookup
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