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The Canadian veterinary journal = La revue veterinaire canadienne2007; 48(6); 627-629;

Fatal brodifacoum poisoning in a pony.

Abstract: Fatal brodifacoum poisoning in a pony is described; this condition has not previously been reported in ponies. Discussion of what factors in the pony's history and treatment may have predisposed to the severity and ultimate death is provided. Cet article décrit un empoisonnement mortel au brodifacoum chez un poney, condition jamais rapportée auparavant. La discussion porte sur les liens entre les divers éléments de l’anamnèse et les traitements reçus par rapport à la sévérité de la condition et ultimement à la mort de l’animal. (Traduit par Docteur André Blouin)
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Publication Date: 2007-07-10 PubMed ID: 17616062PubMed Central: PMC1876195
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study discusses a case of fatal brodifacoum poisoning in a pony, the first of its kind ever reported. The paper provides an analysis of the pony’s medical history and treatment that may have contributed to the severity of the condition and ultimately, the death of the animal.

Background of the Research

  • This research revolves around a case of brodifacoum poisoning in a pony, an occurrence not documented before.
  • Brodifacoum is a highly lethal anticoagulant which is often used as a rodenticide. This substance leads to uncontrolled bleeding, which can result in death if not treated promptly and correctly.

Objective of the Research

  • The primary goal of this research is to detail the findings of this case to highlight the potential dangers of brodifacoum poisoning in animals, specifically in ponies.
  • It also aims to analyze the factors, including the pony’s history and administered treatments, that may have contributed to the catastrophic outcome.

Key Findings of the Research

  • The study reports lethal brodifacoum toxicity in a pony, marking it as a significant health hazard for equine populations, given the commonality of brodifacoum usage in pest control.
  • It is inferred that the pony might have accidentally consumed a product containing brodifacoum, leading to poisoning.
  • The severity of the condition and the eventual death of the pony may link to specific elements in the pony’s history, treatments received, or possibly the individual susceptibility of the pony to brodifacoum toxicity. These factors are explored and discussed in detail.

Significance of the Research

  • This research serves as a vital reference for equine health practitioners, who may encounter similar cases in the future.
  • It helps to build a broader understanding of brodifacoum toxicity in different species, thereby contributing to improved prevention, diagnosis, and treatment strategies in veterinary medicine.

Cite This Article

APA
Ayala I, Rodríguez MJ, Martos N, Zilberschtein J, Ruíz I, Motas M. (2007). Fatal brodifacoum poisoning in a pony. Can Vet J, 48(6), 627-629.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 48
Issue: 6
Pages: 627-629

Researcher Affiliations

Ayala, Ignacio
  • Large Animal Medicine and Surgery Service, Clinical Veterinary Hospital, University of Murcia, Campus de Espinardo s/n, Murcia 30100, Spain. iayape@um.es
Rodríguez, Ma Jesús
    Martos, Nieves
      Zilberschtein, José
        Ruíz, Isidro
          Motas, Miguel

            MeSH Terms

            • 4-Hydroxycoumarins / poisoning
            • Animals
            • Anticoagulants / poisoning
            • Fatal Outcome
            • Female
            • Hemorrhage / chemically induced
            • Hemorrhage / pathology
            • Hemorrhage / veterinary
            • Horse Diseases / chemically induced
            • Horse Diseases / pathology
            • Horses
            • Rodenticides / poisoning

            References

            This article includes 10 references
            1. Leck JB, Park BK. A comparative study of the effects of warfarin and brodifacoum on the relationship between vitamin K1 metabolism and clotting factor activity in warfarin-susceptible and warfarin-resistant rats.. Biochem Pharmacol 1981 Jan 15;30(2):123-8.
              pubmed: 7236301doi: 10.1016/0006-2952(81)90182-9google scholar: lookup
            2. McConnico RS, Copedge K, Bischoff KL. Brodifacoum toxicosis in two horses.. J Am Vet Med Assoc 1997 Oct 1;211(7):882-6.
              pubmed: 9333092
            3. Scott EA, Sandler GA, Byars TD. Warfarin: effects on anticoagulant, hematologic, and blood enzyme values in normal ponies.. Am J Vet Res 1979 Jan;40(1):142-6.
              pubmed: 453677
            4. Boermans HJ, Johnstone I, Black WD, Murphy M. Clinical signs, laboratory changes and toxicokinetics of brodifacoum in the horse.. Can J Vet Res 1991 Jan;55(1):21-7.
              pmc: PMC1263408pubmed: 1884280
            5. Scott EA, Sandler GA, Byars TD. Warfarin: effects of intravenous loading doses and vitamin K on warfarin anticoagulation in the pony.. Am J Vet Res 1978 Dec;39(12):1888-91.
              pubmed: 749570
            6. Rengel I, Friedrich A. Detection of anticoagulant rodenticides (4-hydroxycoumarins) by thin-layer chromatography and reversed-phase high-performance liquid chromatography with fluorescence detection.. Vet Res Commun 1993;17(6):421-7.
              pubmed: 8030196doi: 10.1007/bf01839210google scholar: lookup
            7. Robinson NE. Current Therapy in Equine Medicine 5. Missouri: Saunders Elsevier Science, 2003:354.
            8. Reed SM, Bayly WM, Sellon DC. Equine Internal Medicine, 2nd ed. Missouri: Saunders Elsevier, 2004:1481–1483.
            9. Vrins A, Carlson G, Feldman B. Warfarin: a review with emphasis on its use in the horse.. Can Vet J 1983 Jul;24(7):211-3.
              pmc: PMC1790352pubmed: 17422277
            10. Booth NH, McDonald LE. Veterinary Pharmacology and Therapeutics, 6th ed. Ames: Iowa State University Press, 1988:482–494.

            Citations

            This article has been cited 5 times.
            1. Rached A, Moriceau MA, Serfaty X, Lefebvre S, Lattard V. Biomarkers Potency to Monitor Non-target Fauna Poisoning by Anticoagulant Rodenticides. Front Vet Sci 2020;7:616276.
              doi: 10.3389/fvets.2020.616276pubmed: 33426034google scholar: lookup
            2. Satué K, Gardon JC, Muñoz A. Clinical and laboratorial description of the differential diagnoses of hemostatic disorders in the horse. Iran J Vet Res 2020 Winter;21(1):1-8.
              pubmed: 32368218
            3. Zakian A, Mami S, Nouri M, Jalali SM, Tehrani-Sharif M. Brodifacoum toxicosis and abortion in an Arabian mare. Vet Res Forum 2019 Spring;10(2):173-176.
              doi: 10.30466/vrf.2018.85534.2115pubmed: 31338153google scholar: lookup
            4. Ma M, Zhang M, Tang X, Li Z. Massive neonatal intracranial hemorrhage caused by bromadiolone: A case report. Medicine (Baltimore) 2017 Nov;96(45):e8506.
              doi: 10.1097/MD.0000000000008506pubmed: 29137047google scholar: lookup
            5. Furness MC, Setlakwe E, Sallaway J, Wood D, Fromstein J, Arroyo LG. Acute myeloid leukemia with basophilic differentiation in a 3-year-old Standardbred gelding. Can Vet J 2016 Oct;57(10):1067-1071.
              pubmed: 27708445
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