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Hypertrophic osteopathy in three horses and a pony.

Abstract: Hypertrophic osteopathy was diagnosed in 3 horses and in a pony, ranging in age from 8 to 21 years. There were 2 females, 1 sexually intact male, and 1 gelding. In 3 animals, hypertrophic osteopathy was associated with pulmonary abscesses, bronchogenic squamous cell carcinoma, and ovarian granulosa-cell tumor, respectively, and resulted in death or euthanasia. Duration of the condition ranged from 1 to 4 months. In 1 horse, hypertrophic osteopathy was believed to be secondary to pregnancy, and resolved following uncomplicated delivery of a live foal.
Publication Date: 1992-12-15 PubMed ID: 1483912
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Summary

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This research focuses on the study of hypertrophic osteopathy in three adult horses and a pony, its association with various health conditions, and its resolution in one case following pregnancy and delivery.

Outline of the Research

  • The study centered around investigating the condition of hypertrophic osteopathy that occurred in three horses and a pony, which were between 8 and 21 years of age. Hypertrophic osteopathy is a rare condition in equines, characterized by a symmetric, painful swelling of the periosteum, the membrane that covers the bones.
  • The test subjects composed of two female horses, one male horse, and one gelding, which is a castrated male horse.

Association with Health Conditions

  • In this study, it was found that three animals (two horses and a pony) had hypertrophic osteopathy associated with distinct health conditions, varying from pulmonary abscesses, bronchogenic squamous cell carcinoma to ovarian granulosa-cell tumor.
  • Pulmonary abscesses are localized pockets of pus in the lungs, bronchogenic squamous cell carcinoma is a type of lung cancer that begins in the bronchi and involves squamous cells, and ovarian granulosa-cell tumor is a type of tumor that occurs in the granulosa cells, which are part of the ovaries in females. All of these are serious health issues which resulted in either natural death or euthanasia of the animals.
  • The condition lasted from one month up to four months in these animals.

Resolution of Hypertrophic Osteopathy Post Pregnancy

  • In one of the horses, hypertrophic osteopathy was observed during its pregnancy and the condition resolved itself after the horse delivered a healthy foal.
  • This indicates that the hypertrophic osteopathy might have been a secondary condition arising due to the pregnancy in this particular case, reinforcing the complex and varying nature of this disease.

Cite This Article

APA
Lavoie JP, Carlson GP, George L. (1992). Hypertrophic osteopathy in three horses and a pony. J Am Vet Med Assoc, 201(12), 1900-1904.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 201
Issue: 12
Pages: 1900-1904

Researcher Affiliations

Lavoie, J P
  • Département de Médecine, Faculté de Médecine Vétérinaire, Université de Montréal, St Hyacinthe, PQ, Canada.
Carlson, G P
    George, L

      MeSH Terms

      • Animals
      • Carcinoma, Bronchogenic / complications
      • Carcinoma, Bronchogenic / veterinary
      • Carcinoma, Squamous Cell / complications
      • Carcinoma, Squamous Cell / veterinary
      • Female
      • Granulosa Cell Tumor / complications
      • Granulosa Cell Tumor / veterinary
      • Horse Diseases / etiology
      • Horses
      • Lung Abscess / complications
      • Lung Abscess / veterinary
      • Lung Neoplasms / complications
      • Lung Neoplasms / veterinary
      • Male
      • Osteoarthropathy, Secondary Hypertrophic / etiology
      • Osteoarthropathy, Secondary Hypertrophic / veterinary
      • Ovarian Neoplasms / complications
      • Ovarian Neoplasms / veterinary
      • Pregnancy
      • Pregnancy Complications / etiology
      • Pregnancy Complications / veterinary
      • Pregnancy Complications, Neoplastic / veterinary

      Citations

      This article has been cited 2 times.
      1. Browne NS, Scarratt WK, Robertson J. Hypertrophic osteopathy secondary to metastatic ovarian adenocarcinoma in a mare. Can Vet J 2016 Dec;57(12):1237-1241.
        pubmed: 27928168
      2. Weyna AAW, Luley E, Brown JD, Niedringhaus KD, Gibbs SEJ, Nemeth NM. Hypertrophic osteopathy in 4 white-tailed deer, with a literature review. J Vet Diagn Invest 2025 Mar;37(2):340-344.
        doi: 10.1177/10406387251318413pubmed: 39910747google scholar: lookup