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The Veterinary clinics of North America. Equine practice1986; 2(2); 395-402; doi: 10.1016/s0749-0739(17)30724-1

Immunity and potential of vaccination.

Abstract: This article will focus on current information available on the equine immune response to helminth parasites as it relates to acquired resistance, hypersensitivity reactions, and vaccine development.
Publication Date: 1986-08-01 PubMed ID: 3527379DOI: 10.1016/s0749-0739(17)30724-1Google Scholar: Lookup
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Summary

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The research article discusses the immune response of horses to worm parasites, considering the development of resistance, allergic responses, and the possibilities for vaccine development.

About the Immune Response of Horses

  • The immune response of horses to worm parasites is an important area of study in equine health. Horses can develop an immune response to these parasites, which can either result in the development of resistance, leading to healthier future interactions with the parasites, or can lead to hypersensitivity reactions.
  • Hypersensitivity reactions are similar to allergic reactions, where the horse’s body reacts too strongly to the parasite, causing health issues.

Acquired Resistance and Hypersensitivity Reactions

  • Acquired resistance to parasites is when a horse has been exposed to a parasite and its body has developed defenses to deal with future infections. This is a positive outcome, as it enables the horse to resist future infections from the same parasite.
  • However, in some cases, the horse’s immune response may be excessive, leading to hypersensitivity reactions. These reactions can cause a variety of health problems, ranging from moderate to severe. The study explores these hypersensitivity reactions in detail, explaining how they occur and some of the potential treatments for them.

Vaccine Development

  • One of the main focuses of the article is on the potential of vaccine development. The researchers explore how understanding the horse’s immune response to worm parasites could aid in the development of vaccines to protect against these infections.
  • They talk about current advancements in this area and the challenges still faced by scientists in creating an effective and safe vaccine. The study provides valuable insights into the intricacies of vaccine development, highlighting the important connection between fundamental immune response research and practical applications in the field of equine health.

Cite This Article

APA
Klei TR. (1986). Immunity and potential of vaccination. Vet Clin North Am Equine Pract, 2(2), 395-402. https://doi.org/10.1016/s0749-0739(17)30724-1

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 2
Issue: 2
Pages: 395-402

Researcher Affiliations

Klei, T R

    MeSH Terms

    • Animals
    • Ascariasis / veterinary
    • Helminthiasis / immunology
    • Helminthiasis / prevention & control
    • Helminthiasis, Animal
    • Horse Diseases / immunology
    • Horse Diseases / prevention & control
    • Horses
    • Intestinal Diseases, Parasitic / veterinary
    • Nematode Infections / veterinary
    • Strongyle Infections, Equine / immunology
    • Vaccination

    Citations

    This article has been cited 1 times.
    1. Jasmer DP, McGuire TC. Protective immunity to a blood-feeding nematode (Haemonchus contortus) induced by parasite gut antigens. Infect Immun 1991 Dec;59(12):4412-7.