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Inflammatory airway disease of horses.
Abstract: The purpose of this consensus statement is to provide a review of current knowledge and opinions concerning inflammatory airway disease (IAD) and to help practitioners differentiate IAD from heaves (or recurrent airway obstruction; RAO) and other inflammatory respiratory diseases of horses.
Publication Date: 2007-04-13 PubMed ID: 17427403DOI: 10.1892/0891-6640(2007)21[356:iadoh]2.0.co;2Google Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Consensus Development Conference
- Journal Article
- Clinical Findings
- Clinical Study
- Clinical Symptoms
- Diagnosis
- Disease
- Disease Diagnosis
- Disease Etiology
- Disease Management
- Disease Treatment
- Equine Diseases
- Equine Health
- Horses
- Infection
- Inflammation
- Inflammatory Response
- Pathogenesis
- Pathology
- Recurrent Airway Obstruction
- Respiratory Disease
- Veterinary Care
- Veterinary Medicine
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This research article intends to present an overview and current understanding of inflammatory airway disease (IAD) in horses. It aims to assist practitioners in distinguishing IAD from similar inflammatory respiratory conditions, such as recurrent airway obstruction (RAO), and various other respiratory diseases seen in horses.
Introduction and Overview
This consensus statement offers an evaluation of the latest information and perspectives on inflammatory airway disease (IAD). IAD, a common health issue in horses, often results in inflammation of the horse’s airway and can impact their performance. The study aims to make it easier for veterinarians and horse professionals to identify and distinguish IAD from other similar respiratory diseases like recurrent airway obstruction (RAO) and other types of inflammatory respiratory issues horses can face.
The Challenge in Diagnosis
- One of the major difficulties lies in diagnosing IAD, mainly because it demonstrates similar symptoms to other respiratory diseases in horses. Symptoms can often include coughing, nasal discharge, and difficulty in breathing.
- The study tries to provide distinctive points of different diagnosis to assist veterinarians in avoiding misdiagnosis. The wrong diagnosis can lead to ineffective treatment regimes and hence, can harm equine health in the long run.
Insight into IAD and RAO
- The paper discusses the differences between IAD and recurrent airway obstruction (RAO). While they both are respiratory diseases, they differ in terms of causative factors, symptoms and treatment procedures.
- Understanding these differences can guide pharmaceutical companies to design more specific drugs and treatment strategies for each condition, thereby increasing the efficiency and effectiveness of these interventions.
Conclusion and Recommendations
- The consensus statement concludes by suggesting guidelines for recognizing and treating IAD effectively. The authors recommend a consistent method of diagnosing and treating IAD to guarantee consistent and improved health outcomes for horses.
- This research is essential as it offers a more clear understanding of IAD, its distinctiveness from other diseases, and a consistent way to treat and manage the condition.
Cite This Article
APA
Couu00ebtil LL, Hoffman AM, Hodgson J, Buechner-Maxwell V, Viel L, Wood JL, Lavoie JP.
(2007).
Inflammatory airway disease of horses.
J Vet Intern Med, 21(2), 356-361.
https://doi.org/10.1892/0891-6640(2007)21[356:iadoh]2.0.co;2 Publication
Researcher Affiliations
- Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN, USA. couetill@purdue.edu
MeSH Terms
- Animal Husbandry
- Animals
- Bronchodilator Agents / therapeutic use
- Horse Diseases / diagnosis
- Horse Diseases / therapy
- Horses
- Lung Diseases / diagnosis
- Lung Diseases / therapy
- Lung Diseases / veterinary
Citations
This article has been cited 48 times.- Al-Ali MA, Shawaf T. Effect of age, season, and gender on bronchoalveolar lavage fluid cytology in camels.. Open Vet J 2023 May;13(5):550-557.
- Dobiu00e1u0161 R, Jahn P, Tu00f3thovu00e1 K, Dobeu0161ovu00e1 O, Viu0161u0148ovsku00e1 D, Patil R, u0160kru00edba A, Jaworsku00e1 P, u0160koriu010d M, Podojil L, Kantorovu00e1 M, Mru00e1zek J, Kreju010du00ed E, Stevens DA, Havlu00edu010dek V. Diagnosis of Aspergillosis in Horses.. J Fungi (Basel) 2023 Jan 25;9(2).
- Townsend M, Fowler B, Aulakh GK, Singh B. Expression of pentraxin 3 in equine lungs and neutrophils.. Can J Vet Res 2023 Jan;87(1):9-16.
- Shawaf T, Schuberth HJ, Hussen J. Immune cell composition of the bronchoalveolar lavage fluid in healthy and respiratory diseased dromedary camels.. BMC Vet Res 2022 Sep 21;18(1):353.
- Janssen P, Tosi I, Hego A, Maru00e9chal P, Marichal T, Radermecker C. Neutrophil Extracellular Traps Are Found in Bronchoalveolar Lavage Fluids of Horses With Severe Asthma and Correlate With Asthma Severity.. Front Immunol 2022;13:921077.
- Araneda OF. Horse Racing as a Model to Study the Relationship between Air Pollutants and Physical Performance.. Animals (Basel) 2022 Apr 28;12(9).
- Mahon E, Eiras-Diaz A, Mason S, Stabile F, Uriarte A. Case Report: Ventriculoperitoneal Shunting and Radiation Therapy Treatment in a Cat With a Suspected Choroid Plexus Tumor and Hypertensive Hydrocephalus.. Front Vet Sci 2022;9:828083.
- Borowska A, Wolska D, Niedzwiedz A, Borowicz H, Jaworski Z, Siemieniuch M, Szwaczkowski T. Some Genetic and Environmental Effects on Equine Asthma in Polish Konik Horses.. Animals (Basel) 2021 Aug 3;11(8).
- Shawaf T, Almubarak A, Alhumam N, Almathen F, Hussen J. Cytological analysis of tracheal wash and bronchoalveolar lavage fluid in health and respiratory disease in dromedary camels.. PeerJ 2021;9:e11723.
- Kurtz M, Paulin MV, Fournet A, Decambron A, Fabru00e8s V, Freiche V. Surgical treatment of a distal oesophageal stricture by mucosal radial incision and dilation in a kitten with secondary megaoesophagus.. JFMS Open Rep 2021 Jan-Jun;7(1):2055116921994516.
- Dixon CE, Bedenice D, Mazan MR. Comparison of Flowmetric Plethysmography and Forced Oscillatory Mechanics to Measure Airway Hyperresponsiveness in Horses.. Front Vet Sci 2020;7:511023.
- Ribitsch I, Baptista PM, Lange-Consiglio A, Melotti L, Patruno M, Jenner F, Schnabl-Feichter E, Dutton LC, Connolly DJ, van Steenbeek FG, Dudhia J, Penning LC. Large Animal Models in Regenerative Medicine and Tissue Engineering: To Do or Not to Do.. Front Bioeng Biotechnol 2020;8:972.
- Couetil L, Cardwell JM, Leguillette R, Mazan M, Richard E, Bienzle D, Bullone M, Gerber V, Ivester K, Lavoie JP, Martin J, Moran G, Niedu017awiedu017a A, Pusterla N, Swiderski C. Equine Asthma: Current Understanding and Future Directions.. Front Vet Sci 2020;7:450.
- Stucchi L, Alberti E, Stancari G, Conturba B, Zucca E, Ferrucci F. The Relationship between Lung Inflammation and Aerobic Threshold in Standardbred Racehorses with Mild-Moderate Equine Asthma.. Animals (Basel) 2020 Jul 27;10(8).
- Hue E, Orard M, Toquet MP, Depecker M, Couroucu00e9 A, Pronost S, Paillot R, Richard EA. Asymmetrical Pulmonary Cytokine Profiles Are Linked to Bronchoalveolar Lavage Fluid Cytology of Horses With Mild Airway Neutrophilia.. Front Vet Sci 2020;7:226.
- Popescu S, Lazar EA, Borda C, Niculae M, Sandru CD, Spinu M. Welfare Quality of Breeding Horses Under Different Housing Conditions.. Animals (Basel) 2019 Mar 5;9(3).
- Dauvillier J, Ter Woort F, van Erck-Westergren E. Fungi in respiratory samples of horses with inflammatory airway disease.. J Vet Intern Med 2019 Mar;33(2):968-975.
- da Palma RK, Fratini P, Schiavo Matias GS, Cereta AD, Guimaru00e3es LL, Anunciau00e7u00e3o ARA, de Oliveira LVF, Farre R, Miglino MA. Equine lung decellularization: a potential approach for in vitro modeling the role of the extracellular matrix in asthma.. J Tissue Eng 2018 Jan-Dec;9:2041731418810164.
- Bond S, Lu00e9guillette R, Richard EA, Couetil L, Lavoie JP, Martin JG, Pirie RS. Equine asthma: Integrative biologic relevance of a recently proposed nomenclature.. J Vet Intern Med 2018 Nov;32(6):2088-2098.
- Husulak ML, Manning ST, Meachem MD, Burgess HJ, Epp TY, Montgomery JB. Does antimicrobial therapy improve outcomes in horses with severe equine asthma and a positive tracheal wash bacterial culture?. Can J Vet Res 2018 Jul;82(3):184-191.
- Barton AK, Schulze T, Doherr MG, Gehlen H. Influence of bronchoalveolar lavage on thoracic radiography in the horse.. J Vet Sci 2018 Jul 31;19(4):563-569.
- Bond SL, Timsit E, Workentine M, Alexander T, Lu00e9guillette R. Upper and lower respiratory tract microbiota in horses: bacterial communities associated with health and mild asthma (inflammatory airway disease) and effects of dexamethasone.. BMC Microbiol 2017 Aug 23;17(1):184.
- da Silva KM, Otaka JNP, Gonu00e7alves CAP, Silva EGA, de Alencar NX, Lessa DAB. Association between exercise-induced pulmonary hemorrhage and inflammatory airway disease in polo ponies.. J Equine Sci 2017;28(2):55-59.
- Barton AK, Wirth C, Bondzio A, Einspanier R, Gehlen H. Are pulmonary hemostasis and fibrinolysis out of balance in equine chronic pneumopathies?. J Vet Sci 2017 Sep 30;18(3):349-357.
- Barton AK, Pelli A, Rieger M, Gehlen H. Procalcitonin as a biomarker in equine chronic pneumopathies.. BMC Vet Res 2016 Dec 9;12(1):281.
- Doubli-Bounoua N, Richard EA, Lu00e9on A, Pitel PH, Pronost S, Fortier G. Multiple molecular detection of respiratory viruses and associated signs of airway inflammation in racehorses.. Virol J 2016 Nov 29;13(1):197.
- Couu00ebtil LL, Cardwell JM, Gerber V, Lavoie JP, Lu00e9guillette R, Richard EA. Inflammatory Airway Disease of Horses--Revised Consensus Statement.. J Vet Intern Med 2016 Mar-Apr;30(2):503-15.
- Barton AK, Shety T, Bondzio A, Einspanier R, Gehlen H. Metalloproteinases and Their Tissue Inhibitors in Comparison between Different Chronic Pneumopathies in the Horse.. Mediators Inflamm 2015;2015:569512.
- Houtsma A, Bedenice D, Pusterla N, Pugliese B, Mapes S, Hoffman AM, Paxson J, Rozanski E, Mukherjee J, Wigley M, Mazan MR. Association between inflammatory airway disease of horses and exposure to respiratory viruses: a case control study.. Multidiscip Respir Med 2015;10:33.
- Miskovic Feutz M, Couetil LL, Riley CP, Zhang X, Adamec J, Raskin RE. Secretoglobin and Transferrin Expression in Bronchoalveolar Lavage Fluid of Horses with Chronic Respiratory Disease.. J Vet Intern Med 2015 Nov-Dec;29(6):1692-9.
- Bullone M, de Lagarde M, Vargas A, Lavoie JP. Serum Surfactant Protein D and Haptoglobin as Potential Biomarkers for Inflammatory Airway Disease in Horses.. J Vet Intern Med 2015 Nov-Dec;29(6):1707-11.
- Toombs-Ruane LJ, Riley CB, Kendall AT, Bolwell CF, Benschop J, Rosanowski SM. Antimicrobial Susceptibilities of Aerobic Isolates from Respiratory Samples of Young New Zealand Horses.. J Vet Intern Med 2015 Nov-Dec;29(6):1700-6.
- Leclere M, Lavoie-Lamoureux A, Lavoie JP. Acute phase proteins in racehorses with inflammatory airway disease.. J Vet Intern Med 2015 May-Jun;29(3):940-5.
- Nogradi N, Couetil LL, Messick J, Stochelski MA, Burgess JR. Omega-3 fatty acid supplementation provides an additional benefit to a low-dust diet in the management of horses with chronic lower airway inflammatory disease.. J Vet Intern Med 2015 Jan;29(1):299-306.
- Ivester KM, Couu00ebtil LL, Zimmerman NJ. Investigating the link between particulate exposure and airway inflammation in the horse.. J Vet Intern Med 2014 Nov-Dec;28(6):1653-65.
- Kehrli D, Jandova V, Fey K, Jahn P, Gerber V. Multiple hypersensitivities including recurrent airway obstruction, insect bite hypersensitivity, and urticaria in 2 warmblood horse populations.. J Vet Intern Med 2015 Jan;29(1):320-6.
- Richard EA, Depecker M, Defontis M, Leleu C, Fortier G, Pitel PH, Couroucu00e9-Malblanc A. Cytokine concentrations in bronchoalveolar lavage fluid from horses with neutrophilic inflammatory airway disease.. J Vet Intern Med 2014 Nov-Dec;28(6):1838-44.
- Mazan MR, Lascola K, Bruns SJ, Hoffman AM. Use of a novel one-nostril mask-spacer device to evaluate airway hyperresponsiveness (AHR) in horses after chronic administration of albuterol.. Can J Vet Res 2014 Jul;78(3):214-20.
- Kusano K, Hobo S, Ode H, Ishikawa Y. Tracheal Endoscopic and Cytological Findings and Blood Examination Results in Thoroughbred Racehorses Suspected to have Lower Respiratory Tract Disease.. J Equine Sci 2008;19(4):97-102.
- Ivester KM, Couu00ebtil LL, Moore GE, Zimmerman NJ, Raskin RE. Environmental exposures and airway inflammation in young thoroughbred horses.. J Vet Intern Med 2014 May-Jun;28(3):918-24.
- McConachie EL, Hart KA, Whelchel DD, Schroeder EL, Schott HC 2nd, Sanchez S. Pulmonary disease potentially associated with Nicoletella semolina in 3 young horses.. J Vet Intern Med 2014 May-Jun;28(3):939-43.
- Pacheco AP, Paradis MR, Hoffman AM, Hermida P, Sanchez A, Nadeau JA, Tufts M, Mazan MR. Age effects on blood gas, spirometry, airway reactivity, and bronchoalveolar lavage fluid cytology in clinically healthy horses.. J Vet Intern Med 2014 Mar-Apr;28(2):603-8.
- Bosshard S, Gerber V. Evaluation of coughing and nasal discharge as early indicators for an increased risk to develop equine recurrent airway obstruction (RAO).. J Vet Intern Med 2014 Mar-Apr;28(2):618-23.
- Zhang L, Franchini M, Wehrli Eser M, Jackson EK, Dip R. Increased adenosine concentration in bronchoalveolar lavage fluid of horses with lower airway inflammation.. Vet J 2012 Jul;193(1):268-70.
- Beekman L, Tohver T, Dardari R, Lu00e9guillette R. Evaluation of suitable reference genes for gene expression studies in bronchoalveolar lavage cells from horses with inflammatory airway disease.. BMC Mol Biol 2011 Jan 28;12:5.
- Brosnahan MM, Brooks SA, Antczak DF. Equine clinical genomics: A clinician's primer.. Equine Vet J 2010 Oct;42(7):658-70.
- Bates JH, Rincon M, Irvin CG. Animal models of asthma.. Am J Physiol Lung Cell Mol Physiol 2009 Sep;297(3):L401-10.
- Riihimu00e4ki M, Raine A, Elfman L, Pringle J. Markers of respiratory inflammation in horses in relation to seasonal changes in air quality in a conventional racing stable.. Can J Vet Res 2008 Oct;72(5):432-9.
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