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Home / Equine Research Bank / Clin Exp Vaccine Res / Influenza virus vaccine for neglected hosts: horses and dogs...
Clinical and experimental vaccine research2016; 5(2); 117-124; doi: 10.7774/cevr.2016.5.2.117

Influenza virus vaccine for neglected hosts: horses and dogs.

Abstract: This study provides information regarding vaccine research and the epidemiology of influenza virus in neglected hosts (horses and dogs). Equine influenza virus (EIV) causes a highly contagious disease in horses and other equids, and outbreaks have occurred worldwide. EIV has resulted in costly damage to the horse industry and has the ability of cross the host species barrier from horses to dogs. Canine influenza is a virus of equine or avian origin and infects companion animals that live in close contact with humans; this results in possible exposure to the seasonal epizootic influenza virus. There have been case reports of genetic reassortment between human and canine influenza viruses, which results in high virulence and the ability of transmission to ferrets. This emphasizes the need for vaccine research on neglected hosts to update knowledge on current strains and to advance technology for controlling influenza outbreaks for public health.
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Publication Date: 2016-07-29 PubMed ID: 27489801PubMed Central: PMC4969275DOI: 10.7774/cevr.2016.5.2.117Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research focuses on the development and importance of influenza virus vaccines for often overlooked hosts, specifically horses and dogs. The article highlights the potential for cross-species transmission and subsequent public health implications.

Equine Influenza Virus

  • The study began by emphasizing the impact of Equine Influenza Virus (EIV) on the horse industry worldwide. EIV is highly contagious among horses and other equine species, causing outbreaks and inflicting substantial financial losses.
  • The authors note that one of their concerns is the virus’s ability to cross species barriers. Specifically, it’s been recorded to make a leap from horses to dogs, which raises significant public health concerns due to the close interaction between dogs and humans.

Canine Influenza

  • Canine Influenza, according to the research, indicates a virus that primarily originates from horses or birds and infects dogs. Due to the close contact dogs have with humans, this presents the potential risk of humans being exposed to these seasonal epizootic influenza viruses.
  • The paper references case studies that showcase genetic reassortment between human and canine influenza viruses. This interaction between both species’ influenza viruses can lead to a virus with increased virulence, or disease-causing potential.’
  • Interestingly, it’s been noted that such a virus, resulting from the reassortment, also has the ability to be transmitted to ferrets, indicating a broader spread potential among different species.

Vaccine Research Importance

  • The study underlines the importance of ongoing research into vaccines for these ‘neglected hosts’ – horses and dogs.
  • Such research is crucial in keeping up-to-date knowledge on current strains of the viruses affecting these species. This would lead to improvements in the prevention and control of influenza outbreaks among animals attended closely by humans, and thus reduce the risk to public health.
  • The authors argue that it is a field deserving of more attention and resources, as it could have substantial implications for both animal health and public health, considering the potential for interspecies transmission of influenza viruses.

Cite This Article

APA
Na W, Yeom M, Yuk H, Moon H, Kang B, Song D. (2016). Influenza virus vaccine for neglected hosts: horses and dogs. Clin Exp Vaccine Res, 5(2), 117-124. https://doi.org/10.7774/cevr.2016.5.2.117

Publication

Clinical and experimental vaccine research
ISSN: 2287-3651
NlmUniqueID: 101592344
Country: Korea (South)
Language: English
Volume: 5
Issue: 2
Pages: 117-124

Researcher Affiliations

Na, Woonsung
  • College of Pharmacy, Korea University, Sejong, Korea.
Yeom, Minjoo
  • College of Pharmacy, Korea University, Sejong, Korea.
Yuk, Huijoon
  • College of Pharmacy, Korea University, Sejong, Korea.
Moon, Hyoungjoon
  • Research Unit, Green Cross Veterinary Products, Yongin, Korea.
Kang, Bokyu
  • Research Unit, Green Cross Veterinary Products, Yongin, Korea.
Song, Daesub
  • College of Pharmacy, Korea University, Sejong, Korea.

Conflict of Interest Statement

No potential conflict of interest relevant to this article was reported.

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