Inhalation Therapy in Horses.
Abstract: This article discusses the benefits and limitations of inhalation therapy in horses. Inhalation drug therapy delivers the drug directly to the airways, thereby achieving maximal drug concentrations at the target site. Inhalation therapy has the additional advantage of decreasing systemic side effects. Inhalation therapy in horses is delivered by the use of nebulizers or pressured metered dose inhalers. It also requires the use of a muzzle or nasal mask in horses. Drugs most commonly delivered through inhalation drug therapy in horses include bronchodilators, antiinflammatories, and antimicrobials.
Copyright © 2016 Elsevier Inc. All rights reserved.
Publication Date: 2017-03-23 PubMed ID: 28325181DOI: 10.1016/j.cveq.2016.11.007Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Review
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research article presents an in-depth study of the use, benefits, and limitations of inhalation therapy in horses. This medical treatment delivers targeted drugs directly to the animals’ airways, ensuring maximum effectiveness with reduced side effects. The approach relies on tools such as nebulizers or pressured metered dose inhalers, alongside a muzzle or nasal mask. Preferred for administering bronchodilators, antiinflammatories, and antimicrobials, inhalation therapy could significantly transform horse therapy.
Research Objective and Methodology
- The main goal of this research was to evaluate the efficacy, benefits, and limitations of inhalation drug therapy in horses.
- Inhalation therapy delivers medication directly to the airways which increases the concentration of the drug in the target area and reduces systemic side effects.
- Delivery systems include nebulizers or pressurized metered dose inhalers accompanied by a muzzle or nasal mask for the horse.
- Drugs administered through inhalation therapy are primarily bronchodilators, anti-inflammatories, and antimicrobials.
Key findings
- Inhalation therapy proves to be highly efficient since it maximizes the concentration of medicine at the target site and minimizes systemic side effects. These side effects can often be detrimental and limit the systemic use of certain drugs.
- For the treatment to be effectively implemented and accepted by the horse, a muzzle or nasal mask is necessary. This ensures the correct administration of the therapy and compliance of the animal.
- A variety of drug types can be administered this way. Bronchodilators, anti-inflammatories, and antimicrobials are the most commonly used medicines in inhalation therapy for horses.
Conclusion and Implications of the Research
- This research confirms the potential benefits of inhalation therapy for horses. It elucidates that inhalation therapy facilitates a targeted drug delivery system that minimizes systemic side effects, an outcome not possible with traditional systemic drug administration approaches.
- The findings contribute to the field of veterinary medicine, primarily in the area of equine health. By demonstrating the advantages and possibilities of inhalation therapy, the study can spur further research and uptake of this method in clinical practice.
- However, despite its benefits, inhalation therapy has its limitations. These include the need for specific equipment like nebulizers or pressurised inhalers and the requirement of a cooperative horse. The potential difficulty in sourcing, utilizing and maintaining this equipment, as well as overcoming horse resistance to the nasal mask or muzzle, may present practical barriers to this treatment’s widespread adoption.
Cite This Article
APA
Cha ML, Costa LR.
(2017).
Inhalation Therapy in Horses.
Vet Clin North Am Equine Pract, 33(1), 29-46.
https://doi.org/10.1016/j.cveq.2016.11.007 Publication
Researcher Affiliations
- Kulshan Veterinary Hospital, 8880 Benson Rd, Lynden, WA 98264, USA.
- William R. Pritchard Veterinary Medical Teaching Hospital, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA. Electronic address: lais.costa65@gmail.com.
MeSH Terms
- Administration, Inhalation
- Aerosols / administration & dosage
- Animals
- Bronchodilator Agents / administration & dosage
- Horse Diseases / drug therapy
- Horses
- Nebulizers and Vaporizers / veterinary
- Respiratory Therapy / veterinary
Citations
This article has been cited 9 times.- Morelli J, Hoby S, Heiderich E, Stettler M, Elzahaby D, Evans AL. Efficacy and adverse effects of three delivery methods for aerosolized salbutamol in anesthetized European moose (Alces alces alces): a case series. Acta Vet Scand 2026 Feb 8;68(1):11.
- Ozcan U, Tutuncu M. The Effect of Florfenicol Given by Nebulization in the Treatment of Naturally Infected Calves With Bovine Respiratory Disease Complex: Randomized Clinical Study. Vet Med Sci 2025 Mar;11(2):e70238.
- Egli P, Boone L, Huber L, Higgins C, Gaonkar PP, Arrington J, Naskou MC, Peroni J, Gordon J, Lascola KM. Pilot study characterizing a single pooled preparation of equine platelet lysate for nebulization in the horse. Front Vet Sci 2024;11:1488942.
- Baker AL, Arruda B, Palmer MV, Boggiatto P, Sarlo Davila K, Buckley A, Ciacci Zanella G, Snyder CA, Anderson TK, Hutter CR, Nguyen TQ, Markin A, Lantz K, Posey EA, Kim Torchetti M, Robbe-Austerman S, Magstadt DR, Gorden PJ. Dairy cows inoculated with highly pathogenic avian influenza virus H5N1. Nature 2025 Jan;637(8047):913-920.
- Talavera-López J, Tudela-González A, Muñoz-Prieto A. Use of a Capsaicin Cough Challenge Test to Compare Four Different Techniques for Nebulization Delivery in Cats. Vet Sci 2024 Jul 17;11(7).
- Magramane S, Vlahović K, Gordon P, Kállai-Szabó N, Zelkó R, Antal I, Farkas D. Inhalation Dosage Forms: A Focus on Dry Powder Inhalers and Their Advancements. Pharmaceuticals (Basel) 2023 Nov 28;16(12).
- Lemonnier LC, Couroucé A, Cessans M, Petit L, Cardwell JM, Barbazanges P, Toquet M-, Richard EA. Detection of fungi in the airways of horses according to the sample site: a methodological study. Vet Res Commun 2024 Feb;48(1):345-355.
- Minuto J, Bedenice D, Ceresia M, Zaghloul I, Böhlke M, Mazan MR. Clinical effects and pharmacokinetics of nebulized lidocaine in healthy horses. Front Vet Sci 2022;9:984108.
- de Wasseige S, Picotte K, Lavoie JP. Nebulized dexamethasone sodium phosphate in the treatment of horses with severe asthma. J Vet Intern Med 2021 May;35(3):1604-1611.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists