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The Veterinary clinics of North America. Equine practice1996; 12(2); 173-194; doi: 10.1016/s0749-0739(17)30278-x

Instrument sterilization, skin preparation, and wound management.

Abstract: Recent advances in instrument sterilization include the introduction of gas plasma sterilization and the increased use of glutaraldehyde. Gas plasma sterilization has the advantages of no toxic residue effects, reduced turnover time, and applicability for sterilization of heat- and moisture-sensitive instruments. Chlorhexidine gluconate (4%) appears to be a superior preoperative surgical scrub for both the surgeon and the patient because of its increased antimicrobial efficacy, residual activity, and minimal tissue reactions. There are many new wound dressings and topical medications for treatment of wounds, but the efficacy of most of these preparations has been evaluated only in humans, dogs, and cats. The ideal topical wound preparation and dressing for equine wounds, particularly wounds affecting the distal limb, have not yet been found.
Publication Date: 1996-08-01 PubMed ID: 8856873DOI: 10.1016/s0749-0739(17)30278-xGoogle Scholar: Lookup
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Summary

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This research article discusses the recent developments in instrument sterilization, pre-surgery skin preparation, and wound management, emphasizing on new mechanisms like gas plasma sterilization, using chlorhexidine gluconate as the surgical scrub, and a range of wound dressings and topical medications being evaluated.

Instrument Sterilization

  • The article brings focus on recent advances in instrument sterilization methods, particularly the introduction of gas plasma sterilization and the increased usage of glutaraldehyde.
  • Gas plasma sterilization is highlighted as an impactful method due to its lack of toxic residue, reduced turnover time, and its compatibility with heat- and moisture-sensitive instruments.
  • Glutaraldehyde is another method that has seen increased usage but the article does not expand further on it.

Skin Preparation

  • The paper also discusses preoperative surgical scrubbing techniques. Chlorhexidine gluconate, specifically the 4% solution, is mentioned as a superior preoperative surgical scrub for both the surgeon and the patient.
  • The reasons for the superiority of Chlorhexidine gluconate are its increased antimicrobial efficacy, its lasting activity, and negligible tissue reactions.

Wound Management

  • Regard to wound management, the article mentions the existence of various new wound dressings and topical medications. However, the author points out that these have been majorly evaluated in humans, dogs, and cats, with limited research available on their applicability on equines (horses).
  • The problem of finding an ideal topical wound preparation and dressing for equine wounds, especially wounds affecting the distal limb, is still unsolved according to this research.

Cite This Article

APA
Southwood LL, Baxter GM. (1996). Instrument sterilization, skin preparation, and wound management. Vet Clin North Am Equine Pract, 12(2), 173-194. https://doi.org/10.1016/s0749-0739(17)30278-x

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 12
Issue: 2
Pages: 173-194

Researcher Affiliations

Southwood, L L
  • Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, USA.
Baxter, G M

    MeSH Terms

    • Animals
    • Anti-Bacterial Agents / therapeutic use
    • Horse Diseases / drug therapy
    • Horse Diseases / microbiology
    • Horse Diseases / prevention & control
    • Horses / surgery
    • Postoperative Complications / microbiology
    • Postoperative Complications / prevention & control
    • Postoperative Complications / veterinary
    • Preoperative Care / methods
    • Preoperative Care / veterinary
    • Skin / drug effects
    • Sterilization / methods
    • Surgery, Veterinary / methods
    • Surgical Instruments / standards
    • Surgical Wound Infection / drug therapy
    • Surgical Wound Infection / prevention & control
    • Surgical Wound Infection / veterinary

    References

    This article includes 79 references

    Citations

    This article has been cited 5 times.
    1. Sharifi S, Munoz R, McElwain A, Mahmoudi N, Nisbet D, Johnson V, Asgari M, Vali H, Matoori S, Marjanovic J, Tomic-Canic M, Pastar I, Gould L, Attar P, Mahmoudi M. Glutaraldehyde-induced porcine model mimics human chronic wounds: insights into pathophysiology and therapeutic applications. Trends Biotechnol 2025 Nov 28;.
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    2. Ibrahim A, Hassan D, Kelany N, Kotb S, Soliman M. Validation of Three Different Sterilization Methods of Tilapia Skin Dressing: Impact on Microbiological Enumeration and Collagen Content. Front Vet Sci 2020;7:597751.
      doi: 10.3389/fvets.2020.597751pubmed: 33426019google scholar: lookup
    3. Park C, Park SW, Yun KD, Ji MK, Kim S, Yang YP, Lim HP. Effect of Plasma Treatment and Its Post Process Duration on Shear Bonding Strength and Antibacterial Effect of Dental Zirconia. Materials (Basel) 2018 Nov 9;11(11).
      doi: 10.3390/ma11112233pubmed: 30423984google scholar: lookup
    4. Cha S, Park YS. Plasma in dentistry. Clin Plasma Med 2014 Jul;2(1):4-10.
      doi: 10.1016/j.cpme.2014.04.002pubmed: 27030818google scholar: lookup
    5. Gunasekaran T, Nigusse T, Dhanaraju MD. Silver nanoparticles as real topical bullets for wound healing. J Am Coll Clin Wound Spec 2011 Dec;3(4):82-96.
      doi: 10.1016/j.jcws.2012.05.001pubmed: 24527370google scholar: lookup