Intelligence-based anti-doping from an equine biological passport.
Abstract: The move towards personalized medicine derived from individually focused clinical chemistry measurements has been translated by the human anti-doping movement over the past decade into developing the athlete biological passport. There is considerable potential for animal sports to adapt this model to facilitate an intelligence-based anti-doping system. Copyright © 2017 John Wiley & Sons, Ltd.
Copyright © 2017 John Wiley & Sons, Ltd.
Publication Date: 2017-04-17 PubMed ID: 28266147DOI: 10.1002/dta.2180Google Scholar: Lookup
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- Journal Article
Summary
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This research focuses on the translational potential of the human anti-doping system known as the athlete biological passport into animal sports, presumably for an efficient and personalised anti-doping mechanism.
Research Overview
- This research is centered around the concept of the “athlete biological passport” that is used in human sports to control doping. The authors examine the potential for applying this system to animal sports as a strategic approach against doping.
Athlete Biological Passport
- The Athlete Biological Passport is an individual, electronic record for professional athletes, in which profiles of biological markers of doping and results of doping tests are collated over a period of time.
- Anti-doping regulations in human sports have been incredibly strengthened over years. One of the novel methodologies used for such purposes is a system of athlete biological passport. This robust system uses an individual’s unique genetic makeup to create an effective and personalised anti-doping mechanism.
Translational Potential to Animal Sports
- The authors discuss the idea of adapting the athlete biological passport model for use in animal sports. While animal sports might not seem immediately analogous to human sports, major competitions do have high stakes with significant potential for various forms of cheating, including doping.
- The key idea explored by the researchers is the application of the intelligence-based anti-doping system in animal sports, drawing from the model used in human sports. The intelligence-based anti-doping system would potentially detect and deter drug misuse in animals using bio-markers.
Challenges and Potential
- Transferring such a system from humans to animals would not be without challenges, however. Differences in species, large numbers of animals in many competitive events and the lack of a unified, international anti-doping agency for animal sports all represent barriers to such a transfer.
- Despite these challenges, the authors note there is considerable potential to adapt the model of the athlete biological passport to animal sports, and this shows promise for overall improvements in animal welfare and fairness in competition.
Cite This Article
APA
Cawley AT, Keledjian J.
(2017).
Intelligence-based anti-doping from an equine biological passport.
Drug Test Anal, 9(9), 1441-1447.
https://doi.org/10.1002/dta.2180 Publication
Researcher Affiliations
- Australian Racing Forensic Laboratory, Racing NSW, Sydney, New South Wales, Australia.
- Australian Racing Forensic Laboratory, Racing NSW, Sydney, New South Wales, Australia.
MeSH Terms
- Animals
- Athletes
- Biological Evolution
- Biomarkers / chemistry
- Doping in Sports / prevention & control
- Horses
- Humans
- Sports / physiology
Citations
This article has been cited 7 times.- Cloteau C, Dervilly G, Loup B, Delcourt V, Kaabia Z, Bagilet F, Groseille G, Dauriac K, Fisher S, Popot MA, Garcia P, Le Bizec B, Bailly-Chouriberry L. Performance assessment of an equine metabolomics model for screening a range of anabolic agents. Metabolomics 2023 Apr 7;19(4):38.
- Tou K, Cawley A, Bowen C, Bishop DP, Fu S. Towards Non-Targeted Screening of Lipid Biomarkers for Improved Equine Anti-Doping. Molecules 2022 Dec 30;28(1).
- Tou K, Cawley A, Bowen C, Sornalingam K, Fu S. Measurements of hydrocortisone and cortisone for longitudinal profiling of equine plasma by liquid chromatography-tandem mass spectrometry. Drug Test Anal 2022 May;14(5):943-952.
- Keen B, Cawley A, Reedy B, Fu S. Metabolomics in clinical and forensic toxicology, sports anti-doping and veterinary residues. Drug Test Anal 2022 May;14(5):794-807.
- Klingberg J, Keen B, Cawley A, Pasin D, Fu S. Developments in high-resolution mass spectrometric analyses of new psychoactive substances. Arch Toxicol 2022 Apr;96(4):949-967.
- Skalny AV, Zaitseva IP, Gluhcheva YG, Skalny AA, Achkasov EE, Skalnaya MG, Tinkov AA. Cobalt in athletes: hypoxia and doping - new crossroads. J Appl Biomed 2019 Mar;17(1):28.
- Ishii H, Shigematsu R, Takemoto S, Ishikawa Y, Mizobe F, Nomura M, Arima D, Kunii H, Yuasa R, Yamanaka T, Tanabe S, Nagata SI, Yamada M, Leung GN. Quantification of osilodrostat in horse urine using LC/ESI-HRMS to establish an elimination profile for doping control. Bioanalysis 2024;16(17-18):947-958.
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