Malignant edema in horses.
Abstract: Malignant edema (clostridial myositis) was diagnosed in 9 horses with signs of illness that included fever, depression, painful muscular swellings, and toxemia. The infection followed intramuscular injections in 8 horses and developed in a puncture wound in 1 horse. Treatment consisted of surgical fenestration of the involved muscle, high doses of penicillin, nonsteroidal anti-inflammatory agents and analgesics, and supportive fluid therapy. Five horses recovered and 4 died. Those that died had advanced signs of the disease at admission.
Publication Date: 1985-10-01 PubMed ID: 4055491
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The paper is a study on Malignant edema (clostridial myositis) in horses, detailing diagnosis, treatment methods, and outcomes of the disease when contracted.
Overview
The research investigated clinical cases of malignant edema, also known as clostridial myositis, in nine horses. The disease’s symptoms, method of contraction, treatment methods, and consequential outcomes were all explored.
Symptoms and Cause
- The horses exhibited symptoms such as fever, depression, painful muscle swellings, and toxemia indicating illness.
- It was found that in most cases (8 out of 9), the infection had developed following intramuscular injections.
- In one case, the disease developed following a puncture wound.
Treatment
- The research outlines the treatment administered to the affected horses, which included surgical fenestration of the involved muscle. This means making a surgical cut in the diseased muscle to release the build-up of pressure or fluid.
- The treatment also included high doses of penicillin, which is an antibiotic often used to treat bacterial infections.
- Nonsteroidal anti-inflammatory agents and analgesics were used to alleviate inflammation and pain.
- Supportive fluid therapy, which is often used to correct electrolyte and fluid imbalances, was also given to the horses.
Outcomes
- The research discussed the outcomes of the disease and treatment. Five out of the nine horses treated made a recovery. The remaining four horses unfortunately died.
- The horses that lost their lives had advanced signs of the disease upon admission, suggesting the prognosis could be affected by the stage of the disease at which it is detected and treatment begins.
Cite This Article
APA
Rebhun WC, Shin SJ, King JM, Baum KH, Patten V.
(1985).
Malignant edema in horses.
J Am Vet Med Assoc, 187(7), 732-736.
Publication
Researcher Affiliations
MeSH Terms
- Animals
- Anti-Bacterial Agents / therapeutic use
- Clostridium Infections / diagnosis
- Clostridium Infections / drug therapy
- Clostridium Infections / veterinary
- Edema / diagnosis
- Edema / drug therapy
- Edema / etiology
- Edema / veterinary
- Horse Diseases / diagnosis
- Horse Diseases / drug therapy
- Horse Diseases / etiology
- Horses
- Humans
- Myositis / diagnosis
- Myositis / drug therapy
- Myositis / etiology
- Myositis / veterinary
Citations
This article has been cited 4 times.- Uzal FA, Navarro MA, Asin J, Henderson EE. Clostridial Diseases of Horses: A Review. Vaccines (Basel) 2022 Feb 17;10(2).
- Freitas NFQR, Otaka DY, Galvão CC, de Almeida DM, Ferreira MRA, Moreira Júnior C, Hidalgo MMMH, Conceição FR, Salvarani FM. Humoral Immune Response Evaluation in Horses Vaccinated with Recombinant Clostridium perfringens Toxoids Alpha and Beta for 12 Months. Toxins (Basel) 2021 Aug 13;13(8).
- Sacco SC, Ortega J, Navarro MA, Fresneda KC, Anderson M, Woods LW, Moore J, Uzal FA. Clostridium sordellii-associated gas gangrene in 8 horses, 1998-2019. J Vet Diagn Invest 2020 Mar;32(2):246-251.
- Farias LD, Azevedo Mda S, Trost ME, De La Côrte FD, Irigoyen LF, de Vargas AC. Acute myonecrosis in horse caused by Clostridium novyi type A. Braz J Microbiol 2014;45(1):221-4.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists