Managing chronic arthritis.
Abstract: Many compounds are being investigated for the control of symptoms of osteoarthritis in people and animals. Ideally, treatment should include analgesia, inflammation control, and chondroprotection. With further progress in this area, combination therapies tailored to the needs of the individual animal should enable us to maximize efficacy and minimize side effects. Only a few of the newer therapies and pharmaceutic agents have been investigated in the horse, however. With more rigorous investigation, they may be determined to be ineffective or unsafe. Meanwhile, as much information should be gathered from manufacturers as possible so as to ensure that appropriate recommendations are made.
Publication Date: 2003-01-09 PubMed ID: 12516926DOI: 10.1016/s0749-0739(02)00024-xGoogle Scholar: Lookup
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Summary
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The research investigates various compounds and pharmaceutical agents currently under study for managing chronic arthritis, particularly in horses. The focus is on finding therapy combinations that would effectively provide pain relief, control inflammation, and protect the joints, while minimizing side effects.
Therapy Strategies for Chronic Arthritis
- The research examines the management of chronic arthritis symptoms via different compounds in both humans and animals. These compounds are under consideration for their ability to provide pain relief, control inflammation, and protect the cartilage (chondroprotection).
- The goal is to develop treatment plans that can be adjusted according to an individual animal’s needs, effectively balancing the benefits of the treatment against potential side effects.
Application on Horses
- While several new therapies and pharmaceutic agents are under investigation, not many of them have been investigated specifically in horses yet. It’s critical because the effectiveness and safety of these treatments may vary in different species. Further rigorous investigation would allow scientists to determine whether these treatments are ineffective or unsafe for horses.
- The research emphasises the importance of gathering as much information as possible from pharmaceutical manufacturers. This data can be used to ensure that treatment recommendations for managing arthritis in horses are based on the most current, accurate and reliable information.
Importance and Future Direction
- This research has wide implications for the treatment of osteoarthritis among all mammals. By investigating and understanding the effects of various compounds and pharmaceutical agents, researchers may be able to develop more effective therapies for chronic arthritis in both humans and animals.
- Future research should continue to explore the efficacies and safety of these potential treatments, specifically for horses. This will ensure that treatment recommendations are suitable, safe, and tailored to the specific needs of the animal, leading to improved animal welfare and health.
Cite This Article
APA
Malone ED.
(2003).
Managing chronic arthritis.
Vet Clin North Am Equine Pract, 18(3), 411-437.
https://doi.org/10.1016/s0749-0739(02)00024-x Publication
Researcher Affiliations
- Department of Clinical and Population Sciences, 225K Veterinary Teaching Hospitals, 1365 Gortner Avenue, St. Paul, MN 55108, USA. malon001@tc.umn.edu
MeSH Terms
- Aging / physiology
- Analgesics / therapeutic use
- Animals
- Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
- Arthritis / drug therapy
- Arthritis / surgery
- Arthritis / therapy
- Arthritis / veterinary
- Female
- Horse Diseases / drug therapy
- Horse Diseases / surgery
- Horse Diseases / therapy
- Horses
- Male
- Osteoarthritis / drug therapy
- Osteoarthritis / surgery
- Osteoarthritis / therapy
- Osteoarthritis / veterinary
- Pain / drug therapy
- Pain / etiology
- Pain / veterinary
- Physical Conditioning, Animal
Citations
This article has been cited 3 times.- Broeckx SY, Seys B, Suls M, Vandenberghe A, Mariën T, Adriaensen E, Declercq J, Van Hecke L, Braun G, Hellmann K, Spaas JH. Equine Allogeneic Chondrogenic Induced Mesenchymal Stem Cells Are an Effective Treatment for Degenerative Joint Disease in Horses.. Stem Cells Dev 2019 Mar 15;28(6):410-422.
- Bembo F, Eraud J, Philandrianos C, Bertrand B, Silvestre A, Veran J, Sabatier F, Magalon G, Magalon J. Combined use of platelet rich plasma & micro-fat in sport and race horses with degenerative joint disease: preliminary clinical study in eight horses.. Muscles Ligaments Tendons J 2016 Apr-Jun;6(2):198-204.
- Broeckx S, Zimmerman M, Crocetti S, Suls M, Mariën T, Ferguson SJ, Chiers K, Duchateau L, Franco-Obregón A, Wuertz K, Spaas JH. Regenerative therapies for equine degenerative joint disease: a preliminary study.. PLoS One 2014;9(1):e85917.
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