Melanotic hamartoma of the hind brain in a riding horse.
Abstract: A 3 1/2-year-old bay gelding of the cob type showed nervous signs and coughing associated with breaking-in and exercise. At post-mortem examination, heavy melanin pigmentation of the meninges of the hind brain and the medulla was identified and, on histological examination, melanin-containing cells were found within connective tissue extending into the medulla. The lesion was considered to be a melanotic hamartoma.
Publication Date: 1990-02-01 PubMed ID: 2324345DOI: 10.1016/s0021-9975(08)80128-4Google Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Case Reports
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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This research article reports the case of a young horse presenting with nervous and respiratory symptoms, ultimately diagnosed with a specific type of brain tumor characterized by high melanin pigmentation, known as melanotic hamartoma.
Background
- The subject of the study is a 3 and a half-year-old gelding horse that started showing nervous and respiratory signs, including coughing during exercise.
The Diagnoses
- After the horse had passed away, a post-mortem analysis was performed. The results revealed heavy melanin pigmentation of the meninges, the protective layers around the brain, and the medulla, a part of the brainstem.
Histological Examination
- Upon further examination of the tissue under a microscope, it was discovered that the melanin-containing cells were embedded within the connective tissue, extending into the medulla. This is a critical characteristic of melanotic hamartoma, a specific type of noncancerous brain tumor.
Conclusion
- The research article concludes that the nervous and respiratory symptoms in the horse were possibly due to the diagnosed melanotic hamartoma.
Cite This Article
APA
Mair TS, Pearson GR.
(1990).
Melanotic hamartoma of the hind brain in a riding horse.
J Comp Pathol, 102(2), 239-243.
https://doi.org/10.1016/s0021-9975(08)80128-4 Publication
Researcher Affiliations
- Department of Veterinary Medicine, University of Bristol, School of Veterinary Science, Langford, Avon, U.K.
MeSH Terms
- Animals
- Blindness / etiology
- Blindness / veterinary
- Brain Neoplasms / pathology
- Brain Neoplasms / veterinary
- Hamartoma / pathology
- Hamartoma / veterinary
- Horse Diseases / pathology
- Horses
- Male
- Melanosis / pathology
- Melanosis / veterinary
- Meningeal Neoplasms / pathology
- Meningeal Neoplasms / veterinary
- Rhombencephalon
Grant Funding
- Wellcome Trust
Citations
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