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Home / Equine Research Bank / Animals (Basel) / No Worm Is an Island; The Influence of Commensal Gut Microbi...
Animals : an open access journal from MDPI2020; 10(12); 2309; doi: 10.3390/ani10122309

No Worm Is an Island; The Influence of Commensal Gut Microbiota on Cyathostomin Infections.

Abstract: The importance of the gut microbiome for host health has been the subject of intense research over the last decade. In particular, there is overwhelming evidence for the influence of resident microbiota on gut mucosal and systemic immunity; with significant implications for the outcome of gastrointestinal (GI) infections, such as parasitic helminths. The horse is a species that relies heavily on its gut microbiota for GI and overall health, and disturbances in this complex ecosystem are often associated with life-threatening disease. In turn, nearly all horses harbour parasitic helminths from a young age, the most prevalent of which are the small strongyles, or cyathostomins. Research describing the relationship between gut microbiota and cyathostomin infection is in its infancy, however, to date there is evidence of meaningful interactions between these two groups of organisms which not only influence the outcome of cyathostomin infection but have long term consequences for equine host health. Here, we describe these interactions alongside supportive evidence from other species and suggest novel theories and avenues for research which have the potential to revolutionize our approach to cyathostomin prevention and control in the future.
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Publication Date: 2020-12-05 PubMed ID: 33291496PubMed Central: PMC7762139DOI: 10.3390/ani10122309Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article explores the relationship between the gut microbiota and cyathostomin infection in horses, emphasizing the potential impact the microbiota could have on such infections and animal health.

Overview of Gut Microbiota and its Importance

  • The gut microbiome, or microbiota, is a community of microorganisms that live in the digestive tracts of animals. It plays an integral role in the overall health of the host.
  • This ecosystem’s importance for host health has been the subject of intense research in recent years, with evidence pointing to its influence on both gut mucosal and systemic immunity.
  • Gut microbiota can significantly influence the outcomes of gastrointestinal infections, including those caused by parasitic helminths, organisms that infect a host’s intestines.

Gut Microbiome and Horse Health

  • Horses, in particular, rely heavily on their gut microbiota for gastrointestinal and general health. Disruptions in this ecosystem can lead to potentially life-threatening diseases.
  • Almost every horse harbors parasitic helminths from an early age. The most prevalent of these are the small strongyles, also known as cyathostomins.

Exploring the Link Between Gut Microbiota and Cyathostomin Infection

  • The focus of this research paper is to explore the relationship between gut microbiota and cyathostomin infection in horses. This field of research is fairly new, with emerging evidence suggesting a serious interaction between these two groups of organisms.
  • These interactions could influence not only the outcome of a cyathostomin infection, but they may also have long-term repercussions for the health of the horse.

Implications of the Study and Future Research Prospects

  • The study outlines the interactions between the gut microbiota and cyathostomin infection based on available research and evidence from other species. They also propose new theories and future research paths.
  • The researchers believe that a deeper understanding of these interactions could potentially revolutionize preventative measures and control methods against cyathostomin infection in horses.

Cite This Article

APA
Walshe N, Mulcahy G, Hodgkinson J, Peachey L. (2020). No Worm Is an Island; The Influence of Commensal Gut Microbiota on Cyathostomin Infections. Animals (Basel), 10(12), 2309. https://doi.org/10.3390/ani10122309

Publication

Animals : an open access journal from MDPI
ISSN: 2076-2615
NlmUniqueID: 101635614
Country: Switzerland
Language: English
Volume: 10
Issue: 12
PII: 2309

Researcher Affiliations

Walshe, Nicola
  • School of Veterinary Medicine, University College Dublin, 4 Dublin, Ireland.
Mulcahy, Grace
  • School of Veterinary Medicine, University College Dublin, 4 Dublin, Ireland.
Hodgkinson, Jane
  • Institute of Infection and Global Health, University of Liverpool, Liverpool L69 7ZJ, UK.
Peachey, Laura
  • Bristol Veterinary School, Faculty of Health Sciences, University of Bristol, Langford BS40 5DU, UK.

Conflict of Interest Statement

The authors declare no conflict of interest.

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Citations

This article has been cited 3 times.
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  3. Slater R, Frau A, Hodgkinson J, Archer D, Probert C. A Comparison of the Colonic Microbiome and Volatile Organic Compound Metabolome of Anoplocephala perfoliata Infected and Non-Infected Horses: A Pilot Study.. Animals (Basel) 2021 Mar 9;11(3).
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