Optic axis determination by fibre-based polarization-sensitive swept-source optical coherence tomography.
Abstract: We describe a fibre-based variable-incidence angle (VIA) polarization-sensitive swept-source optical coherence tomography (PS-SS-OCT) system to determine the 3D optical axis of birefringent biological tissues. Single-plane VIA-PS-OCT is also explored which requires measurement of the absolute fast-axis orientation. A state-of-the-art PS-SS-OCT system with some improvements both in hardware and software was used to determine the apparent optical birefringence of equine tendon for a number of different illumination directions. Polar and azimuthal angles of cut equine tendon were produced by the VIA method and compared with the nominal values. A quarter waveplate (QWP) and equine tendon were used as test targets to validate the fast-axis measurements using the system. Polar and azimuthal angles of cut equine tendon broadly agreed with the expected values within about 8% of the nominal values. A theoretical and experimental analysis of the effect of the sample arm fibre on determination of optical axis orientation using a proposed definition based on the orientation of the eigenpolarization ellipse experimentally confirms that this algorithm only works correctly for special settings of the sample arm fibre. A proposed algorithm based on the angle between Stokes vectors on the Poincaré sphere is confirmed to work for all settings of the sample arm fibre. A calibration procedure is proposed to remove the sign ambiguity of the measured orientation and was confirmed experimentally by using the QWP.
Publication Date: 2011-01-25 PubMed ID: 21263175DOI: 10.1088/0031-9155/56/4/014Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The article discusses a novel method for determining the 3D optical axis of birefringent biological tissues using a special OCT (Optical Coherence Tomography) system. The newly developed system yielded broadly accurate results when tested with equine tendons, giving an error margin of about 8%.
Methodology
- The researchers used a Variable-Incidence Angle (VIA) polarization-sensitive swept-source optical coherence tomography (PS-SS-OCT) system to find out 3D optical axis of birefringent biological tissues, such as equine tendon.
- A part of the study involves the exploration of Single-plane VIA-PS-OCT, which requires determining the absolute fast-axis orientation.
- A PS-SS-OCT system with certain hardware and software improvements facilitated the determination of apparent optical birefringence of equine tendon from various illumination directions.
Testing
- The researchers applied the VIA method to determine the polar and azimuthal angles of cut equine tendon and compared these results with the nominal values.
- A quarter waveplate (QWP) and equine tendon served as the test targets to validate the fast-axis measurements taken by the system.
- The error margin found in the angles of cut equine tendon compared with the expected values fell within about 8% of the nominal values.
Sample Arm Fiber Impact
- Both theoretical and practical evaluation was carried out to understand the effect of sample arm fibre on the determination of optical axis orientation in the proposed system.
- An algorithm based on the orientation of the eigenpolarization ellipse was tested, and found effective only for special settings of the sample arm fibre.
- An alternative algorithm, based on the angle between Stokes vectors on the Poincaré sphere, was confirmed to be effective for all settings of the sample arm fibre.
Calibration
- A calibration procedure, intended to eliminate the sign ambiguity of the measured orientation, was proposed and experimentally verified using the QWP.
Cite This Article
APA
Lu Z, Kasaragod DK, Matcher SJ.
(2011).
Optic axis determination by fibre-based polarization-sensitive swept-source optical coherence tomography.
Phys Med Biol, 56(4), 1105-1122.
https://doi.org/10.1088/0031-9155/56/4/014 Publication
Researcher Affiliations
- Department of Materials Science and Engineering, The Kroto Research Institute, University of Sheffield, Sheffield, UK. z.lu@sheffield.ac.uk
MeSH Terms
- Animals
- Collagen / chemistry
- Optical Phenomena
- Tomography, Optical Coherence / instrumentation
- Tomography, Optical Coherence / methods
Citations
This article has been cited 6 times.- Li W, Narice BF, Anumba DO, Matcher SJ. Polarization-sensitive optical coherence tomography with a conical beam scan for the investigation of birefringence and collagen alignment in the human cervix.. Biomed Opt Express 2019 Aug 1;10(8):4190-4206.
- Chue-Sang J, Gonzalez M, Pierre A, Laughrey M, Saytashev I, Novikova T, Ramella-Roman JC. Optical phantoms for biomedical polarimetry: a review.. J Biomed Opt 2019 Mar;24(3):1-12.
- de Boer JF, Hitzenberger CK, Yasuno Y. Polarization sensitive optical coherence tomography - a review [Invited].. Biomed Opt Express 2017 Mar 1;8(3):1838-1873.
- Wang H, Lenglet C, Akkin T. Structure tensor analysis of serial optical coherence scanner images for mapping fiber orientations and tractography in the brain.. J Biomed Opt 2015 Mar;20(3):036003.
- Lu Z, Kasaragod D, Matcher SJ. Conical scan polarization-sensitive optical coherence tomography.. Biomed Opt Express 2014 Mar 1;5(3):752-62.
- Wang H, Zhu J, Akkin T. Serial optical coherence scanner for large-scale brain imaging at microscopic resolution.. Neuroimage 2014 Jan 1;84:1007-17.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists
