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The Veterinary clinics of North America. Equine practice2017; 33(2); 367-378; doi: 10.1016/j.cveq.2017.03.009

Osteochondritis Dissecans Development.

Abstract: This article reviews current knowledge of osteochondritis dissecans (OCD) development in horses, including normal cartilage development, early osteochondrosis pathogenesis, and factors that result in healing or advancement to OCD fragments. Discussion includes current theories, detection, and therapeutic options.
Publication Date: 2017-05-25 PubMed ID: 28551287DOI: 10.1016/j.cveq.2017.03.009Google Scholar: Lookup
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Summary

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This research focuses on understanding osteochondritis dissecans, a joint disorder in horses, and discusses current theories, methods for detection, and treatment options.

Osteochondritis Dissecans Development

The article seeks to throw light on how osteochondritis dissecans (OCD), a common joint condition in horses, is developed. The research delves into understanding the normal development of cartilage, the pathogenesis of early osteochondrosis, and the factors that affect the healing process or cause the disease to progress to OCD fragments.

  • Normal cartilage development: This section of the paper discusses the typical processes involved in cartilage development in horses. Understanding this process is essential because deviations from it often lead to medical conditions such as OCD.
  • Early pathogenesis of osteochondrosis: Osteochondrosis is a relatively common condition in growing horses, resulting from a disruption in the normal process of cartilage development. It often leads to the formation of OCD. The paper examines this progression early on, which can provide insights into preventing the condition from advancing.
  • Factors that result in healing or advancement to OCD fragments: The research identifies various factors that can either aid the healing process or cause the disease to advance into OCD fragments. These findings are crucial for early intervention, treatment, and prevention strategies.

Discussion on Detection and Therapeutic Options

The latter part of the paper discusses the existing theories about OCD. It questions the current assumptions and suggests areas where further research is needed.

  • Current Theories: The researchers explore current theories on the causes and development of OCD. This is vital for developing preventative measures and treatments.
  • Detection: The paper talks about different methods to detect the disorder in horses. Earlier detection of OCD can lead to more effective treatment and better outcomes.
  • Therapeutic Options: Various therapeutic options for treating OCD are discussed in the paper. These include surgical treatments, non-surgical treatments, and ongoing care routines to manage the condition and improve the horse’s quality of life.

The article concludes with a call for further research in this area to develop even more effective detection methods and therapeutic strategies.

Cite This Article

APA
Semevolos SA. (2017). Osteochondritis Dissecans Development. Vet Clin North Am Equine Pract, 33(2), 367-378. https://doi.org/10.1016/j.cveq.2017.03.009

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 33
Issue: 2
Pages: 367-378
PII: S0749-0739(17)30034-2

Researcher Affiliations

Semevolos, Stacy A
  • Oregon State University, College of Veterinary Medicine, 200B Magruder Hall, Corvallis, OR 97322, USA. Electronic address: stacy.semevolos@oregonstate.edu.

MeSH Terms

  • Animals
  • Biomarkers / metabolism
  • Cartilage, Articular / growth & development
  • Cartilage, Articular / physiology
  • Horse Diseases / diagnosis
  • Horse Diseases / etiology
  • Horse Diseases / therapy
  • Horses
  • Osteochondritis Dissecans / diagnosis
  • Osteochondritis Dissecans / etiology
  • Osteochondritis Dissecans / therapy
  • Osteochondritis Dissecans / veterinary
  • Osteogenesis / physiology
  • Physical Conditioning, Animal / physiology
  • Synovial Fluid / chemistry

Citations

This article has been cited 3 times.
  1. Grissom SK, Semevolos SA, Duesterdieck-Zellmer K. Role of cartilage and bone matrix regulation in early equine osteochondrosis.. Bone Rep 2023 Jun;18:101653.
    doi: 10.1016/j.bonr.2023.101653pubmed: 36632355google scholar: lookup
  2. Kajabi AW, Zbýň Š, Johnson CP, Tompkins MA, Nelson BJ, Takahashi T, Shea KG, Marette S, Carlson CS, Ellermann JM. Longitudinal 3T MRI T(2) * mapping of Juvenile osteochondritis dissecans (JOCD) lesions differentiates operative from non-operative patients-Pilot study.. J Orthop Res 2023 Jan;41(1):150-160.
    doi: 10.1002/jor.25343pubmed: 35430743google scholar: lookup
  3. Bourebaba L, Röcken M, Marycz K. Osteochondritis dissecans (OCD) in Horses - Molecular Background of its Pathogenesis and Perspectives for Progenitor Stem Cell Therapy.. Stem Cell Rev Rep 2019 Jun;15(3):374-390.
    doi: 10.1007/s12015-019-09875-6pubmed: 30796679google scholar: lookup