Paraneoplastic syndromes.
- Journal Article
- Review
Summary
This research article investigates the significance and clinical impacts of paraneoplastic syndromes in horses, often overshadowed due to the physical presence of malignant tumours. It presents a detailed review of the common syndromes that are likely to occur in this animal.
Article Overview
The research article focuses on the underappreciated sphere of equine health – paraneoplastic syndromes. These syndromes are not directly caused by the physical presence or the multiplication of cancer cells, but are triggered by the immune system’s response or by hormones or other substances produced by the tumor. The study omits the common notion of focusing solely on malignant tumours and, alternatively, lends importance to the health complications derived from these paraneoplastic syndromes.
- The author argues that paraneoplastic syndromes often result in greater suffering than the actual tumor. This conclusion is based on the clinical effects of these syndromes that can significantly deteriorate a horse’s health.
- Stressing the potentially severe nature of these syndromes, the article points out that these health issues might be the initial signs of malignancy. It suggests that the severity of these syndromes may sometimes prevent timely treatment for the underlying cancer.
- Through this paper, the author presents a comprehensive review of some of the most common instances of paraneoplastic syndromes likely to occur in horses. The aim here is to bring more recognition and understanding amongst researchers and veterinary practitioners about these under-reported health crises.
Significance of this Study
This study is of particular importance due to its unique focus. It fills an apparent gap in existing literature by paying attention to an under-studied area in equine health – paraneoplastic syndromes and their clinical effects. The findings from this study could potentially aid in early detection of these health issues, instigate appropriate therapies for underlying cancers, and ultimately improve the overall health management for horses.
Cite This Article
Publication
Researcher Affiliations
- Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, USA.
MeSH Terms
- Animals
- Cachexia / etiology
- Cachexia / veterinary
- Fever / etiology
- Fever / veterinary
- Hematologic Diseases / etiology
- Hematologic Diseases / veterinary
- Horse Diseases / etiology
- Horses
- Nervous System Diseases / etiology
- Nervous System Diseases / veterinary
- Osteoarthropathy, Secondary Hypertrophic / etiology
- Osteoarthropathy, Secondary Hypertrophic / veterinary
- Paraneoplastic Endocrine Syndromes / etiology
- Paraneoplastic Endocrine Syndromes / veterinary
- Paraneoplastic Syndromes / etiology
- Paraneoplastic Syndromes / veterinary
- Stomatitis / etiology
- Stomatitis / veterinary
Citations
This article has been cited 1 times.- Browne NS, Scarratt WK, Robertson J. Hypertrophic osteopathy secondary to metastatic ovarian adenocarcinoma in a mare. Can Vet J 2016 Dec;57(12):1237-1241.