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Primary cardiac hemangiosarcoma in a horse: echocardiographic and necropsy findings.

Abstract: Cardiac hemangiosarcoma, especially primary, is infrequently reported in the horse and remains a diagnostic challenge because of vague clinical signs and difficulty to reach an antemortem diagnosis. A 17-year-old American Quarter Horse gelding was presented with a history of tongue swelling and secondary aspiration pneumonia. Initial assessment indicated dehydration, and thoracic ultrasound revealed an abnormal structure within the myocardium alongside the previously suspected aspiration pneumonia. A subsequent, complete echocardiogram identified a large, heterogeneous, ill-defined mass invading and replacing the normal myocardium of the right ventricular free wall. Because of lack of improvement the horse was euthanized, and postmortem examination confirmed primary cardiac hemangiosarcoma with no further masses identified in other organs. This case is an unusual presentation of primary cardiac hemangiosarcoma for which echocardiography played a significant role in identifying a cardiac mass.
Publication Date: 2020-10-08 PubMed ID: 33176251DOI: 10.1016/j.jvc.2020.09.008Google Scholar: Lookup
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Summary

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The research deals with a rare case of primary cardiac hemangiosarcoma, a heart tumor, in a horse. Detected with the use of echocardiography, the study provides detailed diagnostic findings from an initial presentation of tongue swelling and dehydration to postmortem confirmation of the tumor with no further spread.

Introduction and Presentation

  • The research discusses a very rare occurrence of primary cardiac hemangiosarcoma, which is a type of heart tumor, in a 17-year old American Quarter Horse.
  • The case was initially presented as tongue swelling in the horse, followed by secondary aspiration pneumonia, a condition where foreign bodies are inhaled into the branches of the lungs.
  • The horse was also found to be severely dehydrated at the time of initial assessment.

Diagnostic Process

  • During the diagnostic process, thoracic ultrasound was initially used, which revealed an abnormal structure within the horse’s heart muscle which was suspected to be associated with aspiration pneumonia.
  • To gain further clarity on the condition, a complete echocardiogram was performed. This detailed heart imaging technique suggested presence of a large, heterogeneous, ill-defined mass invading and replacing the normal heart muscle of the right ventricular free wall.

Outcome and Postmortem Findings

  • Despite the detailed diagnosis, the condition of the horse did not show any improvement leading to the hard decision of euthanizing the animal to relieve it of the fetching pain.
  • After euthanization, a postmortem examination was conducted which confirmed that the abnormal mass was indeed a primary cardiac hemangiosarcoma.
  • Interestingly, no other masses were found in other organs, therefore classifying it as ‘primary’ that is originating from heart and not metastatic.

Significance of the Case

  • This case was particularly remarkable as it was identified as an unusual presentation of primary cardiac hemangiosarcoma in horses, a condition not commonly reported.
  • The role of echocardiography was found to be highly significant in identifying and confirming the heart tumor. This underscores the importance of such diagnostic tools in veterinary medicine.

Cite This Article

APA
Beaumier A, Dixon CE, Robinson N, Rush JE, Bedenice D. (2020). Primary cardiac hemangiosarcoma in a horse: echocardiographic and necropsy findings. J Vet Cardiol, 32, 66-72. https://doi.org/10.1016/j.jvc.2020.09.008

Publication

ISSN: 1875-0834
NlmUniqueID: 101163270
Country: Netherlands
Language: English
Volume: 32
Pages: 66-72
PII: S1760-2734(20)30085-0

Researcher Affiliations

Beaumier, A
  • Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, 200 Westboro Road, North Grafton, MA, 01536, USA.
Dixon, C E
  • Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, 200 Westboro Road, North Grafton, MA, 01536, USA.
Robinson, N
  • Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, 200 Westboro Road, North Grafton, MA, 01536, USA.
Rush, J E
  • Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, 200 Westboro Road, North Grafton, MA, 01536, USA.
Bedenice, D
  • Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, 200 Westboro Road, North Grafton, MA, 01536, USA. Electronic address: daniela.bedenice@tufts.edu.

MeSH Terms

  • Animals
  • Autopsy / veterinary
  • Diagnosis, Differential
  • Echocardiography / veterinary
  • Heart Neoplasms / diagnosis
  • Heart Neoplasms / veterinary
  • Hemangiosarcoma / diagnosis
  • Hemangiosarcoma / veterinary
  • Horse Diseases / diagnosis
  • Horse Diseases / diagnostic imaging
  • Horse Diseases / pathology
  • Horses
  • Male

Citations

This article has been cited 3 times.
  1. Townsend KS, Johnson PJ, Kuroki K. Head and neck squamous cell carcinoma with heterotopic ossification, lymphovascular invasion, and nodal and pulmonary metastases in a 23-year-old Morgan gelding. Can Vet J 2023 Jul;64(7):627-632.
    pubmed: 37397690
  2. Matos JI, Pitti L, Parra-Quijano M, Arencibia A, Ramírez G, Díaz-Bertrana ML. Integrative anatomical and two-dimensional ultrasonographic assessment of the heart in Shetland ponies. Front Vet Sci 2025;12:1721000.
    doi: 10.3389/fvets.2025.1721000pubmed: 41624284google scholar: lookup
  3. Selecky ME, Louie EW, Donnelly C, Finno CJ, Morgan JM. Reference Values and Association of Body Weight, Age, and Sex With Echocardiographic Measurements in Non-Athletic Quarter Horses. J Vet Intern Med 2025 Sep-Oct;39(5):e70237.
    doi: 10.1111/jvim.70237pubmed: 40931454google scholar: lookup