Rational selection of antimicrobial drugs for treatment of infections of horses.
Abstract: The goal of antimicrobial drug use is quite specific. Consideration of many microbe-related, host-related, and drug-related factors is necessary for appropriate selection and use of antimicrobial drugs in equine patients. The concepts and data presented in this article demonstrate that fact. At the risk of oversimplification, "The bug denotes the drug, and the horse directs the course."
Publication Date: 1987-04-01 PubMed ID: 3555728DOI: 10.1016/s0749-0739(17)30698-3Google Scholar: Lookup
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Summary
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The research article discusses the process of choosing the right antimicrobial drugs for treating infections in equine patients, taking into account various factors associated with the microbes, the host, and the drugs themselves.
Understanding the Research Article
- The primary objective of the research is to provide an enhanced understanding of how to select the right antimicrobial drug for treating infections in horses. The research brings attention to the multifaceted selection process that involves considering factors relating to the microorganism causing the infection, the traits of the horse, and the properties of the drug.
- The authors argue that the specific microorganism or ‘bug’ often indicates which drug should be used, while distinct factors about the horse, like health status and age, contribute to determining the course of treatment. Thus, the statement “The bug denotes the drug, and the horse directs the course” encapsulates this idea.
Key Concepts and Data
- The research utilizes a combination of theoretical concepts and empirical data to support its arguments. While the specifics of these data are not elaborated upon in the abstract, it is implied that the evidence points to a need for careful balance between pathogen, host, and drug factors while selecting an appropriate antimicrobial treatment for horses.
- These findings aim to increase the efficacy of prescriptions, by guiding veterinary pharmacologists and practitioners in making data-driven decisions during the selection process. This not only helps in combating the infection but also works towards preventing the development of drug-resistant strains of microbes.
Implications and Relevance
- The implications of this research are significant for veterinary medicine – particularly for equine specialists. The straightforward statement that “The bug denotes the drug, and the horse directs the course” encapsulates a crucial idea that can function as a guiding principle in the selection of antimicrobial drugs for treating equine infections.
- By following these guidelines, experts in the field can enhance the likelihood of successful treatment outcomes, minimize the potential for unnecessary side-effects, and stem the tide of antibiotic resistance – a threat that endangers both veterinary and human medicine.
Cite This Article
APA
Brumbaugh GW.
(1987).
Rational selection of antimicrobial drugs for treatment of infections of horses.
Vet Clin North Am Equine Pract, 3(1), 191-220.
https://doi.org/10.1016/s0749-0739(17)30698-3 Publication
Researcher Affiliations
MeSH Terms
- Animals
- Anti-Bacterial Agents / pharmacology
- Anti-Bacterial Agents / therapeutic use
- Bacteria / drug effects
- Bacterial Infections / drug therapy
- Bacterial Infections / veterinary
- Horse Diseases / drug therapy
- Horses
Citations
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