Science-in-brief: The 6th Havemeyer Workshop on Rhodococcus equi-A decade-long journey in advancing research into a major equine pathogen (2012-2023).

1. Vazquez‐Boland JA, Prescott JF, Meijer WG, Leadon DP, Hines SA. Rhodococcus equi comes of age.. Equine Vet J 2009;41(1):93–95.
2. Cauchard S, Giguère S, Venner M, Muscatello G, Cauchard J, Cohen ND. Rhodococcus equi research 2008–2012: report of the Fifth International Havemeyer Workshop.. Equine Vet J 2013;45(5):523–526.
3. von Bargen K, Scraba M, Krämer I, Ketterer M, Nehls C, Krokowski S. Virulence‐associated protein A from Rhodococcus equi is an intercompartmental pH‐neutralising virulence factor.. Cell Microbiol 2019;21:e12958.
4. Petrišič N, Kozorog M, Aden S, Podobnik M, Anderluh G. The molecular mechanisms of listeriolysin O‐induced lipid membrane damage.. Biochim Biophys Acta Biomembr 2021;1863:183604.
5. Takai S, Fukunaga N, Ochiai S, Sakai T, Sasaki Y, Tsubaki S. Isolation of virulent and intermediately virulent Rhodococcus equi from soil and sand on parks and yards in Japan.. J Vet Med Sci 1996;58(7):669–672.
6. Val‐Calvo J, Darcy J, Gibbons J, Creighton A, Egan C, Buckley T. International spread of multidrug‐resistant Rhodococcus equi.. Emerg Infect Dis 2022;28:1899–1903.
7. Sanz M, Loynachan A, Sun L, Oliveira A, Breheny P, Horohov DW. The effect of bacterial dose and foal age at challenge on Rhodococcus equi infection.. Vet Microbiol 2013;167:623–631.
8. Takai S, Sudo M, Sakai M, Suzuki K, Sasaki Y, Kakuda T. Isolation of Rhodococcus equi from the gastrointestinal contents of earthworms (family Megascolecidae).. Lett Appl Microbiol 2022;74(1):27–31.
9. Allegro AR, Barhoumi R, Bordin AI, Bray JM, Cohen ND. Uptake and replication in Acanthamoeba castellanii of a virulent (pVAPA‐positive) strain of Rhodococcus equi and its isogenic, plasmid‐cured strain.. Vet Microbiol 2021;257:109069.
10. Huber L, Giguère S, Berghaus LJ, Hanafi A, Ryan C. Fecal shedding of Rhodococcus equi in mares and foals after experimental infection of foals and effect of composting on concentrations of R. equi in contaminated bedding.. Vet Microbiol 2018;223:42–46.
11. Bordin AI, Huber L, Sanz MG, Cohen ND. Rhodococcus equi foal pneumonia: update on epidemiology, immunity, treatment and prevention.. Equine Vet J 2022;54(3):481–494.
12. Legere RM, Poveda C, Ott JA, Bray JM, Villafone EG, Petri da Silveira B. Intramuscular but not nebulized administration of a mRNA vaccine against Rhodococcus equi stimulated humoral immune responses in neonatal foals.. Am J Vet Res 2024;85(2):ajvr.23.09.0208.
    doi: 10.2460/ajvr.23.09.0208google scholar: lookup
13. Rakowska A, Cywinska A, Witkowski L. Current trends in understanding and managing equine Rhodococcosis.. Animals (Basel) 2020;10(10):1910.
14. Lankenfeld A, Weber C, Rohn K, Venner M. Kinetics of serum amyloid A during the treatment period of foals with pneumonia.. Pferdeheilkunde 2021;37(2):128–137.
15. Arnold‐Lehna D, Venner M, Berghaus LJ, Berghaus R, Giguère S. Changing policy to treat foals with Rhodococcus equi pneumonia in the later course of disease decreases antimicrobial usage without increasing mortality rate.. Equine Vet J 2020;52(4):531–537.
16. Rutenberg D, Venner M, Giguère S. Efficacy of Tulathromycin for the treatment of foals with mild to moderate bronchopneumonia. J Vet Intern Med. 2017;31:901–906.
17. Goebel B, Freise F, Venner M. Comparison of the efficacy of rifampin/azithromycin and rifampin/tulathromycin for the treatment of foals affected with pneumonia. Equine Vet Educ. 2022;34(1):e73–e77.
18. Wetzig M, Venner M, Giguère S. Efficacy of the combination of doxycycline and azithromycin for the treatment of foals with mild to moderate bronchopneumonia. Equine Vet J. 2020;52:613–619.
19. Venner M, Astheimer K, Lämmer M, Giguère S. Efficacy of mass antimicrobial treatment of foals with subclinical pulmonary abscesses associated with Rhodococcus equi. J Vet Intern Med. 2013;27(1):171–176.
20. Oren A, Arahal DR, Göker M, Moore ERB, Rossello‐Mora R, Sutcliffe IC. International code of nomenclature of prokaryotes. Prokaryotic code (2022 revision). Int J Syst Evol Microbiol. 2023;73(5a):005585. https://doi.org/10.1099/ijsem.0.005585
21. Sangal V, Goodfellow M, Jones AL, Sutcliffe IC. A stable home for an equine pathogen: valid publication of the binomial Prescottella equi gen. nov., comb. nov., and reclassification of four rhodococcal species into the genus Prescottella. Int J Syst Evol Microbiol. 2022;72(9):005551. https://doi.org/10.1099/ijsem.0.005551
22. Goodfellow M, Oren A, Sangal V, Sutcliffe IC. Is the bacterial genus name Rhodococcus Zopf 1891 illegitimate? Request for an opinion. Int J Syst Evol Microbiol. 2024;74(1):006251. https://doi.org/10.1099/ijsem.0.006251
23. Arahal D, Bull CT, Christensen H, Chuvochina M, Christopher Dunlap C, Montero‐Calasanz MC, et al. Judicial Opinion 130. Int J Syst Evol Microbiol. 2024;74(6):006414. https://doi.org/10.1099/ijsem.0.006414

Citations

1. Yerlikaya Z, Karagülle B, Otlu B, Muz A. From Paddock to Foal: Prevalence and Genotypic Diversity of Rhodococcus equi on Stud Farms in Türkiye.. Vet Sci 2026 Jan 10;13(1).
   doi: 10.3390/vetsci13010072pubmed: 41600728google scholar: lookup
2. Yerlikaya Z, Miranda-CasoLuengo R, Ó Gaora P, Meijer WG. Complete genome sequence of the saprophytic actinomycete Rhodococcus (Prescottella) soli DSD51W(T), closely related to the multi-host pathogen Rhodococcus (Prescottella) equi.. Microbiol Resour Announc 2024 Dec 12;13(12):e0059724.
   doi: 10.1128/mra.00597-24pubmed: 39470233google scholar: lookup