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The Veterinary clinics of North America. Equine practice2015; 31(3); 483-496; doi: 10.1016/j.cveq.2015.09.001

Sepsis and Septic Shock in the Equine Neonate.

Abstract: Sepsis and septic shock represent a major cause of morbidity and mortality in equine neonates and in all species. Early recognition of the condition is important, but definitive examination and laboratory variables to predict equine neonatal sepsis are lacking. Early and aggressive treatment should include broad-spectrum antimicrobial coverage, source control, and hemodynamic support. Field practitioners and intensive care clinicians work together in the management of this condition because the recognition and initial treatment should begin as early as possible.
Publication Date: 2015-11-28 PubMed ID: 26612744DOI: 10.1016/j.cveq.2015.09.001Google Scholar: Lookup
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Summary

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This research article explores the prevalent issue of sepsis and septic shock in newborn horses, noting these conditions significantly contribute to their illness and death rates. The article further investigates the challenges around early detection and stressing the need for immediate, all-encompassing medical intervention.

Research Purpose

  • The research article primarily aims to discuss the challenges and importance of early detection and aggressive treatment for sepsis and septic shock – two prevalent conditions in equine neonates (newborn horses) that result in high morbidity and mortality rates.

Sepsis and Septic Shock in Equine Neonates

  • Sepsis and septic shock are major health issues in newborn horses that can lead to serious illness (morbidity) and death (mortality).
  • These conditions affect not only equine neonates but also births in all species. The study, however, focuses on equine neonates.

Challenges in Early Recognition

  • The research clarifies that picking up the conditions early is significant to addressing them appropriately and minimizing their impact.
  • However, it raises concern about the inadequacy of definitive examination methods and laboratory variables that could predict sepsis in equine neonates, hence suggesting a need for more research and development in this area.

Treatment Recommendations

  • Treating sepsis and septic shock in newborn horses requires a prompt and aggressive approach. The research recommends broad-spectrum antimicrobial coverage, source control, and hemodynamic support, stressing that the earlier these measures are taken, the better.

Collaboration Required

  • The article encapsulates the necessity for field practitioners and intensive care clinicians to collaborate in the management of sepsis in equine neonates. Such collaborative efforts would ensure swift recognition and initiation of relevant treatment processes.

Cite This Article

APA
Fielding CL, Magdesian KG. (2015). Sepsis and Septic Shock in the Equine Neonate. Vet Clin North Am Equine Pract, 31(3), 483-496. https://doi.org/10.1016/j.cveq.2015.09.001

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 31
Issue: 3
Pages: 483-496

Researcher Affiliations

Fielding, Christopher Langdon
  • Loomis Basin Equine Medical Center, 2973 Penryn Road, Penryn, CA 95663, USA. Electronic address: langdonfielding@yahoo.com.
Magdesian, Kiragos Gary
  • Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, 2108 Tupper Hall, Davis, CA 95616, USA.

MeSH Terms

  • Animals
  • Animals, Newborn
  • Horse Diseases / diagnosis
  • Horse Diseases / pathology
  • Horses
  • Sepsis / diagnosis
  • Shock, Septic / veterinary

Citations

This article has been cited 5 times.
  1. Wilkins PA, Wong D, Slovis NM, Collins N, Barr BS, MacKenzie C, De Solis CN, Castagnetti C, Mariella J, Burns T, Perkins G, Delvescovo B, Sanchez LC, Kemper AM, Magdesian KG, Bedenice D, Taylor SD, Gold J, Dunkel B, Pranzo G, Constable PD. The Systemic Inflammatory Response Syndrome and Predictors of Infection and Mortality in 1068 Critically Ill Newborn Foals. J Vet Intern Med 2025 Mar-Apr;39(2):e70004.
    doi: 10.1111/jvim.70004pubmed: 40091577google scholar: lookup
  2. Casalta H, Bayrou C, Djebala S, Eppe J, Gille L, Gommeren K, Marduel E, Sartelet A, Seys C, Versyp J, Grulke S. Evaluation of Blood Lactate, Heart Rate, Blood Pressure, and Shock Index, and Their Association with Prognosis in Calves. Vet Sci 2024 Jan 20;11(1).
    doi: 10.3390/vetsci11010045pubmed: 38275927google scholar: lookup
  3. Freccero F, Di Maio C, Mariella J, Lanci A, Castagnetti C, Hallowell G. Assessment of the microvascular perfusion using sidestream dark-field imaging in healthy newborn foals. Vet Med Sci 2023 Jan;9(1):158-166.
    doi: 10.1002/vms3.1051pubmed: 36524796google scholar: lookup
  4. Colmer SF, Luethy D, Abraham M, Stefanovski D, Hurcombe SD. Utility of cell-free DNA concentrations and illness severity scores to predict survival in critically ill neonatal foals. PLoS One 2021;16(4):e0242635.
    doi: 10.1371/journal.pone.0242635pubmed: 33901192google scholar: lookup
  5. Sanmartí J, Armengou L, Viu J, Alguacil E, Civit S, Ríos J, Jose-Cunilleras E. Plasma iron concentrations and systemic inflammatory response syndrome in neonatal foals. J Vet Intern Med 2020 May;34(3):1325-1331.
    doi: 10.1111/jvim.15770pubmed: 32297679google scholar: lookup