Journal of the American Veterinary Medical Association2001; 219(7); 946-949; doi: 10.2460/javma.2001.219.946

Seroprevalence of antibodies against equine arteritis virus in horses residing in the United States and imported horses.

Abstract: To compare seroprevalence of antibodies against equine arteritis virus (EAV) in horses residing in the United States with that of imported horses. Methods: Serologic survey. Methods: Serum samples from 364 horses on 44 equine operations in California and 226 horses imported from various countries. Methods: Serum samples were collected from each imported horse and from up to 20 horses on each operation. For resident horses, the number of sampled horses on each operation was determined on the basis of the number of horses on the operation. Samples were tested for antibodies against EAV by use of a serum neutralization test. Results: 1.9% of resident horses and 18.6% of imported horses were seropositive to EAV, including 16.1% of imported stallions. Conclusions: Results indicate that the EAV seroprevalence of horses residing in California is considerably lower than that of imported horses, including imported stallions.
Publication Date: 2001-10-17 PubMed ID: 11601790DOI: 10.2460/javma.2001.219.946Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research investigates the prevalence of Equine Arteritis Virus (EAV) antibodies in United States-residing and imported horses, finding that imported horses have a significantly higher seroprevalence of the disease.

Research Methodology

  • The researchers collected serum samples from a total of 364 resident horses located in 44 equine operations in California and 226 horses imported from various countries.
  • For resident horses, the number of horses sampled in each operation was decided based on the total number of horses in the operation.
  • Imported horses were all tested for EAV antibodies.
  • Testing was conducted using a serum neutralization test, a common method used to detect antibodies against viruses in blood serum samples.

Findings

  • According to the study, 1.9% resident horses tested positive for EAV antibodies while 18.6% imported horses were found to have the disease.
  • When focusing on imported stallions, the seroprevalence was found to be slightly lower at 16.1%.

Conclusion

  • The study’s results suggest that there’s a significant difference in the prevalence of EAV antibodies between resident, particularly Californian horses, and imported horses. Equines imported into the US carry a much higher seroprevalence rate of EAV antibodies.
  • Such findings may suggest a disparity in disease management practices between the US and other countries, or reflect differing levels of EAV exposure in the imported horses’ places of origin.

Cite This Article

APA
Hullinger PJ, Gardner IA, Hietala SK, Ferraro GL, MacLachlan NJ. (2001). Seroprevalence of antibodies against equine arteritis virus in horses residing in the United States and imported horses. J Am Vet Med Assoc, 219(7), 946-949. https://doi.org/10.2460/javma.2001.219.946

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 219
Issue: 7
Pages: 946-949

Researcher Affiliations

Hullinger, P J
  • California Department of Food and Agriculture, Animal Health and Food Safety Services, Sacramento 95814, USA.
Gardner, I A
    Hietala, S K
      Ferraro, G L
        MacLachlan, N J

          MeSH Terms

          • Animals
          • Antibodies, Viral / blood
          • Arterivirus Infections / epidemiology
          • Arterivirus Infections / immunology
          • Arterivirus Infections / veterinary
          • California / epidemiology
          • Equartevirus / immunology
          • Equartevirus / isolation & purification
          • Female
          • Horse Diseases / blood
          • Horse Diseases / epidemiology
          • Horses
          • Male
          • Neutralization Tests / veterinary
          • Seroepidemiologic Studies

          Citations

          This article has been cited 7 times.
          1. Nam B, Mekuria Z, Carossino M, Li G, Zheng Y, Zhang J, Cook RF, Shuck KM, Campos JR, Squires EL, Troedsson MHT, Timoney PJ, Balasuriya UBR. Intrahost Selection Pressure Drives Equine Arteritis Virus Evolution during Persistent Infection in the Stallion Reproductive Tract.. J Virol 2019 Jun 15;93(12).
            doi: 10.1128/JVI.00045-19pubmed: 30918077google scholar: lookup
          2. Laziu0107 S, Lupuloviu0107 D, Gaudaire D, Petrovic T, Laziu0107 G, Hans A. Serological evidence of equine arteritis virus infection and phylogenetic analysis of viral isolates in semen of stallions from Serbia.. BMC Vet Res 2017 Nov 7;13(1):316.
            doi: 10.1186/s12917-017-1226-xpubmed: 29115996google scholar: lookup
          3. Balasuriya UB, Go YY, MacLachlan NJ. Equine arteritis virus.. Vet Microbiol 2013 Nov 29;167(1-2):93-122.
            doi: 10.1016/j.vetmic.2013.06.015pubmed: 23891306google scholar: lookup
          4. Go YY, Bailey E, Timoney PJ, Shuck KM, Balasuriya UB. Evidence that in vitro susceptibility of CD3+ T lymphocytes to equine arteritis virus infection reflects genetic predisposition of naturally infected stallions to become carriers of the virus.. J Virol 2012 Nov;86(22):12407-10.
            doi: 10.1128/JVI.01698-12pubmed: 22933293google scholar: lookup
          5. Go YY, Bailey E, Cook DG, Coleman SJ, Macleod JN, Chen KC, Timoney PJ, Balasuriya UB. Genome-wide association study among four horse breeds identifies a common haplotype associated with in vitro CD3+ T cell susceptibility/resistance to equine arteritis virus infection.. J Virol 2011 Dec;85(24):13174-84.
            doi: 10.1128/JVI.06068-11pubmed: 21994447google scholar: lookup
          6. Miszczak F, Shuck KM, Lu Z, Go YY, Zhang J, Sells S, Vabret A, Pronost S, Fortier G, Timoney PJ, Balasuriya UB. Evaluation of two magnetic-bead-based viral nucleic acid purification kits and three real-time reverse transcription-PCR reagent systems in two TaqMan assays for equine arteritis virus detection in semen.. J Clin Microbiol 2011 Oct;49(10):3694-6.
            doi: 10.1128/JCM.01187-11pubmed: 21832018google scholar: lookup
          7. MacLachlan NJ, Balasuriya UB. Equine viral arteritis.. Adv Exp Med Biol 2006;581:429-33.
            doi: 10.1007/978-0-387-33012-9_77pubmed: 17037573google scholar: lookup