Serum concentrations of selenium, copper, and zinc in neonatal foals: Influence of failure of passive transfer and age-related changes.

Abstract: An adequate supply of trace elements is very important for equine neonates, as deficiencies can lead to health problems and even death. Unassigned: This study investigated serum concentrations of selenium (Se), copper (Cu), and zinc (Zn) in neonatal foals up to the 8th day of life. The influences of disease, age, and failure of passive transfer (FPT) on these concentrations were analyzed. Unassigned: Serum concentrations of Se, Cu, and Zn were determined from blood samples of 93 foals by means of inductively coupled plasma mass spectrometry. The foals were divided into 2 groups based on health status: clinically sick ( = 51) and clinically healthy ( = 42). The latter group was further divided into foals with FPT ( = 20) and those without ( = 22). Unassigned: Mean serum concentrations for Se, Cu, and Zn were 60 ± 40 μg/L, 0.25 ± 0.22 mg/L, and 605 ± 285 μg/L, respectively. A significant influence of age on serum Cu concentration was observed ( < 0.0001). No differences were observed between any of the serum concentrations in clinically sick and clinically healthy foals on the 1st day of life. The FPT status was not associated with reduced serum concentrations of Se, Cu, or Zn. Unassigned: It is not necessary to supplement trace elements in all foals with FPT. Concentrations sériques de sélénium, de cuivre et de zinc chez les poulains nouveau-nés : influence de l'échec du transfert passif et des changements liés à l'âge. Unassigned: Un apport suffisant en oligo-éléments est très important pour les nouveau-nés équins, car des carences peuvent entraîner des problèmes de santé, voire la mort. Unassigned: Cette étude a examiné les concentrations sériques de sélénium (Se), de cuivre (Cu) et de zinc (Zn) chez les poulains nouveau-nés jusqu’au 8ème jour de vie. Les influences de maladies, de l’âge et de l’échec du transfert passif (FPT) sur ces concentrations ont été analysées. Unassigned: Les concentrations sériques de Se, Cu et Zn ont été déterminées à partir d’échantillons de sang de 93 poulains au moyen d’une spectrométrie de masse à plasma à couplage inductif. Les poulains ont été divisés en 2 groupes en fonction de leur état de santé: cliniquement malades ( = 51) et cliniquement sains ( = 42). Ce dernier groupe a été divisé en poulains avec FPT ( = 20) et ceux sans ( = 22). Unassigned: Les concentrations sériques moyennes de Se, Cu et Zn étaient respectivement de 60 ± 40 μg/L, 0,25 ± 0,22 mg/L et 605 ± 285 μg/L. Une influence significative de l’âge sur la concentration sérique de Cu a été observée ( < 0,0001). Aucune différence n’a été observée entre les concentrations sériques chez les poulains cliniquement malades et cliniquement sains au premier jour de leur vie. Le statut FPT n’était pas associé à une réduction des concentrations sériques de Se, Cu ou Zn. Unassigned: Il n’est pas nécessaire de supplémenter tous les poulains en oligo-éléments avec FPT.(Traduit par D Serge Messier).
Publication Date: 2024-05-02 PubMed ID: 38694739PubMed Central: PMC11017931
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  • Journal Article

Summary

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The research investigates the serum concentrations of selenium, copper, and zinc in newborn foals during their first eight days of life. It also studies the effect of disease, age, and the failure of passive transfer on these concentrations.

Objective and Methodology

  • The research seeks to understand the serum concentrations of selenium (Se), copper (Cu), and zinc (Zn) in neonatal foals up to eight days old. It aims to determine the effects of age, diseases, and failure of passive transfer (FPT) on these concentrations.
  • A total of 93 foals had their blood samples tested for Se, Cu, and Zn concentrations through a method called inductively coupled plasma mass spectrometry.
  • The foals were then split into two groups depending on their health status: clinically sick (51 foals) and clinically healthy (42 foals). The second group was segmented further into foals with FPT (20 foals) and those without it (22 foals).

Results

  • The study found that the average serum concentrations for Se, Cu, and Zn were 60 ± 40 μg/L, 0.25 ± 0.22 mg/L, and 605 ± 285 μg/L, respectively.
  • There was a significant impact of age on the serum Cu concentration ( < 0.0001).
  • No notable differences were observed in serum concentrations between the sick and healthy foals on their first day of life.
  • FPT status didn’t seem to affect the serum concentrations of Se, Cu, or Zn.

Conclusion

  • The study concluded that it is not vital to supplement all foals with FPT with trace elements.

Note: The text also includes a French translation of the abstract, which provides the same information as above in French. The research doesn’t make distinctions between the findings in any specific language version.

Cite This Article

APA
Stahl LT, Mu00fcller A, Krohn J, Bu00fcttner K, Wehrend A. (2024). Serum concentrations of selenium, copper, and zinc in neonatal foals: Influence of failure of passive transfer and age-related changes. Can Vet J, 65(5), 481-487.

Publication

ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 65
Issue: 5
Pages: 481-487

Researcher Affiliations

Stahl, Lydia T
  • Veterinary Clinic for Reproductive Medicine and Neonatology, Justus-Liebig-University Giessen, Frankfurter Str. 106, 35392 Gieu00dfen, Germany (Stahl, Krohn, Wehrend); Vet Med Labor GmbH IDEXX Laboratories, Humboldtstrasse 2, 70806 Kornwestheim, Germany (Mu00fcller); Unit for Biomathematics, Justus-Liebig-University Giessen, Frankfurter Str. 95, 35392 Gieu00dfen, Germany (Bu00fcttner).
Mu00fcller, Anja
  • Veterinary Clinic for Reproductive Medicine and Neonatology, Justus-Liebig-University Giessen, Frankfurter Str. 106, 35392 Gieu00dfen, Germany (Stahl, Krohn, Wehrend); Vet Med Labor GmbH IDEXX Laboratories, Humboldtstrasse 2, 70806 Kornwestheim, Germany (Mu00fcller); Unit for Biomathematics, Justus-Liebig-University Giessen, Frankfurter Str. 95, 35392 Gieu00dfen, Germany (Bu00fcttner).
Krohn, Judith
  • Veterinary Clinic for Reproductive Medicine and Neonatology, Justus-Liebig-University Giessen, Frankfurter Str. 106, 35392 Gieu00dfen, Germany (Stahl, Krohn, Wehrend); Vet Med Labor GmbH IDEXX Laboratories, Humboldtstrasse 2, 70806 Kornwestheim, Germany (Mu00fcller); Unit for Biomathematics, Justus-Liebig-University Giessen, Frankfurter Str. 95, 35392 Gieu00dfen, Germany (Bu00fcttner).
Bu00fcttner, Kathrin
  • Veterinary Clinic for Reproductive Medicine and Neonatology, Justus-Liebig-University Giessen, Frankfurter Str. 106, 35392 Gieu00dfen, Germany (Stahl, Krohn, Wehrend); Vet Med Labor GmbH IDEXX Laboratories, Humboldtstrasse 2, 70806 Kornwestheim, Germany (Mu00fcller); Unit for Biomathematics, Justus-Liebig-University Giessen, Frankfurter Str. 95, 35392 Gieu00dfen, Germany (Bu00fcttner).
Wehrend, Axel
  • Veterinary Clinic for Reproductive Medicine and Neonatology, Justus-Liebig-University Giessen, Frankfurter Str. 106, 35392 Gieu00dfen, Germany (Stahl, Krohn, Wehrend); Vet Med Labor GmbH IDEXX Laboratories, Humboldtstrasse 2, 70806 Kornwestheim, Germany (Mu00fcller); Unit for Biomathematics, Justus-Liebig-University Giessen, Frankfurter Str. 95, 35392 Gieu00dfen, Germany (Bu00fcttner).

MeSH Terms

  • Animals
  • Horses / blood
  • Selenium / blood
  • Copper / blood
  • Zinc / blood
  • Animals, Newborn / blood
  • Horse Diseases / blood
  • Female
  • Male
  • Aging / blood
  • Immunity, Maternally-Acquired
  • Trace Elements / blood

Citations

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