Spinal anesthetics and analgesics in the horse.
Abstract: In the past 10 years, there have been many recent advances in spinal techniques in horses, both epidural and subarachnoid, to identify drugs or drug combinations that have sensory effects without motor nerve paralysis, thus providing pain control without these horses becoming recumbent. Opioids, alpha-2 agonists, dissociative drugs, and others have been investigated. Many of these drugs, which have serious side effects when injected systemically in horses, have been shown to have useful analgesic effects when injected spinally. Morphine-like opioids have the greatest potential for spinal use as they produce long-lasting analgesia without motor effects. Often the doses used spinally are significantly lower than those needed for systemic effects.
Copyright © 2010 Elsevier Inc. All rights reserved.
Publication Date: 2010-11-09 PubMed ID: 21056299DOI: 10.1016/j.cveq.2010.07.005Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Review
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research article discusses the advancements in the use of spinal anesthetics and analgesics techniques in horses over the past decade. The focus of the research is on finding drug combinations that can offer pain relief without causing motor paralysis, thus preventing the horses from becoming recumbent.
Latest Techniques in Spinal Anesthesia and Analgesia in Horses
- The research mainly focused on the developments made in spinal techniques for horses, particularly epidural and subarachnoid procedures. These advancements serve the purpose of finding safe and efficient drugs or their combinations, which can help in sensory reduction without leading to motor nerve paralysis. This ensures that horses can have a proper pain control treatment without being rendered unable to move or stand.
Study of Opioids, Alpha-2 Agonists, Dissociative Drugs, and Others
- The study investigated several categories of drugs, including opioids, alpha-2 agonists, and dissociative drugs. Many of these drugs, dangerous if injected systemically, have been found to have beneficial analgesic effects when injected spinally. This implies that these drugs, when utilized correctly, can significantly alleviate pain in horses without causing harmful side effects.
The Potential of Morphine-like Opioids
- Morphine-like opioids have been identified as having great potential for spinal use due to their ability to produce lasting analgesia without affecting motor nerve functions. This characteristic makes them suitable as they can provide long-term relief from pain without incapacitating the horses or making them recumbent, thus leading to an improved quality of life for the animals.
Low Dosage Requirement for Spinal Effects
- Often, the doses required to achieve spinal effects were found to be significantly lower than those needed for systemic effects. This means that smaller amounts of these drugs can be used yet still achieve the desired effect, which not only reduces the potential for any negative side effects but also makes these treatments more cost-effective.
Cite This Article
APA
Natalini CC.
(2010).
Spinal anesthetics and analgesics in the horse.
Vet Clin North Am Equine Pract, 26(3), 551-564.
https://doi.org/10.1016/j.cveq.2010.07.005 Publication
Researcher Affiliations
- Departamento de Farmacologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Sarmento Leite, 500 Sala 202, 90046-902, Porto Alegre RS, Brazil. claudio.natalini@pq.cnpq.br
MeSH Terms
- Analgesia, Epidural / veterinary
- Analgesics / administration & dosage
- Analgesics / therapeutic use
- Analgesics, Opioid / administration & dosage
- Analgesics, Opioid / therapeutic use
- Anesthesia, Spinal / veterinary
- Anesthetics / administration & dosage
- Anesthetics / therapeutic use
- Animals
- Horse Diseases / drug therapy
- Horses
- Injections, Spinal / veterinary
- Subarachnoid Space
Citations
This article has been cited 9 times.- Nahas AE, Almubarak AI, Hagag U. Epidural lidocaine, butorphanol, and butorphanol - lidocaine combination in dromedary camels. BMC Vet Res 2023 Feb 16;19(1):51.
- Marzok M, Almubarak AI, Babiker H, Kandeel M, El-Hawari SF, El-Khodery S. Comparative evaluation of sedative and anti-nociceptive effects of epidural romifidine, romifidine-lidocaine, and lidocaine in donkeys (Equus asinus). Front Vet Sci 2022;9:966715.
- Douglas H, Midon M, Shroff K, Floriano D, Driessen B, Hopster K. Caudal epidural catheterization for pain management in 48 hospitalized horses: A descriptive study of demographics, complications, and outcomes. Front Vet Sci 2022;9:995299.
- Straticò P, Guerri G, Palozzo A, Varasano V, Petrizzi L. Current Use of Equine Laparoscopy in Urogenital Disorders: A Scoping Review of the Literature from 2000 to 2021. Vet Sci 2022 Jan 22;9(2).
- Watkins AR, Hopster K, Levine D, Hurcombe SD. Cervical Epidural Spinal Analgesia for Acute Management of Severe Unilateral Forelimb Lameness: Case Report. Front Vet Sci 2021;8:749713.
- Vullo C, Tambella AM, Meligrana M, Catone G. Analgesic and Sedative Effects of Epidural Lidocaine-Xylazine in Elective Bilateral Laparoscopic Ovariectomy in Standing Mule Mares. Animals (Basel) 2021 Aug 17;11(8).
- Hurcombe SD, Morris TB, VanderBroek AR, Habecker P, Wulster K, Hopster K. Cervical Epidural and Subarachnoid Catheter Placement in Standing Adult Horses. Front Vet Sci 2020;7:232.
- Yasine A, Ashenafi H, Geldhof P, Van Brantegem L, Vercauteren G, Bekana M, Tola A, Van Soom A, Duchateau L, Goddeeris B, Govaere J. Histopathological lesions in reproductive organs, distal spinal cord and peripheral nerves of horses naturally infected with Trypanosoma equiperdum. BMC Vet Res 2019 May 28;15(1):175.
- Steagall PVM, Simon BT, Teixeira Neto FJ, Luna SPL. An Update on Drugs Used for Lumbosacral Epidural Anesthesia and Analgesia in Dogs. Front Vet Sci 2017;4:68.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists